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The map label for this gene is cat2 [H]

Identifier: 238925420

GI number: 238925420

Start: 2938652

End: 2939992

Strand: Direct

Name: cat2 [H]

Synonym: EUBREC_3075

Alternate gene names: 238925420

Gene position: 2938652-2939992 (Clockwise)

Preceding gene: 238925419

Following gene: 238925443

Centisome position: 85.19

GC content: 47.28

Gene sequence:

>1341_bases
ATGAGCTTTTTAGAAGAGTACAAGCAGAAACTTGTCTCAGCAGATGAGGCAGTAAAGATTGTCAAATCAGGCGACTGGGT
TGACTACGGCTGGTGCACAGGCACACCTGATGCCCTCGACAAGGCACTTGCCAGAAGAACTGATGAACTTAAGGATGTCA
ATGTACGTGGTGGTATTTTGCTTAAGCCACTTGCCATTTTCGAGCGTGAGGATGCCGGCGAGCACTTCACATGGAACTCA
TGGCATATGGGCGGTTATGAGAGAAAGCTTATCAAGAGAGGCTGTTCTTTCTACTCACCAATCCGTTACTCAGAGCTTCC
TCGTTATTATAGAGATTCAACAACACCTGACGATGTCGCTATGTTCCAGGTTGCACCGATGGATTCACACGGATACTTCA
ACTTTGGTCCTAACGCATCTCACCTCGGTGCTGTATGCGAGACTTCAAAGAAAATCATCGTTGAGGTCAATGAAAACATG
CCTCGCTGTCACGGCGGTTCAGAAGCCAATGTACATATTTCACAGGTTTCTTACATTGTTGAGGGTGACAACCCTGCAAT
CGGAGAGCTTGGTGCCGGTGGTCCTGCAACAGATGTAGACAAGAAGGTTGCAGAGCTTATCGTTGACCAGATTCCAAACG
GTGCCTGTCTCCAGCTCGGTATCGGCGGAATGCCAAACGCAGTAGGCTCACTCATCGCTGAGTCAGACCTCAAGGATCTC
GGTGTCCACACAGAGATGTACGTTGACGCATTCGTTGACATCGCAAAGGCCGGAAAAATCACAGGAGCAAAGAAAAACAT
CGACCGTTATCGTCAGGCTTACGGCTTCGGTGCCGGAACCAAGAAGATGTACGATTACCTCGATGAGAATCCTGAGCTCA
TGAGTGCCCCGGTAAGCTACACAAATGATATCAAAAATATTGCCGCACTTGACAATTTCATCTCAATCAATAACTGTGTA
GACCTTGACCTCTTCGGACAGATCAGCTCAGAGACCTCAGGCACAAAGCACATCAGCGGTGCCGGCGGACAGCTTGATTT
CGTTCTCGGTGCTTATATGTCAAACGGTGGAAAGAGCTTTATCTGCTGCTCTTCAACTTTCACCGACAAGCAGGGCGTAG
TTCACTCACGTATCCGTCCTACTCTTGTAGAGGGTTCTGTCGTTACTGACACAAGAGCCAATACTCACTATATCGTTACA
GAGTATGGTATGGTAAATGTAAAGGGTCTTTCTACATGGCAGAAAGCAGAGGCAATCATCTCAGTTGCTCATCCTGATTT
CCGTGATGAGCTCATCAAAGAGGCTGAGAAGATGCACATTTGGAAAAGATCTAACAAATAA

Upstream 100 bases:

>100_bases
TAAAATCCTCTCTAAAGTGATAATATAGAGATTATAGGGTTTGTTATTTTTTTAACGTAGCATTTTGCTACTATCATTTT
AGGTATCTAAGGAGGATTTT

Downstream 100 bases:

>100_bases
TTATCTTTGGATATAATTTTTACAATAAAAGCGGTTTCAGGATGCAATGTCCTGAAACCGCTTTTGTGTTATTAATCCGT
CCCACAAACTATATTTTCAA

Product: 4-hydroxybutyrate coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGILLKPLAIFEREDAGEHFTWNS
WHMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTPDDVAMFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENM
PRCHGGSEANVHISQVSYIVEGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDL
GVHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSYTNDIKNIAALDNFISINNCV
DLDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSFICCSSTFTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIVT
EYGMVNVKGLSTWQKAEAIISVAHPDFRDELIKEAEKMHIWKRSNK

Sequences:

>Translated_446_residues
MSFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGILLKPLAIFEREDAGEHFTWNS
WHMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTPDDVAMFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENM
PRCHGGSEANVHISQVSYIVEGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDL
GVHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSYTNDIKNIAALDNFISINNCV
DLDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSFICCSSTFTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIVT
EYGMVNVKGLSTWQKAEAIISVAHPDFRDELIKEAEKMHIWKRSNK
>Mature_445_residues
SFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGILLKPLAIFEREDAGEHFTWNSW
HMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTPDDVAMFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENMP
RCHGGSEANVHISQVSYIVEGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDLG
VHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSYTNDIKNIAALDNFISINNCVD
LDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSFICCSSTFTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIVTE
YGMVNVKGLSTWQKAEAIISVAHPDFRDELIKEAEKMHIWKRSNK

Specific function: Unknown

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=480, Percent_Identity=23.5416666666667, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17538151, Length=434, Percent_Identity=35.4838709677419, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32563853, Length=432, Percent_Identity=33.7962962962963, Blast_Score=224, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6319456, Length=500, Percent_Identity=24.2, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358615, Length=441, Percent_Identity=33.5600907029478, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro [H]

EC number: NA

Molecular weight: Translated: 48956; Mature: 48825

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGIL
CCHHHHHHHHHHCHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
LKPLAIFEREDAGEHFTWNSWHMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTPDDVA
ECHHHHEECCCCCCCCCCCCEECCCHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCEE
MFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENMPRCHGGSEANVHISQVSYIV
EEEEECCCCCCCEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEE
EGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDL
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHHH
GVHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSY
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCH
TNDIKNIAALDNFISINNCVDLDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSF
HHHHHHHHHHHHHEECCCEECCHHHCCCCCCCCCCCEECCCCCEEHHHHHHHHCCCCCEE
ICCSSTFTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIVTEYGMVNVKGLSTWQKAEAII
EEECCCCCCCCCCHHHCCCCEEECCCEEECCCCCCEEEEEECCEEEECCCCHHHHHHHHE
SVAHPDFRDELIKEAEKMHIWKRSNK
EECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFLEEYKQKLVSADEAVKIVKSGDWVDYGWCTGTPDALDKALARRTDELKDVNVRGGIL
CHHHHHHHHHHCHHHHHHHEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCEE
LKPLAIFEREDAGEHFTWNSWHMGGYERKLIKRGCSFYSPIRYSELPRYYRDSTTPDDVA
ECHHHHEECCCCCCCCCCCCEECCCHHHHHHHHCCCCCCCCCHHHCCHHHCCCCCCCCEE
MFQVAPMDSHGYFNFGPNASHLGAVCETSKKIIVEVNENMPRCHGGSEANVHISQVSYIV
EEEEECCCCCCCEECCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEEE
EGDNPAIGELGAGGPATDVDKKVAELIVDQIPNGACLQLGIGGMPNAVGSLIAESDLKDL
ECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCCHHHH
GVHTEMYVDAFVDIAKAGKITGAKKNIDRYRQAYGFGAGTKKMYDYLDENPELMSAPVSY
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEECCCCH
TNDIKNIAALDNFISINNCVDLDLFGQISSETSGTKHISGAGGQLDFVLGAYMSNGGKSF
HHHHHHHHHHHHHEECCCEECCHHHCCCCCCCCCCCEECCCCCEEHHHHHHHHCCCCCEE
ICCSSTFTDKQGVVHSRIRPTLVEGSVVTDTRANTHYIVTEYGMVNVKGLSTWQKAEAII
EEECCCCCCCCCCHHHCCCCEEECCCEEECCCCCCEEEEEECCEEEECCCCHHHHHHHHE
SVAHPDFRDELIKEAEKMHIWKRSNK
EECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]