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The map label for this gene is argS [H]

Identifier: 239617808

GI number: 239617808

Start: 1529314

End: 1530942

Strand: Direct

Name: argS [H]

Synonym: Kole_1434

Alternate gene names: 239617808

Gene position: 1529314-1530942 (Clockwise)

Preceding gene: 239617799

Following gene: 239617809

Centisome position: 66.43

GC content: 41.74

Gene sequence:

>1629_bases
GTGATAAAAGAACTTCTTAAGAACGATATAAAGCGAGTTGTCTCCGATCTTGGAATTGATGAAGTACCAGATTTCAAGGT
CGAAATACCGCCGGAGGAATTTGGAGATTATTCTACGAATGTTGCTTTTCTTCTGACAAAAAAACTCAGGAAAAGCCCGA
AGATGATCGCCGAGGAACTTTCTGGACGTTTTTCAGAATTAGAGTATGTCTTGAAAGTCACTGTTGCCGGTCCGGGATTT
ATAAACTTTGTTTTGAACGATTCGATATACAGAAAGAGCCTTTTTCATATTGTAGATAATCCTCGATTCTGGGAAAAAGA
AGGAGATACGCTTATTCAATTTGAATTTGGCAGTGCTAATCCCACGGGTCCGTACACCATTGGCCACGGAAGGCAGTTGA
TATTCGGTGATGTGCTTTGCAATGTTTTTCAGGCGAGAGGTTATCGCGTACACCGTGAGATGTATATAAATGATGCTGGA
CGGCAGATAAAGCTTCTGGGAAGATCTTTGTGGGTTAGATATAACGAGCTTTTTGGGAAGGAATACGAGCTTCCAGAGGA
TGGTTATCGCGGTGAATACCTGATCGATCTTGCCGAAGAATTGAAAATCAGTTATGGTGATAGGTTTGTAGATCGTTGGG
ACTCTGAGATCGAGGAGTTCTTTAAGAGTTATGCTGTTGGGAAGATAATGGAAGGAATGAAAGAATCCCTTGAACGCCTT
GGGATGTCCTTTGATAATTATTTCAGTGAGAAGTCGCTCGTAGATGATGGAAGTGTTGAAGAGATACTCCGAAAGTTCGA
TGAAATGGGTTTGACATATAGAAAGGATGGAGCTCTCTGGTTCGCCGTTTCAAAGTTTGTCGATGATGACGATAAGGTTC
TTGTACGTTCTGATGGAACATACACCTATTTTCTGACTGATATAGCCTATCACTACAACAAGTACAAAAGAGGTTATAGA
AGGGCTTACGACATATGGGGCGCTGATCACATGGGACATATTCCACGAATGAGAGCAGCTATGAAAGCGTTGGGAATTGC
CGATGATTTCCTTTATTTTATAATTCACCAATACGTCAATATAAAACGCGGCGGAGAAGTGATTAAGATGTCAACAAGGA
AAGGGCAATTCTCCACTCTCGATGAGCTCGTCGAGTCCGTTGGTAAGGATGCCACGAGATACTTTTTCGCTATGTTTGAC
CCTGATACCCACATGCTTTTTGATATAGATCTTGCAAAGAAGAAAAACAACGAAAATCCTGTATTTTACGTTCAATATGC
CCACGCCAGGATAGCAAGTATCTTTCGAACGGCTTCACAACGCGGGATGAAATTAGATACCAGGATTCCTGAAGTTCTTA
TGAATGAAGAAGAAAAGCGTTTAATAAAGCAACTCGGGAACTTCCCTGAGATACTGGATCAGATTACTGAGGATTATAAA
ACAAACCGGCTCACGAATTACCTTGAAAGCCTTGCGGGAGCTTTTCATGCTTTTTACAATAAACACGTTGTTGTGGATGC
GGATTCGCCGGAGCTAAGTATGTTCAGGCTTACACTTTGTAAAGCTGTTAAGAATGTTCTTAGTGATGGGCTGAGCCTTA
TCGGGGTTTCGGCGCCTGAAAGTATGTAG

Upstream 100 bases:

>100_bases
TGTAAACTTAGATTAAATTATATTGTCGCAATACAATGTTATGCTTCAGTATGCAAGAGTATGCGAGGTTATGCGAGTAT
ATTCATATGGAGGTGTGATC

Downstream 100 bases:

>100_bases
GTGGCTTGTATGAAGCAATTTACAGTTGAGAAGCTGATTTCTGACGGATACAGTTTTGCCAGAGATGAAAATGGAAAGGT
TGTGCTGTTAACAGAGGGGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MIKELLKNDIKRVVSDLGIDEVPDFKVEIPPEEFGDYSTNVAFLLTKKLRKSPKMIAEELSGRFSELEYVLKVTVAGPGF
INFVLNDSIYRKSLFHIVDNPRFWEKEGDTLIQFEFGSANPTGPYTIGHGRQLIFGDVLCNVFQARGYRVHREMYINDAG
RQIKLLGRSLWVRYNELFGKEYELPEDGYRGEYLIDLAEELKISYGDRFVDRWDSEIEEFFKSYAVGKIMEGMKESLERL
GMSFDNYFSEKSLVDDGSVEEILRKFDEMGLTYRKDGALWFAVSKFVDDDDKVLVRSDGTYTYFLTDIAYHYNKYKRGYR
RAYDIWGADHMGHIPRMRAAMKALGIADDFLYFIIHQYVNIKRGGEVIKMSTRKGQFSTLDELVESVGKDATRYFFAMFD
PDTHMLFDIDLAKKKNNENPVFYVQYAHARIASIFRTASQRGMKLDTRIPEVLMNEEEKRLIKQLGNFPEILDQITEDYK
TNRLTNYLESLAGAFHAFYNKHVVVDADSPELSMFRLTLCKAVKNVLSDGLSLIGVSAPESM

Sequences:

>Translated_542_residues
MIKELLKNDIKRVVSDLGIDEVPDFKVEIPPEEFGDYSTNVAFLLTKKLRKSPKMIAEELSGRFSELEYVLKVTVAGPGF
INFVLNDSIYRKSLFHIVDNPRFWEKEGDTLIQFEFGSANPTGPYTIGHGRQLIFGDVLCNVFQARGYRVHREMYINDAG
RQIKLLGRSLWVRYNELFGKEYELPEDGYRGEYLIDLAEELKISYGDRFVDRWDSEIEEFFKSYAVGKIMEGMKESLERL
GMSFDNYFSEKSLVDDGSVEEILRKFDEMGLTYRKDGALWFAVSKFVDDDDKVLVRSDGTYTYFLTDIAYHYNKYKRGYR
RAYDIWGADHMGHIPRMRAAMKALGIADDFLYFIIHQYVNIKRGGEVIKMSTRKGQFSTLDELVESVGKDATRYFFAMFD
PDTHMLFDIDLAKKKNNENPVFYVQYAHARIASIFRTASQRGMKLDTRIPEVLMNEEEKRLIKQLGNFPEILDQITEDYK
TNRLTNYLESLAGAFHAFYNKHVVVDADSPELSMFRLTLCKAVKNVLSDGLSLIGVSAPESM
>Mature_542_residues
MIKELLKNDIKRVVSDLGIDEVPDFKVEIPPEEFGDYSTNVAFLLTKKLRKSPKMIAEELSGRFSELEYVLKVTVAGPGF
INFVLNDSIYRKSLFHIVDNPRFWEKEGDTLIQFEFGSANPTGPYTIGHGRQLIFGDVLCNVFQARGYRVHREMYINDAG
RQIKLLGRSLWVRYNELFGKEYELPEDGYRGEYLIDLAEELKISYGDRFVDRWDSEIEEFFKSYAVGKIMEGMKESLERL
GMSFDNYFSEKSLVDDGSVEEILRKFDEMGLTYRKDGALWFAVSKFVDDDDKVLVRSDGTYTYFLTDIAYHYNKYKRGYR
RAYDIWGADHMGHIPRMRAAMKALGIADDFLYFIIHQYVNIKRGGEVIKMSTRKGQFSTLDELVESVGKDATRYFFAMFD
PDTHMLFDIDLAKKKNNENPVFYVQYAHARIASIFRTASQRGMKLDTRIPEVLMNEEEKRLIKQLGNFPEILDQITEDYK
TNRLTNYLESLAGAFHAFYNKHVVVDADSPELSMFRLTLCKAVKNVLSDGLSLIGVSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=618, Percent_Identity=24.9190938511327, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI197100773, Length=563, Percent_Identity=24.1563055062167, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1788184, Length=552, Percent_Identity=24.4565217391304, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71985061, Length=183, Percent_Identity=30.0546448087432, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985068, Length=183, Percent_Identity=30.0546448087432, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320548, Length=559, Percent_Identity=26.2969588550984, Blast_Score=114, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321883, Length=550, Percent_Identity=22.9090909090909, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62701; Mature: 62701

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKELLKNDIKRVVSDLGIDEVPDFKVEIPPEEFGDYSTNVAFLLTKKLRKSPKMIAEEL
CHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
SGRFSELEYVLKVTVAGPGFINFVLNDSIYRKSLFHIVDNPRFWEKEGDTLIQFEFGSAN
CCHHHHHEEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
PTGPYTIGHGRQLIFGDVLCNVFQARGYRVHREMYINDAGRQIKLLGRSLWVRYNELFGK
CCCCEEECCCCHHHHHHHHHHHHHHCCEEEEHHHEECCCCCCHHHHHHHHHHHHHHHCCC
EYELPEDGYRGEYLIDLAEELKISYGDRFVDRWDSEIEEFFKSYAVGKIMEGMKESLERL
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMSFDNYFSEKSLVDDGSVEEILRKFDEMGLTYRKDGALWFAVSKFVDDDDKVLVRSDGT
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCEEEECCCC
YTYFLTDIAYHYNKYKRGYRRAYDIWGADHMGHIPRMRAAMKALGIADDFLYFIIHQYVN
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
IKRGGEVIKMSTRKGQFSTLDELVESVGKDATRYFFAMFDPDTHMLFDIDLAKKKNNENP
HCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEEEEEECCCCEEEEEEEHHHCCCCCCC
VFYVQYAHARIASIFRTASQRGMKLDTRIPEVLMNEEEKRLIKQLGNFPEILDQITEDYK
EEEEEEHHHHHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
TNRLTNYLESLAGAFHAFYNKHVVVDADSPELSMFRLTLCKAVKNVLSDGLSLIGVSAPE
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
SM
CC
>Mature Secondary Structure
MIKELLKNDIKRVVSDLGIDEVPDFKVEIPPEEFGDYSTNVAFLLTKKLRKSPKMIAEEL
CHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHHHCCCCCCHHHHHHHHHHCCHHHHHHHH
SGRFSELEYVLKVTVAGPGFINFVLNDSIYRKSLFHIVDNPRFWEKEGDTLIQFEFGSAN
CCHHHHHEEEEEEEECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
PTGPYTIGHGRQLIFGDVLCNVFQARGYRVHREMYINDAGRQIKLLGRSLWVRYNELFGK
CCCCEEECCCCHHHHHHHHHHHHHHCCEEEEHHHEECCCCCCHHHHHHHHHHHHHHHCCC
EYELPEDGYRGEYLIDLAEELKISYGDRFVDRWDSEIEEFFKSYAVGKIMEGMKESLERL
CCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMSFDNYFSEKSLVDDGSVEEILRKFDEMGLTYRKDGALWFAVSKFVDDDDKVLVRSDGT
CCCHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECCCEEEEEEHHHCCCCCCEEEECCCC
YTYFLTDIAYHYNKYKRGYRRAYDIWGADHMGHIPRMRAAMKALGIADDFLYFIIHQYVN
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
IKRGGEVIKMSTRKGQFSTLDELVESVGKDATRYFFAMFDPDTHMLFDIDLAKKKNNENP
HCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHEEEEEEECCCCEEEEEEEHHHCCCCCCC
VFYVQYAHARIASIFRTASQRGMKLDTRIPEVLMNEEEKRLIKQLGNFPEILDQITEDYK
EEEEEEHHHHHHHHHHHHHHCCCCCHHCCHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHH
TNRLTNYLESLAGAFHAFYNKHVVVDADSPELSMFRLTLCKAVKNVLSDGLSLIGVSAPE
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCC
SM
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]