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The map label for this gene is aes [C]

Identifier: 239617048

GI number: 239617048

Start: 691960

End: 692949

Strand: Direct

Name: aes [C]

Synonym: Kole_0649

Alternate gene names: 239617048

Gene position: 691960-692949 (Clockwise)

Preceding gene: 239617047

Following gene: 239617049

Centisome position: 30.06

GC content: 42.93

Gene sequence:

>990_bases
ATGATAAAACAAATCAACACGGCAAAAATCAAAAGGATAATTAAAGTGATCGTTGCTTTTTCTCTGGTAATGATAGGCTT
CGCATGGAACTGGGCAGTTGTTTTCTTTGCCCTTCTCGTTCTGAATATAAAAACTTTATATCGTGCCCTGCTGGGGAAAC
TGCCCCTGGACGTTCCGGATGAGTCATTCTTTGGCCCTGAAAGCCACATTTACAAACGCGAAGGTAATGCAAACCTAAAA
CTCGATATCTTCTATCCAAAAGAAGGGCTTACGGTGTCGGAAAATTACCCTGTTGTCTTTTTCGCTCACGGTGGAGGCTG
GATAAGTGGCTCCAGGCGACAGGCTAACAATATCTCGTGGTGCAGGTACCTGGCATCAAAAGGCTTTGCGGTTGTAAACA
TTGACTATCGTTTTGGTTATCTCTCCCAAATAGACGATATTCTCAGAGATTACGCGGACGCTTTGGATTTCATCAGGAAA
CAGGCAGAAGAATTCAAAATCGATTCTTCCAGAATAGCGTTGATGGGACTTTCAGCTGGCGGTCACCTCTCTCTATTTCA
TGCCACCTACAATTCCTATTGGAAAAAAGTTGAAAATATGGAAGGCATTAAATGTGTGGTAGCATGGTACGCACCCTCAG
ACTTGATGGATCTATGGGACGACGACGTGGAATCACTCTTTGCTCGTTTTGCCGTTGCCGCCACACTGAAAGGGCTACCA
ACAAAGAAAAAAGAGAACTACATTCACTACTCTCCCATAAACTGGGTTTCAGAAAGGATGGTCCCCACTTTCCTCGTTCA
CGGCAGTGCTGATAAAGTTGTTCCGGTTAAGTCGTCCATCAAACTCTTCAAAAGACTAATGGAGTTTAACGTTCCATCAG
TCTTGAAGATTTATAATGGAGCGGACCATGCCTTTGAGTTTGAGCTTAAAACACCTAAAACAATACGTTTTATAGAAGAA
ACGGTTGAATTTATACGTTCACACGTTTAG

Upstream 100 bases:

>100_bases
TTTCAAAATGAAATTCAAAGGAGCAAGGTTACCAGAAAAGGAATGTCAGGAACTTATTTCAAAATGGAAGGAACTTTGAA
CGATTAAAGTTGTGGTTCAT

Downstream 100 bases:

>100_bases
CGTTCTAAAAAGGGGAGGATAGCATGAACCCCACCTTTGATTACGAGAAAAGAAAAATAGATTTTTCCAGCGGCTATATA
TTCAAAGGTAAGCACTACAG

Product: peptidase S15

Products: alcohol; a carboxylate [C]

Alternate protein names: Alpha/Beta Hydrolase Fold-3 Domain Protein; Lipase/Esterase; Esterase; Alpha/Beta Hydrolase Domain-Containing Protein; Esterase/Lipase; Esterase/Lipase-Like Protein; Peptidase S9 Prolyl Oligopeptidase; Alpha/Beta Hydrolase; Esterase/Lipase/Thioesterase; Alpha/Beta Hydrolase Fold Protein-3 Domain Protein; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase Fold Domain Protein; Esterase/Lipase-Like; Carboxylesterase; Hydrolase; Esterase LipC; Peptidase S; Para-Nitrobenzyl Esterase; Membrane-Bound Esterase LipM; Pectinesterase; Acetyl Esterase Family; Alpha/Beta Hydrolase Fold Protein; Membrane-Anchored Peptidase; Alpha/Beta Hydrolase Fold Family Protein; Coagulation Factor 5/8 Type Domain Protein; Lipase/Esterase Protein; Dienelactone Hydrolase; Esterase/Lipase/Thioesterase Family Protein; Dipeptidyl Aminopeptidases/Acylaminoacyl-Peptidases-Like; Peptidase; Lipase LipA; Peptidase S9 Prolyl Oligopeptidase Active Site Region; Prolyl Oligopeptidase Family Protein; Esterase LipM; Lipoprotein; Peptidase S9A/B/C Family Catalytic Domain Protein

