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The map label for this gene is lolC [H]

Identifier: 239617953

GI number: 239617953

Start: 1695139

End: 1696242

Strand: Direct

Name: lolC [H]

Synonym: Kole_1581

Alternate gene names: 239617953

Gene position: 1695139-1696242 (Clockwise)

Preceding gene: 239617952

Following gene: 239617954

Centisome position: 73.63

GC content: 41.39

Gene sequence:

>1104_bases
ATGAGAAATCTTTCTGTTAGTTTAGAACTTGCGAGAGCTTTCAGCTCGAGAAACAGAAAACACTTTGTTTTGCCGTTTTT
AGCCATAGTGATAGGGCTTATCGGGTTAATCGTGGTGTTGTCGGTTATCAACGGTTTCGATTCACTGTTGATCGAGTCAT
TAACCTCATTTTTTCCTCATCTTCTCGTTGATTCACCTGATTACGTTCCTTCAGGAATAAATGAGCTTCTTACCTATTTT
CCTCTTTCAATACATGAAGGTGTGGTATCGATGGGGACCAACTTTTCGGGAAGCTTTGTTTATACCACAAATGAGGATGG
ATTGAGATATATCGACCGGTTTCTTCAGGATGGCAGAATGCCACTTGCAGAGAGTGAAATAGTTCTTGGCAAAGAGATAA
TGGAAAAGCTTGCGCTGACGATTGGAGATATCATTCTGTTGTACTCTTATAAGGGGAGAGAGCCTGTTTCGAAGCAGTAT
ACAGTGGTTGGGACCCTAAACACGGGAATTTATCAGTTCGATTCTTCTGTGTGTGTGATACGAGGAGATCTGTTTGATTT
TACTGCTGTTTATTTACTTGATCCGATGAAAGCCGGTGAGTTCAAGAGAAGGATCGAGAAGGATACATCTTTCGTTGTTT
ATTCCTGGCAGGAACTCAATCAGAGTTTTTATAAAGCGGTGAAGATGGATGAATTTTTTGCGATGTTGATCACTGTTTTT
GTCGTTCTCCTATCAGGATTTGGTGTTTCCAATTCAATACTCTATTCGGTGCTTACCAGAAAGAAGGAAATAGCGGTACT
GAGCTCGCTGGGTTTATCTTCGAGAAGCATCTCAGCGATTTTTGGGTTTCAGGTAGCATATATAGCAACCTTTGGCTCAG
CGATTGGAGTTAGTGCTGGCGTGATGATCTCTTATCTCATCTCGAAGATACAAATACCGTTACCTTCGGATATTTTTTAC
ACCACATCTTTACCGGTAAAGATAGAACCCTTGCATGTGTTGATCGCTGTGATTTTTGAGTTTTCTCTGGCTATCGTATT
TTCGATGATTCCTGCAAGGATGGCCGGGAAGATCGATCCCATGGAGGTACTGAGATATGAGTGA

Upstream 100 bases:

>100_bases
AAGGCCTGAAGCAGTATTTTGAGGTTGTTCGATGGTTAGCTTCAGGGCGTTTTTATAAGAGTGGTTACGATGCGATTGTT
ATTTTGGGGGTAAGCGGTAA

Downstream 100 bases:

>100_bases
GTTACTGCTCAAGATAGTAAACGTGGGTCATAATTACGGGAAGGTTCAGGTTCTGGAGAACTTGAATCTGACCATACAGC
ACCATGGTATTGTGGGTATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRNLSVSLELARAFSSRNRKHFVLPFLAIVIGLIGLIVVLSVINGFDSLLIESLTSFFPHLLVDSPDYVPSGINELLTYF
PLSIHEGVVSMGTNFSGSFVYTTNEDGLRYIDRFLQDGRMPLAESEIVLGKEIMEKLALTIGDIILLYSYKGREPVSKQY
TVVGTLNTGIYQFDSSVCVIRGDLFDFTAVYLLDPMKAGEFKRRIEKDTSFVVYSWQELNQSFYKAVKMDEFFAMLITVF
VVLLSGFGVSNSILYSVLTRKKEIAVLSSLGLSSRSISAIFGFQVAYIATFGSAIGVSAGVMISYLISKIQIPLPSDIFY
TTSLPVKIEPLHVLIAVIFEFSLAIVFSMIPARMAGKIDPMEVLRYE

Sequences:

>Translated_367_residues
MRNLSVSLELARAFSSRNRKHFVLPFLAIVIGLIGLIVVLSVINGFDSLLIESLTSFFPHLLVDSPDYVPSGINELLTYF
PLSIHEGVVSMGTNFSGSFVYTTNEDGLRYIDRFLQDGRMPLAESEIVLGKEIMEKLALTIGDIILLYSYKGREPVSKQY
TVVGTLNTGIYQFDSSVCVIRGDLFDFTAVYLLDPMKAGEFKRRIEKDTSFVVYSWQELNQSFYKAVKMDEFFAMLITVF
VVLLSGFGVSNSILYSVLTRKKEIAVLSSLGLSSRSISAIFGFQVAYIATFGSAIGVSAGVMISYLISKIQIPLPSDIFY
TTSLPVKIEPLHVLIAVIFEFSLAIVFSMIPARMAGKIDPMEVLRYE
>Mature_367_residues
MRNLSVSLELARAFSSRNRKHFVLPFLAIVIGLIGLIVVLSVINGFDSLLIESLTSFFPHLLVDSPDYVPSGINELLTYF
PLSIHEGVVSMGTNFSGSFVYTTNEDGLRYIDRFLQDGRMPLAESEIVLGKEIMEKLALTIGDIILLYSYKGREPVSKQY
TVVGTLNTGIYQFDSSVCVIRGDLFDFTAVYLLDPMKAGEFKRRIEKDTSFVVYSWQELNQSFYKAVKMDEFFAMLITVF
VVLLSGFGVSNSILYSVLTRKKEIAVLSSLGLSSRSISAIFGFQVAYIATFGSAIGVSAGVMISYLISKIQIPLPSDIFY
TTSLPVKIEPLHVLIAVIFEFSLAIVFSMIPARMAGKIDPMEVLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=398, Percent_Identity=21.608040201005, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787362, Length=385, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787105, Length=165, Percent_Identity=24.8484848484848, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 40842; Mature: 40842

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLSVSLELARAFSSRNRKHFVLPFLAIVIGLIGLIVVLSVINGFDSLLIESLTSFFPH
CCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDSPDYVPSGINELLTYFPLSIHEGVVSMGTNFSGSFVYTTNEDGLRYIDRFLQDGRM
HHCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCC
PLAESEIVLGKEIMEKLALTIGDIILLYSYKGREPVSKQYTVVGTLNTGIYQFDSSVCVI
CCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCEEEECCCEEEE
RGDLFDFTAVYLLDPMKAGEFKRRIEKDTSFVVYSWQELNQSFYKAVKMDEFFAMLITVF
ECCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VVLLSGFGVSNSILYSVLTRKKEIAVLSSLGLSSRSISAIFGFQVAYIATFGSAIGVSAG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VMISYLISKIQIPLPSDIFYTTSLPVKIEPLHVLIAVIFEFSLAIVFSMIPARMAGKIDP
HHHHHHHHHHCCCCCCCEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
MEVLRYE
HHHHCCC
>Mature Secondary Structure
MRNLSVSLELARAFSSRNRKHFVLPFLAIVIGLIGLIVVLSVINGFDSLLIESLTSFFPH
CCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLVDSPDYVPSGINELLTYFPLSIHEGVVSMGTNFSGSFVYTTNEDGLRYIDRFLQDGRM
HHCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCC
PLAESEIVLGKEIMEKLALTIGDIILLYSYKGREPVSKQYTVVGTLNTGIYQFDSSVCVI
CCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCEEEEEEECCCEEEECCCEEEE
RGDLFDFTAVYLLDPMKAGEFKRRIEKDTSFVVYSWQELNQSFYKAVKMDEFFAMLITVF
ECCHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
VVLLSGFGVSNSILYSVLTRKKEIAVLSSLGLSSRSISAIFGFQVAYIATFGSAIGVSAG
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VMISYLISKIQIPLPSDIFYTTSLPVKIEPLHVLIAVIFEFSLAIVFSMIPARMAGKIDP
HHHHHHHHHHCCCCCCCEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
MEVLRYE
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]