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The map label for this gene is xylB [H]

Identifier: 238924908

GI number: 238924908

Start: 2431628

End: 2433094

Strand: Reverse

Name: xylB [H]

Synonym: EUBREC_2559

Alternate gene names: 238924908

Gene position: 2433094-2431628 (Counterclockwise)

Preceding gene: 238924909

Following gene: 238924907

Centisome position: 70.53

GC content: 46.49

Gene sequence:

>1467_bases
ATGCTATATATAGGTGTGGATTTAGGCACAAGTGCAGTAAAGCTTCTGCTCATGGATGAGAGCGGAAAGGTATTAAATAT
AGTCTCAAAGGAGTATCCAATCAGCTTTCCAAAGCCGGGCTGGTCAGAGCAGAATCCATGTGACTGGTGGGAGCAGACCG
TGGCTGGGCTTATAGAGCTGACTAAAGATTTTGACAGGAGCGCTGTTGCGGGAATCAGCTTCGGAGGTCAGATGCATGGA
CTTGTCGTATTGGATGAAAACGACAATGTAATAAGACCTGCTATACTTTGGAATGACGGAAGAACACAGAAGGAGACAGA
CTATTTAAATAATGTAATAGGAAAAGAAAAGCTGTCTGAGCTCACCGGAAATATAGCGTTTGCCGGATTTACAGCGCCAA
AGATTTTATGGCTAAAAGCAAATGAACCGGAAAACTTTGCCAGAATAAAAAAGCTTATGCTGCCAAAGGATTATATTGCA
TACCGCATGACAGGTGTATTTAGTACCGATTATTCTGATGCATCGGGAATGCTTCTTCTGGATGTCAAAAATAAGTGCTG
GTCAAAGGAGATGCTTGACATATGCGATGTAAGAGAGGAGTGGCTTCCTGGGCTTTATGAGAGCAGTGAAAAGACAGGCA
CTCTGAAAGCTGATGTGGCATGTGAGCTTGGCTTTCCTAAAGACTGCATAGTTGCAGCCGGGGCAGGAGATAATGCGGCT
GCAGCTATAGGCACAGGTACAGTCGGAGCCGGAAAGTGTAACCTCTCTCTTGGAACAAGCGGCACACTTTTTATTACAAG
TGATGAGTTCAGAGTGGATTCGCACAATGCGCTTCATTCGTTTGATCATGCTGACGGCGGCTATCATCTGATGGGCTGCA
TGCTCTCGGCTGCAAGCTGCAACAACTGGTGGATGAAGGATATCCTTCATTCCGATGACTTTGTGAATGAGCAGAAGCCT
CTTGAGGAGGATGGCAGACTTGGTGAGAATCATGTGTATTTTCTGCCTTATCTGATGGGAGAGCGCTCTCCGCACAATGA
TCCGTCTGCAAGGGCAGCGTTTATTGGGATGAGCATGGATACTGACAGAGCCGACATGCTGCAGGCTGTGTTTGAGGGTG
TGGCATATGGTCTTCGAGATTCACTTGAGGTGGCAAAGAGCCTTGGTGTGGCACCAAAAAGCACAACAATCTGTGGTGGC
GGTGCAAAAAGTGTGCTTTGGAGAAAGATAGTTGCAAACGTCATGAATATGCAGGTTGACACGGTAGAGGTCGAGGAAGG
ACCGGCATACGGCGGTGCAATACTGGCTGCAGTTGCAAACGGCTGCTTTGAAAATGTGGAGGCTGCGGCAGCGGCTATTG
TGAGAAAGAAGGATACAACCATGCCAAGTCCACAGCTTGTCGAAAAATATGAGAAGGGCTATGCAAAATTTAAGCAGTTT
TATCCTGCATTAAAGGGCAAATATTAG

Upstream 100 bases:

>100_bases
CCGGCATCACTGCCATACAAGACAGAAAATCCTTTCTGTTAGTGGGGTCTGAATAGTTACGTTATCTGATGTAAACATAT
TACGTGAATGGAGAATAGAT

Downstream 100 bases:

>100_bases
TCATTTCGTAGAAAATTAAATTTGGTGTTGTAAAGTGGTGCAAATTCATGTATCTTATTATAAGGAAATGAATTTTGCAC
CACTTTTTTATGCATAATTA

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MLYIGVDLGTSAVKLLLMDESGKVLNIVSKEYPISFPKPGWSEQNPCDWWEQTVAGLIELTKDFDRSAVAGISFGGQMHG
LVVLDENDNVIRPAILWNDGRTQKETDYLNNVIGKEKLSELTGNIAFAGFTAPKILWLKANEPENFARIKKLMLPKDYIA
YRMTGVFSTDYSDASGMLLLDVKNKCWSKEMLDICDVREEWLPGLYESSEKTGTLKADVACELGFPKDCIVAAGAGDNAA
AAIGTGTVGAGKCNLSLGTSGTLFITSDEFRVDSHNALHSFDHADGGYHLMGCMLSAASCNNWWMKDILHSDDFVNEQKP
LEEDGRLGENHVYFLPYLMGERSPHNDPSARAAFIGMSMDTDRADMLQAVFEGVAYGLRDSLEVAKSLGVAPKSTTICGG
GAKSVLWRKIVANVMNMQVDTVEVEEGPAYGGAILAAVANGCFENVEAAAAAIVRKKDTTMPSPQLVEKYEKGYAKFKQF
YPALKGKY

Sequences:

>Translated_488_residues
MLYIGVDLGTSAVKLLLMDESGKVLNIVSKEYPISFPKPGWSEQNPCDWWEQTVAGLIELTKDFDRSAVAGISFGGQMHG
LVVLDENDNVIRPAILWNDGRTQKETDYLNNVIGKEKLSELTGNIAFAGFTAPKILWLKANEPENFARIKKLMLPKDYIA
YRMTGVFSTDYSDASGMLLLDVKNKCWSKEMLDICDVREEWLPGLYESSEKTGTLKADVACELGFPKDCIVAAGAGDNAA
AAIGTGTVGAGKCNLSLGTSGTLFITSDEFRVDSHNALHSFDHADGGYHLMGCMLSAASCNNWWMKDILHSDDFVNEQKP
LEEDGRLGENHVYFLPYLMGERSPHNDPSARAAFIGMSMDTDRADMLQAVFEGVAYGLRDSLEVAKSLGVAPKSTTICGG
GAKSVLWRKIVANVMNMQVDTVEVEEGPAYGGAILAAVANGCFENVEAAAAAIVRKKDTTMPSPQLVEKYEKGYAKFKQF
YPALKGKY
>Mature_488_residues
MLYIGVDLGTSAVKLLLMDESGKVLNIVSKEYPISFPKPGWSEQNPCDWWEQTVAGLIELTKDFDRSAVAGISFGGQMHG
LVVLDENDNVIRPAILWNDGRTQKETDYLNNVIGKEKLSELTGNIAFAGFTAPKILWLKANEPENFARIKKLMLPKDYIA
YRMTGVFSTDYSDASGMLLLDVKNKCWSKEMLDICDVREEWLPGLYESSEKTGTLKADVACELGFPKDCIVAAGAGDNAA
AAIGTGTVGAGKCNLSLGTSGTLFITSDEFRVDSHNALHSFDHADGGYHLMGCMLSAASCNNWWMKDILHSDDFVNEQKP
LEEDGRLGENHVYFLPYLMGERSPHNDPSARAAFIGMSMDTDRADMLQAVFEGVAYGLRDSLEVAKSLGVAPKSTTICGG
GAKSVLWRKIVANVMNMQVDTVEVEEGPAYGGAILAAVANGCFENVEAAAAAIVRKKDTTMPSPQLVEKYEKGYAKFKQF
YPALKGKY

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=446, Percent_Identity=23.7668161434978, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI4504007, Length=446, Percent_Identity=24.6636771300448, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI189409120, Length=446, Percent_Identity=24.6636771300448, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI41393575, Length=442, Percent_Identity=23.3031674208145, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI18860918, Length=535, Percent_Identity=26.1682242990654, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI88196792, Length=516, Percent_Identity=22.2868217054264, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1789987, Length=490, Percent_Identity=40.2040816326531, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1790361, Length=470, Percent_Identity=25.3191489361702, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790005, Length=491, Percent_Identity=25.2545824847251, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1789168, Length=423, Percent_Identity=26.0047281323877, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787789, Length=510, Percent_Identity=23.5294117647059, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17535599, Length=455, Percent_Identity=25.7142857142857, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17554530, Length=486, Percent_Identity=23.4567901234568, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6320314, Length=556, Percent_Identity=23.5611510791367, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321633, Length=333, Percent_Identity=24.024024024024, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24657106, Length=537, Percent_Identity=25.6983240223464, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24657102, Length=537, Percent_Identity=25.6983240223464, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24655555, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24655560, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24655570, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24655574, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24655565, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI17864214, Length=467, Percent_Identity=23.3404710920771, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI21356607, Length=470, Percent_Identity=26.5957446808511, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24654573, Length=392, Percent_Identity=23.9795918367347, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920476, Length=280, Percent_Identity=27.1428571428571, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356323, Length=431, Percent_Identity=25.9860788863109, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 53265; Mature: 53265

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYIGVDLGTSAVKLLLMDESGKVLNIVSKEYPISFPKPGWSEQNPCDWWEQTVAGLIEL
CEEEEEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TKDFDRSAVAGISFGGQMHGLVVLDENDNVIRPAILWNDGRTQKETDYLNNVIGKEKLSE
HHHCCHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LTGNIAFAGFTAPKILWLKANEPENFARIKKLMLPKDYIAYRMTGVFSTDYSDASGMLLL
HHCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCHHHHEEEEEEEECCCCCCCCEEEE
DVKNKCWSKEMLDICDVREEWLPGLYESSEKTGTLKADVACELGFPKDCIVAAGAGDNAA
ECCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCHHEEEECCCCCCE
AAIGTGTVGAGKCNLSLGTSGTLFITSDEFRVDSHNALHSFDHADGGYHLMGCMLSAASC
EEEECCCCCCCEEEEEECCCEEEEEECCCEEECCCCHHHCCCCCCCCHHHHHHHHHHCCC
NNWWMKDILHSDDFVNEQKPLEEDGRLGENHVYFLPYLMGERSPHNDPSARAAFIGMSMD
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCEEEEEECCCC
TDRADMLQAVFEGVAYGLRDSLEVAKSLGVAPKSTTICGGGAKSVLWRKIVANVMNMQVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEE
TVEVEEGPAYGGAILAAVANGCFENVEAAAAAIVRKKDTTMPSPQLVEKYEKGYAKFKQF
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
YPALKGKY
HHHHCCCC
>Mature Secondary Structure
MLYIGVDLGTSAVKLLLMDESGKVLNIVSKEYPISFPKPGWSEQNPCDWWEQTVAGLIEL
CEEEEEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TKDFDRSAVAGISFGGQMHGLVVLDENDNVIRPAILWNDGRTQKETDYLNNVIGKEKLSE
HHHCCHHHHHCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LTGNIAFAGFTAPKILWLKANEPENFARIKKLMLPKDYIAYRMTGVFSTDYSDASGMLLL
HHCCEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCHHHHEEEEEEEECCCCCCCCEEEE
DVKNKCWSKEMLDICDVREEWLPGLYESSEKTGTLKADVACELGFPKDCIVAAGAGDNAA
ECCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEEEEECCCCCHHEEEECCCCCCE
AAIGTGTVGAGKCNLSLGTSGTLFITSDEFRVDSHNALHSFDHADGGYHLMGCMLSAASC
EEEECCCCCCCEEEEEECCCEEEEEECCCEEECCCCHHHCCCCCCCCHHHHHHHHHHCCC
NNWWMKDILHSDDFVNEQKPLEEDGRLGENHVYFLPYLMGERSPHNDPSARAAFIGMSMD
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCEEEEEECCCC
TDRADMLQAVFEGVAYGLRDSLEVAKSLGVAPKSTTICGGGAKSVLWRKIVANVMNMQVD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHCCEEE
TVEVEEGPAYGGAILAAVANGCFENVEAAAAAIVRKKDTTMPSPQLVEKYEKGYAKFKQF
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
YPALKGKY
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 2994009 [H]