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The map label for this gene is glnA [H]

Identifier: 15887947

GI number: 15887947

Start: 588760

End: 590199

Strand: Reverse

Name: glnA [H]

Synonym: Atu0602

Alternate gene names: 15887947

Gene position: 590199-588760 (Counterclockwise)

Preceding gene: 159184385

Following gene: 15887946

Centisome position: 20.77

GC content: 60.14

Gene sequence:

>1440_bases
ATGCCCGCCAAAAAAACCATGCTCCGCCCGAAGAAACAGGCAACCATGGCAAAGAAGTCTCCTCCCCTCGATCTCTCCTC
CACCCGTGGCGTTTCCTCCTGGCGCGAAGCCGCGCAATGGCTGCGCGTGCGCGGGATCGAAGACATAGAATGCATCACGC
CCGACCTTGCCGGGGTTGCGCGCGGAAAGATGATGCCGACGGCGAAATTCACGGGCGATACCTCGCTCGCGCTGCCGTCC
GCGCTCTACCGCCACACGATATCAGGCGAATATCCTGATGAGACGGCGAACTTCCGTTACGAGCCGCGCGACAGCGACCT
GAAACTAGTGCCGGATCTTTCGACGCTGTCCGTCGTGCCGTGGGAGAGCGACCCAACCGCGCAGGTGATCTGCGACGTTG
TGGATGCCGAGGGTAATTTCGTTCCCTACACGCCGCGCAACGTGCTGAAGAACGTGCTTTCGCTCTATACCGAAAAGGGC
TGGAAGCCGGTCGTAGCACCCGAAATCGAATTTTATCTCGTCGCCATGAATGACGATCCGGATTATCCGCTGCATCCGCC
GAAGGGCCGCTCCGGCCGCTCCATCGTTGGCGGTCAGAGCTATTCCATCGCCGGCATCAACGAATTCGACGAGCTGATCG
ACGACATCTACCATTTCTCGGAAAAACAGGGTCTCGAGATCGATACGCTGATCCACGAGGAAGGCCCGGCGCAGCTGGAA
ATCAACCTGCGCCACGGCGACCCGATCGAACTTGCCGACCAGGTGTTTCTTTTCAAGCGCACCATTCGCGAGGCCGCGCT
GAAACACGGCATCTACGCCACCTTCATGGCAAAGCCGATGCAGGGCCAGCCAGGTTCGGCCATGCATATCCATCAGTCGG
TGGTGGAAATCGATGGCGGACGCAATATCTTCTCCAATGCCGATGGCAGTCCTTCGAAGGTATTCTTCTCCTTCGTCGGC
GGCATGCAGCGTTATGTTCCAAACGCACTCGTCATGCTGGCGCCCTATGTGAATTCCTATCGCCGCCTGACGCCCGACAT
GGCCTGCCCGGTCAACAATGCCTGGGGTTACGACAACCGCACCACGGCTTTCCGGGTGCCGATTTCCAGCCCGCAGGCGC
GTCGCGTCGAAAACCGCCTGCCGAGTTCGGACGCCAATCCGTACCTGGCGCTTGCCGCTTCGCTCGGCTGCGGCTGGCTT
GGCATCGTCAACAATATCGAGCCGACCGAACCCACCGCCGATACGGCCAATGAAGGCTCCATCGAACTGCCGCGTGGTCT
CCTTGAGGCCGTGGCGCTGCTGGAAGGCGAGGAACAGTTCGACCGGGTGTTCGGCCATGAATTCGTGGGCCTTTATGCCG
GCCTGAAACGCGGGGAATTCGAGACCTTCATGCAGGTCATCAGCCCCTGGGAGCGCGAGTTCCTGCTTCTCAACGTGTGA

Upstream 100 bases:

>100_bases
TCTTTTCCAAGTGCCGCCGCTTGTCAATGGCGCTTTCCCCCTCGCCAATTGTCAAACTACGGTTATGATGGCTCCACCAG
AAACACAGACCCGGTGATAC

Downstream 100 bases:

>100_bases
GGAACCACGAGCATGACATGGCAAAGCCCGATTGCGCCGGGACTATCCTGGTATCAGGCAACCGTCGGCGAGCGGCCGGA
CTATCCCGCTCTCGACGGGT

Product: glutamine synthetase

Products: NA

Alternate protein names: Gamma-Glu-Put synthetase; Glutamate--putrescine ligase [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MPAKKTMLRPKKQATMAKKSPPLDLSSTRGVSSWREAAQWLRVRGIEDIECITPDLAGVARGKMMPTAKFTGDTSLALPS
ALYRHTISGEYPDETANFRYEPRDSDLKLVPDLSTLSVVPWESDPTAQVICDVVDAEGNFVPYTPRNVLKNVLSLYTEKG
WKPVVAPEIEFYLVAMNDDPDYPLHPPKGRSGRSIVGGQSYSIAGINEFDELIDDIYHFSEKQGLEIDTLIHEEGPAQLE
INLRHGDPIELADQVFLFKRTIREAALKHGIYATFMAKPMQGQPGSAMHIHQSVVEIDGGRNIFSNADGSPSKVFFSFVG
GMQRYVPNALVMLAPYVNSYRRLTPDMACPVNNAWGYDNRTTAFRVPISSPQARRVENRLPSSDANPYLALAASLGCGWL
GIVNNIEPTEPTADTANEGSIELPRGLLEAVALLEGEEQFDRVFGHEFVGLYAGLKRGEFETFMQVISPWEREFLLLNV

Sequences:

