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The map label for this gene is tlpB [H]

Identifier: 238925735

GI number: 238925735

Start: 3203938

End: 3205407

Strand: Reverse

Name: tlpB [H]

Synonym: EUBREC_3392

Alternate gene names: 238925735

Gene position: 3205407-3203938 (Counterclockwise)

Preceding gene: 238925736

Following gene: 238925734

Centisome position: 92.92

GC content: 42.18

Gene sequence:

>1470_bases
ATGATGGTGGAAACAAAAGAAATTTCGGAATTGACGCGGTCGAATCGCATTGCGATGCTGTCACATATCAGTACGGTAAC
GGTTATGGTATTTTTTATGATATGGGAAAGCGTAAGAGGACAACTGTCTCCGGTATATATGACAATCGCTACGGTCGTTG
GTGTTATACCTTTGATTGGCGAGGTGATTTGTTGGAAATCTAATACGGAACATGCGATGATCAAACATCTGGTTTCCTAT
GGATTTGCATTGTTTTACACAATATGTCTTTTTACCTCACCGACAAATCTGATTTATGTATTTGTAATTCCGATGATTTT
TGTTGTCACCATTTACAGTGACACACGTTATCTTCTTCTGATTAATACAGGTACCATATTAGAGAGTATCATTGTTGTTG
TGATCGGTGCGACAAAAGGCGGTTTTGGGTATCATGGAATCGAAGCAGCAGTTGTACAGATTGTTGTTATGATTATGGTT
GGAGCGAATTCTGTTTTGACTACAAAAGTGATTCGCGAAAACACAAGAAAGAGATTTACAGAAGTGGCGCAGGCAAAAGC
AGAGGCTGAAAATCTTCTGGAAAGAAATGAGGAACTTGATCAGCAGATTTCCGGCAATATTGCAGATATCAATGTACGTT
TCGAAAAGCTGACAGCGGCATCTAAGACAACGACTGAGGCAATGCAGGAAGTATCTGCAGGTGCTACTGATACCGCAGAA
CATGTGCAGAATCAGTTGGAACAGACACATGCAATTCAGGACAAGGTGGATGAAGTTGCAACCGCTGTGGAAGAAATCGG
AAACAGCATGACGCTTACTCTGAAAGCGTTAGCGGAAGGCAAACAGGATATCGAGCACCTGGCATCGGAAGTTGAAGCTT
CTGTTGATAATGGAACCGAGGTTACAGAAAAACTGGAAAATCTGAACCAGTATATGGATGAAATGAATTCCATTGTAGAA
CTGATTGGAGGAATTACGAACCAAACAAGTCTTCTTGCATTAAATGCGAGCATTGAAGCAGCCCGTGCCGGAGAGGCAGG
AAGAGGATTTTCTGTCGTTGCAACAGAAATTTCCGGTATGGCAACGAGAACCAAAGAAGCAACCGTACATATTACAGAGT
TGATCAGCAACGTGTCCAATGCAATCATGGAGGTGGTCGGTGTTGTCTCCAATATGATAGATGGAATTAACGAAGAGAAG
ACTGGTGCATCGAATGCAGAAGAAAGCTTTGAAAGTATCGAGGACAATACGCGGGCAATTCAGAAAAATGCAGATACTCT
TTCAAGAAGCATTTCCGAGTTGCAGAATGCAAATAAGGAAATTATAGATTCCATTCAGACAATCTCAGCAATTTCCCAGC
AGGTATCGGCGCACGCAGGCGAGACGATGCAGGCAGAGGAAGAAAATTTGAATGTAATGCAGGATGTAAGTGCAATTATG
CAGAAGCTGGCAACACTGGCTACCCATTAA

Upstream 100 bases:

>100_bases
GCAAAGGTATTTGAGACACATACACCATTAAAGATAGAATATCAGGATGCGTAAGAAATAATATAAGGATAAGTAGGAAA
ACTTTTCTAGAGGAGGTATT

Downstream 100 bases:

>100_bases
TAAGGGAAAATAAACAATAAAAGAAAGCTCTAATACTGTGACGAACTGCATAAATGAACTGAAAAATGTCATTTCATCAC
ATAAAAGTGGTGAAATGGCA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MMVETKEISELTRSNRIAMLSHISTVTVMVFFMIWESVRGQLSPVYMTIATVVGVIPLIGEVICWKSNTEHAMIKHLVSY
GFALFYTICLFTSPTNLIYVFVIPMIFVVTIYSDTRYLLLINTGTILESIIVVVIGATKGGFGYHGIEAAVVQIVVMIMV
GANSVLTTKVIRENTRKRFTEVAQAKAEAENLLERNEELDQQISGNIADINVRFEKLTAASKTTTEAMQEVSAGATDTAE
HVQNQLEQTHAIQDKVDEVATAVEEIGNSMTLTLKALAEGKQDIEHLASEVEASVDNGTEVTEKLENLNQYMDEMNSIVE
LIGGITNQTSLLALNASIEAARAGEAGRGFSVVATEISGMATRTKEATVHITELISNVSNAIMEVVGVVSNMIDGINEEK
TGASNAEESFESIEDNTRAIQKNADTLSRSISELQNANKEIIDSIQTISAISQQVSAHAGETMQAEEENLNVMQDVSAIM
QKLATLATH

Sequences:

>Translated_489_residues
MMVETKEISELTRSNRIAMLSHISTVTVMVFFMIWESVRGQLSPVYMTIATVVGVIPLIGEVICWKSNTEHAMIKHLVSY
GFALFYTICLFTSPTNLIYVFVIPMIFVVTIYSDTRYLLLINTGTILESIIVVVIGATKGGFGYHGIEAAVVQIVVMIMV
GANSVLTTKVIRENTRKRFTEVAQAKAEAENLLERNEELDQQISGNIADINVRFEKLTAASKTTTEAMQEVSAGATDTAE
HVQNQLEQTHAIQDKVDEVATAVEEIGNSMTLTLKALAEGKQDIEHLASEVEASVDNGTEVTEKLENLNQYMDEMNSIVE
LIGGITNQTSLLALNASIEAARAGEAGRGFSVVATEISGMATRTKEATVHITELISNVSNAIMEVVGVVSNMIDGINEEK
TGASNAEESFESIEDNTRAIQKNADTLSRSISELQNANKEIIDSIQTISAISQQVSAHAGETMQAEEENLNVMQDVSAIM
QKLATLATH
>Mature_489_residues
MMVETKEISELTRSNRIAMLSHISTVTVMVFFMIWESVRGQLSPVYMTIATVVGVIPLIGEVICWKSNTEHAMIKHLVSY
GFALFYTICLFTSPTNLIYVFVIPMIFVVTIYSDTRYLLLINTGTILESIIVVVIGATKGGFGYHGIEAAVVQIVVMIMV
GANSVLTTKVIRENTRKRFTEVAQAKAEAENLLERNEELDQQISGNIADINVRFEKLTAASKTTTEAMQEVSAGATDTAE
HVQNQLEQTHAIQDKVDEVATAVEEIGNSMTLTLKALAEGKQDIEHLASEVEASVDNGTEVTEKLENLNQYMDEMNSIVE
LIGGITNQTSLLALNASIEAARAGEAGRGFSVVATEISGMATRTKEATVHITELISNVSNAIMEVVGVVSNMIDGINEEK
TGASNAEESFESIEDNTRAIQKNADTLSRSISELQNANKEIIDSIQTISAISQQVSAHAGETMQAEEENLNVMQDVSAIM
QKLATLATH

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=156, Percent_Identity=33.974358974359, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367378, Length=136, Percent_Identity=36.7647058823529, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787690, Length=154, Percent_Identity=33.7662337662338, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788194, Length=144, Percent_Identity=34.0277777777778, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789453, Length=86, Percent_Identity=41.8604651162791, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 53218; Mature: 53218

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVETKEISELTRSNRIAMLSHISTVTVMVFFMIWESVRGQLSPVYMTIATVVGVIPLIG
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EVICWKSNTEHAMIKHLVSYGFALFYTICLFTSPTNLIYVFVIPMIFVVTIYSDTRYLLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
INTGTILESIIVVVIGATKGGFGYHGIEAAVVQIVVMIMVGANSVLTTKVIRENTRKRFT
EECHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVAQAKAEAENLLERNEELDQQISGNIADINVRFEKLTAASKTTTEAMQEVSAGATDTAE
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHH
HVQNQLEQTHAIQDKVDEVATAVEEIGNSMTLTLKALAEGKQDIEHLASEVEASVDNGTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHHHCCCCHH
VTEKLENLNQYMDEMNSIVELIGGITNQTSLLALNASIEAARAGEAGRGFSVVATEISGM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHH
ATRTKEATVHITELISNVSNAIMEVVGVVSNMIDGINEEKTGASNAEESFESIEDNTRAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
QKNADTLSRSISELQNANKEIIDSIQTISAISQQVSAHAGETMQAEEENLNVMQDVSAIM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHH
QKLATLATH
HHHHHHHCC
>Mature Secondary Structure
MMVETKEISELTRSNRIAMLSHISTVTVMVFFMIWESVRGQLSPVYMTIATVVGVIPLIG
CCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
EVICWKSNTEHAMIKHLVSYGFALFYTICLFTSPTNLIYVFVIPMIFVVTIYSDTRYLLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE
INTGTILESIIVVVIGATKGGFGYHGIEAAVVQIVVMIMVGANSVLTTKVIRENTRKRFT
EECHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
EVAQAKAEAENLLERNEELDQQISGNIADINVRFEKLTAASKTTTEAMQEVSAGATDTAE
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHH
HVQNQLEQTHAIQDKVDEVATAVEEIGNSMTLTLKALAEGKQDIEHLASEVEASVDNGTE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHHHHHHHHCCCCHH
VTEKLENLNQYMDEMNSIVELIGGITNQTSLLALNASIEAARAGEAGRGFSVVATEISGM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHCCCCCCCHHHHHHHHHHH
ATRTKEATVHITELISNVSNAIMEVVGVVSNMIDGINEEKTGASNAEESFESIEDNTRAI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
QKNADTLSRSISELQNANKEIIDSIQTISAISQQVSAHAGETMQAEEENLNVMQDVSAIM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHH
QKLATLATH
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]