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The map label for this gene is xylR [H]

Identifier: 239618336

GI number: 239618336

Start: 2092773

End: 2093999

Strand: Direct

Name: xylR [H]

Synonym: Kole_1973

Alternate gene names: 239618336

Gene position: 2092773-2093999 (Clockwise)

Preceding gene: 239618321

Following gene: 239618337

Centisome position: 90.91

GC content: 40.75

Gene sequence:

>1227_bases
GTGAAGAAAGAAAGTGATGGCGTGAAGAGAAGAGGTTCGAAGCATTTAATTAAGGAAATTAACGAAAAATTGATACTGAA
GACTATTTATGAAAACAAAAAGATTGATAGAGCCTCCATAGCAAAATTTACCGGGCTCAGTCCCGCAGCAGTAACCAAGA
TAACAGCAGAACTAATAAACAGAGGTATGGTACTTGAAGCAGGTTCTGCAGAATCTTCCGGTGGGAGAAAACCTATATTG
CTTTCTCTTAATCCCAAATTTGGCCAGTTTCTTGGTGTGAAAATCGGGGTCGGATATGTTGAATTGGTCATAACCGACTT
TACTTGCACGATTGTTGAAAGCGCCAGATGTGACACAGAGAGTTCAGATCCTGGGACAATAGTTAACGTAATTAAAAATT
GCTGGGAAAAGTGCAGACAAGAAAAACAGTCAATATTACTTGGCATAGGTATCGCTGTGTCCGGTGTTGTTGATTCAAAA
GAAGGAATAGTACGGGATTCATTTTTGTTAGGCTGGAGAGATGTACCGATTGCTTCTTTATTGAAGGAAGTATTTAAATG
TGAAGTTCTTGTGATGAACGATGTGGATTCATTCGCGATGAGTCATTTGTGGTTGGGAAAAGCGAAAGACCACTCTAACA
CCGTTGTGATTACGCTTGGTGTTGGAATCGGTGGTGCCCTGATTATAGACGGGAAAATTCACAATGCAAAGGGCGGTGTC
GGGGAGATTGGCCATATGACTGTCGTCAAAGACGGTGCAAAATGTACGTGCGGAAGCAATGGCTGCCTTGAAGCTGAGGC
TTCGTTCGGGGCATTGGCAAAAAAAATAAGCTCCATTACCGAAAGCAAAAAACTTAAAGAGCTATACAAGTCAGTTAAAC
AGTCAGAAAGCTCCGAGATAGAGTATTTAAGGGAGGCGTTGAAAAGGGATAGAAAGGCGTTTAACCATGTTTTTGAAGAA
TATGCTGTGCTTGTTGGTATAGCCCTGAAGAACATTATAAATATGTTGGCTCCAGATTATCTGCTTATTGGTGGCGAAGC
CCTCGAATTTCAGGAAAAATTTCTCAACAAAGCTATCCAATATGCCCAAAAAAATGCATTTGGGAAATTGGGGGAAAAGG
TTATGTTTAATGTTGACGACCTGGGAGAAGTAGCATGGAACCTTGGGGTAATTTTTGTACTTATGGATAATCTTTTTCTC
ACTACTTCTCACAATGAAAGTCGGTGA

Upstream 100 bases:

>100_bases
TAATCATAACCGTTCATATCTAGTCTTAACTGACAATATTTCCAATCCAGTGAGTTTTGGTATATGCAATTTGAGTTTTA
TAATGTAGATAGTTTATTCA

Downstream 100 bases:

>100_bases
ACTCAGTGAAAAGAAAAGGAGATTTAAAATACCTTATCTTCTTTTTAACTCCAAGCTTGATATTCCTATTTCTTTTCCAG
ATTCTTCCTATAACCTATTC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKKESDGVKRRGSKHLIKEINEKLILKTIYENKKIDRASIAKFTGLSPAAVTKITAELINRGMVLEAGSAESSGGRKPIL
LSLNPKFGQFLGVKIGVGYVELVITDFTCTIVESARCDTESSDPGTIVNVIKNCWEKCRQEKQSILLGIGIAVSGVVDSK
EGIVRDSFLLGWRDVPIASLLKEVFKCEVLVMNDVDSFAMSHLWLGKAKDHSNTVVITLGVGIGGALIIDGKIHNAKGGV
GEIGHMTVVKDGAKCTCGSNGCLEAEASFGALAKKISSITESKKLKELYKSVKQSESSEIEYLREALKRDRKAFNHVFEE
YAVLVGIALKNIINMLAPDYLLIGGEALEFQEKFLNKAIQYAQKNAFGKLGEKVMFNVDDLGEVAWNLGVIFVLMDNLFL
TTSHNESR

Sequences:

>Translated_408_residues
MKKESDGVKRRGSKHLIKEINEKLILKTIYENKKIDRASIAKFTGLSPAAVTKITAELINRGMVLEAGSAESSGGRKPIL
LSLNPKFGQFLGVKIGVGYVELVITDFTCTIVESARCDTESSDPGTIVNVIKNCWEKCRQEKQSILLGIGIAVSGVVDSK
EGIVRDSFLLGWRDVPIASLLKEVFKCEVLVMNDVDSFAMSHLWLGKAKDHSNTVVITLGVGIGGALIIDGKIHNAKGGV
GEIGHMTVVKDGAKCTCGSNGCLEAEASFGALAKKISSITESKKLKELYKSVKQSESSEIEYLREALKRDRKAFNHVFEE
YAVLVGIALKNIINMLAPDYLLIGGEALEFQEKFLNKAIQYAQKNAFGKLGEKVMFNVDDLGEVAWNLGVIFVLMDNLFL
TTSHNESR
>Mature_408_residues
MKKESDGVKRRGSKHLIKEINEKLILKTIYENKKIDRASIAKFTGLSPAAVTKITAELINRGMVLEAGSAESSGGRKPIL
LSLNPKFGQFLGVKIGVGYVELVITDFTCTIVESARCDTESSDPGTIVNVIKNCWEKCRQEKQSILLGIGIAVSGVVDSK
EGIVRDSFLLGWRDVPIASLLKEVFKCEVLVMNDVDSFAMSHLWLGKAKDHSNTVVITLGVGIGGALIIDGKIHNAKGGV
GEIGHMTVVKDGAKCTCGSNGCLEAEASFGALAKKISSITESKKLKELYKSVKQSESSEIEYLREALKRDRKAFNHVFEE
YAVLVGIALKNIINMLAPDYLLIGGEALEFQEKFLNKAIQYAQKNAFGKLGEKVMFNVDDLGEVAWNLGVIFVLMDNLFL
TTSHNESR

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=203, Percent_Identity=30.0492610837438, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI298566315, Length=203, Percent_Identity=30.0492610837438, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4885285, Length=203, Percent_Identity=30.0492610837438, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI298566325, Length=203, Percent_Identity=30.0492610837438, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1786891, Length=353, Percent_Identity=26.628895184136, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082127, Length=356, Percent_Identity=23.876404494382, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787878, Length=337, Percent_Identity=24.6290801186944, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1787363, Length=208, Percent_Identity=25.9615384615385, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44548; Mature: 44548

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKESDGVKRRGSKHLIKEINEKLILKTIYENKKIDRASIAKFTGLSPAAVTKITAELIN
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
RGMVLEAGSAESSGGRKPILLSLNPKFGQFLGVKIGVGYVELVITDFTCTIVESARCDTE
CCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEEEEHHHEEEHHHHCCCCC
SSDPGTIVNVIKNCWEKCRQEKQSILLGIGIAVSGVVDSKEGIVRDSFLLGWRDVPIASL
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECHHEECCCCCCCCCCHHHHEECCCCCCHHHH
LKEVFKCEVLVMNDVDSFAMSHLWLGKAKDHSNTVVITLGVGIGGALIIDGKIHNAKGGV
HHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECCEEECCCCCC
GEIGHMTVVKDGAKCTCGSNGCLEAEASFGALAKKISSITESKKLKELYKSVKQSESSEI
CCCCCEEEEECCCEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EYLREALKRDRKAFNHVFEEYAVLVGIALKNIINMLAPDYLLIGGEALEFQEKFLNKAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
YAQKNAFGKLGEKVMFNVDDLGEVAWNLGVIFVLMDNLFLTTSHNESR
HHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC
>Mature Secondary Structure
MKKESDGVKRRGSKHLIKEINEKLILKTIYENKKIDRASIAKFTGLSPAAVTKITAELIN
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHC
RGMVLEAGSAESSGGRKPILLSLNPKFGQFLGVKIGVGYVELVITDFTCTIVESARCDTE
CCEEEECCCCCCCCCCCCEEEEECCCCCCEEEEEECCCEEEEEEEHHHEEEHHHHCCCCC
SSDPGTIVNVIKNCWEKCRQEKQSILLGIGIAVSGVVDSKEGIVRDSFLLGWRDVPIASL
CCCCHHHHHHHHHHHHHHHHHHHHEEEEECHHEECCCCCCCCCCHHHHEECCCCCCHHHH
LKEVFKCEVLVMNDVDSFAMSHLWLGKAKDHSNTVVITLGVGIGGALIIDGKIHNAKGGV
HHHHHHCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEECCEEECCCCCC
GEIGHMTVVKDGAKCTCGSNGCLEAEASFGALAKKISSITESKKLKELYKSVKQSESSEI
CCCCCEEEEECCCEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
EYLREALKRDRKAFNHVFEEYAVLVGIALKNIINMLAPDYLLIGGEALEFQEKFLNKAIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHH
YAQKNAFGKLGEKVMFNVDDLGEVAWNLGVIFVLMDNLFLTTSHNESR
HHHHHHHHHCCHHEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8920183 [H]