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The map label for this gene is hrcA [H]

Identifier: 239617759

GI number: 239617759

Start: 1471941

End: 1472987

Strand: Direct

Name: hrcA [H]

Synonym: Kole_1384

Alternate gene names: 239617759

Gene position: 1471941-1472987 (Clockwise)

Preceding gene: 239617751

Following gene: 239617760

Centisome position: 63.94

GC content: 41.55

Gene sequence:

>1047_bases
ATGCCGGCGAGAAGAAAAACTGATGGTCCAAAACTCAACGATAGACAGGTAAGGGTCTTATATTGTATAACAAGGGAATA
TATAACTCACGGGAAACCTGTAAGTTCAAAGCAGGTATTGGAACGTTCTGACCTGATGTATAGTTCGGCAACTATTAGAA
ATGATATGAGAAAGCTGGAGTTCCTCGGTTATATCTATCAACCTCATACATCAGCGGGGCGGATCCCCACTGACAAGGGG
CTCCGTTTCTATCTCGAATCTATAAAGGAGTTGAATGATGAGCTCAAAGAAAGCTCCGCGGCGATATCGCTACGGCAGGT
TTCGGTAATAGGTGATATAGAACATCTCTTGATGGGGATGGCCAGAATCATAGCAAAGGTTTCTTCGGCTTTTGTTATGG
TAGAGCGTCCTGACATAGATAAGCTTGTAGTCAAGCATGTAGCTATATCACCGGTAACGGAAGGCTATTTGAATGTGACA
GTCGTTACAGATCTTGGAGTTACAGTCAATTCAACGGTTTTTGCCGGTTATGAATATCACAATTATCTGGACCTTCAAAA
ACGCGTAAACAGCGTCGTAGCGGGAAAAACTATCGGTGAGATCAGAGAAGGGCTAAGGAATTTTAAGCTTGTTCAGGAAC
AGTGGTATAGCAAAGAAATCGAAGAGCTGTTCTATTTTCTCGGAGGTGTTTTTGAAAACGATGGTGGTGAAAGGTATTAT
AAATATGGTCTGGAATATCTCGTTACTAATAAGAATCTCGGCTGGCAGGATATCTCCGGGCTGGTAAAGTACATTGAAAA
TCCCAGAAAGCTTGAGATACTTATGAGCAAATTTTCGGAAGTATCGACAGAGAAGGTTCTTATTGGTAATGAGATAGAAA
TTCCAGAATTGAAGAACTTTGCTCTGTTTGTTGCACCTTATAAACGATTCAGTGAGAAACTGGGGATGATAGTGATTATG
GCGTCGAAAATAAACCTTTATGAAACAACGTACGCGTATTTGCGATTCGCTTCGAATAGGCTTTCGGAAGCGTTTAGCAA
GAGGTAG

Upstream 100 bases:

>100_bases
CCCCTTTCGCTGAAACTATTGTATCATCGCAATTTCGACTTGACAACAGGTATACTACATGCTAATATTAAATTAGCAGT
CTCCAGGGAGGAGTGCTAAT

Downstream 100 bases:

>100_bases
TGAGTCAGGAGGTGATAATATGTCAGAAGAAGCCAGAAAGAATTTGAAAAAGAGTGTTGAGAATAAAGGAGAGTTTGAAA
AAAAGATAAAGAAGGAAGCC

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPARRKTDGPKLNDRQVRVLYCITREYITHGKPVSSKQVLERSDLMYSSATIRNDMRKLEFLGYIYQPHTSAGRIPTDKG
LRFYLESIKELNDELKESSAAISLRQVSVIGDIEHLLMGMARIIAKVSSAFVMVERPDIDKLVVKHVAISPVTEGYLNVT
VVTDLGVTVNSTVFAGYEYHNYLDLQKRVNSVVAGKTIGEIREGLRNFKLVQEQWYSKEIEELFYFLGGVFENDGGERYY
KYGLEYLVTNKNLGWQDISGLVKYIENPRKLEILMSKFSEVSTEKVLIGNEIEIPELKNFALFVAPYKRFSEKLGMIVIM
ASKINLYETTYAYLRFASNRLSEAFSKR

