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The map label for this gene is pfs [H]

Identifier: 15887631

GI number: 15887631

Start: 276734

End: 277372

Strand: Reverse

Name: pfs [H]

Synonym: Atu0282

Alternate gene names: 15887631

Gene position: 277372-276734 (Counterclockwise)

Preceding gene: 15887632

Following gene: 15887630

Centisome position: 9.76

GC content: 59.31

Gene sequence:

>639_bases
ATGAGCTACCGGCTTTCGCATGTTGCGGATAAATCCGTTCTTTTCGTTATGGCGGCCTCCGCTGAATACGGCCCCCATCT
GCAGGCGCGCATCGCGCCACTCATGACCGGCGTCGGCCCAGTCGAGGCGGCCATTTCGGTGACCGCCATTCTTGCCGGTC
TCGATGCCGCCGACAATTTGCCCGACCTCGTCGTTTCGCTTGGCTCCGCGGGTTCGCGGACATTGCAACAGACGGGCATC
TATCAGGCGGTTTCGGTTTCCTATCGCGATATGGATGCATCCGCCTTCGGTTTCGAAAAGGGGCGAACGCCGTTTCTCGA
TCTGCCCGCCGAAGTTGCCCTGCCTTTGCGGATACCCGATATTGCCGAGGCTAGGCTTTCCACCGGCGGCAACGTCGTTT
CCGGAGAGGCCTATGGGTTGATCGATGCCGATATGGTGGAAATGGAGACCTTTGCGGTCCTGCGAGCATGTCAGCGCTTC
GGTGTGCCGCTCATCAGCCTGCGCGGTATTTCCGACGGCAAGGCCGATGTGAACCATGTGGATGACTGGACGGCGTATCT
TGATATCATCGATGAAAAGCTCGCCAATGCCGTCGATCGGCTCTGCCGCGCCATCGAGGATGGGGTGATTGCCCTTTGA

Upstream 100 bases:

>100_bases
CGGATGGTCGTGCCTATGCCCTGTCCGATGGACCGGCGAAGCTGATCGCCTCGATGACGGGCACGATGATGGTGGTGAAG
GGGCGCGAGGATATTACCGG

Downstream 100 bases:

>100_bases
AACCTTGCGATTTTCGCAAATTTCCGCCCTTTGACGCCCGCTTCCGGGTTGCCTAAAGCCCCGCTTTTCTTTAAAGGCTC
GCCATGACCCAGATAGCCCA

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSYRLSHVADKSVLFVMAASAEYGPHLQARIAPLMTGVGPVEAAISVTAILAGLDAADNLPDLVVSLGSAGSRTLQQTGI
YQAVSVSYRDMDASAFGFEKGRTPFLDLPAEVALPLRIPDIAEARLSTGGNVVSGEAYGLIDADMVEMETFAVLRACQRF
GVPLISLRGISDGKADVNHVDDWTAYLDIIDEKLANAVDRLCRAIEDGVIAL

Sequences:

>Translated_212_residues
MSYRLSHVADKSVLFVMAASAEYGPHLQARIAPLMTGVGPVEAAISVTAILAGLDAADNLPDLVVSLGSAGSRTLQQTGI
YQAVSVSYRDMDASAFGFEKGRTPFLDLPAEVALPLRIPDIAEARLSTGGNVVSGEAYGLIDADMVEMETFAVLRACQRF
GVPLISLRGISDGKADVNHVDDWTAYLDIIDEKLANAVDRLCRAIEDGVIAL
>Mature_211_residues
SYRLSHVADKSVLFVMAASAEYGPHLQARIAPLMTGVGPVEAAISVTAILAGLDAADNLPDLVVSLGSAGSRTLQQTGIY
QAVSVSYRDMDASAFGFEKGRTPFLDLPAEVALPLRIPDIAEARLSTGGNVVSGEAYGLIDADMVEMETFAVLRACQRFG
VPLISLRGISDGKADVNHVDDWTAYLDIIDEKLANAVDRLCRAIEDGVIAL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 22466; Mature: 22335

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRLSHVADKSVLFVMAASAEYGPHLQARIAPLMTGVGPVEAAISVTAILAGLDAADNL
CCCCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
PDLVVSLGSAGSRTLQQTGIYQAVSVSYRDMDASAFGFEKGRTPFLDLPAEVALPLRIPD
HHHHHHHCCCCCHHHHHHCCHHHEEEHHCCCCCHHCCCCCCCCCCEECCHHHEEEECCCC
IAEARLSTGGNVVSGEAYGLIDADMVEMETFAVLRACQRFGVPLISLRGISDGKADVNHV
HHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
DDWTAYLDIIDEKLANAVDRLCRAIEDGVIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SYRLSHVADKSVLFVMAASAEYGPHLQARIAPLMTGVGPVEAAISVTAILAGLDAADNL
CCCCCHHCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
PDLVVSLGSAGSRTLQQTGIYQAVSVSYRDMDASAFGFEKGRTPFLDLPAEVALPLRIPD
HHHHHHHCCCCCHHHHHHCCHHHEEEHHCCCCCHHCCCCCCCCCCEECCHHHEEEECCCC
IAEARLSTGGNVVSGEAYGLIDADMVEMETFAVLRACQRFGVPLISLRGISDGKADVNHV
HHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
DDWTAYLDIIDEKLANAVDRLCRAIEDGVIAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA