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The map label for this gene is smc [H]

Identifier: 239616597

GI number: 239616597

Start: 210837

End: 214358

Strand: Reverse

Name: smc [H]

Synonym: Kole_0189

Alternate gene names: 239616597

Gene position: 214358-210837 (Counterclockwise)

Preceding gene: 239616598

Following gene: 239616596

Centisome position: 9.31

GC content: 45.2

Gene sequence:

>3522_bases
ATGAGACTCGTTTCTATATTCATAAAAGGTTTTAAGAGTTTCGCTTATCCGACAAAGATAGATATAAGTAAAGGTATAAC
GGCCATAGTGGGTCCAAACGGCAGCGGGAAGTCAAACATCGTGGATGCCATCCGCTGGGTTTTTGGTGAACAGTCAATGA
AAACCATAAGGGCGGACAATCGTGAAGACGTAATCTTCGCCGGTTCCGAAAAGAATCCGCCTGCCAATTCGGCTGTTGTC
AAACTCACCTTTGAGGATGAACGCGGTTTGATTACTATCGGCCGTGAGATAACGAGAGATGGATTGTCTCAATACAGTAT
AAATGACAAGCCATCGCGACTGAGGGATATAAAAGAGATCTTTCAGGGTACCGGTGTCGGTATGGATATATATTCAATAG
TGGGCCAGGGACAGGTGGACAAGGTCGTTACCGCTTCCCCATATGAATTGAGGGCTTTGATTGAAGAAGCAGCGGGAACC
GCGATTTACAAGGAAAAGAAGAAACAGTCTCTCGCCAAGCTATCGGAAACTGAAGCGAATCTAAACCGTATAGAGGACAT
TCTCTTTGAACTTGGAAAGCAGAGAAAGTCTCTGTACCTCAAGGCGAAGAGAGCAGAAAAATACCTTGAATATACCGAAA
GACTCAAGGAGGTAAGGACCCTTTATTATGGTAACGCCGTGCGAGTAGAAAGGGAGATCCTGAACACGCACATGGAGGGG
CACGAAAAGGTAAGCGACGAACTCAAGGAATTGCAGAGAAAGCTCATAGAGCATGAATCAAAATGGTCAACCCTGAGACA
GGAATTCTCCGAGATGGACAAAGAAATAGAGGGTTTTACCCGGTTGCTCGAAGAGTACAAGAAAAGGCAAAACGATCTAC
TTGAGTTGAAGGAGATGTACTCAAAGAAACTTAGCGATAAGGAAAGTAAGCTAATAGAGGTTAGCACGAAATTAGACACG
TTGAAGGCAGAGGTTGAAGACCTTGAGAAGAGGAAAGATGAGTTAAAACTCATAAGTGATGGGATGAAACAGCAGATTGA
AGACGAAGAAAAGGAATTGAAAGAGCTTGAGAGTATTAAAGATTCCATGGTACATAAGTACAGCGAAAAGGAGAAAGACT
GGCTGAAACTGCAGGAAGAACTCGATTCCGTAGTGAAGAGGATGTCTAAGATAGAGAACGAGCTGGAGAGGCTCAGTAAT
GTTAGAGAAGACACCCAGAAGAGGTTGAATCTTATAGGTTCTCAACTTCAATCCAAGGGAGAGCGTCTTGAAGACCTGAA
AAAAGAGATAGAGGAGCTGGCGGCTCAGGGAAAAGAGAGTACGGAGAAACAAAAAGAGCTGGAGGAAAACATAGCACTCT
CAAAGGAAAGAAGAGACACTCTCGAGAATCAACTCGAGGAACTCAAAGAAAAGATAGCCCAATCCATGGAGGAGCTTCGA
CGTTCCCAGATTGAAAGAAATACCCTGGAGAGACAGCAACTGGAGTATCAGGGTTTTTCAAGAGCGGTTCGAGAAATTTT
CTCGAGGAGCGACGATTTTGATGGGCTCATCGATGTTGTTGCCAACCTTGTCGAAATTCCCAAAACCTTTGAGACGGCTG
TCAGTGTCCTTCTGGGTTCCAGAATGCAGGATGTTGTGGTTGAGAGCTCAATAACCGCGAAAAGAATTGTTGCCTTTTTG
AAGCAGCATAAAATCGGAAGGTTAACGCTTTTACCTCTGGATATGCTGAAGGGTAATTTCAAGAGATTCAAAGCGGTTGA
AAATCATCCGGGATTTCTCGGTTATGCTGCTAAAGTTGTTGATGTTGCAGAGGAGTTCAAAATCGTTCCCGAGTATCTCT
TTGGTAGCGCTATTGTGGTGAAATCTCTGGATGACGCTATAGATATTCGTAAGAACCTAGGGTTCCAGGGGAGGATAGTG
TCTTTGGACGGACAGCTTCTTTCGGCCGGTGGAGCGATAACCGGTGGATACATCGGAAACGATGTCAGGCTGGACCTCGT
TACCAGAAAGCGCAGAATTCAGGAGCTTGAACAGAAAGAGAAAGATCTGCAAAAAGCTATGGAACGAATGCAACGTGAAT
CGGTTAAGATCAAGGACGAGATTCAGGAACTCAGGGGATATATCAGGGTTCTCAATGAGGAATTGAACGGGATCATTTCA
AAGGGTGCAGCCATCAACAGGATGATTCACGAACTTTTGAAGACGGCTAATGAGCTTGAAAGCGAAATTAGCGAACTCGA
TAAGCTGAAGGAAGAGTACACGAAGAAACTGAACGATAGCCTGAATAAGAGGGAAGAACTGGAAGAGGAATTTAAGACCC
TCAACCAGCAGAAAAAGGAATTCGAGAAAGAGCTTCAAACCTTCTCTCAGGAACTGAAAGAAGAAAAGAAGAAACTTGAG
GAGATCCAGAACCAGATAGTTGACAGGAAGTTGAAACTTTCAGGATTGTACGAAAAGCAGGAACAGTACACGAAAGAGCT
ATCTGCTATAAGCCAGAAGAAACGCGAGAACTCCGAAGCGATAATTGTACTCGAGAGAGAGATCGAAGAGCTGGAGAATG
AAGCGGAAAAGCTCAGGAAGCAGGTTGCCGATCAGGATAGGGAGCTCCAATCGGTCAAGCGGGAAACCGAAGCGCTCTTT
TCGAGCATCAGGGATCAAAGGCAGGGAAAGGAAGAACGTCTCAATGCCCTGCAGGAGCTTGAGAGTGAGATCGAAGCCCT
CAAGAGTGAGAGAGAACAGAAGAGAGAGAAGCTTCATCAGTTTGACCTTTTAATCCAGGAATCGAAGATGCGGCTAGAGC
AGCTGGAAAAAGAACTTGGAGAGGTTGAAGGCGAGATACCGGTGCTGAGCGATGAAGAGCTGGAAAAGACCCGGATGGAA
CTTGAGGAGCTGGAAAACAAGCTTAAATTCCTCGGTAGTGTTGACCTCGATGCCATCGAAGAATACAAGCTGGTTGACGC
TGAGTATCAGGAATTGATGGTTCAAAAGGAAGATCTGGAAGAGGCACGCCAGAAGCTAATTAAACTGATAGAAAAGATCG
ACGAAGAAGCGAGAAATCGTTTCAAAAGCACATATGAAAAGGTTAACGAGAATTTTGGAAAATATATATCGGAGATTTTT
GACGGCGGTGAAGGCGAGATCCGTATAATCCCGGGCGAGGATTTGCTGGAATCAGGGCTTGAGATCTCTGTCAGACGGCC
AGGTAGAAAATTCCAGAAGCTTCAGCTCTTTTCCGGTGGGGAAAAGGCCCTGGTAGGAATAGCCCTGGTGTTCGCGCTTT
TGAGCATCAAACCCAGTCCTTTCTATGTTCTGGATGAGGTGGATGCCCCGCTAGATGATTTCAACGCCGAGCGATTCAAG
AATATGCTGAGAAGGCATGGCGAGGACACGCAGTTTCTTGTAATAACCCACAACAAGATTGTGATGGAAGTTGCGTATGT
TCTTCATGGTATCACGATGACAGACGGAATTTCCAGAGTTATACCCGTTAAACTCGGGACCATCGAGTCCGTTATAGGTT
GA

Upstream 100 bases:

>100_bases
ATCTAAGAGAACTCATGAAAATTGTGTTGGTTGAGTCTTTAGATGAGCTCTTTCGCTCTGAAGTTTCCGGGATATTGCTG
GCGAATTAGGGGGTACAGTC

Downstream 100 bases:

>100_bases
TTTTTTAGAGGTGATGGCCACGGAGCTTGGAGTTGTAACCACGGAGATAGGTGCTATTCTTTTGCATGCTGATTATGGAA
TGCTTTCGAGGATAGAGCTT

Product: chromosome segregation protein SMC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1173; Mature: 1173

Protein sequence:

>1173_residues
MRLVSIFIKGFKSFAYPTKIDISKGITAIVGPNGSGKSNIVDAIRWVFGEQSMKTIRADNREDVIFAGSEKNPPANSAVV
KLTFEDERGLITIGREITRDGLSQYSINDKPSRLRDIKEIFQGTGVGMDIYSIVGQGQVDKVVTASPYELRALIEEAAGT
AIYKEKKKQSLAKLSETEANLNRIEDILFELGKQRKSLYLKAKRAEKYLEYTERLKEVRTLYYGNAVRVEREILNTHMEG
HEKVSDELKELQRKLIEHESKWSTLRQEFSEMDKEIEGFTRLLEEYKKRQNDLLELKEMYSKKLSDKESKLIEVSTKLDT
LKAEVEDLEKRKDELKLISDGMKQQIEDEEKELKELESIKDSMVHKYSEKEKDWLKLQEELDSVVKRMSKIENELERLSN
VREDTQKRLNLIGSQLQSKGERLEDLKKEIEELAAQGKESTEKQKELEENIALSKERRDTLENQLEELKEKIAQSMEELR
RSQIERNTLERQQLEYQGFSRAVREIFSRSDDFDGLIDVVANLVEIPKTFETAVSVLLGSRMQDVVVESSITAKRIVAFL
KQHKIGRLTLLPLDMLKGNFKRFKAVENHPGFLGYAAKVVDVAEEFKIVPEYLFGSAIVVKSLDDAIDIRKNLGFQGRIV
SLDGQLLSAGGAITGGYIGNDVRLDLVTRKRRIQELEQKEKDLQKAMERMQRESVKIKDEIQELRGYIRVLNEELNGIIS
KGAAINRMIHELLKTANELESEISELDKLKEEYTKKLNDSLNKREELEEEFKTLNQQKKEFEKELQTFSQELKEEKKKLE
EIQNQIVDRKLKLSGLYEKQEQYTKELSAISQKKRENSEAIIVLEREIEELENEAEKLRKQVADQDRELQSVKRETEALF
SSIRDQRQGKEERLNALQELESEIEALKSEREQKREKLHQFDLLIQESKMRLEQLEKELGEVEGEIPVLSDEELEKTRME
LEELENKLKFLGSVDLDAIEEYKLVDAEYQELMVQKEDLEEARQKLIKLIEKIDEEARNRFKSTYEKVNENFGKYISEIF
DGGEGEIRIIPGEDLLESGLEISVRRPGRKFQKLQLFSGGEKALVGIALVFALLSIKPSPFYVLDEVDAPLDDFNAERFK
NMLRRHGEDTQFLVITHNKIVMEVAYVLHGITMTDGISRVIPVKLGTIESVIG

Sequences:

>Translated_1173_residues
MRLVSIFIKGFKSFAYPTKIDISKGITAIVGPNGSGKSNIVDAIRWVFGEQSMKTIRADNREDVIFAGSEKNPPANSAVV
KLTFEDERGLITIGREITRDGLSQYSINDKPSRLRDIKEIFQGTGVGMDIYSIVGQGQVDKVVTASPYELRALIEEAAGT
AIYKEKKKQSLAKLSETEANLNRIEDILFELGKQRKSLYLKAKRAEKYLEYTERLKEVRTLYYGNAVRVEREILNTHMEG
HEKVSDELKELQRKLIEHESKWSTLRQEFSEMDKEIEGFTRLLEEYKKRQNDLLELKEMYSKKLSDKESKLIEVSTKLDT
LKAEVEDLEKRKDELKLISDGMKQQIEDEEKELKELESIKDSMVHKYSEKEKDWLKLQEELDSVVKRMSKIENELERLSN
VREDTQKRLNLIGSQLQSKGERLEDLKKEIEELAAQGKESTEKQKELEENIALSKERRDTLENQLEELKEKIAQSMEELR
RSQIERNTLERQQLEYQGFSRAVREIFSRSDDFDGLIDVVANLVEIPKTFETAVSVLLGSRMQDVVVESSITAKRIVAFL
KQHKIGRLTLLPLDMLKGNFKRFKAVENHPGFLGYAAKVVDVAEEFKIVPEYLFGSAIVVKSLDDAIDIRKNLGFQGRIV
SLDGQLLSAGGAITGGYIGNDVRLDLVTRKRRIQELEQKEKDLQKAMERMQRESVKIKDEIQELRGYIRVLNEELNGIIS
KGAAINRMIHELLKTANELESEISELDKLKEEYTKKLNDSLNKREELEEEFKTLNQQKKEFEKELQTFSQELKEEKKKLE
EIQNQIVDRKLKLSGLYEKQEQYTKELSAISQKKRENSEAIIVLEREIEELENEAEKLRKQVADQDRELQSVKRETEALF
SSIRDQRQGKEERLNALQELESEIEALKSEREQKREKLHQFDLLIQESKMRLEQLEKELGEVEGEIPVLSDEELEKTRME
LEELENKLKFLGSVDLDAIEEYKLVDAEYQELMVQKEDLEEARQKLIKLIEKIDEEARNRFKSTYEKVNENFGKYISEIF
DGGEGEIRIIPGEDLLESGLEISVRRPGRKFQKLQLFSGGEKALVGIALVFALLSIKPSPFYVLDEVDAPLDDFNAERFK
NMLRRHGEDTQFLVITHNKIVMEVAYVLHGITMTDGISRVIPVKLGTIESVIG
>Mature_1173_residues
MRLVSIFIKGFKSFAYPTKIDISKGITAIVGPNGSGKSNIVDAIRWVFGEQSMKTIRADNREDVIFAGSEKNPPANSAVV
KLTFEDERGLITIGREITRDGLSQYSINDKPSRLRDIKEIFQGTGVGMDIYSIVGQGQVDKVVTASPYELRALIEEAAGT
AIYKEKKKQSLAKLSETEANLNRIEDILFELGKQRKSLYLKAKRAEKYLEYTERLKEVRTLYYGNAVRVEREILNTHMEG
HEKVSDELKELQRKLIEHESKWSTLRQEFSEMDKEIEGFTRLLEEYKKRQNDLLELKEMYSKKLSDKESKLIEVSTKLDT
LKAEVEDLEKRKDELKLISDGMKQQIEDEEKELKELESIKDSMVHKYSEKEKDWLKLQEELDSVVKRMSKIENELERLSN
VREDTQKRLNLIGSQLQSKGERLEDLKKEIEELAAQGKESTEKQKELEENIALSKERRDTLENQLEELKEKIAQSMEELR
RSQIERNTLERQQLEYQGFSRAVREIFSRSDDFDGLIDVVANLVEIPKTFETAVSVLLGSRMQDVVVESSITAKRIVAFL
KQHKIGRLTLLPLDMLKGNFKRFKAVENHPGFLGYAAKVVDVAEEFKIVPEYLFGSAIVVKSLDDAIDIRKNLGFQGRIV
SLDGQLLSAGGAITGGYIGNDVRLDLVTRKRRIQELEQKEKDLQKAMERMQRESVKIKDEIQELRGYIRVLNEELNGIIS
KGAAINRMIHELLKTANELESEISELDKLKEEYTKKLNDSLNKREELEEEFKTLNQQKKEFEKELQTFSQELKEEKKKLE
EIQNQIVDRKLKLSGLYEKQEQYTKELSAISQKKRENSEAIIVLEREIEELENEAEKLRKQVADQDRELQSVKRETEALF
SSIRDQRQGKEERLNALQELESEIEALKSEREQKREKLHQFDLLIQESKMRLEQLEKELGEVEGEIPVLSDEELEKTRME
LEELENKLKFLGSVDLDAIEEYKLVDAEYQELMVQKEDLEEARQKLIKLIEKIDEEARNRFKSTYEKVNENFGKYISEIF
DGGEGEIRIIPGEDLLESGLEISVRRPGRKFQKLQLFSGGEKALVGIALVFALLSIKPSPFYVLDEVDAPLDDFNAERFK
NMLRRHGEDTQFLVITHNKIVMEVAYVLHGITMTDGISRVIPVKLGTIESVIG

Specific function: Plays an important role in chromosome structure and partitioning. Essential for chromosome partition [H]

COG id: COG1196

COG function: function code D; Chromosome segregation ATPases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family [H]

Homologues:

Organism=Homo sapiens, GI110347425, Length=1247, Percent_Identity=24.4587008821171, Blast_Score=246, Evalue=7e-65,
Organism=Homo sapiens, GI110347420, Length=1247, Percent_Identity=24.4587008821171, Blast_Score=246, Evalue=7e-65,
Organism=Homo sapiens, GI110347418, Length=1247, Percent_Identity=24.4587008821171, Blast_Score=246, Evalue=7e-65,
Organism=Homo sapiens, GI30581135, Length=1293, Percent_Identity=24.2846094354215, Blast_Score=222, Evalue=1e-57,
Organism=Homo sapiens, GI71565160, Length=1234, Percent_Identity=23.9870340356564, Blast_Score=192, Evalue=2e-48,
Organism=Homo sapiens, GI4885399, Length=1309, Percent_Identity=22.3834988540871, Blast_Score=192, Evalue=2e-48,
Organism=Homo sapiens, GI50658065, Length=709, Percent_Identity=24.1184767277856, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI50658063, Length=709, Percent_Identity=24.1184767277856, Blast_Score=140, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17535279, Length=1262, Percent_Identity=24.4849445324881, Blast_Score=187, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17552844, Length=1315, Percent_Identity=23.2699619771863, Blast_Score=157, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI193210872, Length=700, Percent_Identity=25.1428571428571, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI212656546, Length=743, Percent_Identity=23.6877523553163, Blast_Score=133, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17553272, Length=239, Percent_Identity=31.3807531380753, Blast_Score=114, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI193202684, Length=189, Percent_Identity=27.5132275132275, Blast_Score=73, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321104, Length=1272, Percent_Identity=24.9213836477987, Blast_Score=227, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6322387, Length=1320, Percent_Identity=24.6969696969697, Blast_Score=192, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6321144, Length=1252, Percent_Identity=24.3610223642173, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323115, Length=231, Percent_Identity=31.6017316017316, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24642555, Length=1257, Percent_Identity=24.4232299124901, Blast_Score=218, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24649535, Length=1263, Percent_Identity=23.1195566112431, Blast_Score=196, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19922276, Length=1315, Percent_Identity=23.1939163498099, Blast_Score=191, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24642557, Length=1105, Percent_Identity=23.8914027149321, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24584683, Length=137, Percent_Identity=33.5766423357664, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281366584, Length=409, Percent_Identity=25.6723716381418, Blast_Score=69, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281366582, Length=409, Percent_Identity=25.6723716381418, Blast_Score=68, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395
- InterPro:   IPR010935
- InterPro:   IPR011890 [H]

Pfam domain/function: PF06470 SMC_hinge; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 135633; Mature: 135633

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVSIFIKGFKSFAYPTKIDISKGITAIVGPNGSGKSNIVDAIRWVFGEQSMKTIRADN
CHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
REDVIFAGSEKNPPANSAVVKLTFEDERGLITIGREITRDGLSQYSINDKPSRLRDIKEI
CCCEEEECCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FQGTGVGMDIYSIVGQGQVDKVVTASPYELRALIEEAAGTAIYKEKKKQSLAKLSETEAN
HCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LNRIEDILFELGKQRKSLYLKAKRAEKYLEYTERLKEVRTLYYGNAVRVEREILNTHMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HEKVSDELKELQRKLIEHESKWSTLRQEFSEMDKEIEGFTRLLEEYKKRQNDLLELKEMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKLSDKESKLIEVSTKLDTLKAEVEDLEKRKDELKLISDGMKQQIEDEEKELKELESIK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSMVHKYSEKEKDWLKLQEELDSVVKRMSKIENELERLSNVREDTQKRLNLIGSQLQSKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLEDLKKEIEELAAQGKESTEKQKELEENIALSKERRDTLENQLEELKEKIAQSMEELR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQIERNTLERQQLEYQGFSRAVREIFSRSDDFDGLIDVVANLVEIPKTFETAVSVLLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
RMQDVVVESSITAKRIVAFLKQHKIGRLTLLPLDMLKGNFKRFKAVENHPGFLGYAAKVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHCCCCCHHHHHHHHH
DVAEEFKIVPEYLFGSAIVVKSLDDAIDIRKNLGFQGRIVSLDGQLLSAGGAITGGYIGN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCEECCCCCC
DVRLDLVTRKRRIQELEQKEKDLQKAMERMQRESVKIKDEIQELRGYIRVLNEELNGIIS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KGAAINRMIHELLKTANELESEISELDKLKEEYTKKLNDSLNKREELEEEFKTLNQQKKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKELQTFSQELKEEKKKLEEIQNQIVDRKLKLSGLYEKQEQYTKELSAISQKKRENSEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IIVLEREIEELENEAEKLRKQVADQDRELQSVKRETEALFSSIRDQRQGKEERLNALQEL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ESEIEALKSEREQKREKLHQFDLLIQESKMRLEQLEKELGEVEGEIPVLSDEELEKTRME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LEELENKLKFLGSVDLDAIEEYKLVDAEYQELMVQKEDLEEARQKLIKLIEKIDEEARNR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKSTYEKVNENFGKYISEIFDGGEGEIRIIPGEDLLESGLEISVRRPGRKFQKLQLFSGG
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCEEEECCCCHHHHHHHHHCCC
EKALVGIALVFALLSIKPSPFYVLDEVDAPLDDFNAERFKNMLRRHGEDTQFLVITHNKI
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
VMEVAYVLHGITMTDGISRVIPVKLGTIESVIG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLVSIFIKGFKSFAYPTKIDISKGITAIVGPNGSGKSNIVDAIRWVFGEQSMKTIRADN
CHHHHHHHHHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
REDVIFAGSEKNPPANSAVVKLTFEDERGLITIGREITRDGLSQYSINDKPSRLRDIKEI
CCCEEEECCCCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
FQGTGVGMDIYSIVGQGQVDKVVTASPYELRALIEEAAGTAIYKEKKKQSLAKLSETEAN
HCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LNRIEDILFELGKQRKSLYLKAKRAEKYLEYTERLKEVRTLYYGNAVRVEREILNTHMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HEKVSDELKELQRKLIEHESKWSTLRQEFSEMDKEIEGFTRLLEEYKKRQNDLLELKEMY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKKLSDKESKLIEVSTKLDTLKAEVEDLEKRKDELKLISDGMKQQIEDEEKELKELESIK
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DSMVHKYSEKEKDWLKLQEELDSVVKRMSKIENELERLSNVREDTQKRLNLIGSQLQSKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERLEDLKKEIEELAAQGKESTEKQKELEENIALSKERRDTLENQLEELKEKIAQSMEELR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSQIERNTLERQQLEYQGFSRAVREIFSRSDDFDGLIDVVANLVEIPKTFETAVSVLLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
RMQDVVVESSITAKRIVAFLKQHKIGRLTLLPLDMLKGNFKRFKAVENHPGFLGYAAKVV
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCHHHHHHHCCCCCHHHHHHHHH
DVAEEFKIVPEYLFGSAIVVKSLDDAIDIRKNLGFQGRIVSLDGQLLSAGGAITGGYIGN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCEECCCCCC
DVRLDLVTRKRRIQELEQKEKDLQKAMERMQRESVKIKDEIQELRGYIRVLNEELNGIIS
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
KGAAINRMIHELLKTANELESEISELDKLKEEYTKKLNDSLNKREELEEEFKTLNQQKKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEKELQTFSQELKEEKKKLEEIQNQIVDRKLKLSGLYEKQEQYTKELSAISQKKRENSEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
IIVLEREIEELENEAEKLRKQVADQDRELQSVKRETEALFSSIRDQRQGKEERLNALQEL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
ESEIEALKSEREQKREKLHQFDLLIQESKMRLEQLEKELGEVEGEIPVLSDEELEKTRME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
LEELENKLKFLGSVDLDAIEEYKLVDAEYQELMVQKEDLEEARQKLIKLIEKIDEEARNR
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKSTYEKVNENFGKYISEIFDGGEGEIRIIPGEDLLESGLEISVRRPGRKFQKLQLFSGG
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCEEEECCCCHHHHHHHHHCCC
EKALVGIALVFALLSIKPSPFYVLDEVDAPLDDFNAERFKNMLRRHGEDTQFLVITHNKI
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCHH
VMEVAYVLHGITMTDGISRVIPVKLGTIESVIG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654983; 9384377; 7584053; 9701812; 9573042 [H]