>Translated_479_residues
MPAKKTMLRPKKQATMAKKSPPLDLSSTRGVSSWREAAQWLRVRGIEDIECITPDLAGVARGKMMPTAKFTGDTSLALPS
ALYRHTISGEYPDETANFRYEPRDSDLKLVPDLSTLSVVPWESDPTAQVICDVVDAEGNFVPYTPRNVLKNVLSLYTEKG
WKPVVAPEIEFYLVAMNDDPDYPLHPPKGRSGRSIVGGQSYSIAGINEFDELIDDIYHFSEKQGLEIDTLIHEEGPAQLE
INLRHGDPIELADQVFLFKRTIREAALKHGIYATFMAKPMQGQPGSAMHIHQSVVEIDGGRNIFSNADGSPSKVFFSFVG
GMQRYVPNALVMLAPYVNSYRRLTPDMACPVNNAWGYDNRTTAFRVPISSPQARRVENRLPSSDANPYLALAASLGCGWL
GIVNNIEPTEPTADTANEGSIELPRGLLEAVALLEGEEQFDRVFGHEFVGLYAGLKRGEFETFMQVISPWEREFLLLNV
>Mature_478_residues
PAKKTMLRPKKQATMAKKSPPLDLSSTRGVSSWREAAQWLRVRGIEDIECITPDLAGVARGKMMPTAKFTGDTSLALPSA
LYRHTISGEYPDETANFRYEPRDSDLKLVPDLSTLSVVPWESDPTAQVICDVVDAEGNFVPYTPRNVLKNVLSLYTEKGW
KPVVAPEIEFYLVAMNDDPDYPLHPPKGRSGRSIVGGQSYSIAGINEFDELIDDIYHFSEKQGLEIDTLIHEEGPAQLEI
NLRHGDPIELADQVFLFKRTIREAALKHGIYATFMAKPMQGQPGSAMHIHQSVVEIDGGRNIFSNADGSPSKVFFSFVGG
MQRYVPNALVMLAPYVNSYRRLTPDMACPVNNAWGYDNRTTAFRVPISSPQARRVENRLPSSDANPYLALAASLGCGWLG
IVNNIEPTEPTADTANEGSIELPRGLLEAVALLEGEEQFDRVFGHEFVGLYAGLKRGEFETFMQVISPWEREFLLLNV

Specific function: Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine [H]

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=424, Percent_Identity=27.122641509434, Blast_Score=142, Evalue=5e-34,
Organism=Escherichia coli, GI87081870, Length=462, Percent_Identity=33.1168831168831, Blast_Score=231, Evalue=8e-62,
Organism=Escherichia coli, GI1790301, Length=406, Percent_Identity=30.2955665024631, Blast_Score=145, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.11 [H]

Molecular weight: Translated: 53180; Mature: 53049

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAKKTMLRPKKQATMAKKSPPLDLSSTRGVSSWREAAQWLRVRGIEDIECITPDLAGVA
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
RGKMMPTAKFTGDTSLALPSALYRHTISGEYPDETANFRYEPRDSDLKLVPDLSTLSVVP
CCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCEEECCCCCEEEEC
WESDPTAQVICDVVDAEGNFVPYTPRNVLKNVLSLYTEKGWKPVVAPEIEFYLVAMNDDP
CCCCCHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCC
DYPLHPPKGRSGRSIVGGQSYSIAGINEFDELIDDIYHFSEKQGLEIDTLIHEEGPAQLE
CCCCCCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEE
INLRHGDPIELADQVFLFKRTIREAALKHGIYATFMAKPMQGQPGSAMHIHQSVVEIDGG
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHEEECCC
RNIFSNADGSPSKVFFSFVGGMQRYVPNALVMLAPYVNSYRRLTPDMACPVNNAWGYDNR
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TTAFRVPISSPQARRVENRLPSSDANPYLALAASLGCGWLGIVNNIEPTEPTADTANEGS
CEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEHHCCCCHHHHCCCCCCCCCCCCCCCCCC
IELPRGLLEAVALLEGEEQFDRVFGHEFVGLYAGLKRGEFETFMQVISPWEREFLLLNV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
PAKKTMLRPKKQATMAKKSPPLDLSSTRGVSSWREAAQWLRVRGIEDIECITPDLAGVA
CCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
RGKMMPTAKFTGDTSLALPSALYRHTISGEYPDETANFRYEPRDSDLKLVPDLSTLSVVP
CCCCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCEEECCCCCEEEEC
WESDPTAQVICDVVDAEGNFVPYTPRNVLKNVLSLYTEKGWKPVVAPEIEFYLVAMNDDP
CCCCCHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEECCCEEEEEEEECCCC
DYPLHPPKGRSGRSIVGGQSYSIAGINEFDELIDDIYHFSEKQGLEIDTLIHEEGPAQLE
CCCCCCCCCCCCCEEECCCCEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEE
INLRHGDPIELADQVFLFKRTIREAALKHGIYATFMAKPMQGQPGSAMHIHQSVVEIDGG
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHEEECCC
RNIFSNADGSPSKVFFSFVGGMQRYVPNALVMLAPYVNSYRRLTPDMACPVNNAWGYDNR
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TTAFRVPISSPQARRVENRLPSSDANPYLALAASLGCGWLGIVNNIEPTEPTADTANEGS
CEEEEECCCCCHHHHHHHCCCCCCCCCCEEEEHHCCCCHHHHCCCCCCCCCCCCCCCCCC
IELPRGLLEAVALLEGEEQFDRVFGHEFVGLYAGLKRGEFETFMQVISPWEREFLLLNV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]