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The map label for this gene is soxB [H]

Identifier: 239617400

GI number: 239617400

Start: 1070305

End: 1071447

Strand: Direct

Name: soxB [H]

Synonym: Kole_1011

Alternate gene names: 239617400

Gene position: 1070305-1071447 (Clockwise)

Preceding gene: 239617395

Following gene: 239617401

Centisome position: 46.49

GC content: 44.09

Gene sequence:

>1143_bases
ATGAATGAAAGGGCATCCGTTGTGATAATAGGTGGCGGAATAATTGGAACCGCCATAGCTTTTTACCTGTGCAAGAACGG
AATGAATGATGTAGTTGTTCTGGAGAAGAATTATCTTTCCTCAGGAGCTACGGGAAGATGCGGTGGGGGGATAAGGCAGC
AGTGGAGTGAAAGGATGAATATACGCCTTGCAATGAGGAGCGTGAAGCTTTTTGAAAACTTTGAAGAAGACGTTGGCATG
GATATAGAGTACTACCAGGGGGGATATTTGCTTCTCGCATACACAGATGAAGAGGTCGGTTTTTTCGAGAAAAATGTGAA
AATGCAGCAGGAAGAAGGGCTTGATGTTCGCATACTGACGAAACAAGAAATAGAACGTATGTTCCCATTTATGAATTCAG
AAGGTGTCAAATTGGCCACATACTGTCCCACAGACGGCCATGCCAACCCGCATTTAGCGACCTTTGCATATGCCAGAGCT
GCCGAAAGGATGGGAGCAAAGATTTACACTCACACAGAAGCCACAGGTATCGATGTTGCTAACGGTCAAATAATCGGTGT
TCAAACCAGTAAGAGTTATATTAAAACCTCCGTTGTCATAAATGCTGCAGGCGGTTATTCCAGAGAGGTCGGTTTGATGG
CAGGTGTGGAATTGCCGACAGAATCTTACCGCCACCAGATATTCGTTACGGAACCTCTCGAACATATACTCGATCCGTTG
GTTATAAGTTTCGAAAACAATTTTTATATCAGGCAGACAAAGTCCGGCAACTTCATCATGGGTCAGGGAGATAAGGATGA
GCCACCAAGCCACAATCACAATCCGAGCTGGCGCTTTTTAAAGGAAATGACTCAGAAGATGCCAAAATTCTTTCCTTTTC
TTGAGGACGTTAGGGTACTCAAGCATTGGGCTGGGTTGTACAACATGTCTCCAGATGCTCAACCCATAATAGATAAAGCG
GACAACGTACAGGATTTCTATTTTGCCGTGGGTTTTAGCGGGCACGGTTTCATGCTGGCACCTGCCGTTGGGGAAGCCCT
TGCGGAATGGATTGTTTACGGTAAACCGAAGAAAGTAGATATCTCAAATCTCAAAATAGATAGATTTGCAAAAGGTGTTT
CAAGAGAAAAAAATGTTGTATAA

Upstream 100 bases:

>100_bases
AGAAAAACAGGTATTCCTGTTGAGAAACTTGATCCCGGTACATTTAGACCTCCAACGGTTCCAACGACTTTTAGAGCCAT
CGCACGGGAGCGTGAAGAAG

Downstream 100 bases:

>100_bases
GGAGGTATGAATATGCCAGAGGCCACAGATTACATTATTCTTCCACCCTTTAAGAATGAAGGGTACATCAACGTTTCTGA
TCCAGAGATCCAGCGGAAGA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MNERASVVIIGGGIIGTAIAFYLCKNGMNDVVVLEKNYLSSGATGRCGGGIRQQWSERMNIRLAMRSVKLFENFEEDVGM
DIEYYQGGYLLLAYTDEEVGFFEKNVKMQQEEGLDVRILTKQEIERMFPFMNSEGVKLATYCPTDGHANPHLATFAYARA
AERMGAKIYTHTEATGIDVANGQIIGVQTSKSYIKTSVVINAAGGYSREVGLMAGVELPTESYRHQIFVTEPLEHILDPL
VISFENNFYIRQTKSGNFIMGQGDKDEPPSHNHNPSWRFLKEMTQKMPKFFPFLEDVRVLKHWAGLYNMSPDAQPIIDKA
DNVQDFYFAVGFSGHGFMLAPAVGEALAEWIVYGKPKKVDISNLKIDRFAKGVSREKNVV

Sequences:

>Translated_380_residues
MNERASVVIIGGGIIGTAIAFYLCKNGMNDVVVLEKNYLSSGATGRCGGGIRQQWSERMNIRLAMRSVKLFENFEEDVGM
DIEYYQGGYLLLAYTDEEVGFFEKNVKMQQEEGLDVRILTKQEIERMFPFMNSEGVKLATYCPTDGHANPHLATFAYARA
AERMGAKIYTHTEATGIDVANGQIIGVQTSKSYIKTSVVINAAGGYSREVGLMAGVELPTESYRHQIFVTEPLEHILDPL
VISFENNFYIRQTKSGNFIMGQGDKDEPPSHNHNPSWRFLKEMTQKMPKFFPFLEDVRVLKHWAGLYNMSPDAQPIIDKA
DNVQDFYFAVGFSGHGFMLAPAVGEALAEWIVYGKPKKVDISNLKIDRFAKGVSREKNVV
>Mature_380_residues
MNERASVVIIGGGIIGTAIAFYLCKNGMNDVVVLEKNYLSSGATGRCGGGIRQQWSERMNIRLAMRSVKLFENFEEDVGM
DIEYYQGGYLLLAYTDEEVGFFEKNVKMQQEEGLDVRILTKQEIERMFPFMNSEGVKLATYCPTDGHANPHLATFAYARA
AERMGAKIYTHTEATGIDVANGQIIGVQTSKSYIKTSVVINAAGGYSREVGLMAGVELPTESYRHQIFVTEPLEHILDPL
VISFENNFYIRQTKSGNFIMGQGDKDEPPSHNHNPSWRFLKEMTQKMPKFFPFLEDVRVLKHWAGLYNMSPDAQPIIDKA
DNVQDFYFAVGFSGHGFMLAPAVGEALAEWIVYGKPKKVDISNLKIDRFAKGVSREKNVV

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=400, Percent_Identity=28.25, Blast_Score=174, Evalue=8e-44,
Organism=Homo sapiens, GI197927446, Length=388, Percent_Identity=27.319587628866, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI21361378, Length=388, Percent_Identity=27.319587628866, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI194306651, Length=381, Percent_Identity=26.7716535433071, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI8923708, Length=409, Percent_Identity=26.6503667481663, Blast_Score=142, Evalue=4e-34,
Organism=Escherichia coli, GI1787438, Length=426, Percent_Identity=19.7183098591549, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17541536, Length=427, Percent_Identity=25.2927400468384, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI32563613, Length=390, Percent_Identity=23.8461538461538, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994045, Length=375, Percent_Identity=22.6666666666667, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994052, Length=382, Percent_Identity=22.2513089005236, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI20129729, Length=414, Percent_Identity=27.2946859903382, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI20130091, Length=376, Percent_Identity=24.468085106383, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28571104, Length=390, Percent_Identity=23.5897435897436, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17985989, Length=383, Percent_Identity=23.7597911227154, Blast_Score=101, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 42605; Mature: 42605

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERASVVIIGGGIIGTAIAFYLCKNGMNDVVVLEKNYLSSGATGRCGGGIRQQWSERMN
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
IRLAMRSVKLFENFEEDVGMDIEYYQGGYLLLAYTDEEVGFFEKNVKMQQEEGLDVRILT
EEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHHHHCCCCHHHCCCCEEEEC
KQEIERMFPFMNSEGVKLATYCPTDGHANPHLATFAYARAAERMGAKIYTHTEATGIDVA
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEC
NGQIIGVQTSKSYIKTSVVINAAGGYSREVGLMAGVELPTESYRHQIFVTEPLEHILDPL
CCEEEEEECCCHHEEEEEEEECCCCCCCCCCEEECCCCCCHHHCEEEEEECHHHHHHCCE
VISFENNFYIRQTKSGNFIMGQGDKDEPPSHNHNPSWRFLKEMTQKMPKFFPFLEDVRVL
EEEECCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
KHWAGLYNMSPDAQPIIDKADNVQDFYFAVGFSGHGFMLAPAVGEALAEWIVYGKPKKVD
HHHHHHCCCCCCCCHHHCCCCCCCEEEEEEEECCCCEEECHHHHHHHHHHHHCCCCCEEE
ISNLKIDRFAKGVSREKNVV
CCCCCHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNERASVVIIGGGIIGTAIAFYLCKNGMNDVVVLEKNYLSSGATGRCGGGIRQQWSERMN
CCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHC
IRLAMRSVKLFENFEEDVGMDIEYYQGGYLLLAYTDEEVGFFEKNVKMQQEEGLDVRILT
EEHHHHHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCHHHHCCCCHHHCCCCEEEEC
KQEIERMFPFMNSEGVKLATYCPTDGHANPHLATFAYARAAERMGAKIYTHTEATGIDVA
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCEEEC
NGQIIGVQTSKSYIKTSVVINAAGGYSREVGLMAGVELPTESYRHQIFVTEPLEHILDPL
CCEEEEEECCCHHEEEEEEEECCCCCCCCCCEEECCCCCCHHHCEEEEEECHHHHHHCCE
VISFENNFYIRQTKSGNFIMGQGDKDEPPSHNHNPSWRFLKEMTQKMPKFFPFLEDVRVL
EEEECCCEEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
KHWAGLYNMSPDAQPIIDKADNVQDFYFAVGFSGHGFMLAPAVGEALAEWIVYGKPKKVD
HHHHHHCCCCCCCCHHHCCCCCCCEEEEEEEECCCCEEECHHHHHHHHHHHHCCCCCEEE
ISNLKIDRFAKGVSREKNVV
CCCCCHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]