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The map label for this gene is ykoH [H]

Identifier: 239617307

GI number: 239617307

Start: 968262

End: 969572

Strand: Direct

Name: ykoH [H]

Synonym: Kole_0916

Alternate gene names: 239617307

Gene position: 968262-969572 (Clockwise)

Preceding gene: 239617306

Following gene: 239617310

Centisome position: 42.06

GC content: 39.36

Gene sequence:

>1311_bases
TTGCGAAGGAGTAAATCCATACCATTTTCACTTCAGTTATTTATCAGTATTGTTATGATAACCGTGCTCGTCATGGTTTT
CTTTGCCCTTTTTGTTTATAGTCTTTCATCCGAGCTGTTTGTACGAAATTACGCTACCGAGCTGGAGAAGAATTTTAGAA
ATTTCTTCAACTTTAATGCCCAAAGGCATGGTATAGCATCAGGGCCACGCGGAATGTCGGGTGGACCACAAAGCAGGATT
TCAAAAAGTCTTTTTATTATGGTTGATGATAGTGTACTTCAAAACCCGGATGGAATACCAGCACCGGATTTTTTTGAAGG
ACGAAAACTCCTAAAAATAGATGGAAATACCTACCTGTTCTATGGATTTATAGATTCCGGAAAAAAGGTGCTTTTGGGCA
TAAGAACTGCTGAATACGATTTTCTGCTTGGTGGCTTGAAAAAAGCTTTTATTGTTGCCATTATGTTATCGCTGATTCTT
TCAGGCATTGTGGGATATTATATAAGCTCCAAGATATCGACACCACTTAAAAGAACGATGGAACTCTTAAAAGAAGTTGT
GGTGAGTGATCTTTCAAAGAGAATATCTGTTGACTCTAACACGAAAGAGATATTGGAACTTACTCAGGCGATAAATTCAG
CATTGGACAGGATAGAAGATGGTTATAAAAGGCAGGAGCAGTTTTCCTCTGATGTAGCCCACGAGATACGTTCCCCATTA
ACTGCTATACTTGGTTTTTCACGAATGATACAGCGTTGGGGAGCAAGAGACCCAGAAATCGTTGAAGAATCAGCGAAAAA
TATAGCAGAAACAGCTGCAAAGATGCTTACCCTTACTGAAGGTTTGCTATTTCTTTCGAAACCAAACCTTTCACCAAATC
TGGAAATTTTGAATCTGAGGACCCTGGTAGAAAGAAACGTTTCGGATATCACTAGAATTTATGGAATAAAGATAAAAAAC
GTCGTGCCCGATTTAAATGTAAAAACCGATGAAAGCCTGCTTTCCATAGCTATAAAGATACTCCTGGAGAATGCGGCAAA
ACACGGCGAAGGTAAGCCAGTGGAAATTGGTTGGGATAGCGAAAGAAAGGCTTTATATGTTAGGGATTATGGTCCCGGGA
TACCAGATGAAATTAAGGATAAAATATTTGACAGATTTTTCAAGGCAGAACGCTCAAGAAGCGGTTCTGGACATGGCCTT
GGTTTATCAATTTTCAAAAAGATCTGTGATACGTTGGGATTAACCGTAAAGGTTGAGGATCCACCTGATGGTGGCGCAAG
TTTCGTAATAACAGGCTGGAAATTATCATAA

Upstream 100 bases:

>100_bases
TGGGGGAATCCTAACGTTGTGGAAGTGTACATAAATTATCTGCGAAAGAAACTTGGATCAGCGGGGAAGATCATAAAAAC
GGTAAGAGGTGTTGGTTACG

Downstream 100 bases:

>100_bases
CAACGGTAAAATCAAAAACGTTTTTCTACGAGTTCAAGGGCGATTCTTTCCCTTTCGAGGTCAATACTCAGAACTTTTAC
TTTTACAATCTGTCCAACAG

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MRRSKSIPFSLQLFISIVMITVLVMVFFALFVYSLSSELFVRNYATELEKNFRNFFNFNAQRHGIASGPRGMSGGPQSRI
SKSLFIMVDDSVLQNPDGIPAPDFFEGRKLLKIDGNTYLFYGFIDSGKKVLLGIRTAEYDFLLGGLKKAFIVAIMLSLIL
SGIVGYYISSKISTPLKRTMELLKEVVVSDLSKRISVDSNTKEILELTQAINSALDRIEDGYKRQEQFSSDVAHEIRSPL
TAILGFSRMIQRWGARDPEIVEESAKNIAETAAKMLTLTEGLLFLSKPNLSPNLEILNLRTLVERNVSDITRIYGIKIKN
VVPDLNVKTDESLLSIAIKILLENAAKHGEGKPVEIGWDSERKALYVRDYGPGIPDEIKDKIFDRFFKAERSRSGSGHGL
GLSIFKKICDTLGLTVKVEDPPDGGASFVITGWKLS

Sequences:

>Translated_436_residues
MRRSKSIPFSLQLFISIVMITVLVMVFFALFVYSLSSELFVRNYATELEKNFRNFFNFNAQRHGIASGPRGMSGGPQSRI
SKSLFIMVDDSVLQNPDGIPAPDFFEGRKLLKIDGNTYLFYGFIDSGKKVLLGIRTAEYDFLLGGLKKAFIVAIMLSLIL
SGIVGYYISSKISTPLKRTMELLKEVVVSDLSKRISVDSNTKEILELTQAINSALDRIEDGYKRQEQFSSDVAHEIRSPL
TAILGFSRMIQRWGARDPEIVEESAKNIAETAAKMLTLTEGLLFLSKPNLSPNLEILNLRTLVERNVSDITRIYGIKIKN
VVPDLNVKTDESLLSIAIKILLENAAKHGEGKPVEIGWDSERKALYVRDYGPGIPDEIKDKIFDRFFKAERSRSGSGHGL
GLSIFKKICDTLGLTVKVEDPPDGGASFVITGWKLS
>Mature_436_residues
MRRSKSIPFSLQLFISIVMITVLVMVFFALFVYSLSSELFVRNYATELEKNFRNFFNFNAQRHGIASGPRGMSGGPQSRI
SKSLFIMVDDSVLQNPDGIPAPDFFEGRKLLKIDGNTYLFYGFIDSGKKVLLGIRTAEYDFLLGGLKKAFIVAIMLSLIL
SGIVGYYISSKISTPLKRTMELLKEVVVSDLSKRISVDSNTKEILELTQAINSALDRIEDGYKRQEQFSSDVAHEIRSPL
TAILGFSRMIQRWGARDPEIVEESAKNIAETAAKMLTLTEGLLFLSKPNLSPNLEILNLRTLVERNVSDITRIYGIKIKN
VVPDLNVKTDESLLSIAIKILLENAAKHGEGKPVEIGWDSERKALYVRDYGPGIPDEIKDKIFDRFFKAERSRSGSGHGL
GLSIFKKICDTLGLTVKVEDPPDGGASFVITGWKLS

Specific function: Probable member of the two-component regulatory system ykoH/ykoG. Potentially phosphorylates ykoG [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=298, Percent_Identity=28.1879194630872, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=28.4584980237154, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788393, Length=278, Percent_Identity=27.3381294964029, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=27.9151943462898, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=251, Percent_Identity=26.2948207171315, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789403, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=278, Percent_Identity=28.0575539568345, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=267, Percent_Identity=23.9700374531835, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=26.5232974910394, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=214, Percent_Identity=27.5700934579439, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=238, Percent_Identity=26.0504201680672, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48636; Mature: 48636

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSKSIPFSLQLFISIVMITVLVMVFFALFVYSLSSELFVRNYATELEKNFRNFFNFNA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QRHGIASGPRGMSGGPQSRISKSLFIMVDDSVLQNPDGIPAPDFFEGRKLLKIDGNTYLF
CCCCCCCCCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEEECCCEEEE
YGFIDSGKKVLLGIRTAEYDFLLGGLKKAFIVAIMLSLILSGIVGYYISSKISTPLKRTM
EEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELLKEVVVSDLSKRISVDSNTKEILELTQAINSALDRIEDGYKRQEQFSSDVAHEIRSPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAILGFSRMIQRWGARDPEIVEESAKNIAETAAKMLTLTEGLLFLSKPNLSPNLEILNLR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEHHH
TLVERNVSDITRIYGIKIKNVVPDLNVKTDESLLSIAIKILLENAAKHGEGKPVEIGWDS
HHHHCCHHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
ERKALYVRDYGPGIPDEIKDKIFDRFFKAERSRSGSGHGLGLSIFKKICDTLGLTVKVED
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECC
PPDGGASFVITGWKLS
CCCCCCEEEEECCEEC
>Mature Secondary Structure
MRRSKSIPFSLQLFISIVMITVLVMVFFALFVYSLSSELFVRNYATELEKNFRNFFNFNA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QRHGIASGPRGMSGGPQSRISKSLFIMVDDSVLQNPDGIPAPDFFEGRKLLKIDGNTYLF
CCCCCCCCCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCCCCCCCEEEEECCCEEEE
YGFIDSGKKVLLGIRTAEYDFLLGGLKKAFIVAIMLSLILSGIVGYYISSKISTPLKRTM
EEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELLKEVVVSDLSKRISVDSNTKEILELTQAINSALDRIEDGYKRQEQFSSDVAHEIRSPL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAILGFSRMIQRWGARDPEIVEESAKNIAETAAKMLTLTEGLLFLSKPNLSPNLEILNLR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEEHHH
TLVERNVSDITRIYGIKIKNVVPDLNVKTDESLLSIAIKILLENAAKHGEGKPVEIGWDS
HHHHCCHHHHHHHHCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCC
ERKALYVRDYGPGIPDEIKDKIFDRFFKAERSRSGSGHGLGLSIFKKICDTLGLTVKVED
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEECC
PPDGGASFVITGWKLS
CCCCCCEEEEECCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]