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The map label for this gene is htpX [H]

Identifier: 239617526

GI number: 239617526

Start: 1212805

End: 1213800

Strand: Reverse

Name: htpX [H]

Synonym: Kole_1142

Alternate gene names: 239617526

Gene position: 1213800-1212805 (Counterclockwise)

Preceding gene: 239617527

Following gene: 239617525

Centisome position: 52.73

GC content: 41.77

Gene sequence:

>996_bases
ATGGCTTTTACGGTCGATTTCTATACTGAAGAAAAGAAGAACGTTCGCAAGAGCGTTCTTCTGATTTTAATTTTCTTTCT
CATGATGCTTTTCTTTGGTCTTGTAATAGACTTTATGTTCAATATCTTCCCAATTTTTACCGCTATCTTTGGGAGCATTG
CAACAATACAGCTGCTTGTTTCCCTGATCTCCGGGAAGAATATCGTTTTGCACTCTGTAAATGCCCGACCTTTGAGGTTG
AATAATATCGAAGAAAAACAGCTAAAAAACATCGTGGAGGAACTTTCAATTGCCGCCGGTCTTCCCAAACCTCCCGACAT
CTATGTAATAGATGATGATTCCGTGATAAATGCCTTCGCTACCGGATTGAAAAAAGAAGACGGTGTAATCTGTGTCACTT
CAGGGTTGCTTAAAAACCTGAATAGAGAAGAGACATCCGGCGTTATCGCTCACGAATTGAGCCATATTATAAATAGAGAT
ATCCTTATAATGACTCTTATATCGGCTCTTTTAGGTGCTGTTGTTATAATCCAGATCTTCGCCGTTAGAGCCCTGTGGGG
ATACCTGCGTTTTGGCGGAAGAAGAGGAAGTCGAAAAGGTAAAGAAGGGAATTCTACCGCAGCCATCCTGGCATTCCTCG
CCGCGGTAGCAGGACTTGCGACTGTCTTTTCTTTTCTGGGACGCTTGTCGCTTTTTGCTGTTTCTAGAACACGAGAATTC
TTTGCAGATGCTCTAGGGGTAGAACTTACACGAAATCCAAACGGACTGGCGAATGCTTTGAGAAAGATAGCTAAAAACTC
TCGAAAGCTTAAAGTTGCAAATGTCGCAACGGCTCATCTCTTCATCGCAGATCCCTTGAAGAGAAAAGTTAATGAGAAAA
CTTCAAAACTCTCTTCGCTTTTCAGCACCCATCCGCCAATATATATGAGAATAGCTGTACTTGAAAACAGAGATCCCGAG
GAAGTTAAGAAAGAGATTTATGGGATTGAGAAGTGA

Upstream 100 bases:

>100_bases
TCGTTGCCGGTATGTATTCTTCCAAGTTCAAGCCGTTTCCTCTCTTTGAGATAACGGACGAGTCCGAAAGAGAAGTTCCG
AAGGTAGATCTTGGTTAACT

Downstream 100 bases:

>100_bases
AGTGCGGAGTTGCGCCCCGGAGGCTCGCAAGTCTGTGCGCTGCGAAGCAGCGGCAAGAATTCCTCCTGGGATTGACATGA
CCGGCTACGCCGGTGTTACG

Product: peptidase M48 Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MAFTVDFYTEEKKNVRKSVLLILIFFLMMLFFGLVIDFMFNIFPIFTAIFGSIATIQLLVSLISGKNIVLHSVNARPLRL
NNIEEKQLKNIVEELSIAAGLPKPPDIYVIDDDSVINAFATGLKKEDGVICVTSGLLKNLNREETSGVIAHELSHIINRD
ILIMTLISALLGAVVIIQIFAVRALWGYLRFGGRRGSRKGKEGNSTAAILAFLAAVAGLATVFSFLGRLSLFAVSRTREF
FADALGVELTRNPNGLANALRKIAKNSRKLKVANVATAHLFIADPLKRKVNEKTSKLSSLFSTHPPIYMRIAVLENRDPE
EVKKEIYGIEK

Sequences:

>Translated_331_residues
MAFTVDFYTEEKKNVRKSVLLILIFFLMMLFFGLVIDFMFNIFPIFTAIFGSIATIQLLVSLISGKNIVLHSVNARPLRL
NNIEEKQLKNIVEELSIAAGLPKPPDIYVIDDDSVINAFATGLKKEDGVICVTSGLLKNLNREETSGVIAHELSHIINRD
ILIMTLISALLGAVVIIQIFAVRALWGYLRFGGRRGSRKGKEGNSTAAILAFLAAVAGLATVFSFLGRLSLFAVSRTREF
FADALGVELTRNPNGLANALRKIAKNSRKLKVANVATAHLFIADPLKRKVNEKTSKLSSLFSTHPPIYMRIAVLENRDPE
EVKKEIYGIEK
>Mature_330_residues
AFTVDFYTEEKKNVRKSVLLILIFFLMMLFFGLVIDFMFNIFPIFTAIFGSIATIQLLVSLISGKNIVLHSVNARPLRLN
NIEEKQLKNIVEELSIAAGLPKPPDIYVIDDDSVINAFATGLKKEDGVICVTSGLLKNLNREETSGVIAHELSHIINRDI
LIMTLISALLGAVVIIQIFAVRALWGYLRFGGRRGSRKGKEGNSTAAILAFLAAVAGLATVFSFLGRLSLFAVSRTREFF
ADALGVELTRNPNGLANALRKIAKNSRKLKVANVATAHLFIADPLKRKVNEKTSKLSSLFSTHPPIYMRIAVLENRDPEE
VKKEIYGIEK

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=309, Percent_Identity=33.0097087378641, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 36648; Mature: 36517

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFTVDFYTEEKKNVRKSVLLILIFFLMMLFFGLVIDFMFNIFPIFTAIFGSIATIQLLV
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLISGKNIVLHSVNARPLRLNNIEEKQLKNIVEELSIAAGLPKPPDIYVIDDDSVINAFA
HHHCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
TGLKKEDGVICVTSGLLKNLNREETSGVIAHELSHIINRDILIMTLISALLGAVVIIQIF
HCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AVRALWGYLRFGGRRGSRKGKEGNSTAAILAFLAAVAGLATVFSFLGRLSLFAVSRTREF
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FADALGVELTRNPNGLANALRKIAKNSRKLKVANVATAHLFIADPLKRKVNEKTSKLSSL
HHHHHCCEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSTHPPIYMRIAVLENRDPEEVKKEIYGIEK
HHCCCCCEEEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
AFTVDFYTEEKKNVRKSVLLILIFFLMMLFFGLVIDFMFNIFPIFTAIFGSIATIQLLV
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLISGKNIVLHSVNARPLRLNNIEEKQLKNIVEELSIAAGLPKPPDIYVIDDDSVINAFA
HHHCCCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
TGLKKEDGVICVTSGLLKNLNREETSGVIAHELSHIINRDILIMTLISALLGAVVIIQIF
HCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AVRALWGYLRFGGRRGSRKGKEGNSTAAILAFLAAVAGLATVFSFLGRLSLFAVSRTREF
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FADALGVELTRNPNGLANALRKIAKNSRKLKVANVATAHLFIADPLKRKVNEKTSKLSSL
HHHHHCCEEECCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSTHPPIYMRIAVLENRDPEEVKKEIYGIEK
HHCCCCCEEEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA