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The map label for this gene is dnaQ [H]

Identifier: 15887364

GI number: 15887364

Start: 3110

End: 3808

Strand: Direct

Name: dnaQ [H]

Synonym: Atu0005

Alternate gene names: 15887364

Gene position: 3110-3808 (Clockwise)

Preceding gene: 159184121

Following gene: 159184122

Centisome position: 0.11

GC content: 57.65

Gene sequence:

>699_bases
ATGCGTGAGATCATTTTCGATACGGAAACCACGGGCCTCGAATCGAAGCTGGACCGCGTGATTGAAATCGGCGGTATCGA
ACTGATCAATCATTTTCCCACTGGCCGCACGCTGCATCTTTATATCAGCCCGGAGGATCGCAAGGTCCACCCGGATGCGC
TTGCCGTTCACGGCATTACCGATGAGTTTCTGAAGGACAAACCGAAATTCGCAGAAGTCATCGACCAGATCCGTGAATTC
TTCGATGGCGCACGCTGGGTGGCGCATAATGCGACCTTCGATATGGGCTTCATCAATGCGGAATTCGCGCGTCTGGGCAT
TGAGCCGGTTTCCGCCGAGCTGGTGACCGACACGCTCTCACTTGCCCGTCGCAAGAACCCGATGGGGCCGAATTCGCTGG
ATGCGCTTTGCCGGCGTTACGGCATCGACAATTCCCACCGCACCAAACACGGCGCGCTTCTCGACTCCGAACTTCTGGCC
GAAGTCTATATCGAAATGATCGGCGGTCGCCAGACAGCGCTCGGTTTCGGTTCCGCCGCCCGGCAGGAAACGATCATCAT
CGAAGAAGACGTGCCGCTTGCGCCATTGCAACGGCCAAGCGCTCTGCCCTCGAGGCTGGATGCGGACACGATCGCAGCGC
ATGGCAAACTCGTTCTCGGCATGGGCGACAAGGCGATCTGGAACCGCTACCAGAACTAA

Upstream 100 bases:

>100_bases
ATTTTGTCGTCGATTCGGGAAATGGTGTCGAAGCGGCACGGGATCAGGTAAAAGAAATTCTGCAGAAACTAGGCGCTTGA
GTCGCGCCGCGGAGAGATGA

Downstream 100 bases:

>100_bases
AGCCCGCCCATACTTTGAAATGGAAAATCGGCTAAATAAAAACCCGGGTGAAGAACCCGGGTTTTGTTTTGTCTGCAATG
AAAAGCGGTGCGTGCCGTTT

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MREIIFDTETTGLESKLDRVIEIGGIELINHFPTGRTLHLYISPEDRKVHPDALAVHGITDEFLKDKPKFAEVIDQIREF
FDGARWVAHNATFDMGFINAEFARLGIEPVSAELVTDTLSLARRKNPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQTALGFGSAARQETIIIEEDVPLAPLQRPSALPSRLDADTIAAHGKLVLGMGDKAIWNRYQN

Sequences:

>Translated_232_residues
MREIIFDTETTGLESKLDRVIEIGGIELINHFPTGRTLHLYISPEDRKVHPDALAVHGITDEFLKDKPKFAEVIDQIREF
FDGARWVAHNATFDMGFINAEFARLGIEPVSAELVTDTLSLARRKNPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQTALGFGSAARQETIIIEEDVPLAPLQRPSALPSRLDADTIAAHGKLVLGMGDKAIWNRYQN
>Mature_232_residues
MREIIFDTETTGLESKLDRVIEIGGIELINHFPTGRTLHLYISPEDRKVHPDALAVHGITDEFLKDKPKFAEVIDQIREF
FDGARWVAHNATFDMGFINAEFARLGIEPVSAELVTDTLSLARRKNPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLA
EVYIEMIGGRQTALGFGSAARQETIIIEEDVPLAPLQRPSALPSRLDADTIAAHGKLVLGMGDKAIWNRYQN

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=242, Percent_Identity=45.0413223140496, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787941, Length=199, Percent_Identity=29.1457286432161, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25829; Mature: 25829

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIIFDTETTGLESKLDRVIEIGGIELINHFPTGRTLHLYISPEDRKVHPDALAVHGIT
CCCEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEEECCCCCEECCCCEEECCCC
DEFLKDKPKFAEVIDQIREFFDGARWVAHNATFDMGFINAEFARLGIEPVSAELVTDTLS
HHHHCCCCHHHHHHHHHHHHHCCCCEEECCCEEECCCCHHHHHHCCCCCHHHHHHHHHHH
LARRKNPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLAEVYIEMIGGRQTALGFGSAA
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCC
RQETIIIEEDVPLAPLQRPSALPSRLDADTIAAHGKLVLGMGDKAIWNRYQN
CCCEEEEECCCCCCCCCCCCCCCHHCCHHHHHHCCEEEEECCCHHHHHHCCC
>Mature Secondary Structure
MREIIFDTETTGLESKLDRVIEIGGIELINHFPTGRTLHLYISPEDRKVHPDALAVHGIT
CCCEEECCCCCCHHHHHHHHHHCCCCCEECCCCCCCEEEEEECCCCCEECCCCEEECCCC
DEFLKDKPKFAEVIDQIREFFDGARWVAHNATFDMGFINAEFARLGIEPVSAELVTDTLS
HHHHCCCCHHHHHHHHHHHHHCCCCEEECCCEEECCCCHHHHHHCCCCCHHHHHHHHHHH
LARRKNPMGPNSLDALCRRYGIDNSHRTKHGALLDSELLAEVYIEMIGGRQTALGFGSAA
HHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCC
RQETIIIEEDVPLAPLQRPSALPSRLDADTIAAHGKLVLGMGDKAIWNRYQN
CCCEEEEECCCCCCCCCCCCCCCHHCCHHHHHHCCEEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]