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The map label for this gene is cpg2 [H]

Identifier: 239617131

GI number: 239617131

Start: 784924

End: 785937

Strand: Direct

Name: cpg2 [H]

Synonym: Kole_0735

Alternate gene names: 239617131

Gene position: 784924-785937 (Clockwise)

Preceding gene: 239617130

Following gene: 239617132

Centisome position: 34.1

GC content: 43.79

Gene sequence:

>1014_bases
ATGGATATTCTCGAAAAGCTTGTCAACACAGCTACCGGTCCTGATGTATCCACCGAAGAAAAGCTCAAGAGAACAGCCTT
TCTTCTTGATATTCTGGTGGATTTTGGGTTCAAAGTGCGCAGCGGCAACGGGTGTCACGTTGCCGTACGTGGCAATCCTC
CTTACCTAACCCTCATCGGCCATCTGGACACAGTTTTCCCGGAAGGTGAAGAGAAGAAAAGACCGTTCAGTATTGTTGGT
GATAAAGCGTACGGTCCCGGTGTTGCGGACATGAAGGGCGGTATTGCGGTAATGTTTCAGGCACTCAAGGACATTGACCG
GGACAACATAGCAATAATACTAAACGTTGATGAAGAGATAGGTTCACCAGAAAGTGAGATTGTTTTCAGTGAATTTGCCA
AGAAAACCTCTTACTGCCTTTCATTTGAACCCGCTTTTCCAGATGGAAAACTTGTCGCCTCCAGAAAAGGGGTTGGTGCG
CTCTTAATCAAAACTCACGGAAAAAAGGGACACGCTGCGAGGATACAGGAAGGCGCGAACGCTGTGGTGGAACTCTCAAC
CAAAATCCATAAAATCTGGGAATTGAACAGAAATTTTGTGGATTTAACTGTGAATCCAACGATTATCAAAGGTGGTATCA
AAAGCAATGTAACTCCAGATTACGCGGAATGCTATTGCAACGTCAGATATTACGCGATGAATGAGGTAGAGAAATTCGAA
AAAGAAATCGCCAGAATCTCTAAAGAAACCGTTATTAATGGTTGCACTACGGAATTCGAGTACAAGCAATATAGAAAACC
CATGAAAGAATGCCCTGAACTCGTTGAAATCGTTAGAAAGGAAGGGTTTAAGGTCACACGATCATCTGGAAGCGGTGATG
CGGCATTCTTCAACAGAGCAATCGACGGACTCGGTCTTCCAGGAGGCAATCTTCACTCTGAGGAAGAATACGCTATCATC
TCAGAATTTGATAAAAAGGTCAAACTCGCAAAAAAACTAATTACCTCAATTTAA

Upstream 100 bases:

>100_bases
AGATCCTGAAATACCAGCAGATCTCGAAGGTGTTTTGCCTATACCTATTCCAGATTATGGAGCAGATTTTATTTGAAACT
TAGAAAAGGAGCGTCTTACT

Downstream 100 bases:

>100_bases
GAGTTTTCCCCAAAAGGATAACCTTTTGGGGGTTTGTTTTATCTTTTTGTTCATATATAATCAAACTTACCCATGTTTAC
TAGTTATATATGATTGTTTT

Product: peptidase M20

Products: NA

Alternate protein names: CPDG2; Folate hydrolase G2; Glutamate carboxypeptidase; Pteroylmonoglutamic acid hydrolase G2; Glucarpidase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MDILEKLVNTATGPDVSTEEKLKRTAFLLDILVDFGFKVRSGNGCHVAVRGNPPYLTLIGHLDTVFPEGEEKKRPFSIVG
DKAYGPGVADMKGGIAVMFQALKDIDRDNIAIILNVDEEIGSPESEIVFSEFAKKTSYCLSFEPAFPDGKLVASRKGVGA
LLIKTHGKKGHAARIQEGANAVVELSTKIHKIWELNRNFVDLTVNPTIIKGGIKSNVTPDYAECYCNVRYYAMNEVEKFE
KEIARISKETVINGCTTEFEYKQYRKPMKECPELVEIVRKEGFKVTRSSGSGDAAFFNRAIDGLGLPGGNLHSEEEYAII
SEFDKKVKLAKKLITSI

Sequences:

>Translated_337_residues
MDILEKLVNTATGPDVSTEEKLKRTAFLLDILVDFGFKVRSGNGCHVAVRGNPPYLTLIGHLDTVFPEGEEKKRPFSIVG
DKAYGPGVADMKGGIAVMFQALKDIDRDNIAIILNVDEEIGSPESEIVFSEFAKKTSYCLSFEPAFPDGKLVASRKGVGA
LLIKTHGKKGHAARIQEGANAVVELSTKIHKIWELNRNFVDLTVNPTIIKGGIKSNVTPDYAECYCNVRYYAMNEVEKFE
KEIARISKETVINGCTTEFEYKQYRKPMKECPELVEIVRKEGFKVTRSSGSGDAAFFNRAIDGLGLPGGNLHSEEEYAII
SEFDKKVKLAKKLITSI
>Mature_337_residues
MDILEKLVNTATGPDVSTEEKLKRTAFLLDILVDFGFKVRSGNGCHVAVRGNPPYLTLIGHLDTVFPEGEEKKRPFSIVG
DKAYGPGVADMKGGIAVMFQALKDIDRDNIAIILNVDEEIGSPESEIVFSEFAKKTSYCLSFEPAFPDGKLVASRKGVGA
LLIKTHGKKGHAARIQEGANAVVELSTKIHKIWELNRNFVDLTVNPTIIKGGIKSNVTPDYAECYCNVRYYAMNEVEKFE
KEIARISKETVINGCTTEFEYKQYRKPMKECPELVEIVRKEGFKVTRSSGSGDAAFFNRAIDGLGLPGGNLHSEEEYAII
SEFDKKVKLAKKLITSI

Specific function: Catalyzes the hydrolysis of reduced and non-reduced folates to pteroates and L-glutamate. This enzyme has a broad specificity [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=379, Percent_Identity=26.1213720316623, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR017150
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.17.11 [H]

Molecular weight: Translated: 37262; Mature: 37262

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILEKLVNTATGPDVSTEEKLKRTAFLLDILVDFGFKVRSGNGCHVAVRGNPPYLTLIG
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCEEEEEE
HLDTVFPEGEEKKRPFSIVGDKAYGPGVADMKGGIAVMFQALKDIDRDNIAIILNVDEEI
CHHHCCCCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEEEEEHHHH
GSPESEIVFSEFAKKTSYCLSFEPAFPDGKLVASRKGVGALLIKTHGKKGHAARIQEGAN
CCCHHHHHHHHHHHHHCEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHCCC
AVVELSTKIHKIWELNRNFVDLTVNPTIIKGGIKSNVTPDYAECYCNVRYYAMNEVEKFE
CEEHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCHHHHEECCCEEEHHHHHHHH
KEIARISKETVINGCTTEFEYKQYRKPMKECPELVEIVRKEGFKVTRSSGSGDAAFFNRA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
IDGLGLPGGNLHSEEEYAIISEFDKKVKLAKKLITSI
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDILEKLVNTATGPDVSTEEKLKRTAFLLDILVDFGFKVRSGNGCHVAVRGNPPYLTLIG
CCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCEEEEEE
HLDTVFPEGEEKKRPFSIVGDKAYGPGVADMKGGIAVMFQALKDIDRDNIAIILNVDEEI
CHHHCCCCCCCCCCCEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCCEEEEEEEHHHH
GSPESEIVFSEFAKKTSYCLSFEPAFPDGKLVASRKGVGALLIKTHGKKGHAARIQEGAN
CCCHHHHHHHHHHHHHCEEEEECCCCCCCCEEECCCCCEEEEEEECCCCCCHHHHHHCCC
AVVELSTKIHKIWELNRNFVDLTVNPTIIKGGIKSNVTPDYAECYCNVRYYAMNEVEKFE
CEEHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCHHHHEECCCEEEHHHHHHHH
KEIARISKETVINGCTTEFEYKQYRKPMKECPELVEIVRKEGFKVTRSSGSGDAAFFNRA
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHH
IDGLGLPGGNLHSEEEYAIISEFDKKVKLAKKLITSI
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6396165; 3838935; 9083113 [H]