Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 239616558

GI number: 239616558

Start: 167595

End: 168053

Strand: Reverse

Name: fur [H]

Synonym: Kole_0150

Alternate gene names: 239616558

Gene position: 168053-167595 (Counterclockwise)

Preceding gene: 239616559

Following gene: 239616557

Centisome position: 7.3

GC content: 41.18

Gene sequence:

>459_bases
ATGTTGTATAAATATATGTGCAAATCATTTGCGCAAATCATTTGCGAGGTGATTGTTTTGAAACGCTTAACCGAGCTGAG
AAAAGAGATCTTAAGGATCATCGAAACCTCTGAAGTGCCACTGAACGCCGAAGAAATCTATCAGAAACTTGAAACAAAGC
CGAATCTATCGTCAGTTTACCGCGGGCTTTCCTTTCTTGAAGACAACGGGATGATAAAATCGATAAGTTTCGACTCCCAT
GTCCGCTTTTTCTATCCTGTGGAAAAAAATCATCCATTGCATTTTATATACTGTAAAAACTGCAGAAAAATAGAGGTCTT
CAACGAATGCTTTGCGGACAGGATTCAGGCACAGATTGAGAAAAAGCACGATTGCACGATAACAGACCATGTGTTTTATT
TCATAGGGCTGTGCAGCGAATGCAGGCACAACTATCCCGGAAGGGGGAGAGAGACATGA

Upstream 100 bases:

>100_bases
CAGGGACGTTTGATCTCCTGAACATCAATTACAATATTCGAAAGATAAGAAGTGCCGATAACCGGCACTTCTTTTTTTGA
TGCTTGACAGCTGGAAGAGA

Downstream 100 bases:

>100_bases
AGAAGCTATCTGTCTTTATAGCGTGGATTATAATAATGGCGAGTCTTGGCTTTTCACTGAACGTTGTAACAACGATAAAT
CCGTATTATCTGATCGTCAA

Product: ferric uptake regulator, Fur family

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MLYKYMCKSFAQIICEVIVLKRLTELRKEILRIIETSEVPLNAEEIYQKLETKPNLSSVYRGLSFLEDNGMIKSISFDSH
VRFFYPVEKNHPLHFIYCKNCRKIEVFNECFADRIQAQIEKKHDCTITDHVFYFIGLCSECRHNYPGRGRET

Sequences:

>Translated_152_residues
MLYKYMCKSFAQIICEVIVLKRLTELRKEILRIIETSEVPLNAEEIYQKLETKPNLSSVYRGLSFLEDNGMIKSISFDSH
VRFFYPVEKNHPLHFIYCKNCRKIEVFNECFADRIQAQIEKKHDCTITDHVFYFIGLCSECRHNYPGRGRET
>Mature_152_residues
MLYKYMCKSFAQIICEVIVLKRLTELRKEILRIIETSEVPLNAEEIYQKLETKPNLSSVYRGLSFLEDNGMIKSISFDSH
VRFFYPVEKNHPLHFIYCKNCRKIEVFNECFADRIQAQIEKKHDCTITDHVFYFIGLCSECRHNYPGRGRET

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18054; Mature: 18054

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYKYMCKSFAQIICEVIVLKRLTELRKEILRIIETSEVPLNAEEIYQKLETKPNLSSVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHH
RGLSFLEDNGMIKSISFDSHVRFFYPVEKNHPLHFIYCKNCRKIEVFNECFADRIQAQIE
HHHHHHHCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KKHDCTITDHVFYFIGLCSECRHNYPGRGRET
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLYKYMCKSFAQIICEVIVLKRLTELRKEILRIIETSEVPLNAEEIYQKLETKPNLSSVY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHH
RGLSFLEDNGMIKSISFDSHVRFFYPVEKNHPLHFIYCKNCRKIEVFNECFADRIQAQIE
HHHHHHHCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KKHDCTITDHVFYFIGLCSECRHNYPGRGRET
HCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]