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The map label for this gene is murI

Identifier: 15889167

GI number: 15889167

Start: 1845785

End: 1846606

Strand: Reverse

Name: murI

Synonym: Atu1867

Alternate gene names: 15889167

Gene position: 1846606-1845785 (Counterclockwise)

Preceding gene: 159184955

Following gene: 159184954

Centisome position: 64.99

GC content: 62.53

Gene sequence:

>822_bases
ATGCTGAAGACGAGTGAGGCGGCGGCCGATGTGCTGAAACCGGTGCTGGTGTTCGATTCCGGCATTGGTGGGCTGACGGT
TCTGCGCGAGGCGCGGGTGCTGATGCCCGAGCGCGGTTTCATCTATGTGGCTGACGATGCGGGTTTTCCCTATGGCGGCT
GGGAAGAGGAGGCGCTGAAGACGCGCATTCTCTCGCTATTCGAAACGCTGCTGCAGGATTACAGCCCGGAGGTCTGCATC
ATCGCGTGCAACACCGCCTTCACGCTGGCCGGAGCCGATCTTCGCGCCCGGTTTCCGGACATGACTTTCGTCGGCACCGT
TCCCGCCATCAAGCCAGCCGCCGAGCGTACCCGTTCGGGTCTCGTCTCTGTTCTCGCAACGCCCGGCACCGTCAAGCGGG
CTTATACGCGCGATCTCATCCAGTCCTTTGCCACACAGTGTCATGTCCGCCTCGTAGGTTCGGAAAATCTGGCGCGTATG
GCCGAAAGCTGGATCAGGGGCGAGCCGGTTTCGGACGAGGCGGTGCTGGCCGAAATCGAACCCTGCTTCATCGACAGCGA
CGGCAAGCGCACCGATATCGTCGTGCTTGCCTGCACCCATTATCCCTTCATGGCCAATGTGTTTCGCCGGCTGGCGCCAT
GGCCGGTGGACTGGCTTGATCCCGCCGAGGCGATTGCGAGGCGGGCCCGCCATCTCGTGCCGCTGCCGCAGGATGCGGAA
CATCCCGATGGTTTCGACTTTGCCGTCTTCACCTCGGGCAAACCGGATTTCGCCACGCGGCGGCTGATGCAGGGTTTCGG
TCTCAGCGTCTCTTCGAACTGA

Upstream 100 bases:

>100_bases
GTTTTCCGCGGCGTGATCAGGTCGCTCGATCGTTTTCCCCGGCAGTGGCCAAAGAAGACGGGCAGGGCAGCGGGGCCGTT
GGCCGAGGGAGCAGGGGAGA

Downstream 100 bases:

>100_bases
CTGCCGCCATTCGAATGTTTGTTGCATTTTTGCATCTATTTTGCTGGTCTTTTGCAATTCGAGATTGCGACCACTTGTCG
CGCCGAATTTCCTGTGTAAG

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MLKTSEAAADVLKPVLVFDSGIGGLTVLREARVLMPERGFIYVADDAGFPYGGWEEEALKTRILSLFETLLQDYSPEVCI
IACNTAFTLAGADLRARFPDMTFVGTVPAIKPAAERTRSGLVSVLATPGTVKRAYTRDLIQSFATQCHVRLVGSENLARM
AESWIRGEPVSDEAVLAEIEPCFIDSDGKRTDIVVLACTHYPFMANVFRRLAPWPVDWLDPAEAIARRARHLVPLPQDAE
HPDGFDFAVFTSGKPDFATRRLMQGFGLSVSSN

Sequences:

>Translated_273_residues
MLKTSEAAADVLKPVLVFDSGIGGLTVLREARVLMPERGFIYVADDAGFPYGGWEEEALKTRILSLFETLLQDYSPEVCI
IACNTAFTLAGADLRARFPDMTFVGTVPAIKPAAERTRSGLVSVLATPGTVKRAYTRDLIQSFATQCHVRLVGSENLARM
AESWIRGEPVSDEAVLAEIEPCFIDSDGKRTDIVVLACTHYPFMANVFRRLAPWPVDWLDPAEAIARRARHLVPLPQDAE
HPDGFDFAVFTSGKPDFATRRLMQGFGLSVSSN
>Mature_273_residues
MLKTSEAAADVLKPVLVFDSGIGGLTVLREARVLMPERGFIYVADDAGFPYGGWEEEALKTRILSLFETLLQDYSPEVCI
IACNTAFTLAGADLRARFPDMTFVGTVPAIKPAAERTRSGLVSVLATPGTVKRAYTRDLIQSFATQCHVRLVGSENLARM
AESWIRGEPVSDEAVLAEIEPCFIDSDGKRTDIVVLACTHYPFMANVFRRLAPWPVDWLDPAEAIARRARHLVPLPQDAE
HPDGFDFAVFTSGKPDFATRRLMQGFGLSVSSN

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=230, Percent_Identity=40, Blast_Score=160, Evalue=9e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_AGRT5 (Q8UE93)

Other databases:

- EMBL:   AE007869
- PIR:   AI2805
- PIR:   H97584
- RefSeq:   NP_354848.1
- ProteinModelPortal:   Q8UE93
- SMR:   Q8UE93
- STRING:   Q8UE93
- GeneID:   1133905
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1867
- eggNOG:   COG0796
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- PhylomeDB:   Q8UE93
- ProtClustDB:   PRK00865
- BioCyc:   ATUM176299-1:ATU1867-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29981; Mature: 29981

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTSEAAADVLKPVLVFDSGIGGLTVLREARVLMPERGFIYVADDAGFPYGGWEEEALK
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHH
TRILSLFETLLQDYSPEVCIIACNTAFTLAGADLRARFPDMTFVGTVPAIKPAAERTRSG
HHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCHHHCCCCEEEEECCCCCCHHHHHHHHH
LVSVLATPGTVKRAYTRDLIQSFATQCHVRLVGSENLARMAESWIRGEPVSDEAVLAEIE
HHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCHHEEECC
PCFIDSDGKRTDIVVLACTHYPFMANVFRRLAPWPVDWLDPAEAIARRARHLVPLPQDAE
CEEECCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
HPDGFDFAVFTSGKPDFATRRLMQGFGLSVSSN
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLKTSEAAADVLKPVLVFDSGIGGLTVLREARVLMPERGFIYVADDAGFPYGGWEEEALK
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHH
TRILSLFETLLQDYSPEVCIIACNTAFTLAGADLRARFPDMTFVGTVPAIKPAAERTRSG
HHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCHHHCCCCEEEEECCCCCCHHHHHHHHH
LVSVLATPGTVKRAYTRDLIQSFATQCHVRLVGSENLARMAESWIRGEPVSDEAVLAEIE
HHHHHCCCCHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCCCCCCCCHHEEECC
PCFIDSDGKRTDIVVLACTHYPFMANVFRRLAPWPVDWLDPAEAIARRARHLVPLPQDAE
CEEECCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
HPDGFDFAVFTSGKPDFATRRLMQGFGLSVSSN
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194