Sequences:

>Translated_348_residues
MPARRKTDGPKLNDRQVRVLYCITREYITHGKPVSSKQVLERSDLMYSSATIRNDMRKLEFLGYIYQPHTSAGRIPTDKG
LRFYLESIKELNDELKESSAAISLRQVSVIGDIEHLLMGMARIIAKVSSAFVMVERPDIDKLVVKHVAISPVTEGYLNVT
VVTDLGVTVNSTVFAGYEYHNYLDLQKRVNSVVAGKTIGEIREGLRNFKLVQEQWYSKEIEELFYFLGGVFENDGGERYY
KYGLEYLVTNKNLGWQDISGLVKYIENPRKLEILMSKFSEVSTEKVLIGNEIEIPELKNFALFVAPYKRFSEKLGMIVIM
ASKINLYETTYAYLRFASNRLSEAFSKR
>Mature_347_residues
PARRKTDGPKLNDRQVRVLYCITREYITHGKPVSSKQVLERSDLMYSSATIRNDMRKLEFLGYIYQPHTSAGRIPTDKGL
RFYLESIKELNDELKESSAAISLRQVSVIGDIEHLLMGMARIIAKVSSAFVMVERPDIDKLVVKHVAISPVTEGYLNVTV
VTDLGVTVNSTVFAGYEYHNYLDLQKRVNSVVAGKTIGEIREGLRNFKLVQEQWYSKEIEELFYFLGGVFENDGGERYYK
YGLEYLVTNKNLGWQDISGLVKYIENPRKLEILMSKFSEVSTEKVLIGNEIEIPELKNFALFVAPYKRFSEKLGMIVIMA
SKINLYETTYAYLRFASNRLSEAFSKR

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR023120
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39917; Mature: 39785

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPARRKTDGPKLNDRQVRVLYCITREYITHGKPVSSKQVLERSDLMYSSATIRNDMRKLE
CCCCCCCCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLGYIYQPHTSAGRIPTDKGLRFYLESIKELNDELKESSAAISLRQVSVIGDIEHLLMGM
HHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIIAKVSSAFVMVERPDIDKLVVKHVAISPVTEGYLNVTVVTDLGVTVNSTVFAGYEYH
HHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCEECCEEEECCHHH
NYLDLQKRVNSVVAGKTIGEIREGLRNFKLVQEQWYSKEIEELFYFLGGVFENDGGERYY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHH
KYGLEYLVTNKNLGWQDISGLVKYIENPRKLEILMSKFSEVSTEKVLIGNEIEIPELKNF
HHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
ALFVAPYKRFSEKLGMIVIMASKINLYETTYAYLRFASNRLSEAFSKR
EEEEEHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PARRKTDGPKLNDRQVRVLYCITREYITHGKPVSSKQVLERSDLMYSSATIRNDMRKLE
CCCCCCCCCCCCCCCEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FLGYIYQPHTSAGRIPTDKGLRFYLESIKELNDELKESSAAISLRQVSVIGDIEHLLMGM
HHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARIIAKVSSAFVMVERPDIDKLVVKHVAISPVTEGYLNVTVVTDLGVTVNSTVFAGYEYH
HHHHHHHHHHEEEEECCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCEECCEEEECCHHH
NYLDLQKRVNSVVAGKTIGEIREGLRNFKLVQEQWYSKEIEELFYFLGGVFENDGGERYY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCHHH
KYGLEYLVTNKNLGWQDISGLVKYIENPRKLEILMSKFSEVSTEKVLIGNEIEIPELKNF
HHCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCC
ALFVAPYKRFSEKLGMIVIMASKINLYETTYAYLRFASNRLSEAFSKR
EEEEEHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]