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The map label for this gene is ppnK [H]

Identifier: 239616613

GI number: 239616613

Start: 234481

End: 235305

Strand: Reverse

Name: ppnK [H]

Synonym: Kole_0206

Alternate gene names: 239616613

Gene position: 235305-234481 (Counterclockwise)

Preceding gene: 239616614

Following gene: 239616612

Centisome position: 10.22

GC content: 45.58

Gene sequence:

>825_bases
TTGAAAGCCATTGTGTTTTTCAACCACAAACGACTCGATGAAGAGATGATTCAGAAGATAATTTCCTTTCTGGGATCTTT
CAACATAGATGTTTTCATCGGTGATACCTTTTCCGGGAAGCAAAATCACGATTACGAACCAGAAGTGATCATGACCTTTG
GTGGCGATGGAACGGTTTTGAGAGCCGTTCCCTTTGCTGTTGAGCGCGATCTCCCGATTTTGAGCTTTAAGGTCGGTAGT
GTTGGCTTTTTAGCGGCTTTTGAGCTCGGAGAACTGGAAACTGCCATAGGAAAGTTTGTTGACAATAGGCTTCATATGGA
AGAGCGCTATCTCCTTGAGGTGAGTTTTAAAGAGAAACGTTATAAGGTTCTCAATGATTGTGCCGTGGAAAGGGGCGATC
CGAGCCGTACAACCTCTTTAGAGGTAGAAATCGAAGGTTTTTCAGCTTACAGGATCGTCGGTGATGGCGTGATTCTGTCC
ACGGGTACTGGTTCAACGGCTTACAACCTTTCTATTGGCGGTGCTCTGGTAGATCCGATGGCAAAGGTTTATCAGGTAAC
ACCCGTTGCCCCTCACAACCCCTTTGTCGGGTCGATAATAGTGGATTCCACAAGAAAAACAAAGGTTACCGTGATTGACG
GAAAGAATGCCCCGATGAAACTCTACCTTGATGGAATACTGACAGCCGTGCTGCGGGACGGCGATGAAATCGTTGCGGGA
ATTTCCGATAAAAAAGTGAAACTCTTAAGGGATGCCGGTTTTGATTTTGTACGTGTATTGAAGAGAAAGCTTGCCTTTGG
CGGGAGGCTTAAAGATGATCTCTAA

Upstream 100 bases:

>100_bases
TGCCATACTCGTGCTGGTTTTTATAGATCAGTTCCTGGTGGGTTCTCTCTTTGACCTGTCGTATGTTATCCGTGCTGCTT
CCGGTTTGTGAGGTGATCAA

Downstream 100 bases:

>100_bases
AAAAGGGCTGAGAAAGATCGAGGAAACCAAGCATGAAATAATAAATATGGCGCGTTACGTCCAGAACCTCTTTTCTAAAT
GTTCTCTGGCTATTTTAAGC

Product: ATP-NAD/AcoX kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKAIVFFNHKRLDEEMIQKIISFLGSFNIDVFIGDTFSGKQNHDYEPEVIMTFGGDGTVLRAVPFAVERDLPILSFKVGS
VGFLAAFELGELETAIGKFVDNRLHMEERYLLEVSFKEKRYKVLNDCAVERGDPSRTTSLEVEIEGFSAYRIVGDGVILS
TGTGSTAYNLSIGGALVDPMAKVYQVTPVAPHNPFVGSIIVDSTRKTKVTVIDGKNAPMKLYLDGILTAVLRDGDEIVAG
ISDKKVKLLRDAGFDFVRVLKRKLAFGGRLKDDL

Sequences:

>Translated_274_residues
MKAIVFFNHKRLDEEMIQKIISFLGSFNIDVFIGDTFSGKQNHDYEPEVIMTFGGDGTVLRAVPFAVERDLPILSFKVGS
VGFLAAFELGELETAIGKFVDNRLHMEERYLLEVSFKEKRYKVLNDCAVERGDPSRTTSLEVEIEGFSAYRIVGDGVILS
TGTGSTAYNLSIGGALVDPMAKVYQVTPVAPHNPFVGSIIVDSTRKTKVTVIDGKNAPMKLYLDGILTAVLRDGDEIVAG
ISDKKVKLLRDAGFDFVRVLKRKLAFGGRLKDDL
>Mature_274_residues
MKAIVFFNHKRLDEEMIQKIISFLGSFNIDVFIGDTFSGKQNHDYEPEVIMTFGGDGTVLRAVPFAVERDLPILSFKVGS
VGFLAAFELGELETAIGKFVDNRLHMEERYLLEVSFKEKRYKVLNDCAVERGDPSRTTSLEVEIEGFSAYRIVGDGVILS
TGTGSTAYNLSIGGALVDPMAKVYQVTPVAPHNPFVGSIIVDSTRKTKVTVIDGKNAPMKLYLDGILTAVLRDGDEIVAG
ISDKKVKLLRDAGFDFVRVLKRKLAFGGRLKDDL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=256, Percent_Identity=25.390625, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788968, Length=222, Percent_Identity=22.972972972973, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325068, Length=202, Percent_Identity=32.6732673267327, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6320794, Length=251, Percent_Identity=28.2868525896414, Blast_Score=102, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322509, Length=249, Percent_Identity=27.710843373494, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30219; Mature: 30219

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVFFNHKRLDEEMIQKIISFLGSFNIDVFIGDTFSGKQNHDYEPEVIMTFGGDGTVL
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEE
RAVPFAVERDLPILSFKVGSVGFLAAFELGELETAIGKFVDNRLHMEERYLLEVSFKEKR
EEECHHHCCCCCEEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHH
YKVLNDCAVERGDPSRTTSLEVEIEGFSAYRIVGDGVILSTGTGSTAYNLSIGGALVDPM
HHHHHHHHCCCCCCCCCEEEEEEEECCEEEEEEECCEEEECCCCCEEEEEEECCHHHHHH
AKVYQVTPVAPHNPFVGSIIVDSTRKTKVTVIDGKNAPMKLYLDGILTAVLRDGDEIVAG
HHHEEECCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCCCEEEC
ISDKKVKLLRDAGFDFVRVLKRKLAFGGRLKDDL
CCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKAIVFFNHKRLDEEMIQKIISFLGSFNIDVFIGDTFSGKQNHDYEPEVIMTFGGDGTVL
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCEE
RAVPFAVERDLPILSFKVGSVGFLAAFELGELETAIGKFVDNRLHMEERYLLEVSFKEKR
EEECHHHCCCCCEEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEECHHH
YKVLNDCAVERGDPSRTTSLEVEIEGFSAYRIVGDGVILSTGTGSTAYNLSIGGALVDPM
HHHHHHHHCCCCCCCCCEEEEEEEECCEEEEEEECCEEEECCCCCEEEEEEECCHHHHHH
AKVYQVTPVAPHNPFVGSIIVDSTRKTKVTVIDGKNAPMKLYLDGILTAVLRDGDEIVAG
HHHEEECCCCCCCCCEEEEEEECCCCEEEEEEECCCCCEEEEHHHHHHHHHCCCCCEEEC
ISDKKVKLLRDAGFDFVRVLKRKLAFGGRLKDDL
CCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA