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The map label for this gene is yuxL [H]

Identifier: 239618185

GI number: 239618185

Start: 1946613

End: 1948568

Strand: Direct

Name: yuxL [H]

Synonym: Kole_1821

Alternate gene names: 239618185

Gene position: 1946613-1948568 (Clockwise)

Preceding gene: 239618183

Following gene: 239618186

Centisome position: 84.56

GC content: 44.33

Gene sequence:

>1956_bases
GTGGACAGGATTTCTTTGACTGATTTGTATCGTTATGTGAGTTTGGGAAATATAGAGTTTTTGCCGGAGGGAAAGAAATT
CATCTTTGTCAGGAAAAGGATGGATAAGAAGCAAAATAAGTATTACAGTGATATCTGGATCATGGATGTTTCAGGGAGAA
ATCGCCGACAGCTCACATTTGGAAAATTTGATTCTTCTCCAAAAATAAGCCCGGACGGAAAACTTCTAGCATTTACTTCT
AAACGTGAGAAGGATTCACAGGGTACAGAACTGTACATCCTTCCCCTTGACGGCGGTGAATCAAAGTTAGTGAAAACCAT
CGAAGGTGGTGTCCAATCCCTGGAGTGGATTGATAATACAAAACTCGCTTTCGTTTCAGCTGTTAGACCTGACGGAAAAG
CCCCCGAAAAAGAACCACCGGAAAAAAAGGTTTATGAAATCGAGAGGATCCCTTTCCTTGGAAACGGTGCAGGGTTTACG
GATGGAAGATATGGGCACGCTTTTTTGCTTGATATAAATTCCGGGAAATTAGAACGGCTCACCGAAGGCGAAACGCATGT
AAGGGGAGTGTCACCTTCGCCAGATGGGAGAAAACTTGCGGTTGTGATGCTCGATAATCCTGAACAGAGACCTATATGGG
CTTCACTGTACGTAATCGACCTAAAAACCCGTGACAGGATACGGTTGTTCAACGATAAGGTTTCGGTAATGTATGCCGAA
TGGAAGGATAACGATAATCTGTACGCTCTCATAACAGACTTCAAAAAGGGATTTGCTACAAACCCCAAAGTAGCGATTGC
GCGAGTACCGACTAAAAGGACAAGAACCATCTTTGATGGTGATCTTTCTTTCTTCAATAGTTTAAACAGCGATGTGAGAG
GCGTTGGAGGTAGGCAGATTAGAGTTCACAATGGTTCTTTATATTTCATCACCACAGACGGGCCAAAGGCTGTCATCAAG
TCCGTTGACAATAAAGGCAAGCTTAGTACTGTTCTCGATGTTAACGCCAGCATAGATTGTTTTGACATTGCGCCTGACGG
GACTATTGTTTTCACGATGATGAATCCCACCTATCCTCTGGAGATTTACAAGAGCAAAAAGGGAAAAATCAGGAAGCTTA
CGTCATTCAATGGCTGGATTAGAAAGTATCGGTTGTCCGAACCGGAAGGGTTTAAGGTAGAAGCATCGGATGGGAAAGTT
ATCGATGCATGGATAATGAAACCCGTGGAATTCGAAGAAGGAAAGAAATATCCTACTATTCTTGAGATTCACGGCGGGCC
AAAGACAGCCTACGGATACGGCTTCATCCATGAATTCCAGCTGCTTGCTGCTTCCGGTTATGCCGTTCTTTTCTGTAATC
CGCGGGGAAGTGACGGTTATGGTTCGGAGTTCGCCGATATACGCGGACATTACGGTGAAAGGGACTTTCAGGATATCATG
GAGGTTGTGGAGTACGCTGTAAATAACTTCGATTTTGTGGACGCCGATCGGCTTGGGGTAACAGGCGGTTCTTATGGGGG
CTTCATGACCAATTGGATTGTAGGGCATACCGATATTTTCAAAGCTGCGGTAAGCCAGAGGTCAATTTCTAACTTTATAT
CTTTCTATGGAACCACGGATATCGGCTATTTCTTTGCTGAAGATCAAATAGGCGGCAATTTCTGGGAAAATCTCGAAGGG
TACATCAGACAATCTCCCCTTTACTATGCTCCGAATGTGGAAACACCGTTGTTGCTCATCCATTCTCTGGAAGATTACCG
CTGTTGGGTACCTGAAGCCATGCAATTTTTTACTGTTCTAAGAAGGCTGGGCAAAGAAGCAAAAATGGTTCTCTTCCCGA
AGGAGAACCACGAGCTTTCGAGAAGTGGGTTACCCGTTCACAGGGAAAAAAGATTGAGAGCTATATTGGATTGGTTTGAA
TCGCACTTGAAGGTTCGCAAGGGGGATACTGAGTGA

Upstream 100 bases:

>100_bases
CTTTGTATTGCCAGATATAGATTCGAAATGATATGAAAGTTCTTATAAAGGAAGGTCATTTGGTAGAATTGAATAAAGCG
AATGAGGAGGGATAATAATC

Downstream 100 bases:

>100_bases
TAATCAGGGAAGCCAGACCGGAAGATAACGCTAAACTTCTCGAAATTGAACGCACTTCAGCTCAAGAGGGGAATGTTTGG
TTTACCTCGAATCGAGAAGA

Product: peptidase S9 prolyl oligopeptidase active site domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MDRISLTDLYRYVSLGNIEFLPEGKKFIFVRKRMDKKQNKYYSDIWIMDVSGRNRRQLTFGKFDSSPKISPDGKLLAFTS
KREKDSQGTELYILPLDGGESKLVKTIEGGVQSLEWIDNTKLAFVSAVRPDGKAPEKEPPEKKVYEIERIPFLGNGAGFT
DGRYGHAFLLDINSGKLERLTEGETHVRGVSPSPDGRKLAVVMLDNPEQRPIWASLYVIDLKTRDRIRLFNDKVSVMYAE
WKDNDNLYALITDFKKGFATNPKVAIARVPTKRTRTIFDGDLSFFNSLNSDVRGVGGRQIRVHNGSLYFITTDGPKAVIK
SVDNKGKLSTVLDVNASIDCFDIAPDGTIVFTMMNPTYPLEIYKSKKGKIRKLTSFNGWIRKYRLSEPEGFKVEASDGKV
IDAWIMKPVEFEEGKKYPTILEIHGGPKTAYGYGFIHEFQLLAASGYAVLFCNPRGSDGYGSEFADIRGHYGERDFQDIM
EVVEYAVNNFDFVDADRLGVTGGSYGGFMTNWIVGHTDIFKAAVSQRSISNFISFYGTTDIGYFFAEDQIGGNFWENLEG
YIRQSPLYYAPNVETPLLLIHSLEDYRCWVPEAMQFFTVLRRLGKEAKMVLFPKENHELSRSGLPVHREKRLRAILDWFE
SHLKVRKGDTE

Sequences:

>Translated_651_residues
MDRISLTDLYRYVSLGNIEFLPEGKKFIFVRKRMDKKQNKYYSDIWIMDVSGRNRRQLTFGKFDSSPKISPDGKLLAFTS
KREKDSQGTELYILPLDGGESKLVKTIEGGVQSLEWIDNTKLAFVSAVRPDGKAPEKEPPEKKVYEIERIPFLGNGAGFT
DGRYGHAFLLDINSGKLERLTEGETHVRGVSPSPDGRKLAVVMLDNPEQRPIWASLYVIDLKTRDRIRLFNDKVSVMYAE
WKDNDNLYALITDFKKGFATNPKVAIARVPTKRTRTIFDGDLSFFNSLNSDVRGVGGRQIRVHNGSLYFITTDGPKAVIK
SVDNKGKLSTVLDVNASIDCFDIAPDGTIVFTMMNPTYPLEIYKSKKGKIRKLTSFNGWIRKYRLSEPEGFKVEASDGKV
IDAWIMKPVEFEEGKKYPTILEIHGGPKTAYGYGFIHEFQLLAASGYAVLFCNPRGSDGYGSEFADIRGHYGERDFQDIM
EVVEYAVNNFDFVDADRLGVTGGSYGGFMTNWIVGHTDIFKAAVSQRSISNFISFYGTTDIGYFFAEDQIGGNFWENLEG
YIRQSPLYYAPNVETPLLLIHSLEDYRCWVPEAMQFFTVLRRLGKEAKMVLFPKENHELSRSGLPVHREKRLRAILDWFE
SHLKVRKGDTE
>Mature_651_residues
MDRISLTDLYRYVSLGNIEFLPEGKKFIFVRKRMDKKQNKYYSDIWIMDVSGRNRRQLTFGKFDSSPKISPDGKLLAFTS
KREKDSQGTELYILPLDGGESKLVKTIEGGVQSLEWIDNTKLAFVSAVRPDGKAPEKEPPEKKVYEIERIPFLGNGAGFT
DGRYGHAFLLDINSGKLERLTEGETHVRGVSPSPDGRKLAVVMLDNPEQRPIWASLYVIDLKTRDRIRLFNDKVSVMYAE
WKDNDNLYALITDFKKGFATNPKVAIARVPTKRTRTIFDGDLSFFNSLNSDVRGVGGRQIRVHNGSLYFITTDGPKAVIK
SVDNKGKLSTVLDVNASIDCFDIAPDGTIVFTMMNPTYPLEIYKSKKGKIRKLTSFNGWIRKYRLSEPEGFKVEASDGKV
IDAWIMKPVEFEEGKKYPTILEIHGGPKTAYGYGFIHEFQLLAASGYAVLFCNPRGSDGYGSEFADIRGHYGERDFQDIM
EVVEYAVNNFDFVDADRLGVTGGSYGGFMTNWIVGHTDIFKAAVSQRSISNFISFYGTTDIGYFFAEDQIGGNFWENLEG
YIRQSPLYYAPNVETPLLLIHSLEDYRCWVPEAMQFFTVLRRLGKEAKMVLFPKENHELSRSGLPVHREKRLRAILDWFE
SHLKVRKGDTE

Specific function: Unknown

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9B family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=253, Percent_Identity=28.8537549407115, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI37577089, Length=271, Percent_Identity=29.1512915129151, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI18450280, Length=271, Percent_Identity=29.1512915129151, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI194394146, Length=249, Percent_Identity=26.5060240963855, Blast_Score=84, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25149159, Length=257, Percent_Identity=28.0155642023346, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144537, Length=297, Percent_Identity=26.5993265993266, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144540, Length=297, Percent_Identity=26.5993265993266, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17552908, Length=293, Percent_Identity=26.6211604095563, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17550672, Length=248, Percent_Identity=25.8064516129032, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17508019, Length=242, Percent_Identity=26.4462809917355, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508017, Length=242, Percent_Identity=26.4462809917355, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144543, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551969, Length=242, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550825, Length=242, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI45553511, Length=242, Percent_Identity=31.8181818181818, Blast_Score=107, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24582257, Length=233, Percent_Identity=28.3261802575107, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011659
- InterPro:   IPR001375 [H]

Pfam domain/function: PF07676 PD40; PF00326 Peptidase_S9 [H]

EC number: NA

Molecular weight: Translated: 73978; Mature: 73978

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRISLTDLYRYVSLGNIEFLPEGKKFIFVRKRMDKKQNKYYSDIWIMDVSGRNRRQLTF
CCCCCHHHHHHHHHCCCEEECCCCCEEEEEEHHHCHHCCCEEEEEEEEECCCCCCEEEEE
GKFDSSPKISPDGKLLAFTSKREKDSQGTELYILPLDGGESKLVKTIEGGVQSLEWIDNT
ECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
KLAFVSAVRPDGKAPEKEPPEKKVYEIERIPFLGNGAGFTDGRYGHAFLLDINSGKLERL
CEEEEEEECCCCCCCCCCCCCCCCEEEECCCEECCCCCCCCCCCCEEEEEECCCCCCHHC
TEGETHVRGVSPSPDGRKLAVVMLDNPEQRPIWASLYVIDLKTRDRIRLFNDKVSVMYAE
CCCCCEEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCCEEEECCCEEEEEEE
WKDNDNLYALITDFKKGFATNPKVAIARVPTKRTRTIFDGDLSFFNSLNSDVRGVGGRQI
ECCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCEEECCCHHHHHHCCCHHCCCCCCEE
RVHNGSLYFITTDGPKAVIKSVDNKGKLSTVLDVNASIDCFDIAPDGTIVFTMMNPTYPL
EEECCEEEEEECCCHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEECCCCCE
EIYKSKKGKIRKLTSFNGWIRKYRLSEPEGFKVEASDGKVIDAWIMKPVEFEEGKKYPTI
EEEECCCCCEEEECCCCHHHHEEECCCCCCCEEECCCCCEEEHHHCCCEECCCCCCCCEE
LEIHGGPKTAYGYGFIHEFQLLAASGYAVLFCNPRGSDGYGSEFADIRGHYGERDFQDIM
EEECCCCCCCCCCCHHEEEEEEEECCEEEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHH
EVVEYAVNNFDFVDADRLGVTGGSYGGFMTNWIVGHTDIFKAAVSQRSISNFISFYGTTD
HHHHHHHCCCCEECCCCCCCCCCCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCC
IGYFFAEDQIGGNFWENLEGYIRQSPLYYAPNVETPLLLIHSLEDYRCWVPEAMQFFTVL
CEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
RRLGKEAKMVLFPKENHELSRSGLPVHREKRLRAILDWFESHLKVRKGDTE
HHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCC
>Mature Secondary Structure
MDRISLTDLYRYVSLGNIEFLPEGKKFIFVRKRMDKKQNKYYSDIWIMDVSGRNRRQLTF
CCCCCHHHHHHHHHCCCEEECCCCCEEEEEEHHHCHHCCCEEEEEEEEECCCCCCEEEEE
GKFDSSPKISPDGKLLAFTSKREKDSQGTELYILPLDGGESKLVKTIEGGVQSLEWIDNT
ECCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
KLAFVSAVRPDGKAPEKEPPEKKVYEIERIPFLGNGAGFTDGRYGHAFLLDINSGKLERL
CEEEEEEECCCCCCCCCCCCCCCCEEEECCCEECCCCCCCCCCCCEEEEEECCCCCCHHC
TEGETHVRGVSPSPDGRKLAVVMLDNPEQRPIWASLYVIDLKTRDRIRLFNDKVSVMYAE
CCCCCEEECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCCEEEECCCEEEEEEE
WKDNDNLYALITDFKKGFATNPKVAIARVPTKRTRTIFDGDLSFFNSLNSDVRGVGGRQI
ECCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCEEECCCHHHHHHCCCHHCCCCCCEE
RVHNGSLYFITTDGPKAVIKSVDNKGKLSTVLDVNASIDCFDIAPDGTIVFTMMNPTYPL
EEECCEEEEEECCCHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCEEEEEEECCCCCE
EIYKSKKGKIRKLTSFNGWIRKYRLSEPEGFKVEASDGKVIDAWIMKPVEFEEGKKYPTI
EEEECCCCCEEEECCCCHHHHEEECCCCCCCEEECCCCCEEEHHHCCCEECCCCCCCCEE
LEIHGGPKTAYGYGFIHEFQLLAASGYAVLFCNPRGSDGYGSEFADIRGHYGERDFQDIM
EEECCCCCCCCCCCHHEEEEEEEECCEEEEEECCCCCCCCCCCHHHHCCCCCCCHHHHHH
EVVEYAVNNFDFVDADRLGVTGGSYGGFMTNWIVGHTDIFKAAVSQRSISNFISFYGTTD
HHHHHHHCCCCEECCCCCCCCCCCCCCHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCC
IGYFFAEDQIGGNFWENLEGYIRQSPLYYAPNVETPLLLIHSLEDYRCWVPEAMQFFTVL
CEEEEEECCCCCHHHHHHHHHHHCCCEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHH
RRLGKEAKMVLFPKENHELSRSGLPVHREKRLRAILDWFESHLKVRKGDTE
HHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 3098560 [H]