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The map label for this gene is pbpC [H]

Identifier: 15887457

GI number: 15887457

Start: 106484

End: 108778

Strand: Reverse

Name: pbpC [H]

Synonym: Atu0103

Alternate gene names: 15887457

Gene position: 108778-106484 (Counterclockwise)

Preceding gene: 15887458

Following gene: 159184156

Centisome position: 3.83

GC content: 62.22

Gene sequence:

>2295_bases
ATGGCAGGCAAGGGTAAATCACGCGAACGGGTAGAACCTTCTTTCGGGGATTTTCACGAGTCCGGTGATGACCTGCGTCT
TGACGCCAGCGAACGCATCAGCGGAGCCTCAAAACAGCAAGCCAAGAAACCGAGACCGGCATCCGGCCGTACCAAATCCC
GGAAGAAAGAAAAGCGTAGCCGCAATTCGGGCCGGGGCGTGACGGGCTTCATCCGCTCCCTCTTCTACTGGTGCATCGTG
CTCGGCATCTGGGGCGGTATCGGCGTTGCCGGGCTTGTCCTTTATTATGGTGCGCGCATGCCGAGCGCCAGCAGCTGGTC
CATTCCCGAACGGCCGCCGAATGTGAAGATCGTTTCGGTCAATGGCAGCGTGCTTGCCAATCGCGGCACCACCGGCGGCG
AGGCGCTCGCGCTGGAAGACATGTCGCCCTATATTCCGCAGGCGGTCATGGCGATCGAAGATCGCCGGTTTTATTCGCAT
TTCGGGGTCGATCCGCTGGGTCTCGGACGCGCCATCGTGACGAATGTGCTGACGGGACGAGCTGTCCAGGGCGGATCGAC
GCTGACGCAGCAACTGGCGAAAAACCTGTTTCTCTCGCCCGACCGGACGCTGGAACGCAAGGTGCAGGAAGTGCTTCTGT
CCTTCTGGCTGGAGCACGAATTCACCAAGGACCAGATCCTCGCGATGTATCTCAATCGCGTCTATTTCGGCTCCAATGCC
TATGGCGTCGAAGCGGCTTCCCGGCGCTACTTCAACAAATCCGCGCGCGACGTCAATCTGGGCGAAGCGGCAATGCTGGC
CGGGCTTCTCAAAGCGCCCTCACGCCTTTCGCCGGCGCGCGATCCGCAGGCGGCGGAAGAGCGGGCGCAGGTGGTGCTGC
AATCCATGCGCGATGTCGGCTTCATCACCGATGACGAAATCAAGACCGCGATGTCGCAGCCGCCGACAAAGGCGAAGCGG
TTCTGGTCGGGTGCCGAACATTACGCCGCCGATATGGTGCTGGAGGAAGTCCGCGGCCTGGTGGGCGAGGTCAAGCAGGA
CATCGTTGTCGATACAACCATCGACCCCAATCTCGAGCGCGACGCCGAAAAGGCGCTGACCCATGTGCTGCAGGGTGACG
GCAAAAAACAGGGTGCCTCGCAGGCGGCGCTGGTTTCGATAGACGGTACGGGCGCGATCCGGGCCGTCGTCGGCGGGGCA
GATTATGCGCAAAGCCAGTTCAACCGCGCCGTAAAGGCAAAACGGCAACCGGGTTCCGCCTTCAAGCCCTTCGTTTACGT
CGCCGCACTCGAATCGGGGCTTACCCCCTACACGATCCGCAATGACGGGCCGGTGCGCATCGGAAACTGGACACCGGAAA
ACTACGAAAAGAAGTATCGCGGCGAAGTCACGCTCGCCACCGCGCTTGCCAATTCACTGAACACGATCGCCGCACAACTG
GTGATGGAGGTCGGCCCGGAACGGGTGACGCAGGTGGCGCATCGCATGGGCATCGAATCGGAGCTGCAGAACAATGCCTC
CATCGCCCTCGGCACCTCTGAGGTGTCGCTGATGGAGCTGACCGCCTCCTATGCTCCCTTCATGAATGGCGGCTACAAGG
CGACGCCGCACATCGTCAAGCGTATCACCGATGCCGACGGCAAGGTTCTTTACGAAAACAAATACGATAATCCACCGCGC
GTGCTGAGCGAAGAGATTGCCGCGACCATGAACGGCATGTTGTCCCGCGTCATCACCGAAGGCACCGGCAAGGCCGCGCG
CCTGCAAGGCTGGCAGGCGGCAGGAAAATCCGGCACGACCCAGTCCTTCCGCGATGCACTTTTTGTCGGCTACACAAGCA
ACCTCACCACCGGCGTCTGGTTCGGCAATGACGACGGCACCTCCATGAAGAAGGTCACCGGCGGCGGACTGCCGGCACGG
GCATGGAAGGATTTCATGACCGCTGCCCATTCCGGGCTCTCGCCTTCGCCGCTTTTCGGCCTCGGCGCAGGTGGCGTACC
GCCGCTCGGGGACATGCAGCAGCCGGCACCGGAAGCCGCCCCCTCATCCATCGGCGAGATCATTTCCAATGCGCTGGGTG
GCGGAACGACGGACACCCGCGCCTATCCCGATGCGCCGGTTTCACCCAACCAGCCGGGCATGGCCATGCCGCCGGCGAAC
ATACCCTCCCGCGATATCGAACCAGGCTACCAGGCCGGCAACGGGCCCGTGCCACCCGCCGACATAGGCGGCCAGGCCCC
CGCACAATCGGGGCCGAAGCAGACGACGCTGCTTGACATTCTGATGGGAAATTGA

Upstream 100 bases:

>100_bases
CCAGGACTTAACCCCGCCTTAAATCGCCGCATTTACACTCTTCATCCTGGATTAAGGATCGCGCAGGCATAGAGACGCGA
ATAGGAGCGACTTAGGCTGG

Downstream 100 bases:

>100_bases
CCCGCGTCTGGTAATGGGCCAGCGGAGATCATCACGAATGGCGAGATGGTAGCAACACACTCGCCCTCCCGAAAAACCCC
GCTTTTCCGGAGACTTTGCC

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-1F; Penicillin-binding protein F [H]

Number of amino acids: Translated: 764; Mature: 763

Protein sequence:

>764_residues
MAGKGKSRERVEPSFGDFHESGDDLRLDASERISGASKQQAKKPRPASGRTKSRKKEKRSRNSGRGVTGFIRSLFYWCIV
LGIWGGIGVAGLVLYYGARMPSASSWSIPERPPNVKIVSVNGSVLANRGTTGGEALALEDMSPYIPQAVMAIEDRRFYSH
FGVDPLGLGRAIVTNVLTGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVLLSFWLEHEFTKDQILAMYLNRVYFGSNA
YGVEAASRRYFNKSARDVNLGEAAMLAGLLKAPSRLSPARDPQAAEERAQVVLQSMRDVGFITDDEIKTAMSQPPTKAKR
FWSGAEHYAADMVLEEVRGLVGEVKQDIVVDTTIDPNLERDAEKALTHVLQGDGKKQGASQAALVSIDGTGAIRAVVGGA
DYAQSQFNRAVKAKRQPGSAFKPFVYVAALESGLTPYTIRNDGPVRIGNWTPENYEKKYRGEVTLATALANSLNTIAAQL
VMEVGPERVTQVAHRMGIESELQNNASIALGTSEVSLMELTASYAPFMNGGYKATPHIVKRITDADGKVLYENKYDNPPR
VLSEEIAATMNGMLSRVITEGTGKAARLQGWQAAGKSGTTQSFRDALFVGYTSNLTTGVWFGNDDGTSMKKVTGGGLPAR
AWKDFMTAAHSGLSPSPLFGLGAGGVPPLGDMQQPAPEAAPSSIGEIISNALGGGTTDTRAYPDAPVSPNQPGMAMPPAN
IPSRDIEPGYQAGNGPVPPADIGGQAPAQSGPKQTTLLDILMGN

Sequences:

>Translated_764_residues
MAGKGKSRERVEPSFGDFHESGDDLRLDASERISGASKQQAKKPRPASGRTKSRKKEKRSRNSGRGVTGFIRSLFYWCIV
LGIWGGIGVAGLVLYYGARMPSASSWSIPERPPNVKIVSVNGSVLANRGTTGGEALALEDMSPYIPQAVMAIEDRRFYSH
FGVDPLGLGRAIVTNVLTGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVLLSFWLEHEFTKDQILAMYLNRVYFGSNA
YGVEAASRRYFNKSARDVNLGEAAMLAGLLKAPSRLSPARDPQAAEERAQVVLQSMRDVGFITDDEIKTAMSQPPTKAKR
FWSGAEHYAADMVLEEVRGLVGEVKQDIVVDTTIDPNLERDAEKALTHVLQGDGKKQGASQAALVSIDGTGAIRAVVGGA
DYAQSQFNRAVKAKRQPGSAFKPFVYVAALESGLTPYTIRNDGPVRIGNWTPENYEKKYRGEVTLATALANSLNTIAAQL
VMEVGPERVTQVAHRMGIESELQNNASIALGTSEVSLMELTASYAPFMNGGYKATPHIVKRITDADGKVLYENKYDNPPR
VLSEEIAATMNGMLSRVITEGTGKAARLQGWQAAGKSGTTQSFRDALFVGYTSNLTTGVWFGNDDGTSMKKVTGGGLPAR
AWKDFMTAAHSGLSPSPLFGLGAGGVPPLGDMQQPAPEAAPSSIGEIISNALGGGTTDTRAYPDAPVSPNQPGMAMPPAN
IPSRDIEPGYQAGNGPVPPADIGGQAPAQSGPKQTTLLDILMGN
>Mature_763_residues
AGKGKSRERVEPSFGDFHESGDDLRLDASERISGASKQQAKKPRPASGRTKSRKKEKRSRNSGRGVTGFIRSLFYWCIVL
GIWGGIGVAGLVLYYGARMPSASSWSIPERPPNVKIVSVNGSVLANRGTTGGEALALEDMSPYIPQAVMAIEDRRFYSHF
GVDPLGLGRAIVTNVLTGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVLLSFWLEHEFTKDQILAMYLNRVYFGSNAY
GVEAASRRYFNKSARDVNLGEAAMLAGLLKAPSRLSPARDPQAAEERAQVVLQSMRDVGFITDDEIKTAMSQPPTKAKRF
WSGAEHYAADMVLEEVRGLVGEVKQDIVVDTTIDPNLERDAEKALTHVLQGDGKKQGASQAALVSIDGTGAIRAVVGGAD
YAQSQFNRAVKAKRQPGSAFKPFVYVAALESGLTPYTIRNDGPVRIGNWTPENYEKKYRGEVTLATALANSLNTIAAQLV
MEVGPERVTQVAHRMGIESELQNNASIALGTSEVSLMELTASYAPFMNGGYKATPHIVKRITDADGKVLYENKYDNPPRV
LSEEIAATMNGMLSRVITEGTGKAARLQGWQAAGKSGTTQSFRDALFVGYTSNLTTGVWFGNDDGTSMKKVTGGGLPARA
WKDFMTAAHSGLSPSPLFGLGAGGVPPLGDMQQPAPEAAPSSIGEIISNALGGGTTDTRAYPDAPVSPNQPGMAMPPANI
PSRDIEPGYQAGNGPVPPADIGGQAPAQSGPKQTTLLDILMGN

Specific function: Cell wall formation. May be involved in outgrowth of the germinated spore or it could function in the synthesis of the germ cell wall [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1788867, Length=566, Percent_Identity=30.3886925795053, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1786343, Length=508, Percent_Identity=30.511811023622, Blast_Score=211, Evalue=2e-55,
Organism=Escherichia coli, GI87082258, Length=310, Percent_Identity=35.8064516129032, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1789601, Length=237, Percent_Identity=32.9113924050633, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 81722; Mature: 81591

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS01159 WW_DOMAIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKGKSRERVEPSFGDFHESGDDLRLDASERISGASKQQAKKPRPASGRTKSRKKEKRS
CCCCCCCCCCCCCCCCCHHCCCCCEEECHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHH
RNSGRGVTGFIRSLFYWCIVLGIWGGIGVAGLVLYYGARMPSASSWSIPERPPNVKIVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
NGSVLANRGTTGGEALALEDMSPYIPQAVMAIEDRRFYSHFGVDPLGLGRAIVTNVLTGR
CCCEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCC
AVQGGSTLTQQLAKNLFLSPDRTLERKVQEVLLSFWLEHEFTKDQILAMYLNRVYFGSNA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
YGVEAASRRYFNKSARDVNLGEAAMLAGLLKAPSRLSPARDPQAAEERAQVVLQSMRDVG
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCC
FITDDEIKTAMSQPPTKAKRFWSGAEHYAADMVLEEVRGLVGEVKQDIVVDTTIDPNLER
CCCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHH
DAEKALTHVLQGDGKKQGASQAALVSIDGTGAIRAVVGGADYAQSQFNRAVKAKRQPGSA
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
FKPFVYVAALESGLTPYTIRNDGPVRIGNWTPENYEKKYRGEVTLATALANSLNTIAAQL
CCHHHHHHHHHCCCCCEEECCCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VMEVGPERVTQVAHRMGIESELQNNASIALGTSEVSLMELTASYAPFMNGGYKATPHIVK
HHHHCHHHHHHHHHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHCHHHCCCCCCCHHHHH
RITDADGKVLYENKYDNPPRVLSEEIAATMNGMLSRVITEGTGKAARLQGWQAAGKSGTT
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCH
QSFRDALFVGYTSNLTTGVWFGNDDGTSMKKVTGGGLPARAWKDFMTAAHSGLSPSPLFG
HHHHHHEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LGAGGVPPLGDMQQPAPEAAPSSIGEIISNALGGGTTDTRAYPDAPVSPNQPGMAMPPAN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IPSRDIEPGYQAGNGPVPPADIGGQAPAQSGPKQTTLLDILMGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECC
>Mature Secondary Structure 
AGKGKSRERVEPSFGDFHESGDDLRLDASERISGASKQQAKKPRPASGRTKSRKKEKRS
CCCCCCCCCCCCCCCCHHCCCCCEEECHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHHH
RNSGRGVTGFIRSLFYWCIVLGIWGGIGVAGLVLYYGARMPSASSWSIPERPPNVKIVSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEE
NGSVLANRGTTGGEALALEDMSPYIPQAVMAIEDRRFYSHFGVDPLGLGRAIVTNVLTGR
CCCEEECCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHCC
AVQGGSTLTQQLAKNLFLSPDRTLERKVQEVLLSFWLEHEFTKDQILAMYLNRVYFGSNA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
YGVEAASRRYFNKSARDVNLGEAAMLAGLLKAPSRLSPARDPQAAEERAQVVLQSMRDVG
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHCC
FITDDEIKTAMSQPPTKAKRFWSGAEHYAADMVLEEVRGLVGEVKQDIVVDTTIDPNLER
CCCCHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHH
DAEKALTHVLQGDGKKQGASQAALVSIDGTGAIRAVVGGADYAQSQFNRAVKAKRQPGSA
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCC
FKPFVYVAALESGLTPYTIRNDGPVRIGNWTPENYEKKYRGEVTLATALANSLNTIAAQL
CCHHHHHHHHHCCCCCEEECCCCCEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VMEVGPERVTQVAHRMGIESELQNNASIALGTSEVSLMELTASYAPFMNGGYKATPHIVK
HHHHCHHHHHHHHHHHCCHHHHCCCCEEEECCCCHHHHHHHHHHCHHHCCCCCCCHHHHH
RITDADGKVLYENKYDNPPRVLSEEIAATMNGMLSRVITEGTGKAARLQGWQAAGKSGTT
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHCCCCCCH
QSFRDALFVGYTSNLTTGVWFGNDDGTSMKKVTGGGLPARAWKDFMTAAHSGLSPSPLFG
HHHHHHEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
LGAGGVPPLGDMQQPAPEAAPSSIGEIISNALGGGTTDTRAYPDAPVSPNQPGMAMPPAN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
IPSRDIEPGYQAGNGPVPPADIGGQAPAQSGPKQTTLLDILMGN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8335642; 1459957 [H]