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The map label for this gene is hisK [H]

Identifier: 238925148

GI number: 238925148

Start: 2677946

End: 2678716

Strand: Reverse

Name: hisK [H]

Synonym: EUBREC_2801

Alternate gene names: 238925148

Gene position: 2678716-2677946 (Counterclockwise)

Preceding gene: 238925154

Following gene: 238925147

Centisome position: 77.65

GC content: 46.3

Gene sequence:

>771_bases
ATGACGGGATTTTTAAAGGCAAACTACCATACGCACACCTATAGGTGCCAGCATGCATATGGCAGCGAGCGCGAATATAT
AGAGGCGGCTATCAGAATGGGTATCGCAGAGCTTGGTTTTTCAGACCATGTGCCGTGCCCCTTTAAGGATGGCTATGTGT
CGGGCATCCGGATGACGATGGAGCAGGCACCGGAGTATGTGTATGCCATCAGGGAGCTTGGGAAGGAGTATGCATCCGAC
ATAAAGCTCTATGTCGGCTTTGAGGCGGAGTACATACCGGAGTTTTTCAAGGAGCAGAAGGCTATGTTTGACAGGCTTGG
CTGTGATTACATGATAATGGGCCAGCATTTTATGAAATCAGAGCAGACAGGCCCGTATACAGGCACACCGACAGATGATG
AGAGCCGTATACGCGAGTATGTGGATACTGTTATAGAGGGAATGAAAACAGGCATGTACAGCTATTTAGCACATCCTGAT
TTAATAAATTATCAGGGACTTGATTCCGTCTACGAATGGGAGATGACGAGGATGTGCAAGGCACTTAAGGAGCTTGACAT
ACCGCTTGAGATAAACATGCTTGGTATCAGTGCAGGAAAGCACTATCCGACAGAGCGCTTCTGGTGTATACCGCATGACA
TCGGCAACAAAGTGATACTTGGGCTTGATGCACATACAGTGGACAATATATGTGATGTGGAAAGCTATGAAAAGGCACTT
GATATAGTCAGAAAATATGACCTGAATCTTATTGACCGGATTGAGATATAG

Upstream 100 bases:

>100_bases
GATTGTAATAAAGTACAAAAAGTGATAAAATTGATTTAATTGTAGTATTTGAATAGCTGTTTGAACAGCAATAAGAGATA
GATTTTTGGAGCTTTAAGTA

Downstream 100 bases:

>100_bases
TTACTTACAAAATATCAAATACCAAAAGTGAGGAATGCTATGATTATTACAGAAGAAAAATATAATGAGGAATTAACAAG
ATATGTTTTGCCTTTTATCA

Product: histidinol phosphate phosphatase family protein

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTGFLKANYHTHTYRCQHAYGSEREYIEAAIRMGIAELGFSDHVPCPFKDGYVSGIRMTMEQAPEYVYAIRELGKEYASD
IKLYVGFEAEYIPEFFKEQKAMFDRLGCDYMIMGQHFMKSEQTGPYTGTPTDDESRIREYVDTVIEGMKTGMYSYLAHPD
LINYQGLDSVYEWEMTRMCKALKELDIPLEINMLGISAGKHYPTERFWCIPHDIGNKVILGLDAHTVDNICDVESYEKAL
DIVRKYDLNLIDRIEI

Sequences:

>Translated_256_residues
MTGFLKANYHTHTYRCQHAYGSEREYIEAAIRMGIAELGFSDHVPCPFKDGYVSGIRMTMEQAPEYVYAIRELGKEYASD
IKLYVGFEAEYIPEFFKEQKAMFDRLGCDYMIMGQHFMKSEQTGPYTGTPTDDESRIREYVDTVIEGMKTGMYSYLAHPD
LINYQGLDSVYEWEMTRMCKALKELDIPLEINMLGISAGKHYPTERFWCIPHDIGNKVILGLDAHTVDNICDVESYEKAL
DIVRKYDLNLIDRIEI
>Mature_255_residues
TGFLKANYHTHTYRCQHAYGSEREYIEAAIRMGIAELGFSDHVPCPFKDGYVSGIRMTMEQAPEYVYAIRELGKEYASDI
KLYVGFEAEYIPEFFKEQKAMFDRLGCDYMIMGQHFMKSEQTGPYTGTPTDDESRIREYVDTVIEGMKTGMYSYLAHPDL
INYQGLDSVYEWEMTRMCKALKELDIPLEINMLGISAGKHYPTERFWCIPHDIGNKVILGLDAHTVDNICDVESYEKALD
IVRKYDLNLIDRIEI

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 29640; Mature: 29509

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFLKANYHTHTYRCQHAYGSEREYIEAAIRMGIAELGFSDHVPCPFKDGYVSGIRMTM
CCCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
EQAPEYVYAIRELGKEYASDIKLYVGFEAEYIPEFFKEQKAMFDRLGCDYMIMGQHFMKS
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHC
EQTGPYTGTPTDDESRIREYVDTVIEGMKTGMYSYLAHPDLINYQGLDSVYEWEMTRMCK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ALKELDIPLEINMLGISAGKHYPTERFWCIPHDIGNKVILGLDAHTVDNICDVESYEKAL
HHHHCCCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
DIVRKYDLNLIDRIEI
HHHHHHCCCHHHHCCC
>Mature Secondary Structure 
TGFLKANYHTHTYRCQHAYGSEREYIEAAIRMGIAELGFSDHVPCPFKDGYVSGIRMTM
CCEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
EQAPEYVYAIRELGKEYASDIKLYVGFEAEYIPEFFKEQKAMFDRLGCDYMIMGQHFMKS
HHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEECHHHHHC
EQTGPYTGTPTDDESRIREYVDTVIEGMKTGMYSYLAHPDLINYQGLDSVYEWEMTRMCK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
ALKELDIPLEINMLGISAGKHYPTERFWCIPHDIGNKVILGLDAHTVDNICDVESYEKAL
HHHHCCCCEEEEEEEEECCCCCCCCEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
DIVRKYDLNLIDRIEI
HHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]