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The map label for this gene is fabF [H]

Identifier: 239617363

GI number: 239617363

Start: 1026689

End: 1027915

Strand: Direct

Name: fabF [H]

Synonym: Kole_0973

Alternate gene names: 239617363

Gene position: 1026689-1027915 (Clockwise)

Preceding gene: 239617362

Following gene: 239617364

Centisome position: 44.6

GC content: 45.88

Gene sequence:

>1227_bases
ATGGGGAGAAGAGTTGTAGTTACCGGGCTAGGCATCGTTAGCCCGATCGGAAACAACGTACCGGAATTCTGGAACTCTCT
GGAGAACGGCATTTCCGGGATAGATTGGGTTAAAGCCTTTGATGCATCAGAATATCATTCAAAAGTAGCCGGAGAAGTTA
AGAACTTTGATCCTACCCAATACATGGATCGCAAAGAAGCCAGACGAACCTCCAGATTCATTCAACTTGCGGTGGCAAGC
GCTACGCAGGCTATTGAAGACAGTGGATTAAATCCTGATGAAATCCCACCATATCGCTCCGGGGTTGTTTATGGCGTTGG
TATGGGGGCTCTTGACCTGATCGAAGAGCAACACAAAGTATTGTTGAACAAAGGGCCAAGAAGAGTGAGTCCATTCTTCA
TACCAATGACTATTTCAAATATGGCCTCAGGAACCCTCGCAATAAAATTTGGCTTCAAAGGGGTTAATATAACGGTTACC
ACTGCCTGCGCATCAAGTACCAACGCTATTGGTGAAGCCTACAGAATGATTCGAGACGGCATACTGGATGTAGCACTGAC
GGGAGGTGCGGAATCCACGATCACTCCTCTTGCATTTGCAGGATTTGGCTCAATGACCGCACTTTCTACCAAACCACCCG
ACGAAGCATGCCGACCATTTGATGCTAATCGCGATGGTTTTATCATAGCAGAAGGCTCAGCAACGCTTGTACTCGAAGAA
TACGAACACGCCAAAAAAAGAGGTGCAAAAATCTACGCAGAGATAGCTGGTTATGGTGCCACAGATGATGCCAATCACAT
GACAGCTCCAGATTTGGAGGGTACTTCAGCGGCTATGGCTATGAGACTCGCACTTGAAAGTGCGAAAGTGAATCCTGAAG
AAGTAGACTACATAAACGCTCATGGAACCTCAACTCCATTAAACGATAAAACAGAAACCAGAGCAATCAAAAAGGTCTTT
GGGAAGAGAAAAGATCTCAATATAAGTTCTACAAAGTCCATGCATGGCCATGCTCTGGGTGCCGCCGGAGCGCTTGAGGC
AGTAGCGACGGTACTCGCCATAATAAATGAAACCGTTCCACCTACCATAAACCTAAAAACCCCGGATCCGGAATGTGATT
TAAACTATACCCCAAATACCGCTGTTAAAAAGAAAATACGCTGTGCTCTGAGTAACTCATTTGGATTTGGTGGGCATAAC
GCTTCAGTACTCTTCAAAAGGATCTGA

Upstream 100 bases:

>100_bases
ATGAATTCGGCGTACAGATAAGCGATGAAGAGGCAGGAGCACTGAAAACCGTCAAAGACGCCGTTGAGTACCTGAAAAAA
CTGGGGGTGGAATAAATAAA

Downstream 100 bases:

>100_bases
AAAGGCTGACCGGAATTCTCCGGTCGGTCTCTTTTTATTCCTAAAGAATCCTCTCATTCTTTCCTTTCGTCAAGGCAAGT
ACTCAATGAAATGGTTTCTT

Product: 3-oxoacyl-(acyl-carrier-protein) synthase 2

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MGRRVVVTGLGIVSPIGNNVPEFWNSLENGISGIDWVKAFDASEYHSKVAGEVKNFDPTQYMDRKEARRTSRFIQLAVAS
ATQAIEDSGLNPDEIPPYRSGVVYGVGMGALDLIEEQHKVLLNKGPRRVSPFFIPMTISNMASGTLAIKFGFKGVNITVT
TACASSTNAIGEAYRMIRDGILDVALTGGAESTITPLAFAGFGSMTALSTKPPDEACRPFDANRDGFIIAEGSATLVLEE
YEHAKKRGAKIYAEIAGYGATDDANHMTAPDLEGTSAAMAMRLALESAKVNPEEVDYINAHGTSTPLNDKTETRAIKKVF
GKRKDLNISSTKSMHGHALGAAGALEAVATVLAIINETVPPTINLKTPDPECDLNYTPNTAVKKKIRCALSNSFGFGGHN
ASVLFKRI

Sequences:

>Translated_408_residues
MGRRVVVTGLGIVSPIGNNVPEFWNSLENGISGIDWVKAFDASEYHSKVAGEVKNFDPTQYMDRKEARRTSRFIQLAVAS
ATQAIEDSGLNPDEIPPYRSGVVYGVGMGALDLIEEQHKVLLNKGPRRVSPFFIPMTISNMASGTLAIKFGFKGVNITVT
TACASSTNAIGEAYRMIRDGILDVALTGGAESTITPLAFAGFGSMTALSTKPPDEACRPFDANRDGFIIAEGSATLVLEE
YEHAKKRGAKIYAEIAGYGATDDANHMTAPDLEGTSAAMAMRLALESAKVNPEEVDYINAHGTSTPLNDKTETRAIKKVF
GKRKDLNISSTKSMHGHALGAAGALEAVATVLAIINETVPPTINLKTPDPECDLNYTPNTAVKKKIRCALSNSFGFGGHN
ASVLFKRI
>Mature_407_residues
GRRVVVTGLGIVSPIGNNVPEFWNSLENGISGIDWVKAFDASEYHSKVAGEVKNFDPTQYMDRKEARRTSRFIQLAVASA
TQAIEDSGLNPDEIPPYRSGVVYGVGMGALDLIEEQHKVLLNKGPRRVSPFFIPMTISNMASGTLAIKFGFKGVNITVTT
ACASSTNAIGEAYRMIRDGILDVALTGGAESTITPLAFAGFGSMTALSTKPPDEACRPFDANRDGFIIAEGSATLVLEEY
EHAKKRGAKIYAEIAGYGATDDANHMTAPDLEGTSAAMAMRLALESAKVNPEEVDYINAHGTSTPLNDKTETRAIKKVFG
KRKDLNISSTKSMHGHALGAAGALEAVATVLAIINETVPPTINLKTPDPECDLNYTPNTAVKKKIRCALSNSFGFGGHNA
SVLFKRI

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=44.0963855421687, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI223972627, Length=148, Percent_Identity=52.027027027027, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI41872631, Length=421, Percent_Identity=27.5534441805226, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1787337, Length=410, Percent_Identity=50.2439024390244, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=40.8212560386473, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI71983541, Length=410, Percent_Identity=33.9024390243902, Blast_Score=241, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=38.28125, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI212642053, Length=424, Percent_Identity=28.5377358490566, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17550940, Length=409, Percent_Identity=23.4718826405868, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=443, Percent_Identity=36.568848758465, Blast_Score=277, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24644341, Length=414, Percent_Identity=42.9951690821256, Blast_Score=314, Evalue=6e-86,
Organism=Drosophila melanogaster, GI24581345, Length=422, Percent_Identity=27.7251184834123, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI19920632, Length=430, Percent_Identity=26.5116279069767, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI221330659, Length=430, Percent_Identity=26.5116279069767, Blast_Score=135, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43617; Mature: 43486

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRVVVTGLGIVSPIGNNVPEFWNSLENGISGIDWVKAFDASEYHSKVAGEVKNFDPTQ
CCCEEEEECCCHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHH
YMDRKEARRTSRFIQLAVASATQAIEDSGLNPDEIPPYRSGVVYGVGMGALDLIEEQHKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
LLNKGPRRVSPFFIPMTISNMASGTLAIKFGFKGVNITVTTACASSTNAIGEAYRMIRDG
HHCCCCCCCCCEEEEEEHHCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHC
ILDVALTGGAESTITPLAFAGFGSMTALSTKPPDEACRPFDANRDGFIIAEGSATLVLEE
CEEEEECCCCCCCCCHHEEECCCCEEECCCCCCHHHCCCCCCCCCCEEEECCCEEEEEHH
YEHAKKRGAKIYAEIAGYGATDDANHMTAPDLEGTSAAMAMRLALESAKVNPEEVDYINA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEC
HGTSTPLNDKTETRAIKKVFGKRKDLNISSTKSMHGHALGAAGALEAVATVLAIINETVP
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PTINLKTPDPECDLNYTPNTAVKKKIRCALSNSFGFGGHNASVLFKRI
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
GRRVVVTGLGIVSPIGNNVPEFWNSLENGISGIDWVKAFDASEYHSKVAGEVKNFDPTQ
CCEEEEECCCHHCCCCCCHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHH
YMDRKEARRTSRFIQLAVASATQAIEDSGLNPDEIPPYRSGVVYGVGMGALDLIEEQHKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
LLNKGPRRVSPFFIPMTISNMASGTLAIKFGFKGVNITVTTACASSTNAIGEAYRMIRDG
HHCCCCCCCCCEEEEEEHHCCCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHC
ILDVALTGGAESTITPLAFAGFGSMTALSTKPPDEACRPFDANRDGFIIAEGSATLVLEE
CEEEEECCCCCCCCCHHEEECCCCEEECCCCCCHHHCCCCCCCCCCEEEECCCEEEEEHH
YEHAKKRGAKIYAEIAGYGATDDANHMTAPDLEGTSAAMAMRLALESAKVNPEEVDYINA
HHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCEEEC
HGTSTPLNDKTETRAIKKVFGKRKDLNISSTKSMHGHALGAAGALEAVATVLAIINETVP
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
PTINLKTPDPECDLNYTPNTAVKKKIRCALSNSFGFGGHNASVLFKRI
CEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]