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The map label for this gene is yesM [H]

Identifier: 238925863

GI number: 238925863

Start: 3292585

End: 3294480

Strand: Direct

Name: yesM [H]

Synonym: EUBREC_3521

Alternate gene names: 238925863

Gene position: 3292585-3294480 (Clockwise)

Preceding gene: 238925857

Following gene: 238925864

Centisome position: 95.45

GC content: 39.72

Gene sequence:

>1896_bases
ATGCAAGATTTCATTGACGAAAGCGTTTTTGATAGATTTTGCCCGGATACAATACAAGGAGATTTTATGAAACATTCAAA
AAAAGGGTCCAGAGGTCCACGATTATACTTTTCCCATTTTCAAAACAGGATTTTATGTGCGTTTTTGCTGTGCACATTGA
TTCCTATTTTCATCATAGGCGGAATTTCCTATGCTGTTTCTTATAACATTGCTAAAGATAAGATTCTGAATGCATCTATT
TCCGCTGATGCACAGCTGCATACACAGTTTGATAACCGCTTGCAGCAAGTGGAAAATATAGCCGATACGCTTCAATATAA
TATGTACAACCTGATGCAGGCAGATGCACCCATGGACACTCTGGCTATGCTTTCCGAGATTCGGAGCAATCTGTCCATGT
TTAAGACATCCTTTGATCTGGCCTATATCAATATATTTCTTCCGGACGAGCATATGGCATCCAGCGAAAGCTTATACTTT
TTCCCTATGTCTAAGCTTTCTGACTTTCAGATTCCAAAAGAAGTTCTGGAAAATCCGGGAACATCCTCTGTCTGGTTTTA
TCAGGATCTGCTGTCTGTTCCGTTTCTTGTGAATAACAGCTACCATATTACGAATTCTGTTTCCTGTTGCAGAGTTTTAA
AACATCCGGATACAGACAGCATAAAGTATGCTTATATAATTTATCTGGACGCATCTGAATTTTCCTCCATTCTACAGGAA
ATTTTCCAGGATAATCAGATCACCAGCTATATCCTTACAGACAACGGAAAAATCGTTGCCAGCAACAATCCTTCTTTGCT
TTCTGCATCTCTTGACGAAGAAAAACTGGATTTCTTATACAACAAGGGAGATTCTCTAAAAAAGAGAGCTCACACTAATT
ATCACACTACTACTTTACGAAACGGCTGGCTACAGGTGACAGAGATACCGGATTCTTATATCATGCAAAACACGCATATA
CTGATCAAAAGTATCCTCCTGACAATCCTGATCTCTCTTCCGCTGACGATTCTGGTTGTGGTTCTGATCTCGAAGAATCT
TACCAGACGAATCAAGACACTATCCAGGGCTATGGAAACACTACAATTAGATGCATCCGACACCAACATGAAGGCACTGG
TACCACAGGATCGTGCACCTGAAACCTTCGATGAGATTGATAAACTGGGGATAACCTTTGAAAAAATGCAGCATTCCCTG
AATGACAATCTGCAGTCTATTCTGGAACTGTCACTGACGGAAGAACGGCTAAAATACCAGCTTCTCCAATCCCAGATCAA
TCCACATTTTCTTTATAATATTCTGGGATCCATCCAGACCTGTCAGTCCCTTGGAAAGCTGGATATTGCCAATCAGATGC
TGACGAATCTTACACGTTTTTACCGCATGACACTCAGAAAGTCGGAAGACCTGATCTCCATCCGGGACGAACTGACCATC
GCACAGCTTTATCTGGAAATGGAAAAATTATGCCATAATGATAATCTTACCTGGGAGATCAATATGGAAGACGGCATTGA
CAACTTCCTGATCTGCAAATTCACACTGCAGCCATTTCTGGAAAACAGTATTATGCATGGTCTCTCTCAGAAAACGCCGG
AGGTTCATATCTCCATTGATCTTTCCTACGGAGATGATACGGTTATTATTGTGATCACAGATAACGGAATCGGAATGGCA
AAAGAACAGCTTTTAGAATTGCAGAAAACATTGGATGAAAAAATTGTTAATTATGAAAAACACTTTGGTATTGGAAATGT
AAACAAACGAATCTCCAATCCTTATTTTGGAAATGGTAGGATATCTGTAGAAAGTTGTCTGTATGAAGGCACTTCCATTA
CCATTGAATTTGATCAGATGGAGAAATATGATGAAGAATGTAATGATTGTAGATGA

Upstream 100 bases:

>100_bases
TTATCCTTGTTAAAAGCATTTTTTTAATCTATAATAAGAATAGAAATTGATCATATATAATAGTGTTCTGGCATGAGCAT
GCCGAAATACAAACGATCAC

Downstream 100 bases:

>100_bases
CAACTGCCTCACCGCAGAAGGCATCGAAAAAAATATTGACTGGAGTGCTCTGGATGCCACTGTGATCGCCGTAGAATATA
ACAGTCTTTCCGCTCTGGAC

Product: two-component sensor kinase YesM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MQDFIDESVFDRFCPDTIQGDFMKHSKKGSRGPRLYFSHFQNRILCAFLLCTLIPIFIIGGISYAVSYNIAKDKILNASI
SADAQLHTQFDNRLQQVENIADTLQYNMYNLMQADAPMDTLAMLSEIRSNLSMFKTSFDLAYINIFLPDEHMASSESLYF
FPMSKLSDFQIPKEVLENPGTSSVWFYQDLLSVPFLVNNSYHITNSVSCCRVLKHPDTDSIKYAYIIYLDASEFSSILQE
IFQDNQITSYILTDNGKIVASNNPSLLSASLDEEKLDFLYNKGDSLKKRAHTNYHTTTLRNGWLQVTEIPDSYIMQNTHI
LIKSILLTILISLPLTILVVVLISKNLTRRIKTLSRAMETLQLDASDTNMKALVPQDRAPETFDEIDKLGITFEKMQHSL
NDNLQSILELSLTEERLKYQLLQSQINPHFLYNILGSIQTCQSLGKLDIANQMLTNLTRFYRMTLRKSEDLISIRDELTI
AQLYLEMEKLCHNDNLTWEINMEDGIDNFLICKFTLQPFLENSIMHGLSQKTPEVHISIDLSYGDDTVIIVITDNGIGMA
KEQLLELQKTLDEKIVNYEKHFGIGNVNKRISNPYFGNGRISVESCLYEGTSITIEFDQMEKYDEECNDCR

Sequences:

>Translated_631_residues
MQDFIDESVFDRFCPDTIQGDFMKHSKKGSRGPRLYFSHFQNRILCAFLLCTLIPIFIIGGISYAVSYNIAKDKILNASI
SADAQLHTQFDNRLQQVENIADTLQYNMYNLMQADAPMDTLAMLSEIRSNLSMFKTSFDLAYINIFLPDEHMASSESLYF
FPMSKLSDFQIPKEVLENPGTSSVWFYQDLLSVPFLVNNSYHITNSVSCCRVLKHPDTDSIKYAYIIYLDASEFSSILQE
IFQDNQITSYILTDNGKIVASNNPSLLSASLDEEKLDFLYNKGDSLKKRAHTNYHTTTLRNGWLQVTEIPDSYIMQNTHI
LIKSILLTILISLPLTILVVVLISKNLTRRIKTLSRAMETLQLDASDTNMKALVPQDRAPETFDEIDKLGITFEKMQHSL
NDNLQSILELSLTEERLKYQLLQSQINPHFLYNILGSIQTCQSLGKLDIANQMLTNLTRFYRMTLRKSEDLISIRDELTI
AQLYLEMEKLCHNDNLTWEINMEDGIDNFLICKFTLQPFLENSIMHGLSQKTPEVHISIDLSYGDDTVIIVITDNGIGMA
KEQLLELQKTLDEKIVNYEKHFGIGNVNKRISNPYFGNGRISVESCLYEGTSITIEFDQMEKYDEECNDCR
>Mature_631_residues
MQDFIDESVFDRFCPDTIQGDFMKHSKKGSRGPRLYFSHFQNRILCAFLLCTLIPIFIIGGISYAVSYNIAKDKILNASI
SADAQLHTQFDNRLQQVENIADTLQYNMYNLMQADAPMDTLAMLSEIRSNLSMFKTSFDLAYINIFLPDEHMASSESLYF
FPMSKLSDFQIPKEVLENPGTSSVWFYQDLLSVPFLVNNSYHITNSVSCCRVLKHPDTDSIKYAYIIYLDASEFSSILQE
IFQDNQITSYILTDNGKIVASNNPSLLSASLDEEKLDFLYNKGDSLKKRAHTNYHTTTLRNGWLQVTEIPDSYIMQNTHI
LIKSILLTILISLPLTILVVVLISKNLTRRIKTLSRAMETLQLDASDTNMKALVPQDRAPETFDEIDKLGITFEKMQHSL
NDNLQSILELSLTEERLKYQLLQSQINPHFLYNILGSIQTCQSLGKLDIANQMLTNLTRFYRMTLRKSEDLISIRDELTI
AQLYLEMEKLCHNDNLTWEINMEDGIDNFLICKFTLQPFLENSIMHGLSQKTPEVHISIDLSYGDDTVIIVITDNGIGMA
KEQLLELQKTLDEKIVNYEKHFGIGNVNKRISNPYFGNGRISVESCLYEGTSITIEFDQMEKYDEECNDCR

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=175, Percent_Identity=29.1428571428571, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788446, Length=145, Percent_Identity=30.3448275862069, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72367; Mature: 72367

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDFIDESVFDRFCPDTIQGDFMKHSKKGSRGPRLYFSHFQNRILCAFLLCTLIPIFIIG
CCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GISYAVSYNIAKDKILNASISADAQLHTQFDNRLQQVENIADTLQYNMYNLMQADAPMDT
HHHHEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAMLSEIRSNLSMFKTSFDLAYINIFLPDEHMASSESLYFFPMSKLSDFQIPKEVLENPG
HHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCCEEEEECCCCCCCCCCHHHHCCCC
TSSVWFYQDLLSVPFLVNNSYHITNSVSCCRVLKHPDTDSIKYAYIIYLDASEFSSILQE
CCCCHHHHHHHHCCEEECCCEEECCCHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHH
IFQDNQITSYILTDNGKIVASNNPSLLSASLDEEKLDFLYNKGDSLKKRAHTNYHTTTLR
HHCCCCEEEEEEECCCEEEECCCCCEEECCCCHHHHHHHHCCCCHHHHHHCCCCCEEEEC
NGWLQVTEIPDSYIMQNTHILIKSILLTILISLPLTILVVVLISKNLTRRIKTLSRAMET
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLDASDTNMKALVPQDRAPETFDEIDKLGITFEKMQHSLNDNLQSILELSLTEERLKYQ
HCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQSQINPHFLYNILGSIQTCQSLGKLDIANQMLTNLTRFYRMTLRKSEDLISIRDELTI
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQLYLEMEKLCHNDNLTWEINMEDGIDNFLICKFTLQPFLENSIMHGLSQKTPEVHISID
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEEE
LSYGDDTVIIVITDNGIGMAKEQLLELQKTLDEKIVNYEKHFGIGNVNKRISNPYFGNGR
EECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCE
ISVESCLYEGTSITIEFDQMEKYDEECNDCR
EEHHHHHCCCCEEEEEEHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDFIDESVFDRFCPDTIQGDFMKHSKKGSRGPRLYFSHFQNRILCAFLLCTLIPIFIIG
CCHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GISYAVSYNIAKDKILNASISADAQLHTQFDNRLQQVENIADTLQYNMYNLMQADAPMDT
HHHHEEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAMLSEIRSNLSMFKTSFDLAYINIFLPDEHMASSESLYFFPMSKLSDFQIPKEVLENPG
HHHHHHHHHHHHHHHHCCCEEEEEEEECCHHCCCCCCEEEEECCCCCCCCCCHHHHCCCC
TSSVWFYQDLLSVPFLVNNSYHITNSVSCCRVLKHPDTDSIKYAYIIYLDASEFSSILQE
CCCCHHHHHHHHCCEEECCCEEECCCHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHH
IFQDNQITSYILTDNGKIVASNNPSLLSASLDEEKLDFLYNKGDSLKKRAHTNYHTTTLR
HHCCCCEEEEEEECCCEEEECCCCCEEECCCCHHHHHHHHCCCCHHHHHHCCCCCEEEEC
NGWLQVTEIPDSYIMQNTHILIKSILLTILISLPLTILVVVLISKNLTRRIKTLSRAMET
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQLDASDTNMKALVPQDRAPETFDEIDKLGITFEKMQHSLNDNLQSILELSLTEERLKYQ
HCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQSQINPHFLYNILGSIQTCQSLGKLDIANQMLTNLTRFYRMTLRKSEDLISIRDELTI
HHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQLYLEMEKLCHNDNLTWEINMEDGIDNFLICKFTLQPFLENSIMHGLSQKTPEVHISID
HHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHHCCCCEEEEEEE
LSYGDDTVIIVITDNGIGMAKEQLLELQKTLDEKIVNYEKHFGIGNVNKRISNPYFGNGR
EECCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCE
ISVESCLYEGTSITIEFDQMEKYDEECNDCR
EEHHHHHCCCCEEEEEEHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]