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The map label for this gene is glnA [H]

Identifier: 15887546

GI number: 15887546

Start: 196923

End: 198281

Strand: Direct

Name: glnA [H]

Synonym: Atu0193

Alternate gene names: 15887546

Gene position: 196923-198281 (Clockwise)

Preceding gene: 159184203

Following gene: 15887547

Centisome position: 6.93

GC content: 59.68

Gene sequence:

>1359_bases
ATGTATGATATTGAAAACGCAAAGAAATTTTTCGCTGATAATCCCGATATCGAAATTCTCGAAGCTTTCGTCATAGATGC
GAACGGCGTTCCGCGCGGTAAATGGATTCCGCGTGAGAGAGCAATTGACGTGCTTGAAAAGGGAATGGCGATCCCGCGAT
CCGTTTATGCGCTGGATATCTGGGGCCGGGATGTGCACGCCGCAGGTCTCGCCGAAGGCACGGGTGATCCTGATGGTTTT
TGTTTCCCCGTTCCCGGTACGCTGTCACGGGTAACATGGCTTGGCCGGCCGACGGCGCAGGTTCTGCTGGCGATGAAAAA
CGCGGATGGGACCGGATTTTATGGTGATCCGCGCCATGTTCTGTCGCAGGTTCTGAACGCCTATAAAAAGGCTGGCCTCA
CGCCGGTCGTGGCGACCGAACTGGAATTCTACCTCATCGATCCCGTCCGCTCGGCGCTTGACCCGGTGCGCCCGCCGCAC
AGCCGCGAAGGTCGCTGGCACACCGGCCAGACGCAGGTTCTATCGATTTCCGAATTGCAGGATTTCGAGGATGTCTTCCA
TGATATCGCGACAGCCTGCCGCGCCCAGGGTGTGCTTGCAGATACGACGCTGCGGGAAAATGGCCCCGGGCAATATGAGA
TCAACCTCAACCACGTGCCGGATGCCCTGCAGGCCGCCGATTTTGCCGTCTTCCTGAAACGCATCGTCAAAGGTGTGGCG
CGACGGCACGAACTCGACGCCACCTTCATGGCCAAGCCCTATGGGCTGCAGGCCGGCAACGGCATGCATGTGCATTTTTC
CGTTCTCGACAGGGACGGCAGGAATATCTACGCCGGGGAAAACGGTCCGTCGGATGCGCTGATGCACTCGGTCGGCGGCC
TGTTGGAAAACATGGGGGAGAGCATGGCGATCTTCGCTCCCCATGCCAATTCCTATCGCCGCCTCACCCCAAGCGAACAC
GCGCCGACCTACGCTTCGTGGGGTATCGACAACCGCTCGGCGGCGGTCCGCGTCATCGTGGCCAGCAAGGCGGCAACCCG
CATCGAACACCGCGTCGCCGGCGCCGACACCAATCCCTACCTGGTCCTCGCGATGATCCTCAGCGCCGCTATCGCCGGCA
TGAAGGAGAAGCGCCAGCCCGGCGGCGCGATTGCCGGTGACAGCCACGCGATCAATCACGAACCGCTTCCCACCAACTGG
GACTATGCATTGCAGCGCTTCACGCGTTCGAGCTTTGCCTATGCGACGCTCGGCCAGAAGTACCGCACGCTGTTTTCCGC
CTGCAAGCAGCAGGAGCTTTCCGAATTTTCCCTGCGTGTAACCGACGTCGAATATGACGCCTATATCAGGACGGTGTGA

Upstream 100 bases:

>100_bases
ATCATGGTGGCGAGGTTTCTCATCTATCAGCAGCAGGACGACTTTCGTTAGCGAAACTCGCTGCGCATGAAACGAGATGG
AAACGGCTTGCTGGTGCATA

Downstream 100 bases:

>100_bases
GATGGCTGAGGTAACGAACATTCCCAATCCCGGCCACACATCGTCGTGGTATGCGGCCTCCGCCAATGTCAAATCCGTGC
GACCGACGCTTGAGGGCGCG

Product: glutamine synthetase

Products: NA

Alternate protein names: Gamma-Glu-Put synthetase; Glutamate--putrescine ligase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MYDIENAKKFFADNPDIEILEAFVIDANGVPRGKWIPRERAIDVLEKGMAIPRSVYALDIWGRDVHAAGLAEGTGDPDGF
CFPVPGTLSRVTWLGRPTAQVLLAMKNADGTGFYGDPRHVLSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDPVRPPH
SREGRWHTGQTQVLSISELQDFEDVFHDIATACRAQGVLADTTLRENGPGQYEINLNHVPDALQAADFAVFLKRIVKGVA
RRHELDATFMAKPYGLQAGNGMHVHFSVLDRDGRNIYAGENGPSDALMHSVGGLLENMGESMAIFAPHANSYRRLTPSEH
APTYASWGIDNRSAAVRVIVASKAATRIEHRVAGADTNPYLVLAMILSAAIAGMKEKRQPGGAIAGDSHAINHEPLPTNW
DYALQRFTRSSFAYATLGQKYRTLFSACKQQELSEFSLRVTDVEYDAYIRTV

Sequences:

>Translated_452_residues
MYDIENAKKFFADNPDIEILEAFVIDANGVPRGKWIPRERAIDVLEKGMAIPRSVYALDIWGRDVHAAGLAEGTGDPDGF
CFPVPGTLSRVTWLGRPTAQVLLAMKNADGTGFYGDPRHVLSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDPVRPPH
SREGRWHTGQTQVLSISELQDFEDVFHDIATACRAQGVLADTTLRENGPGQYEINLNHVPDALQAADFAVFLKRIVKGVA
RRHELDATFMAKPYGLQAGNGMHVHFSVLDRDGRNIYAGENGPSDALMHSVGGLLENMGESMAIFAPHANSYRRLTPSEH
APTYASWGIDNRSAAVRVIVASKAATRIEHRVAGADTNPYLVLAMILSAAIAGMKEKRQPGGAIAGDSHAINHEPLPTNW
DYALQRFTRSSFAYATLGQKYRTLFSACKQQELSEFSLRVTDVEYDAYIRTV
>Mature_452_residues
MYDIENAKKFFADNPDIEILEAFVIDANGVPRGKWIPRERAIDVLEKGMAIPRSVYALDIWGRDVHAAGLAEGTGDPDGF
CFPVPGTLSRVTWLGRPTAQVLLAMKNADGTGFYGDPRHVLSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDPVRPPH
SREGRWHTGQTQVLSISELQDFEDVFHDIATACRAQGVLADTTLRENGPGQYEINLNHVPDALQAADFAVFLKRIVKGVA
RRHELDATFMAKPYGLQAGNGMHVHFSVLDRDGRNIYAGENGPSDALMHSVGGLLENMGESMAIFAPHANSYRRLTPSEH
APTYASWGIDNRSAAVRVIVASKAATRIEHRVAGADTNPYLVLAMILSAAIAGMKEKRQPGGAIAGDSHAINHEPLPTNW
DYALQRFTRSSFAYATLGQKYRTLFSACKQQELSEFSLRVTDVEYDAYIRTV

Specific function: Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine [H]

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=434, Percent_Identity=22.3502304147465, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081870, Length=448, Percent_Identity=37.2767857142857, Blast_Score=310, Evalue=9e-86,
Organism=Escherichia coli, GI1790301, Length=302, Percent_Identity=28.1456953642384, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.11 [H]

Molecular weight: Translated: 49690; Mature: 49690

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDIENAKKFFADNPDIEILEAFVIDANGVPRGKWIPRERAIDVLEKGMAIPRSVYALDI
CCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
WGRDVHAAGLAEGTGDPDGFCFPVPGTLSRVTWLGRPTAQVLLAMKNADGTGFYGDPRHV
CCCCCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCHHHEEEEEECCCCCCCCCCHHHH
LSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDPVRPPHSREGRWHTGQTQVLSISELQ
HHHHHHHHHHCCCCEEEECCEEEEEECHHHHHHCCCCCCCCCCCCEECCCEEEEEHHHHH
DFEDVFHDIATACRAQGVLADTTLRENGPGQYEINLNHVPDALQAADFAVFLKRIVKGVA
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RRHELDATFMAKPYGLQAGNGMHVHFSVLDRDGRNIYAGENGPSDALMHSVGGLLENMGE
HHHCCCHHEEECCCCCCCCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCC
SMAIFAPHANSYRRLTPSEHAPTYASWGIDNRSAAVRVIVASKAATRIEHRVAGADTNPY
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHCCCCCCHH
LVLAMILSAAIAGMKEKRQPGGAIAGDSHAINHEPLPTNWDYALQRFTRSSFAYATLGQK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YRTLFSACKQQELSEFSLRVTDVEYDAYIRTV
HHHHHHHHHHHHHHHHEEEEEEEEECEEEECC
>Mature Secondary Structure
MYDIENAKKFFADNPDIEILEAFVIDANGVPRGKWIPRERAIDVLEKGMAIPRSVYALDI
CCCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEE
WGRDVHAAGLAEGTGDPDGFCFPVPGTLSRVTWLGRPTAQVLLAMKNADGTGFYGDPRHV
CCCCCCCCCCCCCCCCCCCEEECCCCHHHHHEECCCCHHHEEEEEECCCCCCCCCCHHHH
LSQVLNAYKKAGLTPVVATELEFYLIDPVRSALDPVRPPHSREGRWHTGQTQVLSISELQ
HHHHHHHHHHCCCCEEEECCEEEEEECHHHHHHCCCCCCCCCCCCEECCCEEEEEHHHHH
DFEDVFHDIATACRAQGVLADTTLRENGPGQYEINLNHVPDALQAADFAVFLKRIVKGVA
HHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RRHELDATFMAKPYGLQAGNGMHVHFSVLDRDGRNIYAGENGPSDALMHSVGGLLENMGE
HHHCCCHHEEECCCCCCCCCCCEEEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHCCC
SMAIFAPHANSYRRLTPSEHAPTYASWGIDNRSAAVRVIVASKAATRIEHRVAGADTNPY
CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHCCCCCCHH
LVLAMILSAAIAGMKEKRQPGGAIAGDSHAINHEPLPTNWDYALQRFTRSSFAYATLGQK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
YRTLFSACKQQELSEFSLRVTDVEYDAYIRTV
HHHHHHHHHHHHHHHHEEEEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]