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The map label for this gene is yegE [H]

Identifier: 239617314

GI number: 239617314

Start: 976787

End: 977698

Strand: Reverse

Name: yegE [H]

Synonym: Kole_0923

Alternate gene names: 239617314

Gene position: 977698-976787 (Counterclockwise)

Preceding gene: 239617318

Following gene: 239617312

Centisome position: 42.47

GC content: 39.58

Gene sequence:

>912_bases
ATGTCAGGCAATGATCATGATTACAGGCATTGGAGGGGTTTACTTGATGTACTAATCGAAGGAGCTTATATTGTTGATAA
GCACAGAAAAATACTTTACTGGAACAAAGCAGCAGAAAAGATAACCAGCTACCGTAAAGATGAAATTCTGGGAAGATCCT
GTATGGATAATATCCTTATGCATGTTGACGAAGCGGGAAATAGTCTTTGTAAAGGAGATTGCCCGCTTGCAAAGACACTT
AAAGATGGAAAGATTAGAGAAGCAAACGTGTATCTTCACCACAAAGATGGTTACAGAAAACCTGTATGTATCAGAGTGGT
TCCACTCAGAAATGACTATGGCGAAATACACGCCGCCCTAGAGCTCTTCAATGACAAAACACCTGAAGAAGCACTTAAAC
AGAGAATGACTGAACTTGAAAAACTTGCCATGTTTGATGAATTGACGAAACTTCCAAACAGACGTTACGTTGAAGAAAGA
TTAGAAGATTTCATGAATGATTTCATGAGGCATAAATTGAGATTCGGTGTAATTTTCATGGATATAGATCATTTCAAAAG
TTTTAATGACACCTATGGCCATGTCGCAGGCGACAAAGTATTGAAGATCGTGGCTAATACGCTTCTCGGTGCCTCAAGAG
TTTCCGATGTTGTCGGTAGATGGGGTGGTGAAGAATTTGTTGCGCTCATCAAAAACGTTAACATGAAAACTATTGAAACA
ATAGCTGAGAGATATCGCCTACTTGTTGAGAGCTCCAGTTTCGAACTAAATGGAGAAAGTTTGAGTGTAACCATCTCGAT
TGGAGCTACCCTTGCAAAACAAGGCGACACAAAAGAGAGTATCATAAAGCGTGCCGATGAGCTGATGTATATAAGTAAAC
AAAGGGGTAGAAACAGGCTTACTATCGGTTAA

Upstream 100 bases:

>100_bases
GATCGATGAAAGGCAAAAACAATAACCGAAAGGAATAGTGATAGAATAAATTTCGAGAAATATACGACAAACAAAAAATT
TTTCAAGAGTGGGTGATAAA

Downstream 100 bases:

>100_bases
TTCACTTTGCTCTTGCTAATTCGGCAACTATTTTGTTTCCCTTTATCTTGCAGCGATTGAGAGAATCAATAACCAATTCA
GCATATCTGCGCTCAACTTC

Product: diguanylate cyclase with PAS/PAC sensor

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSGNDHDYRHWRGLLDVLIEGAYIVDKHRKILYWNKAAEKITSYRKDEILGRSCMDNILMHVDEAGNSLCKGDCPLAKTL
KDGKIREANVYLHHKDGYRKPVCIRVVPLRNDYGEIHAALELFNDKTPEEALKQRMTELEKLAMFDELTKLPNRRYVEER
LEDFMNDFMRHKLRFGVIFMDIDHFKSFNDTYGHVAGDKVLKIVANTLLGASRVSDVVGRWGGEEFVALIKNVNMKTIET
IAERYRLLVESSSFELNGESLSVTISIGATLAKQGDTKESIIKRADELMYISKQRGRNRLTIG

Sequences:

>Translated_303_residues
MSGNDHDYRHWRGLLDVLIEGAYIVDKHRKILYWNKAAEKITSYRKDEILGRSCMDNILMHVDEAGNSLCKGDCPLAKTL
KDGKIREANVYLHHKDGYRKPVCIRVVPLRNDYGEIHAALELFNDKTPEEALKQRMTELEKLAMFDELTKLPNRRYVEER
LEDFMNDFMRHKLRFGVIFMDIDHFKSFNDTYGHVAGDKVLKIVANTLLGASRVSDVVGRWGGEEFVALIKNVNMKTIET
IAERYRLLVESSSFELNGESLSVTISIGATLAKQGDTKESIIKRADELMYISKQRGRNRLTIG
>Mature_302_residues
SGNDHDYRHWRGLLDVLIEGAYIVDKHRKILYWNKAAEKITSYRKDEILGRSCMDNILMHVDEAGNSLCKGDCPLAKTLK
DGKIREANVYLHHKDGYRKPVCIRVVPLRNDYGEIHAALELFNDKTPEEALKQRMTELEKLAMFDELTKLPNRRYVEERL
EDFMNDFMRHKLRFGVIFMDIDHFKSFNDTYGHVAGDKVLKIVANTLLGASRVSDVVGRWGGEEFVALIKNVNMKTIETI
AERYRLLVESSSFELNGESLSVTISIGATLAKQGDTKESIIKRADELMYISKQRGRNRLTIG

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=289, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=36.7088607594937, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082007, Length=229, Percent_Identity=33.6244541484716, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=254, Percent_Identity=32.2834645669291, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787541, Length=292, Percent_Identity=27.3972602739726, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787816, Length=155, Percent_Identity=34.8387096774194, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=36.5853658536585, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787802, Length=174, Percent_Identity=33.9080459770115, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786584, Length=162, Percent_Identity=32.7160493827161, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788085, Length=177, Percent_Identity=32.7683615819209, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788956, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081977, Length=185, Percent_Identity=30.2702702702703, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787056, Length=169, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081974, Length=154, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 34815; Mature: 34683

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNDHDYRHWRGLLDVLIEGAYIVDKHRKILYWNKAAEKITSYRKDEILGRSCMDNILM
CCCCCCHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
HVDEAGNSLCKGDCPLAKTLKDGKIREANVYLHHKDGYRKPVCIRVVPLRNDYGEIHAAL
HHHHHCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHH
ELFNDKTPEEALKQRMTELEKLAMFDELTKLPNRRYVEERLEDFMNDFMRHKLRFGVIFM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEE
DIDHFKSFNDTYGHVAGDKVLKIVANTLLGASRVSDVVGRWGGEEFVALIKNVNMKTIET
EHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
IAERYRLLVESSSFELNGESLSVTISIGATLAKQGDTKESIIKRADELMYISKQRGRNRL
HHHHHHHHHCCCCCEECCCEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
TIG
CCC
>Mature Secondary Structure 
SGNDHDYRHWRGLLDVLIEGAYIVDKHRKILYWNKAAEKITSYRKDEILGRSCMDNILM
CCCCCHHHHHHHHHHHHHCCCCEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
HVDEAGNSLCKGDCPLAKTLKDGKIREANVYLHHKDGYRKPVCIRVVPLRNDYGEIHAAL
HHHHHCCCCCCCCCCHHHHHCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCHHHHHHHH
ELFNDKTPEEALKQRMTELEKLAMFDELTKLPNRRYVEERLEDFMNDFMRHKLRFGVIFM
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEE
DIDHFKSFNDTYGHVAGDKVLKIVANTLLGASRVSDVVGRWGGEEFVALIKNVNMKTIET
EHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
IAERYRLLVESSSFELNGESLSVTISIGATLAKQGDTKESIIKRADELMYISKQRGRNRL
HHHHHHHHHCCCCCEECCCEEEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCC
TIG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]