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The map label for this gene is yihQ [H]

Identifier: 238924941

GI number: 238924941

Start: 2465081

End: 2467087

Strand: Reverse

Name: yihQ [H]

Synonym: EUBREC_2592

Alternate gene names: 238924941

Gene position: 2467087-2465081 (Counterclockwise)

Preceding gene: 238924942

Following gene: 238924940

Centisome position: 71.52

GC content: 41.75

Gene sequence:

>2007_bases
ATGCAGATTAAAGTAAATGATAATGAATTTCAGCTTTTTGTGGGAGAAAAAAGGATTCTGGAGCATAGCAAAGAAAGACC
GATGATTTATGTCGGAGTAGGACAGGAAGATGTTGATATGTACAGAGGTAACTTCAAGATAACAGATTATGTTACCGAGC
GTTTTCCACTAAAGCTCACAGATGTGATTCAGACAGCTGATACAGTCAGACTATGCTTTGAAAGCTATATCATTGCGAAA
ATTAAATGTGACGAAAATCTGTGTACCATTGATTTTGAACAAAAGGATGACAGGATTAACCGATTCTGGTTTAGGGTAGC
CGCGGATAAAGAGGAAAAATGCTATGGCTGCGGTGAGCAGATGTCTTACTTTAATCTGCGTGGAAGAAATTTTCCTATCT
GGACATCTGAACCAGGTGTCGGACGTGATAAGACAACTTACGTTACATGGCGTTCGGATGTAGAAAATAAAGCTGGAGGA
GACTATTACAACACAAATTATCCACAGCCAACCTTTGTTTCCACAAATAAATATTATCTGCATGTGGATTCAACAGCATA
TGCTGATTTTGATTTCAGAAATGACAGCTTTCATGAGCTGCAGATATGGGAGGTGCCTAAGCAGATCCGCATAGAGTGTG
CTGATACATATCTCAAACTGCTTGAGAGAATCACAACATATTTTGGAAGACAGCCAAAGCTCCCGGATTGGGTATACAAT
GGTCTCATAATCGGTGTTCAGGGTGGAAATGAAAGGTCATTTGGATTGCTTGATAAGACCCTTGATAGGAACATCAAGGT
AGCTGGCATATGGTGCCAGGATTGGTGCGGAAAGAGAGTGACATCATTCGGAAAGAGACTCCAATGGGACTGGAAATACC
ACAAGGAAATGTATCCGGATCTGCCAAAGAAGATTAAAGAGATAAATGCAAAGGGCATAAAATTTTTGGGATATGTTAAT
CCATATCTGGTAAATGATGGTGAGCTCTATAAGGAAGGCAAGGAAAAAGGCTATTTTGCAACAAAGGCAGATGGCAGTGA
TTATCTCGTGGATTTTGGTGAATTTTATTGTGGAGTTGTGGATCTCACAAATCCGGAGGCATTCGAGTGGTTTAAGGATA
TTATTAAAGAATACACACTTGGTATAGGCATTGATGGCTGGATGGCAGACTTTGGAGAGTATCTGCCTACAGATGATATA
TGCTTATACAGCGGTAAATCACCTATGATTGAGCACAATCACTGGCCGGTGCTATGGGCAAAGTGTAACTATGAGGCAGT
AAAAGAGTCAGGAAAGCTTGGAGATGTGGTTTACTTCATGCGTGCCGGAGGTGCAGGAAGCCAGAAATACTGCACATTGC
TGTGGGCCGGCGATCAGTCTGTTGACTTTACAATACATGATGGACTCGCATCTGTTATCTGCGGAGCACTTAGTGCAGGA
ATGATGGGATGTGGGCTCACGCATAGTGATATTGGAGGCTATACATCGCTTTTTGATAATACTCGTACAAAGGAGCTGTT
TCTCAGATGGGCTGAGATGGCGATGTTTACACCATTTATGAGGACACATGAGGGAAACAGACCGGATACCAATTTTCAGT
ATTACGATGATGAGGATACCATGGAGCGGCTGGCGAGACTCGTTGATGTATACACGATGCTTGCACCGTATACAAAGACA
CTTGTTGAAGAGAATGCAGACAGTGGACATCCGGTGCAAAGACCTTTGTTCATGCATTATGAGTCTGATGCGAAAGCTTA
TGACATACAGTATGAGTATCTTTTTGGAAGAGATATGCTGATAGCACCTGTTTATGAGCAGGATAAGCATGAATGGGATG
TGTATCTGCCACAGGATGAATGGGTACATTTGTGGACAGGCGAAGAGTATCACGGCGGAGAAATAACAGTATCAGCCGAG
CTTGGCTATACACCTGCCTTCTACAGAAAAAATAGTGAGTTTGCTGATATATTTGAAGAAATCAGAGAAAAATATGGAGT
CAAATAA

Upstream 100 bases:

>100_bases
AAGAATTGCTATTGTAACAGCAATATTTGTGATTGAGACAATTGTTCTGATTGTGAAAGAGATGAACAAGCGTAAAAAGA
CAGCTTAGGGAGGTTATTAA

Downstream 100 bases:

>100_bases
ATGAACACTGTTTTATTTTACATAATAATTTTTCTGACAAATGTGATTCAGGGCATTACAGGCTTTGCGGGGACCATCCT
CGCAATGCCTCCTAGCCTAA

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MQIKVNDNEFQLFVGEKRILEHSKERPMIYVGVGQEDVDMYRGNFKITDYVTERFPLKLTDVIQTADTVRLCFESYIIAK
IKCDENLCTIDFEQKDDRINRFWFRVAADKEEKCYGCGEQMSYFNLRGRNFPIWTSEPGVGRDKTTYVTWRSDVENKAGG
DYYNTNYPQPTFVSTNKYYLHVDSTAYADFDFRNDSFHELQIWEVPKQIRIECADTYLKLLERITTYFGRQPKLPDWVYN
GLIIGVQGGNERSFGLLDKTLDRNIKVAGIWCQDWCGKRVTSFGKRLQWDWKYHKEMYPDLPKKIKEINAKGIKFLGYVN
PYLVNDGELYKEGKEKGYFATKADGSDYLVDFGEFYCGVVDLTNPEAFEWFKDIIKEYTLGIGIDGWMADFGEYLPTDDI
CLYSGKSPMIEHNHWPVLWAKCNYEAVKESGKLGDVVYFMRAGGAGSQKYCTLLWAGDQSVDFTIHDGLASVICGALSAG
MMGCGLTHSDIGGYTSLFDNTRTKELFLRWAEMAMFTPFMRTHEGNRPDTNFQYYDDEDTMERLARLVDVYTMLAPYTKT
LVEENADSGHPVQRPLFMHYESDAKAYDIQYEYLFGRDMLIAPVYEQDKHEWDVYLPQDEWVHLWTGEEYHGGEITVSAE
LGYTPAFYRKNSEFADIFEEIREKYGVK

Sequences:

>Translated_668_residues
MQIKVNDNEFQLFVGEKRILEHSKERPMIYVGVGQEDVDMYRGNFKITDYVTERFPLKLTDVIQTADTVRLCFESYIIAK
IKCDENLCTIDFEQKDDRINRFWFRVAADKEEKCYGCGEQMSYFNLRGRNFPIWTSEPGVGRDKTTYVTWRSDVENKAGG
DYYNTNYPQPTFVSTNKYYLHVDSTAYADFDFRNDSFHELQIWEVPKQIRIECADTYLKLLERITTYFGRQPKLPDWVYN
GLIIGVQGGNERSFGLLDKTLDRNIKVAGIWCQDWCGKRVTSFGKRLQWDWKYHKEMYPDLPKKIKEINAKGIKFLGYVN
PYLVNDGELYKEGKEKGYFATKADGSDYLVDFGEFYCGVVDLTNPEAFEWFKDIIKEYTLGIGIDGWMADFGEYLPTDDI
CLYSGKSPMIEHNHWPVLWAKCNYEAVKESGKLGDVVYFMRAGGAGSQKYCTLLWAGDQSVDFTIHDGLASVICGALSAG
MMGCGLTHSDIGGYTSLFDNTRTKELFLRWAEMAMFTPFMRTHEGNRPDTNFQYYDDEDTMERLARLVDVYTMLAPYTKT
LVEENADSGHPVQRPLFMHYESDAKAYDIQYEYLFGRDMLIAPVYEQDKHEWDVYLPQDEWVHLWTGEEYHGGEITVSAE
LGYTPAFYRKNSEFADIFEEIREKYGVK
>Mature_668_residues
MQIKVNDNEFQLFVGEKRILEHSKERPMIYVGVGQEDVDMYRGNFKITDYVTERFPLKLTDVIQTADTVRLCFESYIIAK
IKCDENLCTIDFEQKDDRINRFWFRVAADKEEKCYGCGEQMSYFNLRGRNFPIWTSEPGVGRDKTTYVTWRSDVENKAGG
DYYNTNYPQPTFVSTNKYYLHVDSTAYADFDFRNDSFHELQIWEVPKQIRIECADTYLKLLERITTYFGRQPKLPDWVYN
GLIIGVQGGNERSFGLLDKTLDRNIKVAGIWCQDWCGKRVTSFGKRLQWDWKYHKEMYPDLPKKIKEINAKGIKFLGYVN
PYLVNDGELYKEGKEKGYFATKADGSDYLVDFGEFYCGVVDLTNPEAFEWFKDIIKEYTLGIGIDGWMADFGEYLPTDDI
CLYSGKSPMIEHNHWPVLWAKCNYEAVKESGKLGDVVYFMRAGGAGSQKYCTLLWAGDQSVDFTIHDGLASVICGALSAG
MMGCGLTHSDIGGYTSLFDNTRTKELFLRWAEMAMFTPFMRTHEGNRPDTNFQYYDDEDTMERLARLVDVYTMLAPYTKT
LVEENADSGHPVQRPLFMHYESDAKAYDIQYEYLFGRDMLIAPVYEQDKHEWDVYLPQDEWVHLWTGEEYHGGEITVSAE
LGYTPAFYRKNSEFADIFEEIREKYGVK

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI119393895, Length=375, Percent_Identity=25.0666666666667, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI119393893, Length=375, Percent_Identity=25.0666666666667, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI119393891, Length=375, Percent_Identity=25.0666666666667, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI153791946, Length=342, Percent_Identity=26.0233918128655, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI88900491, Length=392, Percent_Identity=25.765306122449, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI38202257, Length=392, Percent_Identity=25.765306122449, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI66346737, Length=387, Percent_Identity=25.0645994832041, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI221316699, Length=403, Percent_Identity=23.8213399503722, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI310115361, Length=221, Percent_Identity=28.9592760180996, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI2367323, Length=667, Percent_Identity=52.9235382308846, Blast_Score=762, Evalue=0.0,
Organism=Escherichia coli, GI2367256, Length=554, Percent_Identity=24.7292418772563, Blast_Score=169, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17560798, Length=399, Percent_Identity=25.062656641604, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17560800, Length=399, Percent_Identity=25.062656641604, Blast_Score=116, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71991189, Length=365, Percent_Identity=25.7534246575342, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985706, Length=236, Percent_Identity=28.3898305084746, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563849, Length=272, Percent_Identity=28.6764705882353, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319706, Length=244, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650054, Length=364, Percent_Identity=25.8241758241758, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24643749, Length=347, Percent_Identity=23.9193083573487, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643753, Length=347, Percent_Identity=23.9193083573487, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643751, Length=347, Percent_Identity=23.9193083573487, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643746, Length=347, Percent_Identity=23.9193083573487, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357605, Length=347, Percent_Identity=23.9193083573487, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 77722; Mature: 77722

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIKVNDNEFQLFVGEKRILEHSKERPMIYVGVGQEDVDMYRGNFKITDYVTERFPLKLT
CEEEEECCEEEEEECCHHHHHCCCCCCEEEEECCCHHHHHHCCCEEEEEEHHCCCCEEHH
DVIQTADTVRLCFESYIIAKIKCDENLCTIDFEQKDDRINRFWFRVAADKEEKCYGCGEQ
HHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCCCCHHCCCCCC
MSYFNLRGRNFPIWTSEPGVGRDKTTYVTWRSDVENKAGGDYYNTNYPQPTFVSTNKYYL
CEEEEECCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEE
HVDSTAYADFDFRNDSFHELQIWEVPKQIRIECADTYLKLLERITTYFGRQPKLPDWVYN
EECCCEEEEEECCCCCCEEEEEEECCHHHEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GLIIGVQGGNERSFGLLDKTLDRNIKVAGIWCQDWCGKRVTSFGKRLQWDWKYHKEMYPD
CEEEEEECCCCCCCCHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHEECCCHHHHHHCCC
LPKKIKEINAKGIKFLGYVNPYLVNDGELYKEGKEKGYFATKADGSDYLVDFGEFYCGVV
HHHHHHHCCCCCEEEEECCCCEEECCCHHHHCCCCCCEEEEECCCCCCEEECCCCEEEEE
DLTNPEAFEWFKDIIKEYTLGIGIDGWMADFGEYLPTDDICLYSGKSPMIEHNHWPVLWA
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEECCCCEEEEE
KCNYEAVKESGKLGDVVYFMRAGGAGSQKYCTLLWAGDQSVDFTIHDGLASVICGALSAG
ECCHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHH
MMGCGLTHSDIGGYTSLFDNTRTKELFLRWAEMAMFTPFMRTHEGNRPDTNFQYYDDEDT
HHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHH
MERLARLVDVYTMLAPYTKTLVEENADSGHPVQRPLFMHYESDAKAYDIQYEYLFGRDML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCEE
IAPVYEQDKHEWDVYLPQDEWVHLWTGEEYHGGEITVSAELGYTPAFYRKNSEFADIFEE
EEECCCCCCCCEEEECCCCCEEEEECCCEECCCEEEEEEECCCCCHHHCCCCHHHHHHHH
IREKYGVK
HHHHHCCC
>Mature Secondary Structure
MQIKVNDNEFQLFVGEKRILEHSKERPMIYVGVGQEDVDMYRGNFKITDYVTERFPLKLT
CEEEEECCEEEEEECCHHHHHCCCCCCEEEEECCCHHHHHHCCCEEEEEEHHCCCCEEHH
DVIQTADTVRLCFESYIIAKIKCDENLCTIDFEQKDDRINRFWFRVAADKEEKCYGCGEQ
HHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCCCCHHCCCCCC
MSYFNLRGRNFPIWTSEPGVGRDKTTYVTWRSDVENKAGGDYYNTNYPQPTFVSTNKYYL
CEEEEECCCCCCEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEE
HVDSTAYADFDFRNDSFHELQIWEVPKQIRIECADTYLKLLERITTYFGRQPKLPDWVYN
EECCCEEEEEECCCCCCEEEEEEECCHHHEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHC
GLIIGVQGGNERSFGLLDKTLDRNIKVAGIWCQDWCGKRVTSFGKRLQWDWKYHKEMYPD
CEEEEEECCCCCCCCHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHEECCCHHHHHHCCC
LPKKIKEINAKGIKFLGYVNPYLVNDGELYKEGKEKGYFATKADGSDYLVDFGEFYCGVV
HHHHHHHCCCCCEEEEECCCCEEECCCHHHHCCCCCCEEEEECCCCCCEEECCCCEEEEE
DLTNPEAFEWFKDIIKEYTLGIGIDGWMADFGEYLPTDDICLYSGKSPMIEHNHWPVLWA
ECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCEECCCCEEEEE
KCNYEAVKESGKLGDVVYFMRAGGAGSQKYCTLLWAGDQSVDFTIHDGLASVICGALSAG
ECCHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHH
MMGCGLTHSDIGGYTSLFDNTRTKELFLRWAEMAMFTPFMRTHEGNRPDTNFQYYDDEDT
HHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHH
MERLARLVDVYTMLAPYTKTLVEENADSGHPVQRPLFMHYESDAKAYDIQYEYLFGRDML
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEECCCEE
IAPVYEQDKHEWDVYLPQDEWVHLWTGEEYHGGEITVSAELGYTPAFYRKNSEFADIFEE
EEECCCCCCCCEEEECCCCCEEEEECCCEECCCEEEEEEECCCCCHHHCCCCHHHHHHHH
IREKYGVK
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]