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The map label for this gene is rnr [H]

Identifier: 15888628

GI number: 15888628

Start: 1291692

End: 1294046

Strand: Reverse

Name: rnr [H]

Synonym: Atu1303

Alternate gene names: 15888628

Gene position: 1294046-1291692 (Counterclockwise)

Preceding gene: 15888629

Following gene: 15888627

Centisome position: 45.54

GC content: 62.89

Gene sequence:

>2355_bases
GTGAGCAAGGCGCCACGTCAGAGACAGGGTTCCGCCAGTGACGGTTTCGGACGCACCGGGCGCGGCAAGCGGGTGAGCGA
AGGTGAAGGCATCATCCATGGCGAGGTGCCTTCCCGCGAAGTGCTGCTGAAATTCATCGCGGACCATCCGCAGCAGGCCT
CCAAGCGCGAAATCGCCAAGGCTTTCGGGCTGAAGGGCGAAAACCGCATCGTTCTGAAAGCCCTGCTGAAGGAACTCGAA
GTCGATGGCATGGTGCACAAGAGCCGAAAGTCGCTGACGCGGCCGGGCGGCCTGCCGCCCGTGACGGTTCTCGACATCAC
CACCCGTGACAAGGACGGCGAGTTGATCGGCCGCCCGGCGGAATGGCCGGAGGATATGGGCGCGGCACCGGCCGTGCTGA
TCCGCCAGTCTTCGCAGGATCGCGGCAAGAAGGCTCCCGCCGCCGGTCTCGGTGACCGCATTCTGGCTAAGATTTTCCCT
TCCAAGGACACCGTTGGCCCGGCCTATACGGCCCGTGTCGTGAAACTGATCGACCGTCGCCAGAACGCGCTGCTCGGCGT
GTTCAAGCAGACGGAAGGCGGCGGCGGACGGCTGATGCCGATCGACCGGCGCGGCGAAGAAATGGTCATCGATCCCGATG
GCGTCGGCGATGCCAAGGACGGCGATCTGATCGAGGTGGAAACCTCGCGCAATAGCGGCCGTTACGGCCTGACGCGGGCA
AAGGTTCTGTCCGTCGTCGGTTCGGTCGCCTCGGAAAAGGCGATCTCGATGATCGCCATTTATGCGCATGGCATTCCGCA
TATCTTCCCGCCAAATGTCTTGGCGGAAGCGGATGCGGCCAAGGCCGCGACCATGTCGCACCGCGAGGACTGGCGCGACC
TGCCGCTCATCACCATCGATCCGGCCGACGCCAAGGACCATGACGATGCGGTCTATGCCGAACTGGACCCCTCGCCCGAC
AATCCTGACGGTGTCATCGTCACCGTCGCCATTGCCGATGTCTCCTGGTATGTGCGGCCGGGCGCGCCACTCGACCGCGA
GGCGCTGAAGCGTGGCAACTCGGTCTATTTCCCCGACCGTGTCGTGCCGATGCTGCCGGAACGCATCTCCAATGATCTCT
GCTCGCTGAAGGAAGGCGTCGACCGTCCTGCCCTTGCCGTGCGGATGACGTTCTCGAAGGAAGGCCGCAAGGCGAGCCAC
ACTTTCCATCGCATCATGATGAAAAGTGCCGCCAAGCTCTCCTACCAGCAGGCGCAGGCGGCGATCGACGGCAACCCTGA
CGACAAGACCGGCACGCTGCTGGAGCCGATCCTCAAGCCGCTGTGGCATGCCTATGAAGTGATGAAACGCGGCCGCGACC
GCCGCCAGCCGCTGGAACTCGACATGCCGGAGCGCAAGATCCAGCTGCGGCCCGATGGCACGGTGGACAAGGTCGTCATT
CCCGAACGCCTCGATGCGCATAAGCTGATCGAGGAAATGATGATCCAGGCGAATGTTGCCGCCGCCGAAACGCTGGAAAC
GAAAAAGCAGCGGCTGGTCTACCGCGTGCACGACGCCCCGACGCTCTCCAAGCAGGAGGTGCTGCGCGAATTCCTTGGCA
CCATCGGCATTTCCATGGCCAAGGGTGTGGCAATGCGCGCCAATTCCTTCAACGGCATTCTGGCACGCGCGCTCGACACG
CCGCACCAGATCATGGTCAACGAGATGGTGCTGCGCAGCCAGAGTCAGGCGATTTACAGCCCGGAAAATATCGGCCATTT
CGGCCTCAACCTGATGAAATACGCGCATTTCACCTCGCCGATCCGCCGTTATGCCGATCTGATCGTGCATCGCGCACTGG
TGGGCTCGCTGGGGCTAGGCGAAGGCGGCATCACGCCGCAGGAAGAGGCCACGCTGGACGATATCGCCGCGGAAATCTCG
ACCTTCGAGCGCCGCGCCATGGCGGCCGAGCGCGATACCGTCAATCGGCTGATTGCGCATCATCTGTCGGAACGTGTGGG
CGAGGAATTCGAGGGCCGCGTCGGCGGTGTCACCAAGGCGGGACTATTTGTCGCGCTGCCGCAGTTTGGCGCTGATGGAT
TTGTTCCTATATCTACACTCGGAACCGATTATTTCTTCTATGATGAAGCCCATCAGGCTCTGACGGGGGAAAAGACCGGT
CTCGGTTATCAGCTTGGCGACACGGTTCAGGTACGGCTTGCGGAAGCGGTGCCTCTTGCAGGCGCATTGCGTTTTGAAAT
GCTGAGCCCGGGGCGTAAGATGCCGGTCGGCTCGCGGTCGTTCCACAAGGCGGGCCGGCGGACATCGCGTCCTGGCGCGA
AGCCCGGGACGCGGCCGCCGAGAGGACGACGCTAA

Upstream 100 bases:

>100_bases
AGGCAGCGGCAAAGCCGAAAGCCACCAAGGCCAAGGCGGCAACCAAGAGCAAGGCGGCCGCCAAGCCGAAGGCAGCGGCC
AAAACCAAGAAGGCAGCAGA

Downstream 100 bases:

>100_bases
CAAGACCGCGAAGCGGTTCAAGAACGGGAGAAGGACTTAAGGATGAGTGCACATCAGGGCTCGGAAACGGTCACCTTCGG
AGACAGCAGCGCGGAGAGGC

Product: exoribonuclease

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MSKAPRQRQGSASDGFGRTGRGKRVSEGEGIIHGEVPSREVLLKFIADHPQQASKREIAKAFGLKGENRIVLKALLKELE
VDGMVHKSRKSLTRPGGLPPVTVLDITTRDKDGELIGRPAEWPEDMGAAPAVLIRQSSQDRGKKAPAAGLGDRILAKIFP
SKDTVGPAYTARVVKLIDRRQNALLGVFKQTEGGGGRLMPIDRRGEEMVIDPDGVGDAKDGDLIEVETSRNSGRYGLTRA
KVLSVVGSVASEKAISMIAIYAHGIPHIFPPNVLAEADAAKAATMSHREDWRDLPLITIDPADAKDHDDAVYAELDPSPD
NPDGVIVTVAIADVSWYVRPGAPLDREALKRGNSVYFPDRVVPMLPERISNDLCSLKEGVDRPALAVRMTFSKEGRKASH
TFHRIMMKSAAKLSYQQAQAAIDGNPDDKTGTLLEPILKPLWHAYEVMKRGRDRRQPLELDMPERKIQLRPDGTVDKVVI
PERLDAHKLIEEMMIQANVAAAETLETKKQRLVYRVHDAPTLSKQEVLREFLGTIGISMAKGVAMRANSFNGILARALDT
PHQIMVNEMVLRSQSQAIYSPENIGHFGLNLMKYAHFTSPIRRYADLIVHRALVGSLGLGEGGITPQEEATLDDIAAEIS
TFERRAMAAERDTVNRLIAHHLSERVGEEFEGRVGGVTKAGLFVALPQFGADGFVPISTLGTDYFFYDEAHQALTGEKTG
LGYQLGDTVQVRLAEAVPLAGALRFEMLSPGRKMPVGSRSFHKAGRRTSRPGAKPGTRPPRGRR

Sequences:

