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The map label for this gene is lolC [H]

Identifier: 15888617

GI number: 15888617

Start: 1277188

End: 1278495

Strand: Direct

Name: lolC [H]

Synonym: Atu1289

Alternate gene names: 15888617

Gene position: 1277188-1278495 (Clockwise)

Preceding gene: 159184694

Following gene: 159184695

Centisome position: 44.95

GC content: 59.02

Gene sequence:

>1308_bases
ATGGCAAAAGCCGATGCTGACAAGGGTGCGGCTCCTTCCGCCCGGGAAAGGACCGCCCGGCCTTTTTCCGCTTTTGAACG
CATGGTGGCCTGGCGTTATCTGCGGTCGCGGCGCAAGGAAGCCTTCATTTCCGTCATCGCCGGTTTTTCTTTCGTCGGCA
TCATGCTGGGTGTGGCGACGCTGATCATCGTCATGGCTGTCATGAACGGTTTCCGCACCGAACTGATTTCCCGCATTCTC
GGCATTAACGGTCACATGATCGTGCAGCCGATCGATCAACCGTTTAACAATTACGATGAACTGGCGAAGAAGTTTTCAGC
CGTGCCGGGTGTCACCATGGCCTTGCCGCTGGTGGAGGGCCAGACGCTTGCCTCCGGCCGTGGCGGTGCAGGCTCCGGCG
CGCTGGTGCGTGGTGTGCGCCAGGAGGACATCGACAAGATCAAGGAAGTCGCCACCAACATCAAGACCGGCGATCTCGTC
GGCTTCATGGCAGGTGACGGCGTTCTCGTCGGTTCACGGCTCGCCTCCCAACTGGGCGTGACGGCGGGCGACGATATCAC
CCTCATTTCGCCGGAAGGCGACGTGACGCCCATGGGCATCAATCCACGTGTTAAATCCTACAAGATATCAGGCGTCTTCG
AGATCGGCATGTCGGAATATGACGCATCGATGATCTATATGCCGCTGTCCGAGGCGCAGCTTTATTTCAATGCCAACGGC
ATTGTGCAATCCATCGAGCTTTACGTCAGCCGGCCTGATGATGTCGACGGCATCCGACCGCTGGTGGAGCAGGCCGCCGA
ACGGCAGATCTATATCACCGACTGGCGACAGCGGAACCAGACCTTCTTCTCCGCTCTGCAGGTGGAACGGAACGTGATGT
TCATGATCCTCACCCTCATCGTTCTGGTGGCGGCGCTCAACATCATCTCCGGCCTCATCATGCTGGTGAAGGACAAGGGC
AGCGATATCGCCATCCTTCGCACCATGGGCGCAAGCTCGGGCGCGGTGATGCGCATCTTCTTCATGACCGGGGCCGCCAT
CGGCACCGTCGGCACCTTTGCCGGCGTCGCACTCGGCGTCCTTGTCTGCCTCAACGTGGAATCCATCCGACAGTTCTTCT
CCTGGGTATCGGGCACGGTGCTGTTTGATCCGCAGCTCTATTTCCTGAGCCAGCTTCCCGCCGAAATGGATTTGAGCGAG
ACCATCACCGTCGTCATCATGGCGCTGACGCTTTCTTTCCTGGCAACGATCTTTCCGGCCTGGCGGGCTTCCAAGCTCGA
TCCGGTGCAGGCCCTGCGTTACGAATAA

Upstream 100 bases:

>100_bases
TCATGCGAAGACCGCTCCGGTTTTATGGCGCAGGCGCTGCTACGATTGGGACCGATCTTTGGAAAAGACCGATCCTGCAA
ATTGAGATCAGGGAGACGAC

Downstream 100 bases:

>100_bases
GGACCGCTTCGCAATATGGCAAAAAAAACAGTGCTGCGGCTTACCGGTGTCGAGAGAACCTATGGTCAGGGCGAGACATC
GCTTTCAATTTTGCGCAAGG

Product: ABC transporter, membrane spanning protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAKADADKGAAPSARERTARPFSAFERMVAWRYLRSRRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELISRIL
GINGHMIVQPIDQPFNNYDELAKKFSAVPGVTMALPLVEGQTLASGRGGAGSGALVRGVRQEDIDKIKEVATNIKTGDLV
GFMAGDGVLVGSRLASQLGVTAGDDITLISPEGDVTPMGINPRVKSYKISGVFEIGMSEYDASMIYMPLSEAQLYFNANG
IVQSIELYVSRPDDVDGIRPLVEQAAERQIYITDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKG
SDIAILRTMGASSGAVMRIFFMTGAAIGTVGTFAGVALGVLVCLNVESIRQFFSWVSGTVLFDPQLYFLSQLPAEMDLSE
TITVVIMALTLSFLATIFPAWRASKLDPVQALRYE

Sequences:

>Translated_435_residues
MAKADADKGAAPSARERTARPFSAFERMVAWRYLRSRRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELISRIL
GINGHMIVQPIDQPFNNYDELAKKFSAVPGVTMALPLVEGQTLASGRGGAGSGALVRGVRQEDIDKIKEVATNIKTGDLV
GFMAGDGVLVGSRLASQLGVTAGDDITLISPEGDVTPMGINPRVKSYKISGVFEIGMSEYDASMIYMPLSEAQLYFNANG
IVQSIELYVSRPDDVDGIRPLVEQAAERQIYITDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKG
SDIAILRTMGASSGAVMRIFFMTGAAIGTVGTFAGVALGVLVCLNVESIRQFFSWVSGTVLFDPQLYFLSQLPAEMDLSE
TITVVIMALTLSFLATIFPAWRASKLDPVQALRYE
>Mature_434_residues
AKADADKGAAPSARERTARPFSAFERMVAWRYLRSRRKEAFISVIAGFSFVGIMLGVATLIIVMAVMNGFRTELISRILG
INGHMIVQPIDQPFNNYDELAKKFSAVPGVTMALPLVEGQTLASGRGGAGSGALVRGVRQEDIDKIKEVATNIKTGDLVG
FMAGDGVLVGSRLASQLGVTAGDDITLISPEGDVTPMGINPRVKSYKISGVFEIGMSEYDASMIYMPLSEAQLYFNANGI
VQSIELYVSRPDDVDGIRPLVEQAAERQIYITDWRQRNQTFFSALQVERNVMFMILTLIVLVAALNIISGLIMLVKDKGS
DIAILRTMGASSGAVMRIFFMTGAAIGTVGTFAGVALGVLVCLNVESIRQFFSWVSGTVLFDPQLYFLSQLPAEMDLSET
ITVVIMALTLSFLATIFPAWRASKLDPVQALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=410, Percent_Identity=31.7073170731707, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1787360, Length=418, Percent_Identity=30.622009569378, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 47242; Mature: 47111

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKADADKGAAPSARERTARPFSAFERMVAWRYLRSRRKEAFISVIAGFSFVGIMLGVAT
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIVMAVMNGFRTELISRILGINGHMIVQPIDQPFNNYDELAKKFSAVPGVTMALPLVEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
QTLASGRGGAGSGALVRGVRQEDIDKIKEVATNIKTGDLVGFMAGDGVLVGSRLASQLGV
CEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHHHHHHCC
TAGDDITLISPEGDVTPMGINPRVKSYKISGVFEIGMSEYDASMIYMPLSEAQLYFNANG
CCCCCEEEECCCCCEECCCCCCCCCEEEECEEEEECCCCCCCEEEEEECCCCEEEECCCC
IVQSIELYVSRPDDVDGIRPLVEQAAERQIYITDWRQRNQTFFSALQVERNVMFMILTLI
HHEEHHHEEECCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVAALNIISGLIMLVKDKGSDIAILRTMGASSGAVMRIFFMTGAAIGTVGTFAGVALGV
HHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHEEHHHHHCHHHHHHHHHHHHHHHH
LVCLNVESIRQFFSWVSGTVLFDPQLYFLSQLPAEMDLSETITVVIMALTLSFLATIFPA
HHHCCHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WRASKLDPVQALRYE
HCCCCCCHHHHHCCC
>Mature Secondary Structure 
AKADADKGAAPSARERTARPFSAFERMVAWRYLRSRRKEAFISVIAGFSFVGIMLGVAT
CCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIIVMAVMNGFRTELISRILGINGHMIVQPIDQPFNNYDELAKKFSAVPGVTMALPLVEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
QTLASGRGGAGSGALVRGVRQEDIDKIKEVATNIKTGDLVGFMAGDGVLVGSRLASQLGV
CEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEEHHHHHHHHCC
TAGDDITLISPEGDVTPMGINPRVKSYKISGVFEIGMSEYDASMIYMPLSEAQLYFNANG
CCCCCEEEECCCCCEECCCCCCCCCEEEECEEEEECCCCCCCEEEEEECCCCEEEECCCC
IVQSIELYVSRPDDVDGIRPLVEQAAERQIYITDWRQRNQTFFSALQVERNVMFMILTLI
HHEEHHHEEECCCCCCHHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVAALNIISGLIMLVKDKGSDIAILRTMGASSGAVMRIFFMTGAAIGTVGTFAGVALGV
HHHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCHHEEHHHHHCHHHHHHHHHHHHHHHH
LVCLNVESIRQFFSWVSGTVLFDPQLYFLSQLPAEMDLSETITVVIMALTLSFLATIFPA
HHHCCHHHHHHHHHHHCCCEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
WRASKLDPVQALRYE
HCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]