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The map label for this gene is gltA [H]

Identifier: 238925831

GI number: 238925831

Start: 3267356

End: 3268720

Strand: Reverse

Name: gltA [H]

Synonym: EUBREC_3489

Alternate gene names: 238925831

Gene position: 3268720-3267356 (Counterclockwise)

Preceding gene: 238925832

Following gene: 238925830

Centisome position: 94.75

GC content: 35.68

Gene sequence:

>1365_bases
ATGAAAGGAGCGATTCAAATGAGCAATTTGGAAAATTATATGAAACGGCAAGCAATTTTTTGTGAACAAAATGATAGCAT
TAGTAAGAATCTGTATTCAGAGTATGGTGTAAAAAGAGGCTTACGAGATGAAAAAGGCCAAGGTGTGTTGACGGGGCTTA
CAAATATTTCTGATATAAAAGCTTTTGAATATCATGATGGAGTAAAGAGTCCATGTGATGGCGAGTTATCTTATCGTGGT
TATAATATAAAAGATTTAGTAACAGGAAGTAAAGGAAAAAGGTTTGTCTTTGAAGAAGGAGCATATCTTCTTTTATTCGG
AGAATTGCCAACTGATACACAGTTAATGGAATTTCAGGGAAGACTATCTGATTGTATGGAACTACCGACTAACTTTACCA
GAGATGTCATTATGAAAGCACCTACATCAGATATTATGGGTTCTATGACTCGAAGTATTCTTACATTGGGCTCTTACGAT
AAGGAGAAAGAAAGTCTTGGAATTCCGAATGTGCTAAGGCAGAGTATGCAGTTGATCGCAGTATTTCCTATGTTAGCAGT
ATATGCATACCATGCTTATTGTCATTATGAAAAAAACGAAAGTATGTATATTCATAGACCTGAAAAAGATTTATCTATTG
CTGAAAATTTCCTGCGCCTATTAAGACCAGATACAAAATTCACAGAACTGGAAGCAAGAGTACTGGATATAGCATTATTG
TTACATATGGAACATGGTGGTGGTAACAATTCTACATTCACTACACGAGTAGTAACATCTTCAGGTTCAGATACTTATTC
TGTTATTTCAGCAGCAATGTCATCCTTAAAAGGAAAAAAACATGGCGGTGCAAATCTGATGGTAATGAATATGATGGATG
ATATTAAAAGTCATGTGAAGGATTATGAAGACGAAGAGGAAATTGCATCATATCTGAGTAAGATTTTGAAGAAAGAGGCG
TTTGATCAGAAAGGACTTATTTATGGAATGGGACATGCTGTATATTCTATTTCAGATCCGAGAGAAAGAGTGTTCAAAGG
CTTTGTAGAACAACTCGCAAGGGATAAAGGACGTGAGAAAGATATGACCCTTTATAACAATATTGAGAAGATTGCACCTA
AGTTGATTGCAAAGCAGCGTCAGATATTCAAAGGAGTAAGTCCTAATATAGATTTCTATAGTGGTTTTGTGTATGACATG
TTGAATATTCCAAGAGAATTGTACACGCCATTATTTGCGATAGCAAGAATTGCTGGTTGGAGTGCACATCGCCTGGAAGA
ATTGATAACTACAGATAAGATCATTCGCCCGGCATATAAGAGTCTAGTCAGCAAAAAAGAATATATAGAAAGAGAGGAAC
GATAA

Upstream 100 bases:

>100_bases
TCCATTGTATTGTATTGCTAATGAATAAGAATAAGAACAGACAATGCTGAATGCTCTGGAAACAAGAATATCTGAGTATA
GTATGTAAGTTCGTAACAGA

Downstream 100 bases:

>100_bases
TATGAGAGCAGGAACCAGTGCAGAGGAGTTTTTTTTAAAGAGCATCAATGTTGAAAGCATATTTGAATTTGTTGAAAGAA
CAGATTATTTGTTCCTTTAT

Product: citrate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MKGAIQMSNLENYMKRQAIFCEQNDSISKNLYSEYGVKRGLRDEKGQGVLTGLTNISDIKAFEYHDGVKSPCDGELSYRG
YNIKDLVTGSKGKRFVFEEGAYLLLFGELPTDTQLMEFQGRLSDCMELPTNFTRDVIMKAPTSDIMGSMTRSILTLGSYD
KEKESLGIPNVLRQSMQLIAVFPMLAVYAYHAYCHYEKNESMYIHRPEKDLSIAENFLRLLRPDTKFTELEARVLDIALL
LHMEHGGGNNSTFTTRVVTSSGSDTYSVISAAMSSLKGKKHGGANLMVMNMMDDIKSHVKDYEDEEEIASYLSKILKKEA
FDQKGLIYGMGHAVYSISDPRERVFKGFVEQLARDKGREKDMTLYNNIEKIAPKLIAKQRQIFKGVSPNIDFYSGFVYDM
LNIPRELYTPLFAIARIAGWSAHRLEELITTDKIIRPAYKSLVSKKEYIEREER

Sequences:

>Translated_454_residues
MKGAIQMSNLENYMKRQAIFCEQNDSISKNLYSEYGVKRGLRDEKGQGVLTGLTNISDIKAFEYHDGVKSPCDGELSYRG
YNIKDLVTGSKGKRFVFEEGAYLLLFGELPTDTQLMEFQGRLSDCMELPTNFTRDVIMKAPTSDIMGSMTRSILTLGSYD
KEKESLGIPNVLRQSMQLIAVFPMLAVYAYHAYCHYEKNESMYIHRPEKDLSIAENFLRLLRPDTKFTELEARVLDIALL
LHMEHGGGNNSTFTTRVVTSSGSDTYSVISAAMSSLKGKKHGGANLMVMNMMDDIKSHVKDYEDEEEIASYLSKILKKEA
FDQKGLIYGMGHAVYSISDPRERVFKGFVEQLARDKGREKDMTLYNNIEKIAPKLIAKQRQIFKGVSPNIDFYSGFVYDM
LNIPRELYTPLFAIARIAGWSAHRLEELITTDKIIRPAYKSLVSKKEYIEREER
>Mature_454_residues
MKGAIQMSNLENYMKRQAIFCEQNDSISKNLYSEYGVKRGLRDEKGQGVLTGLTNISDIKAFEYHDGVKSPCDGELSYRG
YNIKDLVTGSKGKRFVFEEGAYLLLFGELPTDTQLMEFQGRLSDCMELPTNFTRDVIMKAPTSDIMGSMTRSILTLGSYD
KEKESLGIPNVLRQSMQLIAVFPMLAVYAYHAYCHYEKNESMYIHRPEKDLSIAENFLRLLRPDTKFTELEARVLDIALL
LHMEHGGGNNSTFTTRVVTSSGSDTYSVISAAMSSLKGKKHGGANLMVMNMMDDIKSHVKDYEDEEEIASYLSKILKKEA
FDQKGLIYGMGHAVYSISDPRERVFKGFVEQLARDKGREKDMTLYNNIEKIAPKLIAKQRQIFKGVSPNIDFYSGFVYDM
LNIPRELYTPLFAIARIAGWSAHRLEELITTDKIIRPAYKSLVSKKEYIEREER

Specific function: Catalyzes The Synthesis Of 2-Methylcitrate From Propionyl-CoA And Oxaloacetate. Also Catalyzes The Condensation Of Oxaloacetate With Acetyl-CoA But With A Lower Specificity. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=405, Percent_Identity=27.1604938271605, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786527, Length=365, Percent_Identity=34.2465753424658, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1786939, Length=375, Percent_Identity=29.6, Blast_Score=131, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17555174, Length=416, Percent_Identity=26.6826923076923, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325257, Length=377, Percent_Identity=27.8514588859416, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319850, Length=429, Percent_Identity=25.8741258741259, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324328, Length=411, Percent_Identity=26.0340632603406, Blast_Score=93, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24640124, Length=365, Percent_Identity=26.8493150684932, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24640126, Length=365, Percent_Identity=26.8493150684932, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21356863, Length=247, Percent_Identity=28.3400809716599, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011278
- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 51702; Mature: 51702

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGAIQMSNLENYMKRQAIFCEQNDSISKNLYSEYGVKRGLRDEKGQGVLTGLTNISDIK
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
AFEYHDGVKSPCDGELSYRGYNIKDLVTGSKGKRFVFEEGAYLLLFGELPTDTQLMEFQG
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHH
RLSDCMELPTNFTRDVIMKAPTSDIMGSMTRSILTLGSYDKEKESLGIPNVLRQSMQLIA
HHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
VFPMLAVYAYHAYCHYEKNESMYIHRPEKDLSIAENFLRLLRPDTKFTELEARVLDIALL
HHHHHHHHHHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHMEHGGGNNSTFTTRVVTSSGSDTYSVISAAMSSLKGKKHGGANLMVMNMMDDIKSHVK
HEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
DYEDEEEIASYLSKILKKEAFDQKGLIYGMGHAVYSISDPRERVFKGFVEQLARDKGREK
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCC
DMTLYNNIEKIAPKLIAKQRQIFKGVSPNIDFYSGFVYDMLNIPRELYTPLFAIARIAGW
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SAHRLEELITTDKIIRPAYKSLVSKKEYIEREER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKGAIQMSNLENYMKRQAIFCEQNDSISKNLYSEYGVKRGLRDEKGQGVLTGLTNISDIK
CCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
AFEYHDGVKSPCDGELSYRGYNIKDLVTGSKGKRFVFEEGAYLLLFGELPTDTQLMEFQG
HHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCEEEEECCCCCCHHHHHHHH
RLSDCMELPTNFTRDVIMKAPTSDIMGSMTRSILTLGSYDKEKESLGIPNVLRQSMQLIA
HHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHH
VFPMLAVYAYHAYCHYEKNESMYIHRPEKDLSIAENFLRLLRPDTKFTELEARVLDIALL
HHHHHHHHHHHHHHEEECCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LHMEHGGGNNSTFTTRVVTSSGSDTYSVISAAMSSLKGKKHGGANLMVMNMMDDIKSHVK
HEEECCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHH
DYEDEEEIASYLSKILKKEAFDQKGLIYGMGHAVYSISDPRERVFKGFVEQLARDKGREK
CCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHCCCCC
DMTLYNNIEKIAPKLIAKQRQIFKGVSPNIDFYSGFVYDMLNIPRELYTPLFAIARIAGW
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SAHRLEELITTDKIIRPAYKSLVSKKEYIEREER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]