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The map label for this gene is acd [H]

Identifier: 15888635

GI number: 15888635

Start: 1302247

End: 1303899

Strand: Direct

Name: acd [H]

Synonym: Atu1310

Alternate gene names: 15888635

Gene position: 1302247-1303899 (Clockwise)

Preceding gene: 159184700

Following gene: 159184704

Centisome position: 45.83

GC content: 62.25

Gene sequence:

>1653_bases
ATGACCCAGAATTCCCGGACAGAAGAAACGCTCGCCGAACTGAACCAGCCTAGCCTCTGGTCCGGTATCAACGCCTATCG
TTCCGATCCGTTGATCGTCGATCTCACCTCCGGCCTGTCGCGCAATCTGAGGGACGAGTACGACCAGCTCGGCCGTTACG
TTACCTCGCATGAGGCGCAGGAACTGGCGCGGATGGCCAATCAGGGCGTGCCGCAGCTGCATACCCACGGCCCGCGCGGC
GAACGTCTCGACCAGGTGGAATTCCATCCCGCCTGGCATGCGCTGATGCGCCGTTCCATGTCATCAGGCCTGCATTCCAG
CGTCTGGGAGAATTCCCCCGATACGCGCGGGAGTGAGCATAAGGCCCGCGCCACGAAATTCTACCTCACCTCGCAGCTGG
AGGCAGGGCATCTCTGCCCGCTGACCATGACGAGCGCCTCGGTTGCCGCCATCATGACCTCGCCGCGGGTGCAGAAGGAG
TGGATGCCGAAGATCCTGTCGCGCAAATATGACAGCGCGCAGAAACCGGCCCTGCAAAAAACCGCCGTCACCGTTGGCAT
GGGCATGACGGAAAAGCAGGGCGGCACGGATGTACGTGCCAACCGCACCACGGCCGAGCGCGTGGGCGAGGGTATCTATC
GCCTCTCCGGCCACAAGTGGTTCCTTTCTGCGCCAATGAGCGACGGTTTCGTGATGCTCGCCCAGATGGGCGACGGCATG
GGCTGCTTCCTGGTGCCGCGTTATCTTGAAGACGGTTCGAAGAACGGCCTGCATTTCCAGCGTCTGAAAGACAAACTCGG
CAACCGCTCCAATGCGTCGGCCGAAGTCGAGTTCACCGATGCCTTCGGTTATCTGCTCGGCGATCCCGGCAGCGGTATCC
GCACCATCCTCGACATGGTGACGTTGACGCGGCTCGATTGTGCGCTGGCGTCTGCTGGCATGATGCGCGCCTCGCTTGCC
GAAGCCGTGCATTTTGCCCGCGGCCGCTCAGTGTTCGGAAAAATGCTGGTCAGCCAGCCGATCATGACTCGCGTTCTCGC
CGACATGGCGCTGGATGTGGCGGCTGCCACGGCGCTCTCTTTCCGGCTGGCAACGGCCTTCGACGCCGCCCGCAACAATC
CGGCAGAAGCCGCGTATGCGCGGGTCATGACGCCCATCGTCAAATACTGGTGCTGCAAGATCGCGCCAGCGCTTATCTAT
GAGGCCATGGAATGCCTTGGCGGCAACGGTTATGTGGAAGAGCGGCCGATTGCCCGTCACTACCGCGAAGCGCCGGTTAA
CGCCATCTGGGAAGGCTCCGGCAACGTCATGGCGCTGGATGTGCTGCGGGTTCTTCAGCGCGGCAAGGACCTGTTCGATC
TCGTCTTCCAGACGCTGGAGCGCGATCTCGGACCTGCCGGCAAGAAGACCACCGATGTGTTGCGCGCCGCGATCGCCCTT
GCAGAACGCGATGAAGGGGCGGCTCGCCTGCTGGTGGAGCAGTTCGCGCTTGCGGCCGCTGCCGCCGAGCTTTGCCGGCT
CGGTGCCGGCAAGATCGCCGATGCCTTCCTCGAAACCCGTCTCGCAGGTGGCTGGAGGCACACTTATGGCATGCTCGATT
CCCGCTTCGATCCGAATTATATAATCGATTTATTGTATCCGCCCGCATCCTGA

Upstream 100 bases:

>100_bases
TGAAAGCGGCGGCTTAATCGTCTCAATCGCTTCCTGTGGGCGGAATTATGCAATATCACCCCACTATGCAATGCCAGTAT
AAAACAGCTAGAAGCAGCGG

Downstream 100 bases:

>100_bases
CGGATAAAGGGTGGAGGGCTATTTTTTGCAGTCCCTGTGGGAGGGGTATCGGATTTGAGAAAATGCATTGGCGTGGGGAG
TATTCCTGTCTTTCAGACAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MTQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQELARMANQGVPQLHTHGPRG
ERLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEHKARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKE
WMPKILSRKYDSAQKPALQKTAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGM
GCFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMVTLTRLDCALASAGMMRASLA
EAVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALSFRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIY
EAMECLGGNGYVEERPIARHYREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIAL
AERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNYIIDLLYPPAS

Sequences:

>Translated_550_residues
MTQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQELARMANQGVPQLHTHGPRG
ERLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEHKARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKE
WMPKILSRKYDSAQKPALQKTAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGM
GCFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMVTLTRLDCALASAGMMRASLA
EAVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALSFRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIY
EAMECLGGNGYVEERPIARHYREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIAL
AERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNYIIDLLYPPAS
>Mature_549_residues
TQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQELARMANQGVPQLHTHGPRGE
RLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEHKARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKEW
MPKILSRKYDSAQKPALQKTAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGMG
CFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMVTLTRLDCALASAGMMRASLAE
AVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALSFRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIYE
AMECLGGNGYVEERPIARHYREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIALA
ERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNYIIDLLYPPAS

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=287, Percent_Identity=29.9651567944251, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI4501859, Length=279, Percent_Identity=26.1648745519713, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI4557231, Length=268, Percent_Identity=27.9850746268657, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI187960098, Length=268, Percent_Identity=27.9850746268657, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI226958412, Length=301, Percent_Identity=25.2491694352159, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI226958414, Length=301, Percent_Identity=25.2491694352159, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4501857, Length=276, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4557235, Length=391, Percent_Identity=25.5754475703325, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI76496475, Length=391, Percent_Identity=25.5754475703325, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7656849, Length=265, Percent_Identity=27.9245283018868, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI21361497, Length=271, Percent_Identity=23.6162361623616, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=515, Percent_Identity=43.6893203883495, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786223, Length=263, Percent_Identity=25.4752851711027, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081958, Length=285, Percent_Identity=23.859649122807, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI86563383, Length=497, Percent_Identity=31.3883299798793, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI86563381, Length=497, Percent_Identity=31.3883299798793, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17538396, Length=303, Percent_Identity=26.4026402640264, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=304, Percent_Identity=23.0263157894737, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=281, Percent_Identity=24.5551601423488, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=266, Percent_Identity=24.4360902255639, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=270, Percent_Identity=23.7037037037037, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=24.5353159851301, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=274, Percent_Identity=25.9124087591241, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=266, Percent_Identity=24.812030075188, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=295, Percent_Identity=26.4406779661017, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21355753, Length=294, Percent_Identity=24.8299319727891, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24646207, Length=265, Percent_Identity=27.1698113207547, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24660351, Length=327, Percent_Identity=25.0764525993884, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI281363737, Length=428, Percent_Identity=22.196261682243, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24666513, Length=265, Percent_Identity=21.5094339622642, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60414; Mature: 60283

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQ
CCCCCHHHHHHHHCCCCCHHHCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
ELARMANQGVPQLHTHGPRGERLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCH
KARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKEWMPKILSRKYDSAQKPALQK
HHHHHHEEEECCCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
TAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGM
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHCHHEEECCCEEEEECCCCCCEEEEEECCCCC
GCFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMV
CCEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHH
TLTRLDCALASAGMMRASLAEAVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIYEAMECLGGNGYVEERPIARH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
YREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIAL
HHHCCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNY
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
IIDLLYPPAS
EEEEECCCCC
>Mature Secondary Structure 
TQNSRTEETLAELNQPSLWSGINAYRSDPLIVDLTSGLSRNLRDEYDQLGRYVTSHEAQ
CCCCHHHHHHHHCCCCCHHHCCHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
ELARMANQGVPQLHTHGPRGERLDQVEFHPAWHALMRRSMSSGLHSSVWENSPDTRGSEH
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCH
KARATKFYLTSQLEAGHLCPLTMTSASVAAIMTSPRVQKEWMPKILSRKYDSAQKPALQK
HHHHHHEEEECCCCCCCCCCEEECHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
TAVTVGMGMTEKQGGTDVRANRTTAERVGEGIYRLSGHKWFLSAPMSDGFVMLAQMGDGM
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHCHHEEECCCEEEEECCCCCCEEEEEECCCCC
GCFLVPRYLEDGSKNGLHFQRLKDKLGNRSNASAEVEFTDAFGYLLGDPGSGIRTILDMV
CCEEEHHHHCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHHH
TLTRLDCALASAGMMRASLAEAVHFARGRSVFGKMLVSQPIMTRVLADMALDVAAATALS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRLATAFDAARNNPAEAAYARVMTPIVKYWCCKIAPALIYEAMECLGGNGYVEERPIARH
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
YREAPVNAIWEGSGNVMALDVLRVLQRGKDLFDLVFQTLERDLGPAGKKTTDVLRAAIAL
HHHCCCCEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
AERDEGAARLLVEQFALAAAAAELCRLGAGKIADAFLETRLAGGWRHTYGMLDSRFDPNY
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
IIDLLYPPAS
EEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]