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The map label for this gene is glyQ [H]

Identifier: 239618468

GI number: 239618468

Start: 2241257

End: 2242108

Strand: Reverse

Name: glyQ [H]

Synonym: Kole_2109

Alternate gene names: 239618468

Gene position: 2242108-2241257 (Counterclockwise)

Preceding gene: 239618469

Following gene: 239618467

Centisome position: 97.39

GC content: 42.84

Gene sequence:

>852_bases
ATGTACCTGCAAGAGATAATAGCAAAACTTAATGACTATTGGAGTTCTCAAGGGTGTCTTATTGACCAGCCATACGATGT
TGAAATGGGTGCTGGTACCTTTCATCCATCAACCTTTTTACGTTCTCTCGGTAAAAAGCCCTGGAGAGTAGCTTTTGTGC
AACCAAGTCGGAGGCCCACTGATGGAAGATACGGAGAAAATCCAATGAGAACTCAACGATACTTCCAATATCAGGTAATT
ATCAAACCCAGCCCTGAAAACTCACAGGAGCTCTATATAGGTTCACTGGAAGCCCTTGGTATAGATCCCAAAGAGCATGA
TATTCGATTCGTTGAAGACAACTGGGAATCGCCGACTTTGGGTGCCTGGGGTGTTGGCTGGGAAGTATGGCTCGATGGTA
TGGAGGTTACTCAGTTCACATATTTTCAGCAGGTTGGCAGTATAGATGTCGACCTTATATCTCTGGAGATAACCTACGGT
CTTGAGAGAATCGCCATGTATCTCCAGGGTAAGGATAATTTCTTTGATATAGACTGGAATGAACACTTCAAATACGGTGA
TGTGTTCCTTGAAAACGAACGGCAGTTTTCAGCGTATAATTTCGATGTTGCTGATACCGAAATGCTTTTTGAGCTTTATA
GAATGTATACAAAGGAATTTGAAAGGTGCATGGAAGCCAATTTGATTCTTCCAGCCTATGACTACATGATTAAATGTTCT
CACACCTTTAACCTTCTGGATGCCCGAAACGCGATCAGCGTTGCGCAAAGACAAAGTTACATCAAATCCATTCGTGATAT
GGCAAGAGCTGTTGCCAGAGCTTATATTCAGCAGGAGCGTGATAGCGAATGA

Upstream 100 bases:

>100_bases
TATCTTTCCGATGAATTTGAAAATTTGGAATTTGAGCTTCATAATGGCGGGCAACCTTATTACTATTACCTGATAGCTAT
AGAATGAATGGAGGAATGGT

Downstream 100 bases:

>100_bases
GTTCACATAAGGCACTGCTTGAAATCGGGATAGAGGAAATACCTGCCAGTGAAGTGAAAAGTATCGTTTCTCAGATAAAC
GGACGTTTGCCTAATTTATT

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MYLQEIIAKLNDYWSSQGCLIDQPYDVEMGAGTFHPSTFLRSLGKKPWRVAFVQPSRRPTDGRYGENPMRTQRYFQYQVI
IKPSPENSQELYIGSLEALGIDPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQVGSIDVDLISLEITYG
LERIAMYLQGKDNFFDIDWNEHFKYGDVFLENERQFSAYNFDVADTEMLFELYRMYTKEFERCMEANLILPAYDYMIKCS
HTFNLLDARNAISVAQRQSYIKSIRDMARAVARAYIQQERDSE

Sequences:

>Translated_283_residues
MYLQEIIAKLNDYWSSQGCLIDQPYDVEMGAGTFHPSTFLRSLGKKPWRVAFVQPSRRPTDGRYGENPMRTQRYFQYQVI
IKPSPENSQELYIGSLEALGIDPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQVGSIDVDLISLEITYG
LERIAMYLQGKDNFFDIDWNEHFKYGDVFLENERQFSAYNFDVADTEMLFELYRMYTKEFERCMEANLILPAYDYMIKCS
HTFNLLDARNAISVAQRQSYIKSIRDMARAVARAYIQQERDSE
>Mature_283_residues
MYLQEIIAKLNDYWSSQGCLIDQPYDVEMGAGTFHPSTFLRSLGKKPWRVAFVQPSRRPTDGRYGENPMRTQRYFQYQVI
IKPSPENSQELYIGSLEALGIDPKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQVGSIDVDLISLEITYG
LERIAMYLQGKDNFFDIDWNEHFKYGDVFLENERQFSAYNFDVADTEMLFELYRMYTKEFERCMEANLILPAYDYMIKCS
HTFNLLDARNAISVAQRQSYIKSIRDMARAVARAYIQQERDSE

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1789983, Length=279, Percent_Identity=60.2150537634409, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006194
- InterPro:   IPR002310 [H]

Pfam domain/function: PF02091 tRNA-synt_2e [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 33278; Mature: 33278

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLQEIIAKLNDYWSSQGCLIDQPYDVEMGAGTFHPSTFLRSLGKKPWRVAFVQPSRRPT
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
DGRYGENPMRTQRYFQYQVIIKPSPENSQELYIGSLEALGIDPKEHDIRFVEDNWESPTL
CCCCCCCCHHHHEEEEEEEEEECCCCCCCEEEEEEHHEECCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQVGSIDVDLISLEITYGLERIAMYLQGKDNFFDIDWN
CCCCCCHHHEECCCHHHHHHHHHHHCCCCEEEEEEEEHHCHHHHHHHEECCCCEEECCCC
EHFKYGDVFLENERQFSAYNFDVADTEMLFELYRMYTKEFERCMEANLILPAYDYMIKCS
CCCEECCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEC
HTFNLLDARNAISVAQRQSYIKSIRDMARAVARAYIQQERDSE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYLQEIIAKLNDYWSSQGCLIDQPYDVEMGAGTFHPSTFLRSLGKKPWRVAFVQPSRRPT
CCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCC
DGRYGENPMRTQRYFQYQVIIKPSPENSQELYIGSLEALGIDPKEHDIRFVEDNWESPTL
CCCCCCCCHHHHEEEEEEEEEECCCCCCCEEEEEEHHEECCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQVGSIDVDLISLEITYGLERIAMYLQGKDNFFDIDWN
CCCCCCHHHEECCCHHHHHHHHHHHCCCCEEEEEEEEHHCHHHHHHHEECCCCEEECCCC
EHFKYGDVFLENERQFSAYNFDVADTEMLFELYRMYTKEFERCMEANLILPAYDYMIKCS
CCCEECCEEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEEC
HTFNLLDARNAISVAQRQSYIKSIRDMARAVARAYIQQERDSE
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]