Click here to switch to the map view.

The map label for this gene is fabD [H]

Identifier: 239617361

GI number: 239617361

Start: 1025419

End: 1026351

Strand: Direct

Name: fabD [H]

Synonym: Kole_0971

Alternate gene names: 239617361

Gene position: 1025419-1026351 (Clockwise)

Preceding gene: 239617360

Following gene: 239617362

Centisome position: 44.54

GC content: 44.05

Gene sequence:

>933_bases
ATGAATGCATGGATATTCGCAGGTCAGGGAAGCCAATACGTTGGAATGGGAAAGGAGCTCTACAAACGCTATCAAACAGC
AAAGAATATTCTGGAACAAGCAAACGATATTCTCGGTTTCGACATATTGAAACTCATGTTTGAAGGACCTCAGGATCAAC
TCACGTTGACCGAAAATGCTCAACCTGCCATTTTAGCCCATAGTTTCGCAATAGCTCAGGTTCTTGAAGAAATGGGAGTA
AAATGTAACATAACAGCCGGCTTTAGCCTTGGTGAAATCACCGCCCTGACTGTTTCTGGAGTACTTTCATACGAAGATGC
TCTTAAGCTAGCTCACTTGAGAGGAAAAGCGATGCAGTCACAGGTACCGGAAGGTGTCGGAAGCATGGCTGCGGTAATTG
GCGTAGACAGCAAAAAAGCCGAGGAGATCTGCAATGAAATCTCTCCGGAAGGTGATCTCGTGGTAGCCAATTACAACTGC
CCGGGCCAGGTAACCATTTCGGGTCTTAAAGAACTTGTTGAAAAAGCAGTGGAAAGGTTCAAAAATGAGGGCGCAAGAAA
AGTGGTTCCGCTCAGAGTCAGCGCCCCTTTCCACACAAAATTTCTAAAACCTGTTGGAGATACCCTTTTAGACTTTCTCA
ACACTATCAACGTTTCCGTTCCAAAAATCCCGGTCATCTCGAATGTAACCACTGAACCCTATCCAGATGATACGAAAAAA
ATCAAAGAACTGGTTGCTTTACAGGCTTACAGCCCTGTGAAATGGGAACAATCCATCAATACAATGCTCGGAATGGGTGT
GGAAAAATTCATTGAAATCGGTCCCGGTAAAACTCTCACCGGATTTATGAGAAGAATCAACAGAAACAGTTTTGCAAAAT
CCACTGATGGAACTGACTTAGAAGAATTGGCCAGAGAACTGGCGGATACATAA

Upstream 100 bases:

>100_bases
CCGGAATGATAAAGGATATAAAACCCGTAAAAGAAATCATCACTGATTTAATTGAAGAAGCCAATAACGTACTTGCCAGT
CTCCACGGAGGTGTAACCGC

Downstream 100 bases:

>100_bases
GTTTAGCAGTAATGTTTTACATATCACAGTTCAGATGTACACAACAGATAGTGGATAGCCCCATAAAATCATAAAACTTC
TTAAGAAAGGAGCTGAAAAA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MNAWIFAGQGSQYVGMGKELYKRYQTAKNILEQANDILGFDILKLMFEGPQDQLTLTENAQPAILAHSFAIAQVLEEMGV
KCNITAGFSLGEITALTVSGVLSYEDALKLAHLRGKAMQSQVPEGVGSMAAVIGVDSKKAEEICNEISPEGDLVVANYNC
PGQVTISGLKELVEKAVERFKNEGARKVVPLRVSAPFHTKFLKPVGDTLLDFLNTINVSVPKIPVISNVTTEPYPDDTKK
IKELVALQAYSPVKWEQSINTMLGMGVEKFIEIGPGKTLTGFMRRINRNSFAKSTDGTDLEELARELADT

Sequences:

>Translated_310_residues
MNAWIFAGQGSQYVGMGKELYKRYQTAKNILEQANDILGFDILKLMFEGPQDQLTLTENAQPAILAHSFAIAQVLEEMGV
KCNITAGFSLGEITALTVSGVLSYEDALKLAHLRGKAMQSQVPEGVGSMAAVIGVDSKKAEEICNEISPEGDLVVANYNC
PGQVTISGLKELVEKAVERFKNEGARKVVPLRVSAPFHTKFLKPVGDTLLDFLNTINVSVPKIPVISNVTTEPYPDDTKK
IKELVALQAYSPVKWEQSINTMLGMGVEKFIEIGPGKTLTGFMRRINRNSFAKSTDGTDLEELARELADT
>Mature_310_residues
MNAWIFAGQGSQYVGMGKELYKRYQTAKNILEQANDILGFDILKLMFEGPQDQLTLTENAQPAILAHSFAIAQVLEEMGV
KCNITAGFSLGEITALTVSGVLSYEDALKLAHLRGKAMQSQVPEGVGSMAAVIGVDSKKAEEICNEISPEGDLVVANYNC
PGQVTISGLKELVEKAVERFKNEGARKVVPLRVSAPFHTKFLKPVGDTLLDFLNTINVSVPKIPVISNVTTEPYPDDTKK
IKELVALQAYSPVKWEQSINTMLGMGVEKFIEIGPGKTLTGFMRRINRNSFAKSTDGTDLEELARELADT

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=32.7044025157233, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI27477045, Length=106, Percent_Identity=37.7358490566038, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI41872631, Length=216, Percent_Identity=27.3148148148148, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1787334, Length=286, Percent_Identity=40.9090909090909, Blast_Score=210, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=30.0341296928328, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=28.2758620689655, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=296, Percent_Identity=27.3648648648649, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=35.1170568561873, Blast_Score=168, Evalue=4e-42,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33827; Mature: 33827

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAWIFAGQGSQYVGMGKELYKRYQTAKNILEQANDILGFDILKLMFEGPQDQLTLTENA
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAILAHSFAIAQVLEEMGVKCNITAGFSLGEITALTVSGVLSYEDALKLAHLRGKAMQS
CCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVPEGVGSMAAVIGVDSKKAEEICNEISPEGDLVVANYNCPGQVTISGLKELVEKAVERF
HCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHH
KNEGARKVVPLRVSAPFHTKFLKPVGDTLLDFLNTINVSVPKIPVISNVTTEPYPDDTKK
HCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
IKELVALQAYSPVKWEQSINTMLGMGVEKFIEIGPGKTLTGFMRRINRNSFAKSTDGTDL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCH
EELARELADT
HHHHHHHCCC
>Mature Secondary Structure
MNAWIFAGQGSQYVGMGKELYKRYQTAKNILEQANDILGFDILKLMFEGPQDQLTLTENA
CCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
QPAILAHSFAIAQVLEEMGVKCNITAGFSLGEITALTVSGVLSYEDALKLAHLRGKAMQS
CCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVPEGVGSMAAVIGVDSKKAEEICNEISPEGDLVVANYNCPGQVTISGLKELVEKAVERF
HCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHH
KNEGARKVVPLRVSAPFHTKFLKPVGDTLLDFLNTINVSVPKIPVISNVTTEPYPDDTKK
HCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
IKELVALQAYSPVKWEQSINTMLGMGVEKFIEIGPGKTLTGFMRRINRNSFAKSTDGTDL
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCH
EELARELADT
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]