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The map label for this gene is siaP [H]

Identifier: 238925183

GI number: 238925183

Start: 2719146

End: 2720249

Strand: Reverse

Name: siaP [H]

Synonym: EUBREC_2837

Alternate gene names: 238925183

Gene position: 2720249-2719146 (Counterclockwise)

Preceding gene: 238925184

Following gene: 238925182

Centisome position: 78.85

GC content: 46.74

Gene sequence:

>1104_bases
ATGAGTAGATTTGGCTTGTTTTTATGTAAAAAAGCTGGTAAATATAATAAACCGCGTAAATCGTATAGCAAATATAGATT
GTGGCGAAGAGCAGCCGCCGTCATGATGATACTTTCGCTTACAGCAGGACTTGCCGCGTGCGGTGGCTCTGCTGGTGAAG
GCTCGCAGGCTGCAGCTAAGGCTGCCGGGGTACAGCGTTACGCATGGCCTCTCGGCAGTTCAAGTCCTGAGGACACCGTG
ACACAGATATATGCAGAGAAATTTGCCGATGAAGTGGACAGATTAAGCGATGGCAAGATGAAAATCAGTGTGTATCCAAA
CAGTGTACTGGGCGGAGACAGAGAGCTTCTCGAGTCATGCAAGGATGGAGATATACCTTTTGTAGTGCAGAACACTGCGC
CCCAGGTAACTTTCATGAAGGATACTGCAGTATTTGATATGCCGGCACTCTTTGACAGCATTGATGAGGTGCGTGAGCAT
GTGGACAATCCAAGGTTTATGAAGCTCATGCAGCAGGTCTACAATGACGGCGGCTACGAGCTTTTGGGATATGCAGACCA
GGGATTCCGTGTTATGACAACAAACAAAAAGATAGAAAGCCTTGCTGATTTTAAGGGTCAGAAAATCCGTACAATGGAAA
ACTCTTATCATATGGCATACTGGAAGGCGCTCGGAGCAAGCCCGACACCTATGACTTTCTCGGAGGTGTATATCGGCTTA
CAGCAGGGCACCATAGATGCGCAGGAAAACCCATACGAGGTAATCGTATCCAATAAGCTCTATGAGCAGCAGGATTATGT
AGTGGAGACAAATCATCTGCCACATCTGATATCGCTCATAGTAAGCGAGGAGTTCATGAAAGGACTGACAGATGAGCAGC
AGCAGATTATCCGTGAGGCAGCCGAGACAGCGAAACAGTACGCCAGAGAGCAGTCTGACGAGCGTATTGCCTCAAAGATA
AAGACTATCGAGGACAGTGGCACACAAATCATCACTTTAAGCGATGAAGTGCATGAGCAGATTCGCAAGGAGTGTCAGCC
GATATATGAATCGATTGAGAAAAATGTGTCGTCTGATATTGTGGATGCATATCTGACACAATAA

Upstream 100 bases:

>100_bases
AATATTAACTATTCGGTACAGAAATATGTAATAACAGGTATAAGCAGATTTAATGATGATTGTAGGATATTTAGGCACAC
AGTTGTAATTGGAGAAAAAT

Downstream 100 bases:

>100_bases
CACTTTAAAGCATTAAAATATTTTGCTTGATAAATTGGTAAAGTCTTGTTATACTATGACTAAGAAATTTGTGGTTATCA
AAAATGCGAAATACTATAAC

Product: hypothetical protein

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSRFGLFLCKKAGKYNKPRKSYSKYRLWRRAAAVMMILSLTAGLAACGGSAGEGSQAAAKAAGVQRYAWPLGSSSPEDTV
TQIYAEKFADEVDRLSDGKMKISVYPNSVLGGDRELLESCKDGDIPFVVQNTAPQVTFMKDTAVFDMPALFDSIDEVREH
VDNPRFMKLMQQVYNDGGYELLGYADQGFRVMTTNKKIESLADFKGQKIRTMENSYHMAYWKALGASPTPMTFSEVYIGL
QQGTIDAQENPYEVIVSNKLYEQQDYVVETNHLPHLISLIVSEEFMKGLTDEQQQIIREAAETAKQYAREQSDERIASKI
KTIEDSGTQIITLSDEVHEQIRKECQPIYESIEKNVSSDIVDAYLTQ

Sequences:

>Translated_367_residues
MSRFGLFLCKKAGKYNKPRKSYSKYRLWRRAAAVMMILSLTAGLAACGGSAGEGSQAAAKAAGVQRYAWPLGSSSPEDTV
TQIYAEKFADEVDRLSDGKMKISVYPNSVLGGDRELLESCKDGDIPFVVQNTAPQVTFMKDTAVFDMPALFDSIDEVREH
VDNPRFMKLMQQVYNDGGYELLGYADQGFRVMTTNKKIESLADFKGQKIRTMENSYHMAYWKALGASPTPMTFSEVYIGL
QQGTIDAQENPYEVIVSNKLYEQQDYVVETNHLPHLISLIVSEEFMKGLTDEQQQIIREAAETAKQYAREQSDERIASKI
KTIEDSGTQIITLSDEVHEQIRKECQPIYESIEKNVSSDIVDAYLTQ
>Mature_366_residues
SRFGLFLCKKAGKYNKPRKSYSKYRLWRRAAAVMMILSLTAGLAACGGSAGEGSQAAAKAAGVQRYAWPLGSSSPEDTVT
QIYAEKFADEVDRLSDGKMKISVYPNSVLGGDRELLESCKDGDIPFVVQNTAPQVTFMKDTAVFDMPALFDSIDEVREHV
DNPRFMKLMQQVYNDGGYELLGYADQGFRVMTTNKKIESLADFKGQKIRTMENSYHMAYWKALGASPTPMTFSEVYIGLQ
QGTIDAQENPYEVIVSNKLYEQQDYVVETNHLPHLISLIVSEEFMKGLTDEQQQIIREAAETAKQYAREQSDERIASKIK
TIEDSGTQIITLSDEVHEQIRKECQPIYESIEKNVSSDIVDAYLTQ

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=315, Percent_Identity=28.2539682539683, Blast_Score=129, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 41230; Mature: 41099

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFGLFLCKKAGKYNKPRKSYSKYRLWRRAAAVMMILSLTAGLAACGGSAGEGSQAAAK
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAGVQRYAWPLGSSSPEDTVTQIYAEKFADEVDRLSDGKMKISVYPNSVLGGDRELLESC
HHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCCHHHHHHC
KDGDIPFVVQNTAPQVTFMKDTAVFDMPALFDSIDEVREHVDNPRFMKLMQQVYNDGGYE
CCCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCE
LLGYADQGFRVMTTNKKIESLADFKGQKIRTMENSYHMAYWKALGASPTPMTFSEVYIGL
EEEECCCCCEEEECCHHHHHHHHCCCCEEHHHHCCHHHHHHHHHCCCCCCCCHHHHHEEH
QQGTIDAQENPYEVIVSNKLYEQQDYVVETNHLPHLISLIVSEEFMKGLTDEQQQIIREA
HCCCCCCCCCCCEEEECCHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AETAKQYAREQSDERIASKIKTIEDSGTQIITLSDEVHEQIRKECQPIYESIEKNVSSDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAYLTQ
HHHHHCC
>Mature Secondary Structure 
SRFGLFLCKKAGKYNKPRKSYSKYRLWRRAAAVMMILSLTAGLAACGGSAGEGSQAAAK
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AAGVQRYAWPLGSSSPEDTVTQIYAEKFADEVDRLSDGKMKISVYPNSVLGGDRELLESC
HHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHCCCCHHHHHHC
KDGDIPFVVQNTAPQVTFMKDTAVFDMPALFDSIDEVREHVDNPRFMKLMQQVYNDGGYE
CCCCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCE
LLGYADQGFRVMTTNKKIESLADFKGQKIRTMENSYHMAYWKALGASPTPMTFSEVYIGL
EEEECCCCCEEEECCHHHHHHHHCCCCEEHHHHCCHHHHHHHHHCCCCCCCCHHHHHEEH
QQGTIDAQENPYEVIVSNKLYEQQDYVVETNHLPHLISLIVSEEFMKGLTDEQQQIIREA
HCCCCCCCCCCCEEEECCHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AETAKQYAREQSDERIASKIKTIEDSGTQIITLSDEVHEQIRKECQPIYESIEKNVSSDI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
VDAYLTQ
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA