Click here to switch to the map view.

The map label for this gene is cbh [H]

Identifier: 238925822

GI number: 238925822

Start: 3262498

End: 3262722

Strand: Reverse

Name: cbh [H]

Synonym: EUBREC_3480

Alternate gene names: 238925822

Gene position: 3262722-3262498 (Counterclockwise)

Preceding gene: 238925823

Following gene: 238925821

Centisome position: 94.58

GC content: 39.56

Gene sequence:

>225_bases
ATGTGTACAGCAGCAACTTACAAAACAAAAGATTTTTATATGGGCAGAACGCTTGATTATGAATTTTCCTATGGGGAACA
GATCACGATAACACCAAGAAATTACGAATTTGATTTCCGGTTTGCCGGGAAGATAAAAAGCCATTATGCTTTGATCGGAA
TGGCATTTGTTGCAGGAGGTTATCCGCTTCTGTCCAAGGGCGAAGTCAGATGGCAGAATAAATAA

Upstream 100 bases:

>100_bases
CGAAAAGTACCGCACAGGACGGAGTGCATATTTACGGATCGGACAGTTGTTTATGAGATTGTTTGCAGGACTATTATAGC
AGAAAGAAGAGGTGTTCGAT

Downstream 100 bases:

>100_bases
TACGAAAATGCACGGAGAAAGCATAACGCAGAACAACAGGAGGAAAGAACATGAAAGAAGTTAAAACACCGAAAAAACCA
CTGGCATATTATTATGGGAT

Product: penicillin V acylase related amidase

Products: NA

Alternate protein names: Bile salt hydrolase; Conjugated bile acid hydrolase; CBAH [H]

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MCTAATYKTKDFYMGRTLDYEFSYGEQITITPRNYEFDFRFAGKIKSHYALIGMAFVAGGYPLLSKGEVRWQNK

Sequences:

>Translated_74_residues
MCTAATYKTKDFYMGRTLDYEFSYGEQITITPRNYEFDFRFAGKIKSHYALIGMAFVAGGYPLLSKGEVRWQNK
>Mature_74_residues
MCTAATYKTKDFYMGRTLDYEFSYGEQITITPRNYEFDFRFAGKIKSHYALIGMAFVAGGYPLLSKGEVRWQNK

Specific function: The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C59 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003199 [H]

Pfam domain/function: PF02275 CBAH [H]

EC number: =3.5.1.24 [H]

Molecular weight: Translated: 8595; Mature: 8595

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTAATYKTKDFYMGRTLDYEFSYGEQITITPRNYEFDFRFAGKIKSHYALIGMAFVAGG
CCCCCCCCCCCEECCCEEEEEECCCCEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCC
YPLLSKGEVRWQNK
CCCCCCCEEEEECC
>Mature Secondary Structure
MCTAATYKTKDFYMGRTLDYEFSYGEQITITPRNYEFDFRFAGKIKSHYALIGMAFVAGG
CCCCCCCCCCCEECCCEEEEEECCCCEEEECCCCCEEEEEECCCCCCCEEEEEEEECCCC
YPLLSKGEVRWQNK
CCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1476424; 12566566 [H]