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The map label for this gene is yghZ [H]

Identifier: 239618047

GI number: 239618047

Start: 1809685

End: 1810647

Strand: Direct

Name: yghZ [H]

Synonym: Kole_1676

Alternate gene names: 239618047

Gene position: 1809685-1810647 (Clockwise)

Preceding gene: 239618046

Following gene: 239618048

Centisome position: 78.61

GC content: 42.99

Gene sequence:

>963_bases
ATGGAATATAGAAAGGTTGGAAAATGGGGAATTAGAATCAGTGAACTTTCTCTTGGTTCTTGGTTGACCTTTGGAAACCA
GCTTGACATTCGTGGAGCTAAAGAGTGCGTAAGGGAAGCTTTTAAAAATGGAATTAACTTCTTTGACACGGCTGAGGTGT
ATGCCAATGGCATGGCAGAATCAATGCTTGGAGAAGTTTTGAAAGAGTTCAGAAGAGAGGACATAGTGGTTTCGACGAAG
ATTTTTTGGGGTGGGGAAGGACCGAATAAGAAAGGGTTGTCCCGCAAACACCTGCTGGAAGGAACCTGGGGATCTTTGAA
ACGACTTCAGCTGGATTATGTAGATATTTTATATTGCCATAGACCAGATCCAGAAACCCCTATCGAAGAAACCGTTCTCG
CAATGGATTATCTTGTAAGAAACGGCCTTACTCTTTACTGGGGAACGTCCGAATGGAGTTACGAAGAGCTTGAAGCAGCT
CATAAGGTCTGTAAAGAGCTCAACTGCATTCCTCCGATTGTAGAGCAGCCGCAGTATAATATGCTCGTTAGGGAAAAGGT
TGAGAAAGAATACGCGCCTATTTACGAGAAATACGGCATTGGTTTGACAACGTGGAGTCCCCTTGCATCGGGGGTATTAA
CCGGAAAATATAACAATGGTATCCCCGAAGGGAGTAGATTGGCGAGGTTTTCCTGGTTGAGAAAGAGTCTTGAAGAGAAG
GGACTACTCAGTGATGAGACACTTTCAAAGGTTCGAAAACTGGAAAAGATTGCAAAGTCACTTGATGCTAAATTGTCTCA
ACTGGCTTTAGCCTGGTGTTTAAAGAATCCTCATGTCAGCAGTGTAATACTGGGAGTCAGCAGTGTGAACCAGTTGCATG
AGAATATGGCAGCTCTTGAGGTGAAAAGCAAATTAACCGATGATGTGATGAATGAGATAGAGAATATTCTTTCAGGCAAA
TAA

Upstream 100 bases:

>100_bases
GGAGACCGAGGTGAATCTTCTGTAAAAGTACTCTTTTGATTTTTATTCTACTTAACGTATAATAATATATGAGAGGCAAA
TACCAAAAGGAGGAGAAAGC

Downstream 100 bases:

>100_bases
CGAAAAAGGGGGCTAAACCAGCCCCCTTTTTAGGTCGGTGGTGTTGAGAACATGAAAGAAGAAATCATGGAATTCATCGA
GAAGACGGTTTATGAGTATG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MEYRKVGKWGIRISELSLGSWLTFGNQLDIRGAKECVREAFKNGINFFDTAEVYANGMAESMLGEVLKEFRREDIVVSTK
IFWGGEGPNKKGLSRKHLLEGTWGSLKRLQLDYVDILYCHRPDPETPIEETVLAMDYLVRNGLTLYWGTSEWSYEELEAA
HKVCKELNCIPPIVEQPQYNMLVREKVEKEYAPIYEKYGIGLTTWSPLASGVLTGKYNNGIPEGSRLARFSWLRKSLEEK
GLLSDETLSKVRKLEKIAKSLDAKLSQLALAWCLKNPHVSSVILGVSSVNQLHENMAALEVKSKLTDDVMNEIENILSGK

Sequences:

>Translated_320_residues
MEYRKVGKWGIRISELSLGSWLTFGNQLDIRGAKECVREAFKNGINFFDTAEVYANGMAESMLGEVLKEFRREDIVVSTK
IFWGGEGPNKKGLSRKHLLEGTWGSLKRLQLDYVDILYCHRPDPETPIEETVLAMDYLVRNGLTLYWGTSEWSYEELEAA
HKVCKELNCIPPIVEQPQYNMLVREKVEKEYAPIYEKYGIGLTTWSPLASGVLTGKYNNGIPEGSRLARFSWLRKSLEEK
GLLSDETLSKVRKLEKIAKSLDAKLSQLALAWCLKNPHVSSVILGVSSVNQLHENMAALEVKSKLTDDVMNEIENILSGK
>Mature_320_residues
MEYRKVGKWGIRISELSLGSWLTFGNQLDIRGAKECVREAFKNGINFFDTAEVYANGMAESMLGEVLKEFRREDIVVSTK
IFWGGEGPNKKGLSRKHLLEGTWGSLKRLQLDYVDILYCHRPDPETPIEETVLAMDYLVRNGLTLYWGTSEWSYEELEAA
HKVCKELNCIPPIVEQPQYNMLVREKVEKEYAPIYEKYGIGLTTWSPLASGVLTGKYNNGIPEGSRLARFSWLRKSLEEK
GLLSDETLSKVRKLEKIAKSLDAKLSQLALAWCLKNPHVSSVILGVSSVNQLHENMAALEVKSKLTDDVMNEIENILSGK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=325, Percent_Identity=48.6153846153846, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=48.6068111455108, Blast_Score=324, Evalue=7e-89,
Organism=Homo sapiens, GI27436964, Length=325, Percent_Identity=47.6923076923077, Blast_Score=323, Evalue=1e-88,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=47.6923076923077, Blast_Score=321, Evalue=6e-88,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=47.3846153846154, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=45.3703703703704, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI223718702, Length=295, Percent_Identity=31.1864406779661, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI41152114, Length=298, Percent_Identity=31.2080536912752, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI41327764, Length=295, Percent_Identity=31.864406779661, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=37.5, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI87081735, Length=317, Percent_Identity=36.2776025236593, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=30.2857142857143, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=29.3939393939394, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788081, Length=292, Percent_Identity=23.6301369863014, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17550248, Length=233, Percent_Identity=25.3218884120172, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=325, Percent_Identity=29.5384615384615, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=329, Percent_Identity=28.2674772036474, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=27.7027027027027, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6319951, Length=222, Percent_Identity=28.8288288288288, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=31.3725490196078, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=35.2941176470588, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24640980, Length=340, Percent_Identity=35.2941176470588, Blast_Score=221, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24646155, Length=308, Percent_Identity=27.9220779220779, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646159, Length=309, Percent_Identity=25.2427184466019, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36252; Mature: 36252

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRKVGKWGIRISELSLGSWLTFGNQLDIRGAKECVREAFKNGINFFDTAEVYANGMAE
CCCCHHCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SMLGEVLKEFRREDIVVSTKIFWGGEGPNKKGLSRKHLLEGTWGSLKRLQLDYVDILYCH
HHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHEEEEEEE
RPDPETPIEETVLAMDYLVRNGLTLYWGTSEWSYEELEAAHKVCKELNCIPPIVEQPQYN
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHH
MLVREKVEKEYAPIYEKYGIGLTTWSPLASGVLTGKYNNGIPEGSRLARFSWLRKSLEEK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHC
GLLSDETLSKVRKLEKIAKSLDAKLSQLALAWCLKNPHVSSVILGVSSVNQLHENMAALE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VKSKLTDDVMNEIENILSGK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEYRKVGKWGIRISELSLGSWLTFGNQLDIRGAKECVREAFKNGINFFDTAEVYANGMAE
CCCCHHCCCCCEEEEECCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
SMLGEVLKEFRREDIVVSTKIFWGGEGPNKKGLSRKHLLEGTWGSLKRLQLDYVDILYCH
HHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCCCHHHHHCCCHHHHHHHHHHHEEEEEEE
RPDPETPIEETVLAMDYLVRNGLTLYWGTSEWSYEELEAAHKVCKELNCIPPIVEQPQYN
CCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHH
MLVREKVEKEYAPIYEKYGIGLTTWSPLASGVLTGKYNNGIPEGSRLARFSWLRKSLEEK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHHHHC
GLLSDETLSKVRKLEKIAKSLDAKLSQLALAWCLKNPHVSSVILGVSSVNQLHENMAALE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
VKSKLTDDVMNEIENILSGK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]