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The map label for this gene is moaC [H]

Identifier: 239617101

GI number: 239617101

Start: 757819

End: 758304

Strand: Direct

Name: moaC [H]

Synonym: Kole_0703

Alternate gene names: 239617101

Gene position: 757819-758304 (Clockwise)

Preceding gene: 239617100

Following gene: 239617102

Centisome position: 32.92

GC content: 45.68

Gene sequence:

>486_bases
ATGAAACTAAGTCACATGGACGACAAGGGCAATGCAAAGATGGTGGATGTCTCTGCCAAAGAAAATACAAAAAGAACAGC
CAAAGCTTATGGAAGAATAGAAATGAGGCCAGAAACCCTCGAGCTGATCGTAAAAAATGGGCTTCCCAAAGGAGACGTAT
TCTCAACCGCCAGAATAGCCGGGATAATGGCTGCGAAAAAGACCTGGGAGCTGATTCCCATGTGCCACAATATTTCTCTG
ACTCATGTGTCTGTCGAGTTCAAAATTGACAGAGACCGTTCTGCTGTTGAAATCTTCACAACGGCGAGTTCCGTTGGAAA
GACCGGAGTCGAAATGGAGGCGTTAACAGCAGCTTCTGTCGCTGCATTGACTATTTATGACATGGCCAAAGCGGTTGACA
AAGAAATGGTCATAGCAGATATCTACTTATTGATGAAAAGCGGCGGCAAAAGCGGGGATTGGAAGAGAGGGAGCGATGAA
AAGTGA

Upstream 100 bases:

>100_bases
TTAAGAAAAATATTTATAATGCTATTAGCTTAAAACCTTTAAGACACGAACTGCTCAACAGAACTCAGAGCAATGGCATG
AACCGGATGGGAGGATAACT

Downstream 100 bases:

>100_bases
AAATCAGATACTTTATCCTTGTTTTGAGTGATAAAGCATATAAAGGTTTGAGGAAAGACGAATGTATCGAAGCTGTGAAG
AGTGTTATTAATAATGCGAG

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MKLSHMDDKGNAKMVDVSAKENTKRTAKAYGRIEMRPETLELIVKNGLPKGDVFSTARIAGIMAAKKTWELIPMCHNISL
THVSVEFKIDRDRSAVEIFTTASSVGKTGVEMEALTAASVAALTIYDMAKAVDKEMVIADIYLLMKSGGKSGDWKRGSDE
K

Sequences:

>Translated_161_residues
MKLSHMDDKGNAKMVDVSAKENTKRTAKAYGRIEMRPETLELIVKNGLPKGDVFSTARIAGIMAAKKTWELIPMCHNISL
THVSVEFKIDRDRSAVEIFTTASSVGKTGVEMEALTAASVAALTIYDMAKAVDKEMVIADIYLLMKSGGKSGDWKRGSDE
K
>Mature_161_residues
MKLSHMDDKGNAKMVDVSAKENTKRTAKAYGRIEMRPETLELIVKNGLPKGDVFSTARIAGIMAAKKTWELIPMCHNISL
THVSVEFKIDRDRSAVEIFTTASSVGKTGVEMEALTAASVAALTIYDMAKAVDKEMVIADIYLLMKSGGKSGDWKRGSDE
K

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=159, Percent_Identity=57.2327044025157, Blast_Score=177, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI32566331, Length=149, Percent_Identity=48.3221476510067, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=50.3225806451613, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI28574492, Length=143, Percent_Identity=51.0489510489511, Blast_Score=144, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17613; Mature: 17613

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSHMDDKGNAKMVDVSAKENTKRTAKAYGRIEMRPETLELIVKNGLPKGDVFSTARIA
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHCEEEECHHHHHHHHHCCCCCCCCHHHHHHH
GIMAAKKTWELIPMCHNISLTHVSVEFKIDRDRSAVEIFTTASSVGKTGVEMEALTAASV
HHHHHCCCHHEEEHCCCCEEEEEEEEEEECCCCCEEEEEEEHHHCCCCCCCHHHHHHHHH
AALTIYDMAKAVDKEMVIADIYLLMKSGGKSGDWKRGSDEK
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLSHMDDKGNAKMVDVSAKENTKRTAKAYGRIEMRPETLELIVKNGLPKGDVFSTARIA
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHCEEEECHHHHHHHHHCCCCCCCCHHHHHHH
GIMAAKKTWELIPMCHNISLTHVSVEFKIDRDRSAVEIFTTASSVGKTGVEMEALTAASV
HHHHHCCCHHEEEHCCCCEEEEEEEEEEECCCCCEEEEEEEHHHCCCCCCCHHHHHHHHH
AALTIYDMAKAVDKEMVIADIYLLMKSGGKSGDWKRGSDEK
HHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA