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The map label for this gene is nagD [H]

Identifier: 239617528

GI number: 239617528

Start: 1214487

End: 1215254

Strand: Direct

Name: nagD [H]

Synonym: Kole_1144

Alternate gene names: 239617528

Gene position: 1214487-1215254 (Clockwise)

Preceding gene: 239617523

Following gene: 239617529

Centisome position: 52.76

GC content: 40.76

Gene sequence:

>768_bases
GTGAAAAAACTGTTTGTGCTGGATATGGATGGGACATTCTACCTCGGAAATACGCTTTTTCCTGAAAGCCTCGAATTTGT
GGAAAGAATTACAAGTACGGGTGCTAAGCTTGTTTTTTTGACAAACAATTCTTCGGCTACTCCTGAAGAGTATCACGACA
AACTGGTGCGCCTCGGTGTTCCAGAAGGTTCTTTTTCGGTTTATACTTCAGGAGAAGCTACCATGCGTTTTCTCAAGGAT
AACTATCCAGGTTCTTCCGTTTACTTGCTTGCCACACCGTCAGTTGAAAAGATGTTCGTTGATTCGGGGATAATTTTAGA
TGAAAAAGATCCAGACGTTGTTGTTTTAACCTACGATAAAACCCTGACCTTTAAGAAGATTTCAAAATTTTGTGGTTTTG
TAAGAGATGGCATTTCATATATAGCATCACATCCGGATATAAATTGTCCAACGGAAAGAGGATTTATCCCGGATGTGGGA
AGTTTTATGGCTTTGATCAAAACATCTACCGGTAGAGAACCAGACCATATTGTAGGAAAGCCAAATCCAACTATTCTCGA
AATGCTTATAGAGGAATTTGATGTGAATAGAGCCGACGTCATAATGGTTGGTGACAGACTCATGACCGACATTGAGTGTG
GTTTGAGAGCCGAAGTTACAACAGCGTTGGTACTTACAGGGGAAACAACCAGAGAGATGGTACCAGACAATCCCCCTTTC
ATTGTAGCGGATAACCTGCTTGATCTTCTTAAAAAGTTAGGATATTGA

Upstream 100 bases:

>100_bases
TATAATATATCCTGGTTGTATTGTAGCATGCTACAATATTGGAGATTGGTTTCTACGTTATAACTTATTCAGACCAGATT
ATCAACATTGGAGGTGCACT

Downstream 100 bases:

>100_bases
GATAAATAACGCGGTTTTTAACACAACGACTGTTCTTAAATAAAATCTTGAAACAGTTCGATTTTTTAGCTCTTATATTG
TAAAATAAAAGTATGAAAGT

Product: HAD-superfamily hydrolase, subfamily IIA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MKKLFVLDMDGTFYLGNTLFPESLEFVERITSTGAKLVFLTNNSSATPEEYHDKLVRLGVPEGSFSVYTSGEATMRFLKD
NYPGSSVYLLATPSVEKMFVDSGIILDEKDPDVVVLTYDKTLTFKKISKFCGFVRDGISYIASHPDINCPTERGFIPDVG
SFMALIKTSTGREPDHIVGKPNPTILEMLIEEFDVNRADVIMVGDRLMTDIECGLRAEVTTALVLTGETTREMVPDNPPF
IVADNLLDLLKKLGY

Sequences:

>Translated_255_residues
MKKLFVLDMDGTFYLGNTLFPESLEFVERITSTGAKLVFLTNNSSATPEEYHDKLVRLGVPEGSFSVYTSGEATMRFLKD
NYPGSSVYLLATPSVEKMFVDSGIILDEKDPDVVVLTYDKTLTFKKISKFCGFVRDGISYIASHPDINCPTERGFIPDVG
SFMALIKTSTGREPDHIVGKPNPTILEMLIEEFDVNRADVIMVGDRLMTDIECGLRAEVTTALVLTGETTREMVPDNPPF
IVADNLLDLLKKLGY
>Mature_255_residues
MKKLFVLDMDGTFYLGNTLFPESLEFVERITSTGAKLVFLTNNSSATPEEYHDKLVRLGVPEGSFSVYTSGEATMRFLKD
NYPGSSVYLLATPSVEKMFVDSGIILDEKDPDVVVLTYDKTLTFKKISKFCGFVRDGISYIASHPDINCPTERGFIPDVG
SFMALIKTSTGREPDHIVGKPNPTILEMLIEEFDVNRADVIMVGDRLMTDIECGLRAEVTTALVLTGETTREMVPDNPPF
IVADNLLDLLKKLGY

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. NagD family [H]

Homologues:

Organism=Homo sapiens, GI10092677, Length=241, Percent_Identity=31.1203319502075, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI108796653, Length=294, Percent_Identity=28.2312925170068, Blast_Score=98, Evalue=9e-21,
Organism=Escherichia coli, GI1786890, Length=240, Percent_Identity=31.25, Blast_Score=116, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17558880, Length=253, Percent_Identity=25.6916996047431, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=263, Percent_Identity=25.4752851711027, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562458, Length=263, Percent_Identity=25.4752851711027, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI193210059, Length=256, Percent_Identity=28.125, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563050, Length=240, Percent_Identity=28.75, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71984613, Length=260, Percent_Identity=25, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6319965, Length=243, Percent_Identity=25.5144032921811, Blast_Score=92, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24666141, Length=244, Percent_Identity=26.6393442622951, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI18859765, Length=285, Percent_Identity=23.5087719298246, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920940, Length=252, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR006354
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 28316; Mature: 28316

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFVLDMDGTFYLGNTLFPESLEFVERITSTGAKLVFLTNNSSATPEEYHDKLVRLGV
CCEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEECC
PEGSFSVYTSGEATMRFLKDNYPGSSVYLLATPSVEKMFVDSGIILDEKDPDVVVLTYDK
CCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCHHHEEECCCEEEECCCCCEEEEEECC
TLTFKKISKFCGFVRDGISYIASHPDINCPTERGFIPDVGSFMALIKTSTGREPDHIVGK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
PNPTILEMLIEEFDVNRADVIMVGDRLMTDIECGLRAEVTTALVLTGETTREMVPDNPPF
CCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCEEEEEEEEEECCCHHHCCCCCCCE
IVADNLLDLLKKLGY
EEHHHHHHHHHHHCC
>Mature Secondary Structure
MKKLFVLDMDGTFYLGNTLFPESLEFVERITSTGAKLVFLTNNSSATPEEYHDKLVRLGV
CCEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHEEECC
PEGSFSVYTSGEATMRFLKDNYPGSSVYLLATPSVEKMFVDSGIILDEKDPDVVVLTYDK
CCCCEEEEECCHHHHHHHHCCCCCCEEEEEECCCHHHEEECCCEEEECCCCCEEEEEECC
TLTFKKISKFCGFVRDGISYIASHPDINCPTERGFIPDVGSFMALIKTSTGREPDHIVGK
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
PNPTILEMLIEEFDVNRADVIMVGDRLMTDIECGLRAEVTTALVLTGETTREMVPDNPPF
CCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCEEEEEEEEEECCCHHHCCCCCCCE
IVADNLLDLLKKLGY
EEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA