Click here to switch to the map view.

The map label for this gene is gltA [H]

Identifier: 15888718

GI number: 15888718

Start: 1385187

End: 1386476

Strand: Reverse

Name: gltA [H]

Synonym: Atu1392

Alternate gene names: 15888718

Gene position: 1386476-1385187 (Counterclockwise)

Preceding gene: 159184743

Following gene: 15888698

Centisome position: 48.79

GC content: 60.08

Gene sequence:

>1290_bases
ATGACGGAAAAAAGCGCTACAGTGACACTTGGCGAAAAGCAGGTGGAACTCCCGGTCAGGGAAGGCACGATTGGACCAAG
CGTCGTCGATATCGCCACGCTCTACAAGCACACGGGCTCCTTCACCTACGACCCGGGTTTCACGTCGACGGCCTCCTGCG
AATCCAAGATCACCTATATCGACGGTGACGAGGGCGTTCTCCTGCATCGTGGTTTCCCCATCGAGCAACTGGCTGAACAG
GGCGACTTCCTCGAAACCTGCTATCTGCTGCTCTACGGCGAACTGCCGACGGCTGCGCAGAAGAAGGATTTCGACACCCG
CGTCACGCGCCACACCATGGTGCATGAGCAGATGAGCCGCTTCTTCACCGGCTATCGTCGCGACGCACACCCGATGGCCG
TCATGTGCGGCACGGTCGGCGCTCTCTCGGCCTTCTATCACGACTCGACGGACATCACCGATCCGCACCAGCGCATGGTC
GCTTCGCTGCGCATGATCGCGAAGATGCCGACGATCGCCGCCATGGCCTACAAGTACCATATCGGCCAGCCCTTCGTTTA
CCCGAAGAACGATCTGGATTACGCCTCCAACTTCCTGCACATGTGCTTTGCCGTGCCGTGCGAGGACTACAAGGTGGACC
CGGTTCTGGCCCGCGCCATGGATCGCATCTTCATCCTGCATGCCGATCACGAGCAGAACGCCTCCACCTCCACGGTGCGT
CTTGCCGGTTCGTCGGGTGCAAATCCGTTCGCCTGTATCGCGGCTGGCATCGCCTGCCTCTGGGGTCCGGCTCACGGCGG
CGCCAACGAAGCGGCGCTCAACATGCTGAACGAGATCGGCTCTGTCGACCGCATCCCGGAATATATCGCCCGCGCCAAGG
ACAAGAACGATCCGTTCCGCCTGATGGGCTTTGGCCACCGCGTCTACAAAAACTACGACCCGCGCGCCAAGATCATGCAG
AAGACGATGTACGAAGTGCTGGAAGCCACCGGCAATTCCGACGATCCGATCATGCAGGTCGCGCTCGAACTGGAAAAGAT
CGCCCTTTCCGACCCATACTTCGTCGAAAAGAAGCTCTACCCGAATGTCGACTTCTATTCGGGCATCACGCTGAAGGCGC
TCGGCTTCCCCACCACCATGTTCACCGTTCTCTTCGCTCTCGCCCGCACCGTCGGCTGGATCGCACAGTGGAACGAAATG
ATCGAAGATCCGCAGCAGCGCATCGGCCGTCCGCGCCAGCTCTATACGGGCGCCGGCAAGCGCGATTACGTTCCGGTTTC
CAAGCGTTAA

Upstream 100 bases:

>100_bases
ATAGCTTGGCATCGGCGCCAGGATCATATAGCTAATCGGTAGACGCTTAACCGCGAGGCGTGTCTCAACGCCTCCACCCG
CATGTTCTCGGAGGATCAGT

Downstream 100 bases:

>100_bases
GCCACGAAACCCTGTAAGATCAAAGGCCGGCAGGTTTTCACCCGCCGGCCTTTTTGTTGGGCGTCTCCGCGATATTTCTC
AGTGGCGCGCAGCAACGCCG

Product: type II citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTEKSATVTLGEKQVELPVREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYIDGDEGVLLHRGFPIEQLAEQ
GDFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSRFFTGYRRDAHPMAVMCGTVGALSAFYHDSTDITDPHQRMV
ASLRMIAKMPTIAAMAYKYHIGQPFVYPKNDLDYASNFLHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLNEIGSVDRIPEYIARAKDKNDPFRLMGFGHRVYKNYDPRAKIMQ
KTMYEVLEATGNSDDPIMQVALELEKIALSDPYFVEKKLYPNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEM
IEDPQQRIGRPRQLYTGAGKRDYVPVSKR

Sequences:

>Translated_429_residues
MTEKSATVTLGEKQVELPVREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYIDGDEGVLLHRGFPIEQLAEQ
GDFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSRFFTGYRRDAHPMAVMCGTVGALSAFYHDSTDITDPHQRMV
ASLRMIAKMPTIAAMAYKYHIGQPFVYPKNDLDYASNFLHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQNASTSTVR
LAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLNEIGSVDRIPEYIARAKDKNDPFRLMGFGHRVYKNYDPRAKIMQ
KTMYEVLEATGNSDDPIMQVALELEKIALSDPYFVEKKLYPNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEM
IEDPQQRIGRPRQLYTGAGKRDYVPVSKR
>Mature_428_residues
TEKSATVTLGEKQVELPVREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYIDGDEGVLLHRGFPIEQLAEQG
DFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSRFFTGYRRDAHPMAVMCGTVGALSAFYHDSTDITDPHQRMVA
SLRMIAKMPTIAAMAYKYHIGQPFVYPKNDLDYASNFLHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQNASTSTVRL
AGSSGANPFACIAAGIACLWGPAHGGANEAALNMLNEIGSVDRIPEYIARAKDKNDPFRLMGFGHRVYKNYDPRAKIMQK
TMYEVLEATGNSDDPIMQVALELEKIALSDPYFVEKKLYPNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEMI
EDPQQRIGRPRQLYTGAGKRDYVPVSKR

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=399, Percent_Identity=26.5664160401003, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1786939, Length=430, Percent_Identity=68.3720930232558, Blast_Score=626, Evalue=1e-180,
Organism=Escherichia coli, GI1786527, Length=370, Percent_Identity=29.1891891891892, Blast_Score=152, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17555174, Length=403, Percent_Identity=26.7990074441687, Blast_Score=109, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319850, Length=334, Percent_Identity=29.6407185628743, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324328, Length=338, Percent_Identity=26.9230769230769, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6325257, Length=402, Percent_Identity=25.1243781094527, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640126, Length=408, Percent_Identity=26.7156862745098, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24640124, Length=408, Percent_Identity=26.7156862745098, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356863, Length=389, Percent_Identity=27.2493573264781, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 47941; Mature: 47810

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00480 CITRATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKSATVTLGEKQVELPVREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYI
CCCCCCEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEE
DGDEGVLLHRGFPIEQLAEQGDFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSR
ECCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FFTGYRRDAHPMAVMCGTVGALSAFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYKYH
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHC
IGQPFVYPKNDLDYASNFLHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQNASTSTVR
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLNEIGSVDRIPEYIARAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNYDPRAKIMQKTMYEVLEATGNSDDPIMQVALELEKIALSDPYFVEKKLY
EEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHCC
PNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEMIEDPQQRIGRPRQLYTGAGK
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEECCCCCC
RDYVPVSKR
CCCCCCCCC
>Mature Secondary Structure 
TEKSATVTLGEKQVELPVREGTIGPSVVDIATLYKHTGSFTYDPGFTSTASCESKITYI
CCCCCEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCEEEEE
DGDEGVLLHRGFPIEQLAEQGDFLETCYLLLYGELPTAAQKKDFDTRVTRHTMVHEQMSR
ECCCCEEEECCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
FFTGYRRDAHPMAVMCGTVGALSAFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYKYH
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHC
IGQPFVYPKNDLDYASNFLHMCFAVPCEDYKVDPVLARAMDRIFILHADHEQNASTSTVR
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCEEEEEECCCCCCCCCCEEE
LAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLNEIGSVDRIPEYIARAKDKNDPFR
EECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEE
LMGFGHRVYKNYDPRAKIMQKTMYEVLEATGNSDDPIMQVALELEKIALSDPYFVEKKLY
EEECCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEHHHCC
PNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEMIEDPQQRIGRPRQLYTGAGK
CCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEECCCCCC
RDYVPVSKR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8526514 [H]