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The map label for this gene is nagA [H]

Identifier: 239617127

GI number: 239617127

Start: 781591

End: 782676

Strand: Direct

Name: nagA [H]

Synonym: Kole_0731

Alternate gene names: 239617127

Gene position: 781591-782676 (Clockwise)

Preceding gene: 239617126

Following gene: 239617128

Centisome position: 33.95

GC content: 43.19

Gene sequence:

>1086_bases
ATGTTAATCGAGCGAGTGCTGATCGTTGACCCCGTAGACGGAGAATACACCGGGAGCGTGCAATTCGGAGAAAAGATAGA
ACGAATAATGAAAAAAGAAACGGATTACGATTATATACTCATGCCAGGCTTTATAGATCCTCACACGCACGGTCTCGTTG
GAATAGACACGATGGAAGCCTCAAAAGCAGCCTATGAAAAATGGATAAACGAAAACTTTTCTCGGGGAGTAACCCACTTT
TTGCCAACAACTGTCTCAGCATCAAAAGAGGATATTTTGCATATTTTAAAAAGATTCAAAGGTGTCAGGAAATCAATAGG
CGGGCTTCATCTTGAAGGCCCTTTTATAAGTATAGAGAAAAAAGGTGCACAGAATCCCGAACATATCAGAAAACCATCAC
TTGAAGAGCTAAAAGAAATAATAACTGACAGCGTGCGGCTGATCACAATGGCACCGGAAGTGGAAGGTTTTTATGAGGTT
TTACCGTATCTGACTGAACGTGACGTAAGGGTGAGTATTGGCCACTCAAACGCTGTATTTGAAGACATGGCAAAGGCGTT
CCAGAACAATGTTAGGAGAATAACCCATTTCCCTAACGGTTTGAGAGCTCTCCATCACAGGGAATTAGGAGTTGTTGGCG
GAGCGCTATATCTGGATTTTACAATAGAGCTTATTGTGGACGGTGTTCACTCTTCACCGGAATTCGTTGATTTCACGTAT
CGAATAAAAGGGGCAGACAAGATCATACTGATAACAGATTCAATATCTGCCACGGGGTTGAAAGATGGAAGTTACACGCT
GGGTGGTCTTGATGTGAAAGTAGTTGGCGGTAAAGCGACCCTCGCTGATGGAACCCTCGCTGGTAGTACACTCACTTTTG
ACAATGCGGTAAAGAACTTTCACCGTTTTACACACTGTACGCTGAAAGAACTCGCAATGGTTTCTTCTTACAATGCAGCG
CGTGATCTTGGAATAGACGATGAAGGCCGGATTAAAGAGGGGTACAGAGCAAATTTTGTTCTCCTCGATAAAGAGTTGAA
TGTTGTAAAGACGGTCTTTGAAGGGAATGTGGTTTACGAGAAGTGA

Upstream 100 bases:

>100_bases
TGAAGCCGAAAACATTGTTCTATAATTTTTGGAAAAACACACCTGAAAACAAAAGAAATAGAAGTATAATTTAGTAAATG
CTGTTAACAGAGGTGATGAT

Downstream 100 bases:

>100_bases
GATCCGGGAAAAACATGACGCTCGCGAGGCTGTCAGCTGATGGAGCGACATTTGTGAAAGCTGTGCGCTGCTATGCAGCG
GCTGTGCTGAGCTTCGCTCA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLIERVLIVDPVDGEYTGSVQFGEKIERIMKKETDYDYILMPGFIDPHTHGLVGIDTMEASKAAYEKWINENFSRGVTHF
LPTTVSASKEDILHILKRFKGVRKSIGGLHLEGPFISIEKKGAQNPEHIRKPSLEELKEIITDSVRLITMAPEVEGFYEV
LPYLTERDVRVSIGHSNAVFEDMAKAFQNNVRRITHFPNGLRALHHRELGVVGGALYLDFTIELIVDGVHSSPEFVDFTY
RIKGADKIILITDSISATGLKDGSYTLGGLDVKVVGGKATLADGTLAGSTLTFDNAVKNFHRFTHCTLKELAMVSSYNAA
RDLGIDDEGRIKEGYRANFVLLDKELNVVKTVFEGNVVYEK

Sequences:

>Translated_361_residues
MLIERVLIVDPVDGEYTGSVQFGEKIERIMKKETDYDYILMPGFIDPHTHGLVGIDTMEASKAAYEKWINENFSRGVTHF
LPTTVSASKEDILHILKRFKGVRKSIGGLHLEGPFISIEKKGAQNPEHIRKPSLEELKEIITDSVRLITMAPEVEGFYEV
LPYLTERDVRVSIGHSNAVFEDMAKAFQNNVRRITHFPNGLRALHHRELGVVGGALYLDFTIELIVDGVHSSPEFVDFTY
RIKGADKIILITDSISATGLKDGSYTLGGLDVKVVGGKATLADGTLAGSTLTFDNAVKNFHRFTHCTLKELAMVSSYNAA
RDLGIDDEGRIKEGYRANFVLLDKELNVVKTVFEGNVVYEK
>Mature_361_residues
MLIERVLIVDPVDGEYTGSVQFGEKIERIMKKETDYDYILMPGFIDPHTHGLVGIDTMEASKAAYEKWINENFSRGVTHF
LPTTVSASKEDILHILKRFKGVRKSIGGLHLEGPFISIEKKGAQNPEHIRKPSLEELKEIITDSVRLITMAPEVEGFYEV
LPYLTERDVRVSIGHSNAVFEDMAKAFQNNVRRITHFPNGLRALHHRELGVVGGALYLDFTIELIVDGVHSSPEFVDFTY
RIKGADKIILITDSISATGLKDGSYTLGGLDVKVVGGKATLADGTLAGSTLTFDNAVKNFHRFTHCTLKELAMVSSYNAA
RDLGIDDEGRIKEGYRANFVLLDKELNVVKTVFEGNVVYEK

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=374, Percent_Identity=31.0160427807487, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI224922791, Length=372, Percent_Identity=31.1827956989247, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1786892, Length=336, Percent_Identity=30.952380952381, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553768, Length=348, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=7e-39,
Organism=Drosophila melanogaster, GI19920392, Length=343, Percent_Identity=35.5685131195335, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281361140, Length=357, Percent_Identity=34.453781512605, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40234; Mature: 40234

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIERVLIVDPVDGEYTGSVQFGEKIERIMKKETDYDYILMPGFIDPHTHGLVGIDTMEA
CCEEEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECHHH
SKAAYEKWINENFSRGVTHFLPTTVSASKEDILHILKRFKGVRKSIGGLHLEGPFISIEK
HHHHHHHHHHCCHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEC
KGAQNPEHIRKPSLEELKEIITDSVRLITMAPEVEGFYEVLPYLTERDVRVSIGHSNAVF
CCCCCHHHHCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHH
EDMAKAFQNNVRRITHFPNGLRALHHRELGVVGGALYLDFTIELIVDGVHSSPEFVDFTY
HHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCEEEEEE
RIKGADKIILITDSISATGLKDGSYTLGGLDVKVVGGKATLADGTLAGSTLTFDNAVKNF
EECCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCEEEECCCCCCCCEEEHHHHHHHH
HRFTHCTLKELAMVSSYNAARDLGIDDEGRIKEGYRANFVLLDKELNVVKTVFEGNVVYE
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEC
K
C
>Mature Secondary Structure
MLIERVLIVDPVDGEYTGSVQFGEKIERIMKKETDYDYILMPGFIDPHTHGLVGIDTMEA
CCEEEEEEEECCCCCEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCEEEEECHHH
SKAAYEKWINENFSRGVTHFLPTTVSASKEDILHILKRFKGVRKSIGGLHLEGPFISIEK
HHHHHHHHHHCCHHCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEC
KGAQNPEHIRKPSLEELKEIITDSVRLITMAPEVEGFYEVLPYLTERDVRVSIGHSNAVF
CCCCCHHHHCCCCHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHH
EDMAKAFQNNVRRITHFPNGLRALHHRELGVVGGALYLDFTIELIVDGVHSSPEFVDFTY
HHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEEECCCCCCCEEEEEE
RIKGADKIILITDSISATGLKDGSYTLGGLDVKVVGGKATLADGTLAGSTLTFDNAVKNF
EECCCCEEEEEECCCCCCCCCCCCEEECCEEEEEECCEEEECCCCCCCCEEEHHHHHHHH
HRFTHCTLKELAMVSSYNAARDLGIDDEGRIKEGYRANFVLLDKELNVVKTVFEGNVVYE
HHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCCCEEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA