Click here to switch to the map view.

The map label for this gene is strB [H]

Identifier: 15888574

GI number: 15888574

Start: 1233104

End: 1233949

Strand: Reverse

Name: strB [H]

Synonym: Atu1243

Alternate gene names: 15888574

Gene position: 1233949-1233104 (Counterclockwise)

Preceding gene: 159184681

Following gene: 159184680

Centisome position: 43.42

GC content: 58.98

Gene sequence:

>846_bases
ATGATCAGCAATACGCCGTCTTTTCCGGCCTCGTGGAATATCGAGGCCGCAAAACGCATCGCCGATACACCGGCCGGCAT
CGTTTACGAACTGACGCGCAAGGACGGCTCCCTTGCCATTGCCAAGGTTCTGAAAAAGAAGGTGCTGAAAGACAGCCTTC
GCGGCGCGGATTTCATCGCATGGCGCGCGGGTATCGGTTGCGTCGAACTGCTCGACCAGTCCGACAATATTCTGTTGATG
GAACATGCCGGCACTGAGACCCTTCGCGACGTGCTGTTCCGCGATGGCAACGACGATGCCACCACGGAAATCGCCGCCGA
GGTTCTGCTTCGATATCACCAGCCATCAGAGCAGTCGCCGCCGTCCAGCCTGCTGACGCTGCCGCTCTATTTCGAAAGCC
TGTTCCGCAAGGCCGAACAGGATCGTTCCGACGGCGTCGACAGCCCCTTTGTCGAGGCAGCAAGGCTTGCGCAGACGCTG
ATTGACCAACAGCGGGATATCAAGCCGCTGCATGGCGACCTGCACCATGAGAATATCATGCACAGCGATCGCGGCTGGAT
CATCATCGATCCGGCCGGCCTGATCGGCGATGCGGCGCTTGATGTCGCCAACATGTTCTCCAATCCGCTCGACCGTTTCG
ACCTCACCCGCAGCGAAGCCCGCATCGCCTCCATGGCAGCGATCTTTTCAAGGGCGCTGCAACGGGACGAACGGCTATTG
CTGCAATATGCCTTCGCCTATGGCTGCCTTTCGGCCACGTGGCACGAAGAGGACGGCAATGCGGAAGAACGCGACAACGA
ACTCGCCGTCGCGGCAACCATCAAGGCAGTCCTGAAACATTTTTGA

Upstream 100 bases:

>100_bases
CGCCGGGCGGTGAGCATATCAATCTCGTGGCGCTGCTCGACAATCTCGGCAAGGGTGCCTCCGGCGCTGCGGTACAGAAC
ATGGAGTTGATGCTCTCGGC

Downstream 100 bases:

>100_bases
GCGGGGTCAGTCCCTGACTTCGACAGCAACGGGCGCCGGATATTCACCGATGAAACCGCGCCAATGGGCGACCGAAAAGC
CGAGCAGGATCAGTGCCATG

Product: streptomycin resistance protein

Products: NA

Alternate protein names: Streptomycin 3''-phosphotransferase; SPH [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIAWRAGIGCVELLDQSDNILLM
EHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSPPSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTL
IDQQRDIKPLHGDLHHENIMHSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF

Sequences:

>Translated_281_residues
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIAWRAGIGCVELLDQSDNILLM
EHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSPPSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTL
IDQQRDIKPLHGDLHHENIMHSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF
>Mature_281_residues
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIAWRAGIGCVELLDQSDNILLM
EHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSPPSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTL
IDQQRDIKPLHGDLHHENIMHSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF

Specific function: The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: =2.7.1.87 [H]

Molecular weight: Translated: 31243; Mature: 31243

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIA
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
WRAGIGCVELLDQSDNILLMEHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSP
HHHCCHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
PSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTLIDQQRDIKPLHGDLHHENIM
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
CCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF
HHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MISNTPSFPASWNIEAAKRIADTPAGIVYELTRKDGSLAIAKVLKKKVLKDSLRGADFIA
CCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHH
WRAGIGCVELLDQSDNILLMEHAGTETLRDVLFRDGNDDATTEIAAEVLLRYHQPSEQSP
HHHCCHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
PSSLLTLPLYFESLFRKAEQDRSDGVDSPFVEAARLAQTLIDQQRDIKPLHGDLHHENIM
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
HSDRGWIIIDPAGLIGDAALDVANMFSNPLDRFDLTRSEARIASMAAIFSRALQRDERLL
CCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LQYAFAYGCLSATWHEEDGNAEERDNELAVAATIKAVLKHF
HHHHHHHHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3889831 [H]