>Translated_784_residues
MSKAPRQRQGSASDGFGRTGRGKRVSEGEGIIHGEVPSREVLLKFIADHPQQASKREIAKAFGLKGENRIVLKALLKELE
VDGMVHKSRKSLTRPGGLPPVTVLDITTRDKDGELIGRPAEWPEDMGAAPAVLIRQSSQDRGKKAPAAGLGDRILAKIFP
SKDTVGPAYTARVVKLIDRRQNALLGVFKQTEGGGGRLMPIDRRGEEMVIDPDGVGDAKDGDLIEVETSRNSGRYGLTRA
KVLSVVGSVASEKAISMIAIYAHGIPHIFPPNVLAEADAAKAATMSHREDWRDLPLITIDPADAKDHDDAVYAELDPSPD
NPDGVIVTVAIADVSWYVRPGAPLDREALKRGNSVYFPDRVVPMLPERISNDLCSLKEGVDRPALAVRMTFSKEGRKASH
TFHRIMMKSAAKLSYQQAQAAIDGNPDDKTGTLLEPILKPLWHAYEVMKRGRDRRQPLELDMPERKIQLRPDGTVDKVVI
PERLDAHKLIEEMMIQANVAAAETLETKKQRLVYRVHDAPTLSKQEVLREFLGTIGISMAKGVAMRANSFNGILARALDT
PHQIMVNEMVLRSQSQAIYSPENIGHFGLNLMKYAHFTSPIRRYADLIVHRALVGSLGLGEGGITPQEEATLDDIAAEIS
TFERRAMAAERDTVNRLIAHHLSERVGEEFEGRVGGVTKAGLFVALPQFGADGFVPISTLGTDYFFYDEAHQALTGEKTG
LGYQLGDTVQVRLAEAVPLAGALRFEMLSPGRKMPVGSRSFHKAGRRTSRPGAKPGTRPPRGRR
>Mature_783_residues
SKAPRQRQGSASDGFGRTGRGKRVSEGEGIIHGEVPSREVLLKFIADHPQQASKREIAKAFGLKGENRIVLKALLKELEV
DGMVHKSRKSLTRPGGLPPVTVLDITTRDKDGELIGRPAEWPEDMGAAPAVLIRQSSQDRGKKAPAAGLGDRILAKIFPS
KDTVGPAYTARVVKLIDRRQNALLGVFKQTEGGGGRLMPIDRRGEEMVIDPDGVGDAKDGDLIEVETSRNSGRYGLTRAK
VLSVVGSVASEKAISMIAIYAHGIPHIFPPNVLAEADAAKAATMSHREDWRDLPLITIDPADAKDHDDAVYAELDPSPDN
PDGVIVTVAIADVSWYVRPGAPLDREALKRGNSVYFPDRVVPMLPERISNDLCSLKEGVDRPALAVRMTFSKEGRKASHT
FHRIMMKSAAKLSYQQAQAAIDGNPDDKTGTLLEPILKPLWHAYEVMKRGRDRRQPLELDMPERKIQLRPDGTVDKVVIP
ERLDAHKLIEEMMIQANVAAAETLETKKQRLVYRVHDAPTLSKQEVLREFLGTIGISMAKGVAMRANSFNGILARALDTP
HQIMVNEMVLRSQSQAIYSPENIGHFGLNLMKYAHFTSPIRRYADLIVHRALVGSLGLGEGGITPQEEATLDDIAAEIST
FERRAMAAERDTVNRLIAHHLSERVGEEFEGRVGGVTKAGLFVALPQFGADGFVPISTLGTDYFFYDEAHQALTGEKTGL
GYQLGDTVQVRLAEAVPLAGALRFEMLSPGRKMPVGSRSFHKAGRRTSRPGAKPGTRPPRGRR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=597, Percent_Identity=26.6331658291457, Blast_Score=170, Evalue=5e-42,
Organism=Homo sapiens, GI190014623, Length=597, Percent_Identity=26.6331658291457, Blast_Score=169, Evalue=7e-42,
Organism=Homo sapiens, GI134288890, Length=490, Percent_Identity=28.5714285714286, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI219521928, Length=448, Percent_Identity=28.7946428571429, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI19115966, Length=448, Percent_Identity=28.7946428571429, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI156105695, Length=142, Percent_Identity=35.9154929577465, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI156105693, Length=142, Percent_Identity=35.9154929577465, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87082383, Length=736, Percent_Identity=35.054347826087, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1787542, Length=463, Percent_Identity=31.317494600432, Blast_Score=170, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=558, Percent_Identity=28.673835125448, Blast_Score=182, Evalue=8e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=413, Percent_Identity=30.7506053268765, Blast_Score=161, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=449, Percent_Identity=30.7349665924276, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320499, Length=388, Percent_Identity=24.4845360824742, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649634, Length=672, Percent_Identity=26.4880952380952, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19922976, Length=412, Percent_Identity=27.1844660194175, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24654597, Length=412, Percent_Identity=27.1844660194175, Blast_Score=116, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24654592, Length=399, Percent_Identity=27.3182957393484, Blast_Score=116, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 85790; Mature: 85659

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAPRQRQGSASDGFGRTGRGKRVSEGEGIIHGEVPSREVLLKFIADHPQQASKREIAK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHH
AFGLKGENRIVLKALLKELEVDGMVHKSRKSLTRPGGLPPVTVLDITTRDKDGELIGRPA
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEECCCC
EWPEDMGAAPAVLIRQSSQDRGKKAPAAGLGDRILAKIFPSKDTVGPAYTARVVKLIDRR
CCCHHCCCCCEEEEECCCHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QNALLGVFKQTEGGGGRLMPIDRRGEEMVIDPDGVGDAKDGDLIEVETSRNSGRYGLTRA
HHHHEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHH
KVLSVVGSVASEKAISMIAIYAHGIPHIFPPNVLAEADAAKAATMSHREDWRDLPLITID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCEEEEC
PADAKDHDDAVYAELDPSPDNPDGVIVTVAIADVSWYVRPGAPLDREALKRGNSVYFPDR
CCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECEEEEECCCCCCCHHHHHCCCCEECCCC
VVPMLPERISNDLCSLKEGVDRPALAVRMTFSKEGRKASHTFHRIMMKSAAKLSYQQAQA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIDGNPDDKTGTLLEPILKPLWHAYEVMKRGRDRRQPLELDMPERKIQLRPDGTVDKVVI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEC
PERLDAHKLIEEMMIQANVAAAETLETKKQRLVYRVHDAPTLSKQEVLREFLGTIGISMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KGVAMRANSFNGILARALDTPHQIMVNEMVLRSQSQAIYSPENIGHFGLNLMKYAHFTSP
CCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IRRYADLIVHRALVGSLGLGEGGITPQEEATLDDIAAEISTFERRAMAAERDTVNRLIAH
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSERVGEEFEGRVGGVTKAGLFVALPQFGADGFVPISTLGTDYFFYDEAHQALTGEKTG
HHHHHHCHHHCCCCCCEECCCCEEEECCCCCCCCEEHHHCCCCEEEECHHHHHHCCCCCC
LGYQLGDTVQVRLAEAVPLAGALRFEMLSPGRKMPVGSRSFHKAGRRTSRPGAKPGTRPP
CCEECCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
RGRR
CCCC
>Mature Secondary Structure 
SKAPRQRQGSASDGFGRTGRGKRVSEGEGIIHGEVPSREVLLKFIADHPQQASKREIAK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHCCCCHHHHHHHHH
AFGLKGENRIVLKALLKELEVDGMVHKSRKSLTRPGGLPPVTVLDITTRDKDGELIGRPA
HHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCEECCCC
EWPEDMGAAPAVLIRQSSQDRGKKAPAAGLGDRILAKIFPSKDTVGPAYTARVVKLIDRR
CCCHHCCCCCEEEEECCCHHCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QNALLGVFKQTEGGGGRLMPIDRRGEEMVIDPDGVGDAKDGDLIEVETSRNSGRYGLTRA
HHHHEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCHHHH
KVLSVVGSVASEKAISMIAIYAHGIPHIFPPNVLAEADAAKAATMSHREDWRDLPLITID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCEEEEC
PADAKDHDDAVYAELDPSPDNPDGVIVTVAIADVSWYVRPGAPLDREALKRGNSVYFPDR
CCCCCCCCCEEEEEECCCCCCCCCEEEEEEEECEEEEECCCCCCCHHHHHCCCCEECCCC
VVPMLPERISNDLCSLKEGVDRPALAVRMTFSKEGRKASHTFHRIMMKSAAKLSYQQAQA
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AIDGNPDDKTGTLLEPILKPLWHAYEVMKRGRDRRQPLELDMPERKIQLRPDGTVDKVVI
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCEEEC
PERLDAHKLIEEMMIQANVAAAETLETKKQRLVYRVHDAPTLSKQEVLREFLGTIGISMA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KGVAMRANSFNGILARALDTPHQIMVNEMVLRSQSQAIYSPENIGHFGLNLMKYAHFTSP
CCCEEECCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
IRRYADLIVHRALVGSLGLGEGGITPQEEATLDDIAAEISTFERRAMAAERDTVNRLIAH
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLSERVGEEFEGRVGGVTKAGLFVALPQFGADGFVPISTLGTDYFFYDEAHQALTGEKTG
HHHHHHCHHHCCCCCCEECCCCEEEECCCCCCCCEEHHHCCCCEEEECHHHHHHCCCCCC
LGYQLGDTVQVRLAEAVPLAGALRFEMLSPGRKMPVGSRSFHKAGRRTSRPGAKPGTRPP
CCEECCCEEEEEEHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCC
RGRR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]