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The map label for this gene is corA [H]

Identifier: 15888054

GI number: 15888054

Start: 710699

End: 711727

Strand: Direct

Name: corA [H]

Synonym: Atu0710

Alternate gene names: 15888054

Gene position: 710699-711727 (Clockwise)

Preceding gene: 159184430

Following gene: 15888055

Centisome position: 25.01

GC content: 57.14

Gene sequence:

>1029_bases
ATGTTAAGCAGCATTGCGGCTGATGCCTGCGATGTGGAGCGGAGAAACGGATTGATAAAAGCCTATCGCGCCAATTGCGA
GGCGATCAGCCTGTCGACAGACGACGGCTCCGGACCGATTCCCGACGACATCGTCTGGATCGATCTCGTCAATCCCGACA
GGGCGGAAGAGCAGCGTGTGGAAAAGCTGCTGGGCGTTGAACTGCCGACGCGCGAAGACCTCAAGGATATCGAGCCTTCC
AGCCGCCTCTATATGGAAGACGGCAATGTCTTCATGACCGCTTCTCTGGTGTGGAAGGCGGATTCGGACGATCCGCGCCT
GACCGATATCGCCTTCATTCTGATCGGCAAGCGTCTGGTGACGATCCGTTATGCCGAGCCGAAATCATTCCATCTTTTCA
TCGCCGCCATCACCCGCGCGCCGCACGAGATGCGCAGCGGCACGGCGCTGCTGTTGAAACTGCTGGAAACCATCGTCGAC
CGGACCGCGGAAATTCTCGAAAATTCAGTTACGGGCATCGACAATCTCGCCGCCGACATTCTCGGCAGTCAGGCGCGCAG
CAAGCGCAAGGCACCCCGTTATCTCGAAGATCGCCTGACCAACATCGCCGCCTATCACCGGCTGATCTCGAAGCTTCGCG
TCAGCCTCGCATCGCTGGCGCGGCTGCAGACCTTCCTGTCCACCAGCGACCAAGCGCGCGAGGACAAGGGGGCAAAGGAA
CAGGGTAAGTCTGTCGGGCGCGATATACAATCGCTGAACGAACATGCCTCCTTCGTTTCCGGCAATCTGACATTTCTGCT
CGACGCCTCTCTCGGCATCATCAACATCGAGCAGAACGGCATCATCAAGATTTTCTCGATCGCTTCGGTGGTGTTTTTGC
CGCCAACGTTGGTGGCTTCGGTTTATGGAATGAACTTTCAGCTCATGCCGGAGTTGAACTGGACATTTGGTTATCCCCTT
GCGCTGGTCGTCATGCTGATGTCCGCCATCATCCCGTTTCTCTTTTTCCGCTGGAAGGGCTGGCTCTGA

Upstream 100 bases:

>100_bases
GTTTGGCTCTTGGTCCGTCGGGCTGGTGGGATAGTCTGTCCTGCGCGTTCCGGAGTACTCTCGAAGTGTCGTCCAGAGGT
TTGCCGACCGCAAACAGGAT

Downstream 100 bases:

>100_bases
AGAGCCAGGATCATCATGTCTCAAATCGCAGACAAGGACGTTGCCGAGAAACCGGATGCCGATGACTCGCACAAGAACAA
GGGGCTTTATGCTGCCATCC

Product: magnesium/cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLSSIAADACDVERRNGLIKAYRANCEAISLSTDDGSGPIPDDIVWIDLVNPDRAEEQRVEKLLGVELPTREDLKDIEPS
SRLYMEDGNVFMTASLVWKADSDDPRLTDIAFILIGKRLVTIRYAEPKSFHLFIAAITRAPHEMRSGTALLLKLLETIVD
RTAEILENSVTGIDNLAADILGSQARSKRKAPRYLEDRLTNIAAYHRLISKLRVSLASLARLQTFLSTSDQAREDKGAKE
QGKSVGRDIQSLNEHASFVSGNLTFLLDASLGIINIEQNGIIKIFSIASVVFLPPTLVASVYGMNFQLMPELNWTFGYPL
ALVVMLMSAIIPFLFFRWKGWL

Sequences:

>Translated_342_residues
MLSSIAADACDVERRNGLIKAYRANCEAISLSTDDGSGPIPDDIVWIDLVNPDRAEEQRVEKLLGVELPTREDLKDIEPS
SRLYMEDGNVFMTASLVWKADSDDPRLTDIAFILIGKRLVTIRYAEPKSFHLFIAAITRAPHEMRSGTALLLKLLETIVD
RTAEILENSVTGIDNLAADILGSQARSKRKAPRYLEDRLTNIAAYHRLISKLRVSLASLARLQTFLSTSDQAREDKGAKE
QGKSVGRDIQSLNEHASFVSGNLTFLLDASLGIINIEQNGIIKIFSIASVVFLPPTLVASVYGMNFQLMPELNWTFGYPL
ALVVMLMSAIIPFLFFRWKGWL
>Mature_342_residues
MLSSIAADACDVERRNGLIKAYRANCEAISLSTDDGSGPIPDDIVWIDLVNPDRAEEQRVEKLLGVELPTREDLKDIEPS
SRLYMEDGNVFMTASLVWKADSDDPRLTDIAFILIGKRLVTIRYAEPKSFHLFIAAITRAPHEMRSGTALLLKLLETIVD
RTAEILENSVTGIDNLAADILGSQARSKRKAPRYLEDRLTNIAAYHRLISKLRVSLASLARLQTFLSTSDQAREDKGAKE
QGKSVGRDIQSLNEHASFVSGNLTFLLDASLGIINIEQNGIIKIFSIASVVFLPPTLVASVYGMNFQLMPELNWTFGYPL
ALVVMLMSAIIPFLFFRWKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=301, Percent_Identity=39.5348837209302, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 38070; Mature: 38070

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSIAADACDVERRNGLIKAYRANCEAISLSTDDGSGPIPDDIVWIDLVNPDRAEEQRV
CCCCHHHHHHHHHHHCCHHEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHH
EKLLGVELPTREDLKDIEPSSRLYMEDGNVFMTASLVWKADSDDPRLTDIAFILIGKRLV
HHHHCCCCCCHHHHHHCCCCCEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHCCEEE
TIRYAEPKSFHLFIAAITRAPHEMRSGTALLLKLLETIVDRTAEILENSVTGIDNLAADI
EEEECCCCCEEEEEEEHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGSQARSKRKAPRYLEDRLTNIAAYHRLISKLRVSLASLARLQTFLSTSDQAREDKGAKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
QGKSVGRDIQSLNEHASFVSGNLTFLLDASLGIINIEQNGIIKIFSIASVVFLPPTLVAS
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEHHHHHHHHHCCHHHHHH
VYGMNFQLMPELNWTFGYPLALVVMLMSAIIPFLFFRWKGWL
HHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLSSIAADACDVERRNGLIKAYRANCEAISLSTDDGSGPIPDDIVWIDLVNPDRAEEQRV
CCCCHHHHHHHHHHHCCHHEEECCCCCEEEEECCCCCCCCCCCEEEEEECCCCCHHHHHH
EKLLGVELPTREDLKDIEPSSRLYMEDGNVFMTASLVWKADSDDPRLTDIAFILIGKRLV
HHHHCCCCCCHHHHHHCCCCCEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHCCEEE
TIRYAEPKSFHLFIAAITRAPHEMRSGTALLLKLLETIVDRTAEILENSVTGIDNLAADI
EEEECCCCCEEEEEEEHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LGSQARSKRKAPRYLEDRLTNIAAYHRLISKLRVSLASLARLQTFLSTSDQAREDKGAKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHH
QGKSVGRDIQSLNEHASFVSGNLTFLLDASLGIINIEQNGIIKIFSIASVVFLPPTLVAS
HHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCEEHHHHHHHHHCCHHHHHH
VYGMNFQLMPELNWTFGYPLALVVMLMSAIIPFLFFRWKGWL
HHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]