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MIKQINTAKIKRIIKVIVAFSLVMIGFAWNWAVVFFALLVLNIKTLYRALLGKLPLDVPDESFFGPESHIYKREGNANLK
LDIFYPKEGLTVSENYPVVFFAHGGGWISGSRRQANNISWCRYLASKGFAVVNIDYRFGYLSQIDDILRDYADALDFIRK
QAEEFKIDSSRIALMGLSAGGHLSLFHATYNSYWKKVENMEGIKCVVAWYAPSDLMDLWDDDVESLFARFAVAATLKGLP
TKKKENYIHYSPINWVSERMVPTFLVHGSADKVVPVKSSIKLFKRLMEFNVPSVLKIYNGADHAFEFELKTPKTIRFIEE
TVEFIRSHV

Sequences:

>Translated_329_residues
MIKQINTAKIKRIIKVIVAFSLVMIGFAWNWAVVFFALLVLNIKTLYRALLGKLPLDVPDESFFGPESHIYKREGNANLK
LDIFYPKEGLTVSENYPVVFFAHGGGWISGSRRQANNISWCRYLASKGFAVVNIDYRFGYLSQIDDILRDYADALDFIRK
QAEEFKIDSSRIALMGLSAGGHLSLFHATYNSYWKKVENMEGIKCVVAWYAPSDLMDLWDDDVESLFARFAVAATLKGLP
TKKKENYIHYSPINWVSERMVPTFLVHGSADKVVPVKSSIKLFKRLMEFNVPSVLKIYNGADHAFEFELKTPKTIRFIEE
TVEFIRSHV
>Mature_329_residues
MIKQINTAKIKRIIKVIVAFSLVMIGFAWNWAVVFFALLVLNIKTLYRALLGKLPLDVPDESFFGPESHIYKREGNANLK
LDIFYPKEGLTVSENYPVVFFAHGGGWISGSRRQANNISWCRYLASKGFAVVNIDYRFGYLSQIDDILRDYADALDFIRK
QAEEFKIDSSRIALMGLSAGGHLSLFHATYNSYWKKVENMEGIKCVVAWYAPSDLMDLWDDDVESLFARFAVAATLKGLP
TKKKENYIHYSPINWVSERMVPTFLVHGSADKVVPVKSSIKLFKRLMEFNVPSVLKIYNGADHAFEFELKTPKTIRFIEE
TVEFIRSHV

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17552908, Length=254, Percent_Identity=26.7716535433071, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556436, Length=113, Percent_Identity=37.1681415929204, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 37647; Mature: 37647

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQINTAKIKRIIKVIVAFSLVMIGFAWNWAVVFFALLVLNIKTLYRALLGKLPLDVPD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ESFFGPESHIYKREGNANLKLDIFYPKEGLTVSENYPVVFFAHGGGWISGSRRQANNISW
CCCCCCCHHEEEECCCCEEEEEEEECCCCCEEECCCCEEEEECCCCEECCCCCCCCCHHH
CRYLASKGFAVVNIDYRFGYLSQIDDILRDYADALDFIRKQAEEFKIDSSRIALMGLSAG
HHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GHLSLFHATYNSYWKKVENMEGIKCVVAWYAPSDLMDLWDDDVESLFARFAVAATLKGLP
CCEEEEHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TKKKENYIHYSPINWVSERMVPTFLVHGSADKVVPVKSSIKLFKRLMEFNVPSVLKIYNG
CCCCCCEEEECCHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHCCCCHHHHHHCC
ADHAFEFELKTPKTIRFIEETVEFIRSHV
CCCEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIKQINTAKIKRIIKVIVAFSLVMIGFAWNWAVVFFALLVLNIKTLYRALLGKLPLDVPD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ESFFGPESHIYKREGNANLKLDIFYPKEGLTVSENYPVVFFAHGGGWISGSRRQANNISW
CCCCCCCHHEEEECCCCEEEEEEEECCCCCEEECCCCEEEEECCCCEECCCCCCCCCHHH
CRYLASKGFAVVNIDYRFGYLSQIDDILRDYADALDFIRKQAEEFKIDSSRIALMGLSAG
HHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
GHLSLFHATYNSYWKKVENMEGIKCVVAWYAPSDLMDLWDDDVESLFARFAVAATLKGLP
CCEEEEHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TKKKENYIHYSPINWVSERMVPTFLVHGSADKVVPVKSSIKLFKRLMEFNVPSVLKIYNG
CCCCCCEEEECCHHHHHHHCCCEEEEECCCCCEEECHHHHHHHHHHHHCCCCHHHHHHCC
ADHAFEFELKTPKTIRFIEETVEFIRSHV
CCCEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA