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The map label for this gene is ppnK [H]

Identifier: 15888671

GI number: 15888671

Start: 1333726

End: 1334499

Strand: Reverse

Name: ppnK [H]

Synonym: Atu1345

Alternate gene names: 15888671

Gene position: 1334499-1333726 (Counterclockwise)

Preceding gene: 159184723

Following gene: 15888670

Centisome position: 46.96

GC content: 59.56

Gene sequence:

>774_bases
ATGTCGCATTCTACCTATTCACTGTCCTTCGTCGCCTCCCCATCCGAGGAGGCGCAGACGGCGTTGAAAGAGCTGAAAGC
CGTTTATAGCGATACACCGTTCGAAGAGGCCGATGTGATCGTTGCGCTTGGCGGCGACGGGTTCATGCTGCAAATCCTCA
ACGAAACGATGAATTCCGGCAAGCGTGTCTATGGCATGAACCGGGGGTCCGTCGGGTTCCTGATGAATGACTTCCGGGTG
GAAGGCCTCATCCAGCGCATCGCGGTGGCGAGCGGCAATGATTTCCATCCCCTGCGCATGACGACGACGGATTCCGATGG
CGACGAGTTTACCGCGCTCGCCATGAACGAAGTCAGCCTGTTTCGCCAGTCGCATCAGGCCGCCAAGCTGCGTGTCGAGG
TGGATGGCAAGGTGCGGCTGGAAGAGCTGATCTGCGACGGTATGATGGTGGCGACGCCAGCAGGGTCGACGGCCTACAAT
TTCTCCGCCCACGGGCCGATCCTGCCGCTGGAATCACCGCTTCTGGCGCTGACCCCGGTCAGCGCGTTCCGGCCGCGACG
CTGGCGCGGGGCGCTTCTGCCGAATAAGGTAACCGTCGATATTCATGTCCTGGAGCGCGACAAGCGGCCTGTGAATGCCG
TGGCCGATCACACCGAGGTGAAATCCGTTCGTCACGTCAGGATCGCACAATCACAGGACAGGACGGCGAAAATTCTCTCG
GATCCGGATCGTTCATGGTCGGACCGGGTTCTCGCTGAACAGTTCAACAATTAA

Upstream 100 bases:

>100_bases
TCCTCCTCTTGGTTGAGGTTTCAAGATTTCGAGCTGCTTCAACGGGTTACAGCATCCTGCGCGGACCGGTTCCGGTCTGC
GCCGTTGTCGAGGGAAGCGG

Downstream 100 bases:

>100_bases
ACCAACCACCACGATTGCCATGCACGTCAAAAAAACGCTCCTCGCTGCTCTGCTTCTTGCCACGACCGTCCTGCCCGCGC
GGGCGCAGACGCAGGCGATC

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSHSTYSLSFVASPSEEAQTALKELKAVYSDTPFEEADVIVALGGDGFMLQILNETMNSGKRVYGMNRGSVGFLMNDFRV
EGLIQRIAVASGNDFHPLRMTTTDSDGDEFTALAMNEVSLFRQSHQAAKLRVEVDGKVRLEELICDGMMVATPAGSTAYN
FSAHGPILPLESPLLALTPVSAFRPRRWRGALLPNKVTVDIHVLERDKRPVNAVADHTEVKSVRHVRIAQSQDRTAKILS
DPDRSWSDRVLAEQFNN

Sequences:

>Translated_257_residues
MSHSTYSLSFVASPSEEAQTALKELKAVYSDTPFEEADVIVALGGDGFMLQILNETMNSGKRVYGMNRGSVGFLMNDFRV
EGLIQRIAVASGNDFHPLRMTTTDSDGDEFTALAMNEVSLFRQSHQAAKLRVEVDGKVRLEELICDGMMVATPAGSTAYN
FSAHGPILPLESPLLALTPVSAFRPRRWRGALLPNKVTVDIHVLERDKRPVNAVADHTEVKSVRHVRIAQSQDRTAKILS
DPDRSWSDRVLAEQFNN
>Mature_256_residues
SHSTYSLSFVASPSEEAQTALKELKAVYSDTPFEEADVIVALGGDGFMLQILNETMNSGKRVYGMNRGSVGFLMNDFRVE
GLIQRIAVASGNDFHPLRMTTTDSDGDEFTALAMNEVSLFRQSHQAAKLRVEVDGKVRLEELICDGMMVATPAGSTAYNF
SAHGPILPLESPLLALTPVSAFRPRRWRGALLPNKVTVDIHVLERDKRPVNAVADHTEVKSVRHVRIAQSQDRTAKILSD
PDRSWSDRVLAEQFNN

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788968, Length=154, Percent_Identity=31.8181818181818, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6325068, Length=187, Percent_Identity=29.9465240641711, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 28403; Mature: 28271

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHSTYSLSFVASPSEEAQTALKELKAVYSDTPFEEADVIVALGGDGFMLQILNETMNSG
CCCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHHHHHHHHHCC
KRVYGMNRGSVGFLMNDFRVEGLIQRIAVASGNDFHPLRMTTTDSDGDEFTALAMNEVSL
CEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEHHHHHHH
FRQSHQAAKLRVEVDGKVRLEELICDGMMVATPAGSTAYNFSAHGPILPLESPLLALTPV
HHHCCCCEEEEEEECCCEEHHHHHHCCEEEECCCCCCEEECCCCCCCCCCCCCEEEECCH
SAFRPRRWRGALLPNKVTVDIHVLERDKRPVNAVADHTEVKSVRHVRIAQSQDRTAKILS
HHCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHC
DPDRSWSDRVLAEQFNN
CCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SHSTYSLSFVASPSEEAQTALKELKAVYSDTPFEEADVIVALGGDGFMLQILNETMNSG
CCCEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHHHHHHHHHCC
KRVYGMNRGSVGFLMNDFRVEGLIQRIAVASGNDFHPLRMTTTDSDGDEFTALAMNEVSL
CEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEHHHHHHH
FRQSHQAAKLRVEVDGKVRLEELICDGMMVATPAGSTAYNFSAHGPILPLESPLLALTPV
HHHCCCCEEEEEEECCCEEHHHHHHCCEEEECCCCCCEEECCCCCCCCCCCCCEEEECCH
SAFRPRRWRGALLPNKVTVDIHVLERDKRPVNAVADHTEVKSVRHVRIAQSQDRTAKILS
HHCCCCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCHHHHHC
DPDRSWSDRVLAEQFNN
CCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]