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The map label for this gene is panC [H]

Identifier: 239618020

GI number: 239618020

Start: 1776909

End: 1777775

Strand: Direct

Name: panC [H]

Synonym: Kole_1649

Alternate gene names: 239618020

Gene position: 1776909-1777775 (Clockwise)

Preceding gene: 239618019

Following gene: 239618032

Centisome position: 77.19

GC content: 44.87

Gene sequence:

>867_bases
GTGCGAGTTATTGAAAGCCCAAAGGAAATGCAAAAAATTGCCATAGATATTGAGAGAGAAGAAAAAAGCCATGGGTTTGT
ACCTACGATGGGGTATCTGCATGAGGGGCATCTCTCCCTCGTCAGGCAGGCAAGAATGGATAATGTTGTTGTTACGGTGA
GCATTTTTGTAAATCCCACACAGTTTGGGCCCAACGAGGATTACGATAGATATCCCAGAGATGAGGAAAGGGATCTTTCT
TTGTTGAGAGATCTTGATGTTGACTATGTTTTTATTCCGAAGGTTGAAGATATGTATCCGGATAATTACTCCACATACGT
TATTGTTGAAGATCTGACGGATGTTCTTTGTGGTGCCAGGCGTCCTGGACATTTTAAGGGGGTCGCCACGATAGTGGCAA
AGCTGTTCAATATAGTCAGACCCACGAAAGCCTATTTTGGCCAAAAAGATGCACAGCAGTTCAGAGTGCTCAAGCGAATG
GCACGGGATCTGAATTTTCCGGTAGAACTGGTGGAAATGCCTATCGTCCGGGAAAAGGATGGCCTTGCTATGAGTTCAAG
AAATGTGTATCTATCTCCCGAGGAAAGACAGGAGGCCTTGCTCATACACCAGGCGTTGCTCGCCGGACGAAAGCTCATAG
AGGCGGGAGAGTTTGACCCTGAAAAGGTTAAATCGGAGATGTTAGCAATCTTGAGCAAAGGCCAGCGAATAAAGTCTGAC
TACGTCGAGATTGTTGATGAGGAGACGCTGTACCCTATCGAAAATCTCGAAGATACCACTAACGGGAAGGTTATTTTAGC
CATCGCCGCATTCGTTGGGAAAGCCCGACTTATAGATAATGAAATTGTAAATCTAAAAATGAAGTAG

Upstream 100 bases:

>100_bases
GATCCTTTGTATGAATCTGCGATGAGAAAGGGATTCGATACAGTTGCATGGCATATAGAAATGGTTCTTAAACTTCATTG
AACACGGGAGGTTGGAAAAA

Downstream 100 bases:

>100_bases
TTCTTTCTGGAAGTTCAGGAGATAATCCATAAGAACGAGGCCGGCTTCCGGATTTTTCTTTATCGCTGTATTGAGAAAGG
TATCTTTGTCTAAGACTACT

Product: pantoate/beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MRVIESPKEMQKIAIDIEREEKSHGFVPTMGYLHEGHLSLVRQARMDNVVVTVSIFVNPTQFGPNEDYDRYPRDEERDLS
LLRDLDVDYVFIPKVEDMYPDNYSTYVIVEDLTDVLCGARRPGHFKGVATIVAKLFNIVRPTKAYFGQKDAQQFRVLKRM
ARDLNFPVELVEMPIVREKDGLAMSSRNVYLSPEERQEALLIHQALLAGRKLIEAGEFDPEKVKSEMLAILSKGQRIKSD
YVEIVDEETLYPIENLEDTTNGKVILAIAAFVGKARLIDNEIVNLKMK

Sequences:

>Translated_288_residues
MRVIESPKEMQKIAIDIEREEKSHGFVPTMGYLHEGHLSLVRQARMDNVVVTVSIFVNPTQFGPNEDYDRYPRDEERDLS
LLRDLDVDYVFIPKVEDMYPDNYSTYVIVEDLTDVLCGARRPGHFKGVATIVAKLFNIVRPTKAYFGQKDAQQFRVLKRM
ARDLNFPVELVEMPIVREKDGLAMSSRNVYLSPEERQEALLIHQALLAGRKLIEAGEFDPEKVKSEMLAILSKGQRIKSD
YVEIVDEETLYPIENLEDTTNGKVILAIAAFVGKARLIDNEIVNLKMK
>Mature_288_residues
MRVIESPKEMQKIAIDIEREEKSHGFVPTMGYLHEGHLSLVRQARMDNVVVTVSIFVNPTQFGPNEDYDRYPRDEERDLS
LLRDLDVDYVFIPKVEDMYPDNYSTYVIVEDLTDVLCGARRPGHFKGVATIVAKLFNIVRPTKAYFGQKDAQQFRVLKRM
ARDLNFPVELVEMPIVREKDGLAMSSRNVYLSPEERQEALLIHQALLAGRKLIEAGEFDPEKVKSEMLAILSKGQRIKSD
YVEIVDEETLYPIENLEDTTNGKVILAIAAFVGKARLIDNEIVNLKMK

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=292, Percent_Identity=41.7808219178082, Blast_Score=214, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=288, Percent_Identity=39.9305555555556, Blast_Score=192, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32991; Mature: 32991

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIESPKEMQKIAIDIEREEKSHGFVPTMGYLHEGHLSLVRQARMDNVVVTVSIFVNPT
CCCCCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECC
QFGPNEDYDRYPRDEERDLSLLRDLDVDYVFIPKVEDMYPDNYSTYVIVEDLTDVLCGAR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHCCCCCCEEEEEHHHHHHHHHCCC
RPGHFKGVATIVAKLFNIVRPTKAYFGQKDAQQFRVLKRMARDLNFPVELVEMPIVREKD
CCCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCEECCC
GLAMSSRNVYLSPEERQEALLIHQALLAGRKLIEAGEFDPEKVKSEMLAILSKGQRIKSD
CCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
YVEIVDEETLYPIENLEDTTNGKVILAIAAFVGKARLIDNEIVNLKMK
HHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEEC
>Mature Secondary Structure
MRVIESPKEMQKIAIDIEREEKSHGFVPTMGYLHEGHLSLVRQARMDNVVVTVSIFVNPT
CCCCCCHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEECC
QFGPNEDYDRYPRDEERDLSLLRDLDVDYVFIPKVEDMYPDNYSTYVIVEDLTDVLCGAR
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEECCHHHCCCCCCEEEEEHHHHHHHHHCCC
RPGHFKGVATIVAKLFNIVRPTKAYFGQKDAQQFRVLKRMARDLNFPVELVEMPIVREKD
CCCCHHHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCCEECCC
GLAMSSRNVYLSPEERQEALLIHQALLAGRKLIEAGEFDPEKVKSEMLAILSKGQRIKSD
CCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
YVEIVDEETLYPIENLEDTTNGKVILAIAAFVGKARLIDNEIVNLKMK
HHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA