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The map label for this gene is ywlC [H]

Identifier: 239617335

GI number: 239617335

Start: 997777

End: 998805

Strand: Reverse

Name: ywlC [H]

Synonym: Kole_0944

Alternate gene names: 239617335

Gene position: 998805-997777 (Counterclockwise)

Preceding gene: 239617336

Following gene: 239617333

Centisome position: 43.39

GC content: 44.41

Gene sequence:

>1029_bases
TTGAAAACGGAAAAACTGTTCGTTGATACGAACAAGCCGGACAAAGGTATTATTTTAAGAGCCGCCAGGTATTTGCAGAA
GGGAGAACTCGTTGCTTTTCCAACAGAAACGGTTTACGGTCTTGGGGCGAATGCTCTGGATGCCAAAGCGGCTAGCAAGA
TCTTTGAGGCAAAGGGGAGACCACAGGATAATCCTTTGATAGTACATGTCTCATCAATTGAAATGGCTCAAGAACTCGTT
TTAGATGACTTGAATGATTACAAGTGGCTTGTAGAACTTCTCTGGCCGGGGCCTGTAACCATAATCTTCAGAAAATCCAG
GAGAATTCCTGATATCGTTACTGCAGGGTTGCCCAATGTAGGAATAAGATTTCCCAGCCATCCTGTGGCCCAAAAACTCA
TAGAGATTGCAGGATTGCCCATAGCAGCACCGAGCGCAAATCTTTCCGGCAGACCAAGCCCTACCGATGAATTTCACGTG
ATTGAGGATATGGATGGAAGAATTGCATGTATGCTTTTAGCAGGAAAGACACTTTTTGGTTTAGAATCCACCATCGTAGA
TCTAAGCAGGGGAAAACCAACACTTTTGAGACCGGGGCCTATTTCTGTCGAGAGGCTTAAAACGCTTTTCCCGGATCTGG
AGGTTCCAGAATTCGTGAAAGCGGAAGAAAAGTACTCAGGACCGGCTCTTGCACCCGGGATGAAATATAGACATTATTCT
CCGAAGATAGAGTTGATACTTGTTGAAGGTGATCCTCGGGAACGTTATAAGGAGATCATAACCTTCGCTTTTGAAAAAAA
CTCAATCATACTCTGTTCCAGAGAAACAGAACACCTTTATCCGGGAGAGATCAAGAGAAGGGTTTTAGGTTCTAGGGATA
ATCTATACGAGGTTGCGGCGAATCTATTTTATGCACTTCGTGAACCAGGTGAAGAATTCGAACGGATAGTAAGCGAAGCA
TTTCCGGAGACTGGTGTAGGACTTGCCATAATGAACAGATTAAGAAAGGCCGCCTGGAGGATTATGTAA

Upstream 100 bases:

>100_bases
TGCTCGGAACCTCACTCCTGATACCAGATGTCCCTGACATCGTCGGTGCTTACGGAGCGGCACTCATTGCCATGGAGAGA
ATGGAGGAGAGTGAGCGGTT

Downstream 100 bases:

>100_bases
AGGCGGCCATAGTATCAGCAAAAGACTTTCTGTGATAACTAATTTCTCATTCACTTAATTTTTGTCTATAAAAATCCAGG
GAGACATCTTTAAGTGTCAT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKTEKLFVDTNKPDKGIILRAARYLQKGELVAFPTETVYGLGANALDAKAASKIFEAKGRPQDNPLIVHVSSIEMAQELV
LDDLNDYKWLVELLWPGPVTIIFRKSRRIPDIVTAGLPNVGIRFPSHPVAQKLIEIAGLPIAAPSANLSGRPSPTDEFHV
IEDMDGRIACMLLAGKTLFGLESTIVDLSRGKPTLLRPGPISVERLKTLFPDLEVPEFVKAEEKYSGPALAPGMKYRHYS
PKIELILVEGDPRERYKEIITFAFEKNSIILCSRETEHLYPGEIKRRVLGSRDNLYEVAANLFYALREPGEEFERIVSEA
FPETGVGLAIMNRLRKAAWRIM

Sequences:

>Translated_342_residues
MKTEKLFVDTNKPDKGIILRAARYLQKGELVAFPTETVYGLGANALDAKAASKIFEAKGRPQDNPLIVHVSSIEMAQELV
LDDLNDYKWLVELLWPGPVTIIFRKSRRIPDIVTAGLPNVGIRFPSHPVAQKLIEIAGLPIAAPSANLSGRPSPTDEFHV
IEDMDGRIACMLLAGKTLFGLESTIVDLSRGKPTLLRPGPISVERLKTLFPDLEVPEFVKAEEKYSGPALAPGMKYRHYS
PKIELILVEGDPRERYKEIITFAFEKNSIILCSRETEHLYPGEIKRRVLGSRDNLYEVAANLFYALREPGEEFERIVSEA
FPETGVGLAIMNRLRKAAWRIM
>Mature_342_residues
MKTEKLFVDTNKPDKGIILRAARYLQKGELVAFPTETVYGLGANALDAKAASKIFEAKGRPQDNPLIVHVSSIEMAQELV
LDDLNDYKWLVELLWPGPVTIIFRKSRRIPDIVTAGLPNVGIRFPSHPVAQKLIEIAGLPIAAPSANLSGRPSPTDEFHV
IEDMDGRIACMLLAGKTLFGLESTIVDLSRGKPTLLRPGPISVERLKTLFPDLEVPEFVKAEEKYSGPALAPGMKYRHYS
PKIELILVEGDPRERYKEIITFAFEKNSIILCSRETEHLYPGEIKRRVLGSRDNLYEVAANLFYALREPGEEFERIVSEA
FPETGVGLAIMNRLRKAAWRIM

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=197, Percent_Identity=33.502538071066, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI2367210, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081864, Length=205, Percent_Identity=22.4390243902439, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=173, Percent_Identity=31.2138728323699, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=378, Percent_Identity=37.3015873015873, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI78707274, Length=146, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 38262; Mature: 38262

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTEKLFVDTNKPDKGIILRAARYLQKGELVAFPTETVYGLGANALDAKAASKIFEAKGR
CCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHCCC
PQDNPLIVHVSSIEMAQELVLDDLNDYKWLVELLWPGPVTIIFRKSRRIPDIVTAGLPNV
CCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCC
GIRFPSHPVAQKLIEIAGLPIAAPSANLSGRPSPTDEFHVIEDMDGRIACMLLAGKTLFG
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHC
LESTIVDLSRGKPTLLRPGPISVERLKTLFPDLEVPEFVKAEEKYSGPALAPGMKYRHYS
HHHHHHHHCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEECC
PKIELILVEGDPRERYKEIITFAFEKNSIILCSRETEHLYPGEIKRRVLGSRDNLYEVAA
CCEEEEEEECCHHHHHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHH
NLFYALREPGEEFERIVSEAFPETGVGLAIMNRLRKAAWRIM
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTEKLFVDTNKPDKGIILRAARYLQKGELVAFPTETVYGLGANALDAKAASKIFEAKGR
CCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHCCC
PQDNPLIVHVSSIEMAQELVLDDLNDYKWLVELLWPGPVTIIFRKSRRIPDIVTAGLPNV
CCCCCEEEEECHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHCCCCCC
GIRFPSHPVAQKLIEIAGLPIAAPSANLSGRPSPTDEFHVIEDMDGRIACMLLAGKTLFG
CCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHC
LESTIVDLSRGKPTLLRPGPISVERLKTLFPDLEVPEFVKAEEKYSGPALAPGMKYRHYS
HHHHHHHHCCCCCCEECCCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEECC
PKIELILVEGDPRERYKEIITFAFEKNSIILCSRETEHLYPGEIKRRVLGSRDNLYEVAA
CCEEEEEEECCHHHHHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHH
NLFYALREPGEEFERIVSEAFPETGVGLAIMNRLRKAAWRIM
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]