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The map label for this gene is argF [H]

Identifier: 239618430

GI number: 239618430

Start: 2197893

End: 2198882

Strand: Direct

Name: argF [H]

Synonym: Kole_2071

Alternate gene names: 239618430

Gene position: 2197893-2198882 (Clockwise)

Preceding gene: 239618429

Following gene: 239618431

Centisome position: 95.47

GC content: 45.86

Gene sequence:

>990_bases
ATGGGAAGCATGCTCAGAGGAAAGCATTTCATCACCACACAGGAATTTAAAAAAGAAGAAATTGATCTCATGCTGGATCT
GGCAGCAGATCTGAAAAGACGCTTTGCTGTTGGCGAGCTCACACCCTGGCTTCTTTACAAAACAGTTTTTATGATCTTCT
TCGATGAAAGCACAAGAACACGTAATTCGATAGAGGCTGGTATAACTCAACTCGGAGGCCACGCGCATTTCTTGAACCCA
AAGGTTATGCAAACAGCCCATGGAGAGGTCGCTAAGGATACCGCTCAGATACTTTCAAGGTATGGCCACGCAATAGCCGT
GAGACATTGTGCATACAAGATAGGAAATGATTACCTCAGAGCCCTCGCAAAGTATTCGGATGTTCCTATTTTGAACCTTC
AGGACGATTTCTATCATCCAATGCAGGTTCTCGCTGATTTAATGACAATACAGGAAAGATTTGGTAAGAACACCAGAGGG
CTGAAAGTGGCCATCACATGGGCGTATGCTGAAAGTCATCTGAAGCCTCTTTCAGTACCACAGTCCCAACTCCTTCTCTT
CCCGCGTTATGGAATGGACGTAACCCTTGCTTACCCGAAGGGATTCGATCTAATGCCGGAGATAGTTGAACAGGCGAAGA
AGAACGCTGAAGAAACAGGCGCGAAATTTGAGATCATCCACGATATGGATGAAGCCTTCAAAGATGCGGATATCGTCATT
CCAAAATCATGGGGCGGCTTCTTTGTTTCCGATGATCCAGAAACCATTATGGCAGAGGTCAGAAAGCACAAAGACTGGAT
CTGTACACCTGAAAGAATGAAACTCGCCAAGAAGCACGCTGTCTACATGCATGCTCTTCCAGCAGATAGAGGAAGAGAAG
TTGTTGATGAAGTCATTGATGGTCCACAGTCAATCGTCATAGACGAAGCAGAAAACCGCCTGCACACCGCAAAAGCTGTT
ATGGCTTTAACCATGGGTGGTAGGCCGTGA

Upstream 100 bases:

>100_bases
CCCAAAGGATCAGGTACCTGTTGATCATCTTGTTAAGGCAGCTGCAATGTATGCTTATTTACCTTTGAAACTTTCAAAAG
AACTTTAAGGAGGGTTAGTT

Downstream 100 bases:

>100_bases
AATATGATCTTGTACTGATTGGCGGGGAGGTCTGCGATGGCGCAGATCTCTATGCTGCCAATTTGTATATTTCCGAAGGA
AAGATAGCGGATATAACTCC

Product: Ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGSMLRGKHFITTQEFKKEEIDLMLDLAADLKRRFAVGELTPWLLYKTVFMIFFDESTRTRNSIEAGITQLGGHAHFLNP
KVMQTAHGEVAKDTAQILSRYGHAIAVRHCAYKIGNDYLRALAKYSDVPILNLQDDFYHPMQVLADLMTIQERFGKNTRG
LKVAITWAYAESHLKPLSVPQSQLLLFPRYGMDVTLAYPKGFDLMPEIVEQAKKNAEETGAKFEIIHDMDEAFKDADIVI
PKSWGGFFVSDDPETIMAEVRKHKDWICTPERMKLAKKHAVYMHALPADRGREVVDEVIDGPQSIVIDEAENRLHTAKAV
MALTMGGRP

Sequences:

>Translated_329_residues
MGSMLRGKHFITTQEFKKEEIDLMLDLAADLKRRFAVGELTPWLLYKTVFMIFFDESTRTRNSIEAGITQLGGHAHFLNP
KVMQTAHGEVAKDTAQILSRYGHAIAVRHCAYKIGNDYLRALAKYSDVPILNLQDDFYHPMQVLADLMTIQERFGKNTRG
LKVAITWAYAESHLKPLSVPQSQLLLFPRYGMDVTLAYPKGFDLMPEIVEQAKKNAEETGAKFEIIHDMDEAFKDADIVI
PKSWGGFFVSDDPETIMAEVRKHKDWICTPERMKLAKKHAVYMHALPADRGREVVDEVIDGPQSIVIDEAENRLHTAKAV
MALTMGGRP
>Mature_328_residues
GSMLRGKHFITTQEFKKEEIDLMLDLAADLKRRFAVGELTPWLLYKTVFMIFFDESTRTRNSIEAGITQLGGHAHFLNPK
VMQTAHGEVAKDTAQILSRYGHAIAVRHCAYKIGNDYLRALAKYSDVPILNLQDDFYHPMQVLADLMTIQERFGKNTRGL
KVAITWAYAESHLKPLSVPQSQLLLFPRYGMDVTLAYPKGFDLMPEIVEQAKKNAEETGAKFEIIHDMDEAFKDADIVIP
KSWGGFFVSDDPETIMAEVRKHKDWICTPERMKLAKKHAVYMHALPADRGREVVDEVIDGPQSIVIDEAENRLHTAKAVM
ALTMGGRP

Specific function: Unknown

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=318, Percent_Identity=34.2767295597484, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI18105007, Length=327, Percent_Identity=25.3822629969419, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI48994908, Length=320, Percent_Identity=40.625, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1786469, Length=344, Percent_Identity=31.3953488372093, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790703, Length=338, Percent_Identity=29.8816568047337, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI2367364, Length=165, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=163, Percent_Identity=30.0613496932515, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322373, Length=334, Percent_Identity=29.940119760479, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6322331, Length=324, Percent_Identity=26.8518518518519, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24642586, Length=333, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37278; Mature: 37146

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSMLRGKHFITTQEFKKEEIDLMLDLAADLKRRFAVGELTPWLLYKTVFMIFFDESTRT
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCC
RNSIEAGITQLGGHAHFLNPKVMQTAHGEVAKDTAQILSRYGHAIAVRHCAYKIGNDYLR
HHHHHHHHHHHCCCEEECCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ALAKYSDVPILNLQDDFYHPMQVLADLMTIQERFGKNTRGLKVAITWAYAESHLKPLSVP
HHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCCC
QSQLLLFPRYGMDVTLAYPKGFDLMPEIVEQAKKNAEETGAKFEIIHDMDEAFKDADIVI
HHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCHHHCCCEEEEHHHHHHHHCCCCEEE
PKSWGGFFVSDDPETIMAEVRKHKDWICTPERMKLAKKHAVYMHALPADRGREVVDEVID
ECCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHC
GPQSIVIDEAENRLHTAKAVMALTMGGRP
CCCEEEEECHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GSMLRGKHFITTQEFKKEEIDLMLDLAADLKRRFAVGELTPWLLYKTVFMIFFDESTRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCCCC
RNSIEAGITQLGGHAHFLNPKVMQTAHGEVAKDTAQILSRYGHAIAVRHCAYKIGNDYLR
HHHHHHHHHHHCCCEEECCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
ALAKYSDVPILNLQDDFYHPMQVLADLMTIQERFGKNTRGLKVAITWAYAESHLKPLSVP
HHHHHCCCCEEECCHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCCC
QSQLLLFPRYGMDVTLAYPKGFDLMPEIVEQAKKNAEETGAKFEIIHDMDEAFKDADIVI
HHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCHHHCCCEEEEHHHHHHHHCCCCEEE
PKSWGGFFVSDDPETIMAEVRKHKDWICTPERMKLAKKHAVYMHALPADRGREVVDEVID
ECCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHC
GPQSIVIDEAENRLHTAKAVMALTMGGRP
CCCEEEEECHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA