BacMap

Definition	Eubacterium rectale ATCC 33656, complete genome.
Accession	NC_012781
Length	3,449,685

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The map label for this gene is bcrA [H]

Identifier: 238925932

GI number: 238925932

Start: 3361334

End: 3362194

Strand: Reverse

Name: bcrA [H]

Synonym: EUBREC_3590

Alternate gene names: 238925932

Gene position: 3362194-3361334 (Counterclockwise)

Preceding gene: 238925933

Following gene: 238925931

Centisome position: 97.46

GC content: 42.04

Gene sequence:

>861_bases
ATGAACGCTATTTTGCAGGTTGAGAACTTGACAAAGCAATACGCCGATTTCAAGTTAGACCATGTTTCGTTTTCGGTTCC
GAAAGGAACAATCATGGGGCTTATTGGCGAAAATGGAGCCGGAAAAAGCACAACTATCAATGCTATTCTTGATTTAATTC
ATAAAGATGATGGAACAGTTACTTTTTGGGGGCAGGAATTATCGTCCACAAAACAAATCAAAGAGGATGTTGGCGTAGTG
TTTGACGGAATTAACTTCTATGAAACGCTCACTCCGGCCAAAGTCGGGAAAATTGCTGGTGCTGCCTACAAACAGTGGGA
CGGCCATCTGTTTCAAGACTATCTAAAGCGGTTTCAACTTCCAGCGGATAAGGAAATTAAATCTCTGTCCAAGGGAATGA
AGATGAAGTTGTGTATTGCCGTCGCCCTTTCCCATAACCCCAAGCTACTGATTTTGGACGAAGCGACAAGCGGCCTCGAC
CCTGTAATGCGTGATGATATTCTTGATGTATTTCTTGAATTTGTTCAGGACGAAAATCATTCCATTTTGATGTCCTCGCA
TATCACAACAGATTTAGAAAAAGTCGCAGATTACATTACATTTATCCATCAGGGCAAGGTTCTTTTTTGTAAAACGAAAG
ATGAACTTCGTTATAACTATGGTATTATCCGCTGTGGCGCAGCACTGTTCGACCAGCTCGATAAAGCGGAAATTCTGGCT
TACCGCAAAGATGATTATCAATGGAATGTGCTGGTAGCTGACAAGGAAAAAGCCCGGAGAAAATATAAAAATGCCGTAGT
GGACGACGCAACAATCGACGATATTCTGCTGCTGTATGTGAAAGGAGAGCAAGCAAAATGA

Upstream 100 bases:

>100_bases
AACATTTGCAAGAGGCCGCCGATATTGGGCGGATAAGTGGAATATCGTTGGAAAAACTGATTGAATTACTGACGATATTT
TATCAAGAGGAGGATTAACT

Downstream 100 bases:

>100_bases
AAAGTCTTGTTTTGAAAGATTTATTTAATATCGGCCACAATGCGAAATCTATGCTATTCATCCTTGTGGTTTTTGCCGTT
GCGCTTATTCCGTTTTCCGG

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNAILQVENLTKQYADFKLDHVSFSVPKGTIMGLIGENGAGKSTTINAILDLIHKDDGTVTFWGQELSSTKQIKEDVGVV
FDGINFYETLTPAKVGKIAGAAYKQWDGHLFQDYLKRFQLPADKEIKSLSKGMKMKLCIAVALSHNPKLLILDEATSGLD
PVMRDDILDVFLEFVQDENHSILMSSHITTDLEKVADYITFIHQGKVLFCKTKDELRYNYGIIRCGAALFDQLDKAEILA
YRKDDYQWNVLVADKEKARRKYKNAVVDDATIDDILLLYVKGEQAK

Sequences:

>Translated_286_residues
MNAILQVENLTKQYADFKLDHVSFSVPKGTIMGLIGENGAGKSTTINAILDLIHKDDGTVTFWGQELSSTKQIKEDVGVV
FDGINFYETLTPAKVGKIAGAAYKQWDGHLFQDYLKRFQLPADKEIKSLSKGMKMKLCIAVALSHNPKLLILDEATSGLD
PVMRDDILDVFLEFVQDENHSILMSSHITTDLEKVADYITFIHQGKVLFCKTKDELRYNYGIIRCGAALFDQLDKAEILA
YRKDDYQWNVLVADKEKARRKYKNAVVDDATIDDILLLYVKGEQAK
>Mature_286_residues
MNAILQVENLTKQYADFKLDHVSFSVPKGTIMGLIGENGAGKSTTINAILDLIHKDDGTVTFWGQELSSTKQIKEDVGVV
FDGINFYETLTPAKVGKIAGAAYKQWDGHLFQDYLKRFQLPADKEIKSLSKGMKMKLCIAVALSHNPKLLILDEATSGLD
PVMRDDILDVFLEFVQDENHSILMSSHITTDLEKVADYITFIHQGKVLFCKTKDELRYNYGIIRCGAALFDQLDKAEILA
YRKDDYQWNVLVADKEKARRKYKNAVVDDATIDDILLLYVKGEQAK

Specific function: Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic. Probably responsible for energy coupling to the transport system [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=232, Percent_Identity=28.8793103448276, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI47078218, Length=232, Percent_Identity=28.8793103448276, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27881501, Length=224, Percent_Identity=27.6785714285714, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI30795238, Length=224, Percent_Identity=27.6785714285714, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI21536376, Length=214, Percent_Identity=28.9719626168224, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI27262624, Length=238, Percent_Identity=28.1512605042017, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27262626, Length=238, Percent_Identity=28.1512605042017, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI105990541, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI27477115, Length=210, Percent_Identity=27.1428571428571, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI31657092, Length=226, Percent_Identity=26.5486725663717, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI6005701, Length=213, Percent_Identity=26.7605633802817, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI153792144, Length=238, Percent_Identity=27.7310924369748, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI116734710, Length=200, Percent_Identity=28, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27436953, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI150417984, Length=213, Percent_Identity=26.2910798122066, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI9961252, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4505771, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI9961250, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI21536378, Length=217, Percent_Identity=26.7281105990783, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994943, Length=239, Percent_Identity=30.1255230125523, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786319, Length=231, Percent_Identity=32.4675324675325, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081782, Length=222, Percent_Identity=29.2792792792793, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48995001, Length=227, Percent_Identity=29.9559471365639, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789672, Length=226, Percent_Identity=29.2035398230088, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786398, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788225, Length=228, Percent_Identity=27.6315789473684, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789963, Length=234, Percent_Identity=28.2051282051282, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786698, Length=219, Percent_Identity=28.310502283105, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=25.1101321585903, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787029, Length=219, Percent_Identity=26.4840182648402, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI2367384, Length=222, Percent_Identity=29.2792792792793, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994997, Length=234, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789593, Length=226, Percent_Identity=26.5486725663717, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87081791, Length=254, Percent_Identity=24.0157480314961, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786253, Length=223, Percent_Identity=25.1121076233184, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082268, Length=230, Percent_Identity=25.6521739130435, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790190, Length=256, Percent_Identity=29.296875, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790162, Length=240, Percent_Identity=24.5833333333333, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787759, Length=259, Percent_Identity=23.9382239382239, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789864, Length=250, Percent_Identity=25.2, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789032, Length=209, Percent_Identity=26.7942583732057, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787500, Length=218, Percent_Identity=24.7706422018349, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786872, Length=224, Percent_Identity=29.4642857142857, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789751, Length=210, Percent_Identity=29.0476190476191, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787164, Length=239, Percent_Identity=25.9414225941423, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789962, Length=218, Percent_Identity=27.0642201834862, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994883, Length=234, Percent_Identity=25.2136752136752, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790739, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081834, Length=208, Percent_Identity=28.8461538461538, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081709, Length=219, Percent_Identity=21.4611872146119, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789891, Length=209, Percent_Identity=24.8803827751196, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788165, Length=200, Percent_Identity=26.5, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787792, Length=222, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=191, Percent_Identity=24.6073298429319, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787712, Length=213, Percent_Identity=21.1267605633803, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786563, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788897, Length=223, Percent_Identity=24.2152466367713, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788472, Length=217, Percent_Identity=24.4239631336406, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788540, Length=194, Percent_Identity=23.7113402061856, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=228, Percent_Identity=21.9298245614035, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=225, Percent_Identity=24.8888888888889, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1790544, Length=233, Percent_Identity=21.8884120171674, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71983516, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71983510, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17510237, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534520, Length=229, Percent_Identity=29.2576419213974, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=208, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193208177, Length=240, Percent_Identity=26.25, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17565586, Length=238, Percent_Identity=25.2100840336134, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17567269, Length=243, Percent_Identity=27.1604938271605, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=248, Percent_Identity=25.4032258064516, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324985, Length=205, Percent_Identity=28.2926829268293, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321752, Length=185, Percent_Identity=29.1891891891892, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI85725262, Length=208, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362751, Length=211, Percent_Identity=28.436018957346, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24650853, Length=204, Percent_Identity=30.3921568627451, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650855, Length=204, Percent_Identity=30.3921568627451, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582014, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24582012, Length=230, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574150, Length=216, Percent_Identity=28.2407407407407, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007328, Length=216, Percent_Identity=28.2407407407407, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666092, Length=216, Percent_Identity=28.2407407407407, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI116007184, Length=235, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI221500365, Length=235, Percent_Identity=25.531914893617, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI221512771, Length=231, Percent_Identity=27.7056277056277, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643674, Length=233, Percent_Identity=25.7510729613734, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357907, Length=219, Percent_Identity=28.7671232876712, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648314, Length=218, Percent_Identity=26.1467889908257, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573571, Length=191, Percent_Identity=25.130890052356, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 32232; Mature: 32232

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAILQVENLTKQYADFKLDHVSFSVPKGTIMGLIGENGAGKSTTINAILDLIHKDDGTV
CCCEEEHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCE
TFWGQELSSTKQIKEDVGVVFDGINFYETLTPAKVGKIAGAAYKQWDGHLFQDYLKRFQL
EEECHHHHHHHHHHHHHCEEECCCCHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
PADKEIKSLSKGMKMKLCIAVALSHNPKLLILDEATSGLDPVMRDDILDVFLEFVQDENH
CCCHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
SILMSSHITTDLEKVADYITFIHQGKVLFCKTKDELRYNYGIIRCGAALFDQLDKAEILA
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEECHHHHHCCCCHHEEE
YRKDDYQWNVLVADKEKARRKYKNAVVDDATIDDILLLYVKGEQAK
EECCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNAILQVENLTKQYADFKLDHVSFSVPKGTIMGLIGENGAGKSTTINAILDLIHKDDGTV
CCCEEEHHHHHHHHHCCEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCE
TFWGQELSSTKQIKEDVGVVFDGINFYETLTPAKVGKIAGAAYKQWDGHLFQDYLKRFQL
EEECHHHHHHHHHHHHHCEEECCCCHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
PADKEIKSLSKGMKMKLCIAVALSHNPKLLILDEATSGLDPVMRDDILDVFLEFVQDENH
CCCHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
SILMSSHITTDLEKVADYITFIHQGKVLFCKTKDELRYNYGIIRCGAALFDQLDKAEILA
EEEEECCCHHHHHHHHHHHHHHHCCCEEEEECHHHHHHCCCCEEECHHHHHCCCCHHEEE
YRKDDYQWNVLVADKEKARRKYKNAVVDDATIDDILLLYVKGEQAK
EECCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7476193 [H]