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The map label for this gene is dinB [H]

Identifier: 239617640

GI number: 239617640

Start: 1338442

End: 1339716

Strand: Reverse

Name: dinB [H]

Synonym: Kole_1261

Alternate gene names: 239617640

Gene position: 1339716-1338442 (Counterclockwise)

Preceding gene: 239617642

Following gene: 239617639

Centisome position: 58.19

GC content: 38.43

Gene sequence:

>1275_bases
GTGTCTATAAATTCTCAGTTAGGGCTTCGAGGAATATCCACATTCTCGAATATAAAGAATTTGACAAACAGTGGTATTAC
CACGAAAGTCAGTACTGGTAAGTCACGAAAGTCAATTCCCTACATCGCACACGTCGATATGGACGCTTTTTTTGCCAGTG
TGGAACAAGCCTCCAATCCTTATCTTAAGGGCAAACCAATCATTGTGACTGGAAAAGATACAAGGCATTCTGTGGTCGTT
TCGGCAAGTTACGAAGCTAAAAAATACGGAGTTAAAGCGGGTATGCCTGCCTTTAAGGCCTTAGAAATATGTCCGAAAGC
TTTATTTGTGCCTGTTGATAGTGGCAAATACACATACGTATCCGAAGAAATTATGAAACGCCTTGAATTCATATCTCCAA
GATATTCTGTAGCGAGTATCGATGAAGCATTTATTGATTTATCCGTATATCATAGTTTGTCTGATTCTATAAATGCTTTG
AAGCTTTTTAGAACCTCTATCGAGAAAACCTTCGGGATTTCTTTTTCAATAGGTGTTGCAGTAAACCCTTTAATTGCCAA
AATCGCGAGTGATTTTAATAAGCCACGGGGATTTGTCGTGGTTAAAGAGGGATCAGAAAAGGCTTTTTTGCAGAATGTCG
ATATATCTCAGGTTCCGGGTATTGGACCACACACGCTGATGAAATTAGAAAACTTTGGTTTTAAAAAAGCCTCTGAATTA
TTAGAAGCAGATGAGTTTTTCCTTTACCACAATTTTGGAAATTCTTTCCTGGGGCTCGTTAAATCACTTACCGTTAAAAA
TTATCCAAAAGAATTGTTTTTTAAAAAAGAACCACCAAAATCTGTGGGGCATTCGATGACTCTCAATCATGATGTAAATT
CAATAGAACTTATCGAAAGGGTCGCAAGTTTTCTCGGCGCGAAAGCTGTTTACAGAATGAGAAAATACGGATACCAGGCA
AGAGGAACCAGTCTGTTTTTAAAATACAGCGATTTCAGCGTTGCCAGAATCACGAGAAGTCTTTCCTTTTATATTTCACG
CCCGGAACACTTGAACAATGTTCTTTACTGGTTGATAAGAGAAATATGGAACGGTGAAGCCGTAAGGGCAGTAGGGGTTT
CTCTTTACAAACTTAAGCCTGTAAATAAAAACGTATATCAAGAAAACTTATTTAAAAAAGAAAAAGACACGGTCGAAGTC
GTTCTCAATCTCCAGAATCATTTCGGAGAGTACTCAATTTTCCCTGCTTCCATTCTCGCCGTCGCTAGTATTTGA

Upstream 100 bases:

>100_bases
GAAAAAGGTTTTTTCTTTCCCATCTATTTCGTACTCAATGACAGAAAAATTCGAATAGAAAAGGTTGTATACGTCTGGAA
AGAACGTAGGGGGGATTATC

Downstream 100 bases:

>100_bases
GTTATTCTCCGATCAGACGCTGGGAACGGCTGTCGCCGTTGATGGTGGGAGTTACCTAACGGCAACTGACGCTGGGCGGA
GCATAGCTTCGGATGCTTGG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSINSQLGLRGISTFSNIKNLTNSGITTKVSTGKSRKSIPYIAHVDMDAFFASVEQASNPYLKGKPIIVTGKDTRHSVVV
SASYEAKKYGVKAGMPAFKALEICPKALFVPVDSGKYTYVSEEIMKRLEFISPRYSVASIDEAFIDLSVYHSLSDSINAL
KLFRTSIEKTFGISFSIGVAVNPLIAKIASDFNKPRGFVVVKEGSEKAFLQNVDISQVPGIGPHTLMKLENFGFKKASEL
LEADEFFLYHNFGNSFLGLVKSLTVKNYPKELFFKKEPPKSVGHSMTLNHDVNSIELIERVASFLGAKAVYRMRKYGYQA
RGTSLFLKYSDFSVARITRSLSFYISRPEHLNNVLYWLIREIWNGEAVRAVGVSLYKLKPVNKNVYQENLFKKEKDTVEV
VLNLQNHFGEYSIFPASILAVASI

Sequences:

>Translated_424_residues
MSINSQLGLRGISTFSNIKNLTNSGITTKVSTGKSRKSIPYIAHVDMDAFFASVEQASNPYLKGKPIIVTGKDTRHSVVV
SASYEAKKYGVKAGMPAFKALEICPKALFVPVDSGKYTYVSEEIMKRLEFISPRYSVASIDEAFIDLSVYHSLSDSINAL
KLFRTSIEKTFGISFSIGVAVNPLIAKIASDFNKPRGFVVVKEGSEKAFLQNVDISQVPGIGPHTLMKLENFGFKKASEL
LEADEFFLYHNFGNSFLGLVKSLTVKNYPKELFFKKEPPKSVGHSMTLNHDVNSIELIERVASFLGAKAVYRMRKYGYQA
RGTSLFLKYSDFSVARITRSLSFYISRPEHLNNVLYWLIREIWNGEAVRAVGVSLYKLKPVNKNVYQENLFKKEKDTVEV
VLNLQNHFGEYSIFPASILAVASI
>Mature_423_residues
SINSQLGLRGISTFSNIKNLTNSGITTKVSTGKSRKSIPYIAHVDMDAFFASVEQASNPYLKGKPIIVTGKDTRHSVVVS
ASYEAKKYGVKAGMPAFKALEICPKALFVPVDSGKYTYVSEEIMKRLEFISPRYSVASIDEAFIDLSVYHSLSDSINALK
LFRTSIEKTFGISFSIGVAVNPLIAKIASDFNKPRGFVVVKEGSEKAFLQNVDISQVPGIGPHTLMKLENFGFKKASELL
EADEFFLYHNFGNSFLGLVKSLTVKNYPKELFFKKEPPKSVGHSMTLNHDVNSIELIERVASFLGAKAVYRMRKYGYQAR
GTSLFLKYSDFSVARITRSLSFYISRPEHLNNVLYWLIREIWNGEAVRAVGVSLYKLKPVNKNVYQENLFKKEKDTVEVV
LNLQNHFGEYSIFPASILAVASI

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI154350220, Length=328, Percent_Identity=27.7439024390244, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI7705344, Length=117, Percent_Identity=38.4615384615385, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI84043967, Length=268, Percent_Identity=25.7462686567164, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI7706681, Length=269, Percent_Identity=25.2788104089219, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI5729982, Length=130, Percent_Identity=37.6923076923077, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786425, Length=348, Percent_Identity=30.4597701149425, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1787432, Length=304, Percent_Identity=26.9736842105263, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=228, Percent_Identity=29.8245614035088, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193205700, Length=106, Percent_Identity=37.7358490566038, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115534089, Length=123, Percent_Identity=38.2113821138211, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=28.5024154589372, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19923006, Length=424, Percent_Identity=22.877358490566, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 47407; Mature: 47276

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINSQLGLRGISTFSNIKNLTNSGITTKVSTGKSRKSIPYIAHVDMDAFFASVEQASNP
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHCCCC
YLKGKPIIVTGKDTRHSVVVSASYEAKKYGVKAGMPAFKALEICPKALFVPVDSGKYTYV
CCCCCCEEEECCCCCCEEEEEECCHHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEH
SEEIMKRLEFISPRYSVASIDEAFIDLSVYHSLSDSINALKLFRTSIEKTFGISFSIGVA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
VNPLIAKIASDFNKPRGFVVVKEGSEKAFLQNVDISQVPGIGPHTLMKLENFGFKKASEL
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCHHHCCCCCHHHHHHHHHCCCHHHHHH
LEADEFFLYHNFGNSFLGLVKSLTVKNYPKELFFKKEPPKSVGHSMTLNHDVNSIELIER
HHHHHEEEEECCCHHHHHHHHHHHHCCCCHHHCCCCCCCHHHCCCEEECCCCCHHHHHHH
VASFLGAKAVYRMRKYGYQARGTSLFLKYSDFSVARITRSLSFYISRPEHLNNVLYWLIR
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHEECCCHHHHHHHHHHHH
EIWNGEAVRAVGVSLYKLKPVNKNVYQENLFKKEKDTVEVVLNLQNHFGEYSIFPASILA
HHHCCCEEEECCEEEEEEECCCCHHHHHHHHHCCCCHHHHHEEHHHHCCCEEECHHHHHH
VASI
HHCC
>Mature Secondary Structure 
SINSQLGLRGISTFSNIKNLTNSGITTKVSTGKSRKSIPYIAHVDMDAFFASVEQASNP
CCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHCCCC
YLKGKPIIVTGKDTRHSVVVSASYEAKKYGVKAGMPAFKALEICPKALFVPVDSGKYTYV
CCCCCCEEEECCCCCCEEEEEECCHHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCEEEH
SEEIMKRLEFISPRYSVASIDEAFIDLSVYHSLSDSINALKLFRTSIEKTFGISFSIGVA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCH
VNPLIAKIASDFNKPRGFVVVKEGSEKAFLQNVDISQVPGIGPHTLMKLENFGFKKASEL
HHHHHHHHHHHCCCCCCEEEEECCCCCHHHCCCCHHHCCCCCHHHHHHHHHCCCHHHHHH
LEADEFFLYHNFGNSFLGLVKSLTVKNYPKELFFKKEPPKSVGHSMTLNHDVNSIELIER
HHHHHEEEEECCCHHHHHHHHHHHHCCCCHHHCCCCCCCHHHCCCEEECCCCCHHHHHHH
VASFLGAKAVYRMRKYGYQARGTSLFLKYSDFSVARITRSLSFYISRPEHLNNVLYWLIR
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHEECCCHHHHHHHHHHHH
EIWNGEAVRAVGVSLYKLKPVNKNVYQENLFKKEKDTVEVVLNLQNHFGEYSIFPASILA
HHHCCCEEEECCEEEEEEECCCCHHHHHHHHHCCCCHHHHHEEHHHHCCCEEECHHHHHH
VASI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA