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The map label for this gene is argS

Identifier: 15889018

GI number: 15889018

Start: 1697660

End: 1699417

Strand: Reverse

Name: argS

Synonym: Atu1711

Alternate gene names: 15889018

Gene position: 1699417-1697660 (Counterclockwise)

Preceding gene: 159184883

Following gene: 159184882

Centisome position: 59.81

GC content: 57.85

Gene sequence:

>1758_bases
ATGAACATTTTTGCCGATTTCGATACCAGGATCAAAAACGCGCTCGAGACCCTCGATCTCGTGAAAGAGAACCGCGAAAA
GGTCGATTTCAGTCGAATTACCGTCGAATCCCCGCGTGATCTCAGCCATGGCGATGTCGCAACCAATGCAGCCATGGTGC
TGGCGAAGCCGCTTGGCACCAATCCGCGCGCGCTTGCCGAACTCCTTGTGCCTGCACTCCAGGCGGATGGCGATGTCGAC
GGCGTCAATGTCGCGGGTCCCGGTTTCATCAATCTCAAGGTTTCCGTCGGTTACTGGCAGCGTCTATTGGCCGACATGAT
CGGGCAGGGCGTCGATTTCGGCCGCTCCACCGTCGGCGCCGGCCAGAAGATCAATGTCGAATATGTCTCCGCCAACCCGA
CCGGCCCGATGCATGTCGGCCATTGCCGTGGTGCTGTCGTGGGTGACACGCTGGCGAACCTGCTTGCATTCGCAGGTTAC
GGCGTCACCAAGGAATATTACATCAACGATGCCGGCTCGCAGATCGACGTGCTGGCCCGTTCCGTCTTCCTGCGTTACCG
CGAGGCGCTGGGCGAGGATATCGGCTCCATTCCGTCCGGTCTCTACCCCGGTGATTATCTCGTTCCGGTCGGCCAGGCGC
TGGCGGATGAATATGGCATCAAGCTGCGCGCCATGCCGGAAGAAAAATGGCTGCCGATCGTGAAAGACAAGGCGATCGAC
GCGATGATGGTGATGATCCGCGAGGATCTGGCGCTGCTCAATGTGCGGCACGACGTGTTCTTCTCGGAGCGCACGCTGCA
TGAGGGAAATGGCGGCCCGATCCTTTCGGCGATCAACGATCTCACCTTCAAGGGCCATGTCTACAAGGGCACGCTGCCAC
CGCCGAAGGGCGAATTGCCTGACGACTGGGAAGACCGCGAGCAGACGCTGTTCCGCTCCACGGAAGTGGGCGACGACATG
GACCGCGCGCTGATGAAGTCGGATGGTTCCTACACCTATTTCGCCGCCGACGTTGCCTATTTCAAGAACAAGTTCGACCG
CGGTTTTTCCGAGATGATCTATGTGCTCGGCGCCGACCATGGCGGTTACGTCAAGCGGCTGGAAGCCGTCGCGCGCGCCG
TTTCCGAAGGCAAGTCGAAGCTGACGGTGCTGCTCTGCCAGCTCGTCAAGCTGTTCCGTGACGGCGAGCCGGTGAAGATG
TCGAAACGCTCCGGCGACTTCGTCACACTGCGCGATGTTGTCGACGAAGTGGGTCGCGATCCCGTGCGATTCATGATGCT
CTATCGGAAGAATTCCGAGCCGCTGGACTTCGATTTCGCGAAAGTGACCGAACAATCGAAGGATAATCCGGTCTTTTACG
TGCAATATGCGCATGCCCGCTGCAAGTCGATCTTCCGCCAGGCGCAGGAGGCGTTTCCGGGCCTTGCGCCGTCTGCCGAA
GACATGGCGGCGTCTGTTGCTTTGATTAGCGATATCAACGAGTTGCAGCTGGTTGCGAAGCTCGCCGAATATCCGCGTCT
GATCGAATCCGCGGCCCTTTCGCATGAGCCGCACAGGCTTGCTTTTTACCTTTATGATCTCGCCGGTTCCTTCCATGGGC
ACTGGAACAAAGGCAAAGACCATCAGGAATTACGTTTTATTAACGATAAAAACCGAGAATTGAGCATTGCCAGACTCGGG
CTGGTGAATGCTGTCGCGAATGTTTTGAAGTCCGGCCTTACGCTTTTAGGAGCGGACGCACCTGACGAAATGCGATAA

Upstream 100 bases:

>100_bases
TTGACCACACTCCCGATTTGCGATAGGGCAGCGGGCGATCGCGAAGCCACCCGGTTATGACGACCGAGACAAACAGAAGC
CCTTCGCGCAGGTTGGAACG

Downstream 100 bases:

>100_bases
CATATCACCATTATTTGCTCACAATACGCTGGCAAGAGCTGCAATGCGTAGATGGTGGAACACGTAATGGTCGAAAAAAA
TGTCGCGTATAACCGGGACG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGTNPRALAELLVPALQADGDVD
GVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGAGQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGY
GVTKEYYINDAGSQIDVLARSVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELPDDWEDREQTLFRSTEVGDDM
DRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADHGGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKM
SKRSGDFVTLRDVVDEVGRDPVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKDHQELRFINDKNRELSIARLG
LVNAVANVLKSGLTLLGADAPDEMR

Sequences:

>Translated_585_residues
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGTNPRALAELLVPALQADGDVD
GVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGAGQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGY
GVTKEYYINDAGSQIDVLARSVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELPDDWEDREQTLFRSTEVGDDM
DRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADHGGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKM
SKRSGDFVTLRDVVDEVGRDPVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKDHQELRFINDKNRELSIARLG
LVNAVANVLKSGLTLLGADAPDEMR
>Mature_585_residues
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGTNPRALAELLVPALQADGDVD
GVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGAGQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGY
GVTKEYYINDAGSQIDVLARSVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELPDDWEDREQTLFRSTEVGDDM
DRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADHGGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKM
SKRSGDFVTLRDVVDEVGRDPVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKDHQELRFINDKNRELSIARLG
LVNAVANVLKSGLTLLGADAPDEMR

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=140, Percent_Identity=32.8571428571429, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788184, Length=608, Percent_Identity=25.9868421052632, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71985061, Length=608, Percent_Identity=24.0131578947368, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71985068, Length=558, Percent_Identity=24.1935483870968, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320548, Length=572, Percent_Identity=25, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18859963, Length=591, Percent_Identity=24.3654822335025, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_AGRT5 (Q8UEP4)

Other databases:

- EMBL:   AE007869
- PIR:   AI2786
- PIR:   C97566
- RefSeq:   NP_354699.1
- ProteinModelPortal:   Q8UEP4
- STRING:   Q8UEP4
- GeneID:   1133749
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1711
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- PhylomeDB:   Q8UEP4
- ProtClustDB:   PRK01611
- BioCyc:   ATUM176299-1:ATU1711-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 64633; Mature: 64633

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHCCCEEEECCCCC
NPRALAELLVPALQADGDVDGVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGA
CHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCHHCCC
GQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGYGVTKEYYINDAGSQIDVLAR
CCEEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
SVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCHHHCCCHHHHHHHH
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELP
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHCCEEECEEEECCCCCCCCCCC
DDWEDREQTLFRSTEVGDDMDRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADH
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHEEEEEECCC
GGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKMSKRSGDFVTLRDVVDEVGRD
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEHHHHHHHHCCC
PVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHH
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCC
HQELRFINDKNRELSIARLGLVNAVANVLKSGLTLLGADAPDEMR
CCHHHEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MNIFADFDTRIKNALETLDLVKENREKVDFSRITVESPRDLSHGDVATNAAMVLAKPLGT
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHCCCEEEECCCCC
NPRALAELLVPALQADGDVDGVNVAGPGFINLKVSVGYWQRLLADMIGQGVDFGRSTVGA
CHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEHHHHHHHHHHHHCCCCCCCCHHCCC
GQKINVEYVSANPTGPMHVGHCRGAVVGDTLANLLAFAGYGVTKEYYINDAGSQIDVLAR
CCEEEEEEEECCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
SVFLRYREALGEDIGSIPSGLYPGDYLVPVGQALADEYGIKLRAMPEEKWLPIVKDKAID
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCEEEECCHHHCCCHHHHHHHH
AMMVMIREDLALLNVRHDVFFSERTLHEGNGGPILSAINDLTFKGHVYKGTLPPPKGELP
HHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHCCEEECEEEECCCCCCCCCCC
DDWEDREQTLFRSTEVGDDMDRALMKSDGSYTYFAADVAYFKNKFDRGFSEMIYVLGADH
CCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHEEEEEECCC
GGYVKRLEAVARAVSEGKSKLTVLLCQLVKLFRDGEPVKMSKRSGDFVTLRDVVDEVGRD
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEHHHHHHHHCCC
PVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCKSIFRQAQEAFPGLAPSAE
HHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHH
DMAASVALISDINELQLVAKLAEYPRLIESAALSHEPHRLAFYLYDLAGSFHGHWNKGKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCCCC
HQELRFINDKNRELSIARLGLVNAVANVLKSGLTLLGADAPDEMR
CCHHHEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194