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The map label for this gene is glmS [H]

Identifier: 239617132

GI number: 239617132

Start: 786073

End: 787074

Strand: Direct

Name: glmS [H]

Synonym: Kole_0736

Alternate gene names: 239617132

Gene position: 786073-787074 (Clockwise)

Preceding gene: 239617131

Following gene: 239617133

Centisome position: 34.15

GC content: 40.12

Gene sequence:

>1002_bases
GTGACAACTGTCGAGAAAGAAATACGCGAGCAGATAACCGATCTTCCAAATATACTCAGTTTTATGAAAGATTTTGTCAA
AACAGGGAAATTACCGGATTTTCTGTTTGATGCAGACCTGGTCTATTTTGTCGGATGTGGAAGTTCCCATTACAATGGTA
TAGCTGCATCTCGTTATTTTATCCAAAAAACAGGAATAGAAGCCAGAGCACTGCCGGGCGGTGAAATCTTCTTTGCAAAA
AATCAAAATATAGGCAGTAACACAATGAAGAGAGCAGCTGTGCTTATTTCTAGATCTGGAGAATCAACAGAAGTTCTGCT
TGCCGGGAAGGTTTTCAAGCAACTTGGAATACCGACGCTGGGAATAACAACGGTAAATAACAGTTCTCTTGTAAAGATAG
TTGATCGTTCTATTGTACTGCCTCTCGATGAAGTTTCCATAGTTATGACGAAGTCGTTTTCCGCTATTCTTCTAGCTTTA
CAGTTACTTGTTGACTATTATTCCAATGGGAATTTCGAGTATTACGATGAATTAGTCCGTTTGATACCGGACATAATTGA
GAAAAGTTTTGAAATGATTGAGAATGACCAGCTGTGTTCTTACAAACGTTTCATCTTTCTTGGTATAGGTTCCTTTGAGG
GGATTGCCAGAGAAGGTGCTTTGAAACTGGAAGAGATGTCTCTGAGCACAACAAAGGCTTTCTCAACCTATGAATTCAGG
CACGGACCTAAATCGATGGCAGATGAAGAAACACTCGTCACGATTTTCGGAGATATCACAACAGAAGAAAGAAAACTCGC
GGATGAGTTAAGATCTTACGGATCAAAGATAATTTATGTTGGTTCAGGTGAACCTGATATCTATACGGGTGGAGAAATGG
GACTATTCCTGTCTCCTATTTTCTCACAGATATTGGGGTTAAAAATTGCTGAAGCAAAGGGCTTGAACGTTGAAGCTCCA
AGGAATCTTACAAAGGTTGTACGCTTTGTGCACAACGCGTGA

Upstream 100 bases:

>100_bases
GTTTTATCTTTTTGTTCATATATAATCAAACTTACCCATGTTTACTAGTTATATATGATTGTTTTTGGAAAGTACAGGAT
GATGAAAGGAGTGAAATACC

Downstream 100 bases:

>100_bases
TTGATTAAATTTTCAGATCAATGAAAGTAAGATACTAAAGCCCGGAGGTGAAGTTATGAATCTTACGGTAGGAAAGTTCA
GAGGTTATACCAGGATTTCC

Product: Glutamine--fructose-6-phosphate transaminase (isomerizing)

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTVEKEIREQITDLPNILSFMKDFVKTGKLPDFLFDADLVYFVGCGSSHYNGIAASRYFIQKTGIEARALPGGEIFFAK
NQNIGSNTMKRAAVLISRSGESTEVLLAGKVFKQLGIPTLGITTVNNSSLVKIVDRSIVLPLDEVSIVMTKSFSAILLAL
QLLVDYYSNGNFEYYDELVRLIPDIIEKSFEMIENDQLCSYKRFIFLGIGSFEGIAREGALKLEEMSLSTTKAFSTYEFR
HGPKSMADEETLVTIFGDITTEERKLADELRSYGSKIIYVGSGEPDIYTGGEMGLFLSPIFSQILGLKIAEAKGLNVEAP
RNLTKVVRFVHNA

Sequences:

>Translated_333_residues
MTTVEKEIREQITDLPNILSFMKDFVKTGKLPDFLFDADLVYFVGCGSSHYNGIAASRYFIQKTGIEARALPGGEIFFAK
NQNIGSNTMKRAAVLISRSGESTEVLLAGKVFKQLGIPTLGITTVNNSSLVKIVDRSIVLPLDEVSIVMTKSFSAILLAL
QLLVDYYSNGNFEYYDELVRLIPDIIEKSFEMIENDQLCSYKRFIFLGIGSFEGIAREGALKLEEMSLSTTKAFSTYEFR
HGPKSMADEETLVTIFGDITTEERKLADELRSYGSKIIYVGSGEPDIYTGGEMGLFLSPIFSQILGLKIAEAKGLNVEAP
RNLTKVVRFVHNA
>Mature_332_residues
TTVEKEIREQITDLPNILSFMKDFVKTGKLPDFLFDADLVYFVGCGSSHYNGIAASRYFIQKTGIEARALPGGEIFFAKN
QNIGSNTMKRAAVLISRSGESTEVLLAGKVFKQLGIPTLGITTVNNSSLVKIVDRSIVLPLDEVSIVMTKSFSAILLALQ
LLVDYYSNGNFEYYDELVRLIPDIIEKSFEMIENDQLCSYKRFIFLGIGSFEGIAREGALKLEEMSLSTTKAFSTYEFRH
GPKSMADEETLVTIFGDITTEERKLADELRSYGSKIIYVGSGEPDIYTGGEMGLFLSPIFSQILGLKIAEAKGLNVEAPR
NLTKVVRFVHNA

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=360, Percent_Identity=22.5, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4826742, Length=362, Percent_Identity=23.7569060773481, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790167, Length=363, Percent_Identity=26.7217630853994, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17532899, Length=360, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532897, Length=360, Percent_Identity=24.4444444444444, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539970, Length=313, Percent_Identity=25.2396166134185, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322745, Length=364, Percent_Identity=23.6263736263736, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 36949; Mature: 36818

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTVEKEIREQITDLPNILSFMKDFVKTGKLPDFLFDADLVYFVGCGSSHYNGIAASRYF
CCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHH
IQKTGIEARALPGGEIFFAKNQNIGSNTMKRAAVLISRSGESTEVLLAGKVFKQLGIPTL
HHHCCCCEECCCCCEEEEEECCCCCHHHHHHHHHEEECCCCCCEEEEHHHHHHHHCCCEE
GITTVNNSSLVKIVDRSIVLPLDEVSIVMTKSFSAILLALQLLVDYYSNGNFEYYDELVR
EEEEECCCCEEEEECCEEECCHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIPDIIEKSFEMIENDQLCSYKRFIFLGIGSFEGIAREGALKLEEMSLSTTKAFSTYEFR
HHHHHHHHHHHHHCCCCHHCEEEEEEEECCCCCCHHHHCCCCHHHHCCHHHHHHHHHHHC
HGPKSMADEETLVTIFGDITTEERKLADELRSYGSKIIYVGSGEPDIYTGGEMGLFLSPI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHH
FSQILGLKIAEAKGLNVEAPRNLTKVVRFVHNA
HHHHHCCEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TTVEKEIREQITDLPNILSFMKDFVKTGKLPDFLFDADLVYFVGCGSSHYNGIAASRYF
CCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHCCCEEEEEECCCCCCCCHHHHHHH
IQKTGIEARALPGGEIFFAKNQNIGSNTMKRAAVLISRSGESTEVLLAGKVFKQLGIPTL
HHHCCCCEECCCCCEEEEEECCCCCHHHHHHHHHEEECCCCCCEEEEHHHHHHHHCCCEE
GITTVNNSSLVKIVDRSIVLPLDEVSIVMTKSFSAILLALQLLVDYYSNGNFEYYDELVR
EEEEECCCCEEEEECCEEECCHHHHEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LIPDIIEKSFEMIENDQLCSYKRFIFLGIGSFEGIAREGALKLEEMSLSTTKAFSTYEFR
HHHHHHHHHHHHHCCCCHHCEEEEEEEECCCCCCHHHHCCCCHHHHCCHHHHHHHHHHHC
HGPKSMADEETLVTIFGDITTEERKLADELRSYGSKIIYVGSGEPDIYTGGEMGLFLSPI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHH
FSQILGLKIAEAKGLNVEAPRNLTKVVRFVHNA
HHHHHCCEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]